Compile Data Set for Download or QSAR

Found 131 hits with Last Name = 'koes' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polymerase acidic protein ()	BDBM474361 ((S)-6-benzhydryl-11-hydroxy-3-(1H-pyrazol- 4-yl)-5...) Show SMILES Oc1c2-c3ncc(-c4cn[nH]c4)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474361 ((S)-6-benzhydryl-11-hydroxy-3-(1H-pyrazol- 4-yl)-5...) Show SMILES Oc1c2-c3ncc(-c4cn[nH]c4)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474354 ((S)-6-((S)-(3-fluorophenyl)(4- fluorophenyl)methyl...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(F)c3)n2ncc1=O |r| Show InChI InChI=1S/C22H16F2N4O2/c23-15-6-4-13(5-7-15)19(14-2-1-3-16(24)10-14)17-12-27-9-8-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474346 ((S)-6-benzhydryl-3-bromo-11-hydroxy-5H- imidazo[1,...) Show SMILES Oc1c2-c3ncc(Br)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H18BrN3O2/c24-19-13-25-23-21-22(29)18(28)11-12-26(21)17(14-27(19)23)20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,17,20,29H,14H2/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474346 ((S)-6-benzhydryl-3-bromo-11-hydroxy-5H- imidazo[1,...) Show SMILES Oc1c2-c3ncc(Br)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H18BrN3O2/c24-19-13-25-23-21-22(29)18(28)11-12-26(21)17(14-27(19)23)20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,17,20,29H,14H2/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474354 ((S)-6-((S)-(3-fluorophenyl)(4- fluorophenyl)methyl...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(F)c3)n2ncc1=O |r| Show InChI InChI=1S/C22H16F2N4O2/c23-15-6-4-13(5-7-15)19(14-2-1-3-16(24)10-14)17-12-27-9-8-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474367 ((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(Br)c3)n2ncc1=O |r| Show InChI InChI=1S/C22H16BrFN4O2/c23-15-3-1-2-14(10-15)19(13-4-6-16(24)7-5-13)17-12-27-9-8-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474357 ((S)-6-((R)-(2-bromo-4-fluorophenyl)(4- fluoropheny...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@H](c3ccc(F)cc3)c3ccc(F)cc3Br)n2ncc1=O |r| Show InChI InChI=1S/C22H15BrF2N4O2/c23-16-9-14(25)5-6-15(16)19(12-1-3-13(24)4-2-12)17-11-28-8-7-26-22(28)20-21(31)18(30)10-27-29(17)20/h1-10,17,19,31H,11H2/t17-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474357 ((S)-6-((R)-(2-bromo-4-fluorophenyl)(4- fluoropheny...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@H](c3ccc(F)cc3)c3ccc(F)cc3Br)n2ncc1=O |r| Show InChI InChI=1S/C22H15BrF2N4O2/c23-16-9-14(25)5-6-15(16)19(12-1-3-13(24)4-2-12)17-11-28-8-7-26-22(28)20-21(31)18(30)10-27-29(17)20/h1-10,17,19,31H,11H2/t17-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474367 ((S)-6-((S)-(3-bromophenyl)(4- fluorophenyl)methyl)...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(Br)c3)n2ncc1=O |r| Show InChI InChI=1S/C22H16BrFN4O2/c23-15-3-1-2-14(10-15)19(13-4-6-16(24)7-5-13)17-12-27-9-8-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50525789 (CHEMBL4469854) Show SMILES O=C(Cc1ccccc1)Nc1nnc(OC2CCN(CC2)c2nnc(NC(=O)C3CC3)s2)s1 Show InChI InChI=1S/C21H23N7O3S2/c29-16(12-13-4-2-1-3-5-13)22-18-25-27-21(33-18)31-15-8-10-28(11-9-15)20-26-24-19(32-20)23-17(30)14-6-7-14/h1-5,14-15H,6-12H2,(H,22,25,29)(H,23,24,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 mins				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126632 BindingDB Entry DOI: 10.7270/Q29W0JX3
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474343 ((S)-6-Benzhydryl-11-hydroxy-5H- imidazo[1,2-a]pyri...) Show SMILES Oc1c2-c3nccn3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H19N3O2/c27-19-11-13-26-18(15-25-14-12-24-23(25)21(26)22(19)28)20(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,18,20,28H,15H2/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50525789 (CHEMBL4469854) Show SMILES O=C(Cc1ccccc1)Nc1nnc(OC2CCN(CC2)c2nnc(NC(=O)C3CC3)s2)s1 Show InChI InChI=1S/C21H23N7O3S2/c29-16(12-13-4-2-1-3-5-13)22-18-25-27-21(33-18)31-15-8-10-28(11-9-15)20-26-24-19(32-20)23-17(30)14-6-7-14/h1-5,14-15H,6-12H2,(H,22,25,29)(H,23,24,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 mins				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126632 BindingDB Entry DOI: 10.7270/Q29W0JX3
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474343 ((S)-6-Benzhydryl-11-hydroxy-5H- imidazo[1,2-a]pyri...) Show SMILES Oc1c2-c3nccn3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H19N3O2/c27-19-11-13-26-18(15-25-14-12-24-23(25)21(26)22(19)28)20(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,18,20,28H,15H2/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50525793 (CHEMBL4436129) Show SMILES O=C(Cc1ccccc1)Nc1nnc(OC2CCN(CC2)c2nnc(NC(=O)C3CCC3)s2)s1 Show InChI InChI=1S/C22H25N7O3S2/c30-17(13-14-5-2-1-3-6-14)23-19-26-28-22(34-19)32-16-9-11-29(12-10-16)21-27-25-20(33-21)24-18(31)15-7-4-8-15/h1-3,5-6,15-16H,4,7-13H2,(H,23,26,30)(H,24,25,31)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 mins				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126632 BindingDB Entry DOI: 10.7270/Q29W0JX3
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50525793 (CHEMBL4436129) Show SMILES O=C(Cc1ccccc1)Nc1nnc(OC2CCN(CC2)c2nnc(NC(=O)C3CCC3)s2)s1 Show InChI InChI=1S/C22H25N7O3S2/c30-17(13-14-5-2-1-3-6-14)23-19-26-28-22(34-19)32-16-9-11-29(12-10-16)21-27-25-20(33-21)24-18(31)15-7-4-8-15/h1-3,5-6,15-16H,4,7-13H2,(H,23,26,30)(H,24,25,31)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 mins				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126632 BindingDB Entry DOI: 10.7270/Q29W0JX3
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474355 ((S)-6-((S)-(4-chlorophenyl)(4- fluorophenyl)methyl...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3ccc(Cl)cc3)n2ncc1=O |r| Show InChI InChI=1S/C22H16ClFN4O2/c23-15-5-1-13(2-6-15)19(14-3-7-16(24)8-4-14)17-12-27-10-9-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474359 (3-((S)-(4-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(c3)C#N)n2ncc1=O |r| Show InChI InChI=1S/C23H16FN5O2/c24-17-6-4-15(5-7-17)20(16-3-1-2-14(10-16)11-25)18-13-28-9-8-26-23(28)21-22(31)19(30)12-27-29(18)21/h1-10,12,18,20,31H,13H2/t18-,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474350 ((S)-6-((S)-(4-fluorophenyl)(phenyl)methyl)- 11-hyd...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccccc3)c3ccc(F)cc3)n2ncc1=O |r| Show InChI InChI=1S/C22H17FN4O2/c23-16-8-6-15(7-9-16)19(14-4-2-1-3-5-14)17-13-26-11-10-24-22(26)20-21(29)18(28)12-25-27(17)20/h1-12,17,19,29H,13H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474349 ((S)-6-((R)-(4-fluorophenyl)(phenyl)methyl)- 11-hyd...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@H](c3ccccc3)c3ccc(F)cc3)n2ncc1=O |r| Show InChI InChI=1S/C22H17FN4O2/c23-16-8-6-15(7-9-16)19(14-4-2-1-3-5-14)17-13-26-11-10-24-22(26)20-21(29)18(28)12-25-27(17)20/h1-12,17,19,29H,13H2/t17-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474344 ((S)-6-Benzhydryl-3-chloro-11-hydroxy-5,6- dihydro-...) Show SMILES Oc1c2-c3ncc(Cl)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H18ClN3O2/c24-19-13-25-23-21-22(29)18(28)11-12-26(21)17(14-27(19)23)20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,17,20,29H,14H2/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474344 ((S)-6-Benzhydryl-3-chloro-11-hydroxy-5,6- dihydro-...) Show SMILES Oc1c2-c3ncc(Cl)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C23H18ClN3O2/c24-19-13-25-23-21-22(29)18(28)11-12-26(21)17(14-27(19)23)20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,17,20,29H,14H2/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474349 ((S)-6-((R)-(4-fluorophenyl)(phenyl)methyl)- 11-hyd...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@H](c3ccccc3)c3ccc(F)cc3)n2ncc1=O |r| Show InChI InChI=1S/C22H17FN4O2/c23-16-8-6-15(7-9-16)19(14-4-2-1-3-5-14)17-13-26-11-10-24-22(26)20-21(29)18(28)12-25-27(17)20/h1-12,17,19,29H,13H2/t17-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474355 ((S)-6-((S)-(4-chlorophenyl)(4- fluorophenyl)methyl...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3ccc(Cl)cc3)n2ncc1=O |r| Show InChI InChI=1S/C22H16ClFN4O2/c23-15-5-1-13(2-6-15)19(14-3-7-16(24)8-4-14)17-12-27-10-9-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-,19-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474350 ((S)-6-((S)-(4-fluorophenyl)(phenyl)methyl)- 11-hyd...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccccc3)c3ccc(F)cc3)n2ncc1=O |r| Show InChI InChI=1S/C22H17FN4O2/c23-16-8-6-15(7-9-16)19(14-4-2-1-3-5-14)17-13-26-11-10-24-22(26)20-21(29)18(28)12-25-27(17)20/h1-12,17,19,29H,13H2/t17-,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474358 ((S)-6-((S)-(4-fluorophenyl)(o-tolyl)methyl)-11- hy...) Show SMILES Cc1ccccc1[C@@H]([C@H]1Cn2ccnc2-c2c(O)c(=O)cnn12)c1ccc(F)cc1 |r| Show InChI InChI=1S/C23H19FN4O2/c1-14-4-2-3-5-17(14)20(15-6-8-16(24)9-7-15)18-13-27-11-10-25-23(27)21-22(30)19(29)12-26-28(18)21/h2-12,18,20,30H,13H2,1H3/t18-,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474359 (3-((S)-(4-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3ccc(F)cc3)c3cccc(c3)C#N)n2ncc1=O |r| Show InChI InChI=1S/C23H16FN5O2/c24-17-6-4-15(5-7-17)20(16-3-1-2-14(10-16)11-25)18-13-28-9-8-26-23(28)21-22(31)19(30)12-27-29(18)21/h1-10,12,18,20,31H,13H2/t18-,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474358 ((S)-6-((S)-(4-fluorophenyl)(o-tolyl)methyl)-11- hy...) Show SMILES Cc1ccccc1[C@@H]([C@H]1Cn2ccnc2-c2c(O)c(=O)cnn12)c1ccc(F)cc1 |r| Show InChI InChI=1S/C23H19FN4O2/c1-14-4-2-3-5-17(14)20(15-6-8-16(24)9-7-15)18-13-27-11-10-25-23(27)21-22(30)19(29)12-26-28(18)21/h2-12,18,20,30H,13H2,1H3/t18-,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50525797 (CHEMBL4524344) Show SMILES CC(C)C(=O)Nc1nnc(s1)N1CCC(CC1)Oc1nnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C21H25N7O3S2/c1-13(2)17(30)23-19-24-26-20(32-19)28-10-8-15(9-11-28)31-21-27-25-18(33-21)22-16(29)12-14-6-4-3-5-7-14/h3-7,13,15H,8-12H2,1-2H3,(H,22,25,29)(H,23,24,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 mins				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126632 BindingDB Entry DOI: 10.7270/Q29W0JX3
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50525797 (CHEMBL4524344) Show SMILES CC(C)C(=O)Nc1nnc(s1)N1CCC(CC1)Oc1nnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C21H25N7O3S2/c1-13(2)17(30)23-19-24-26-20(32-19)28-10-8-15(9-11-28)31-21-27-25-18(33-21)22-16(29)12-14-6-4-3-5-7-14/h3-7,13,15H,8-12H2,1-2H3,(H,22,25,29)(H,23,24,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 mins				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126632 BindingDB Entry DOI: 10.7270/Q29W0JX3
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50525795 (CHEMBL4459383) Show SMILES O=C(CC1CC1)Nc1nnc(s1)N1CCC(CC1)Oc1nnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C22H25N7O3S2/c30-17(12-14-4-2-1-3-5-14)24-20-26-28-22(34-20)32-16-8-10-29(11-9-16)21-27-25-19(33-21)23-18(31)13-15-6-7-15/h1-5,15-16H,6-13H2,(H,23,25,31)(H,24,26,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 mins				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126632 BindingDB Entry DOI: 10.7270/Q29W0JX3
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50525795 (CHEMBL4459383) Show SMILES O=C(CC1CC1)Nc1nnc(s1)N1CCC(CC1)Oc1nnc(NC(=O)Cc2ccccc2)s1 Show InChI InChI=1S/C22H25N7O3S2/c30-17(12-14-4-2-1-3-5-14)24-20-26-28-22(34-20)32-16-8-10-29(11-9-16)21-27-25-19(33-21)23-18(31)13-15-6-7-15/h1-5,15-16H,6-13H2,(H,23,25,31)(H,24,26,30)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 mins				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126632 BindingDB Entry DOI: 10.7270/Q29W0JX3
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50525790 (CHEMBL4578823) Show SMILES CC(C)(C)C(=O)Nc1nnc(OC2CCN(CC2)c2nnc(NC(=O)Cc3ccccc3)s2)s1 Show InChI InChI=1S/C22H27N7O3S2/c1-22(2,3)17(31)24-19-26-28-21(34-19)32-15-9-11-29(12-10-15)20-27-25-18(33-20)23-16(30)13-14-7-5-4-6-8-14/h4-8,15H,9-13H2,1-3H3,(H,23,25,30)(H,24,26,31)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 mins				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126632 BindingDB Entry DOI: 10.7270/Q29W0JX3
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50525790 (CHEMBL4578823) Show SMILES CC(C)(C)C(=O)Nc1nnc(OC2CCN(CC2)c2nnc(NC(=O)Cc3ccccc3)s2)s1 Show InChI InChI=1S/C22H27N7O3S2/c1-22(2,3)17(31)24-19-26-28-21(34-19)32-15-9-11-29(12-10-15)20-27-25-18(33-20)23-16(30)13-14-7-5-4-6-8-14/h4-8,15H,9-13H2,1-3H3,(H,23,25,30)(H,24,26,31)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 mins				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126632 BindingDB Entry DOI: 10.7270/Q29W0JX3
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474351 ((S)-6-((R)-(4-fluorophenyl)(5-fluoropyridin-3- yl)...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@H](c3ccc(F)cc3)c3cncc(F)c3)n2ncc1=O |r| Show InChI InChI=1S/C21H15F2N5O2/c22-14-3-1-12(2-4-14)18(13-7-15(23)9-24-8-13)16-11-27-6-5-25-21(27)19-20(30)17(29)10-26-28(16)19/h1-10,16,18,30H,11H2/t16-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474347 ((S)-6-benzhydryl-3-cyclopropyl-11-hydroxy- 5H-imid...) Show SMILES Oc1c2-c3ncc(C4CC4)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C26H23N3O2/c30-22-13-14-28-21(23(18-7-3-1-4-8-18)19-9-5-2-6-10-19)16-29-20(17-11-12-17)15-27-26(29)24(28)25(22)31/h1-10,13-15,17,21,23,31H,11-12,16H2/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474345 (6-benzhydryl-11-hydroxy-5,6-dihydro-10H- imidazo[1...) Show SMILES Oc1c2-c3nccn3CN(C(c3ccccc3)c3ccccc3)n2ccc1=O Show InChI InChI=1S/C22H18N4O2/c27-18-11-13-25-20(21(18)28)22-23-12-14-24(22)15-26(25)19(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,19,28H,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474366 (6-benzhydryl-5-ethyl-11-hydroxy-5,6-dihydro- 10H-i...) Show SMILES CCC1N(C(c2ccccc2)c2ccccc2)n2ccc(=O)c(O)c2-c2nccn12 Show InChI InChI=1S/C24H22N4O2/c1-2-20-26-16-14-25-24(26)22-23(30)19(29)13-15-27(22)28(20)21(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-16,20-21,30H,2H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474364 ((S)-6-benzhydryl-3-(difluoromethyl)-11- hydroxy-5,...) Show SMILES Oc1c2-c3ncc(C(F)F)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C24H19F2N3O2/c25-23(26)17-13-27-24-21-22(31)19(30)11-12-28(21)18(14-29(17)24)20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,18,20,23,31H,14H2/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474356 ((S)-6-((S)-(4-fluorophenyl)(m-tolyl)methyl)- 11-hy...) Show SMILES Cc1cccc(c1)[C@@H]([C@H]1Cn2ccnc2-c2c(O)c(=O)cnn12)c1ccc(F)cc1 |r| Show InChI InChI=1S/C23H19FN4O2/c1-14-3-2-4-16(11-14)20(15-5-7-17(24)8-6-15)18-13-27-10-9-25-23(27)21-22(30)19(29)12-26-28(18)21/h2-12,18,20,30H,13H2,1H3/t18-,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474351 ((S)-6-((R)-(4-fluorophenyl)(5-fluoropyridin-3- yl)...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@H](c3ccc(F)cc3)c3cncc(F)c3)n2ncc1=O |r| Show InChI InChI=1S/C21H15F2N5O2/c22-14-3-1-12(2-4-14)18(13-7-15(23)9-24-8-13)16-11-27-6-5-25-21(27)19-20(30)17(29)10-26-28(16)19/h1-10,16,18,30H,11H2/t16-,18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474347 ((S)-6-benzhydryl-3-cyclopropyl-11-hydroxy- 5H-imid...) Show SMILES Oc1c2-c3ncc(C4CC4)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C26H23N3O2/c30-22-13-14-28-21(23(18-7-3-1-4-8-18)19-9-5-2-6-10-19)16-29-20(17-11-12-17)15-27-26(29)24(28)25(22)31/h1-10,13-15,17,21,23,31H,11-12,16H2/t21-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474345 (6-benzhydryl-11-hydroxy-5,6-dihydro-10H- imidazo[1...) Show SMILES Oc1c2-c3nccn3CN(C(c3ccccc3)c3ccccc3)n2ccc1=O Show InChI InChI=1S/C22H18N4O2/c27-18-11-13-25-20(21(18)28)22-23-12-14-24(22)15-26(25)19(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,19,28H,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474366 (6-benzhydryl-5-ethyl-11-hydroxy-5,6-dihydro- 10H-i...) Show SMILES CCC1N(C(c2ccccc2)c2ccccc2)n2ccc(=O)c(O)c2-c2nccn12 Show InChI InChI=1S/C24H22N4O2/c1-2-20-26-16-14-25-24(26)22-23(30)19(29)13-15-27(22)28(20)21(17-9-5-3-6-10-17)18-11-7-4-8-12-18/h3-16,20-21,30H,2H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474364 ((S)-6-benzhydryl-3-(difluoromethyl)-11- hydroxy-5,...) Show SMILES Oc1c2-c3ncc(C(F)F)n3C[C@H](C(c3ccccc3)c3ccccc3)n2ccc1=O |r| Show InChI InChI=1S/C24H19F2N3O2/c25-23(26)17-13-27-24-21-22(31)19(30)11-12-28(21)18(14-29(17)24)20(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,18,20,23,31H,14H2/t18-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474356 ((S)-6-((S)-(4-fluorophenyl)(m-tolyl)methyl)- 11-hy...) Show SMILES Cc1cccc(c1)[C@@H]([C@H]1Cn2ccnc2-c2c(O)c(=O)cnn12)c1ccc(F)cc1 |r| Show InChI InChI=1S/C23H19FN4O2/c1-14-3-2-4-16(11-14)20(15-5-7-17(24)8-6-15)18-13-27-10-9-25-23(27)21-22(30)19(29)12-26-28(18)21/h2-12,18,20,30H,13H2,1H3/t18-,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474340 (6-Benzhydryl-11-hydroxy-5H- imidazo[2',1':3,4]pyra...) Show SMILES Oc1c2-c3nccn3CC(C(c3ccccc3)c3ccccc3)n2ncc1=O Show InChI InChI=1S/C22H18N4O2/c27-18-13-24-26-17(14-25-12-11-23-22(25)20(26)21(18)28)19(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,17,19,28H,14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				US Patent US10858366 (2020) BindingDB Entry DOI: 10.7270/Q2KH0RDJ
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474360 (3-((R)-(3-fluorophenyl)((S)-11-hydroxy-10- oxo-5,6...) Show SMILES Oc1c2-c3nccn3C[C@H]([C@@H](c3cccc(F)c3)c3cccc(c3)C#N)n2ncc1=O |r| Show InChI InChI=1S/C23H16FN5O2/c24-17-6-2-5-16(10-17)20(15-4-1-3-14(9-15)11-25)18-13-28-8-7-26-23(28)21-22(31)19(30)12-27-29(18)21/h1-10,12,18,20,31H,13H2/t18-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474340 (6-Benzhydryl-11-hydroxy-5H- imidazo[2',1':3,4]pyra...) Show SMILES Oc1c2-c3nccn3CC(C(c3ccccc3)c3ccccc3)n2ncc1=O Show InChI InChI=1S/C22H18N4O2/c27-18-13-24-26-17(14-25-12-11-23-22(25)20(26)21(18)28)19(15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,17,19,28H,14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair
Polymerase acidic protein ()	BDBM474353 ((S)-6-(bis(3-fluorophenyl)methyl)-11- hydroxy-5,6-...) Show SMILES Oc1c2-c3nccn3C[C@H](C(c3cccc(F)c3)c3cccc(F)c3)n2ncc1=O |r| Show InChI InChI=1S/C22H16F2N4O2/c23-15-5-1-3-13(9-15)19(14-4-2-6-16(24)10-14)17-12-27-8-7-25-22(27)20-21(30)18(29)11-26-28(17)20/h1-11,17,19,30H,12H2/t17-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds were dissolved and serially diluted in 100% DMSO then 0.5 μl was transferred to 384-well plates. 50 nM truncated Influenza A/victoria/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2Z60S8G
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 131 total )  |  Next  |  Last  >>

Jump to: