Compile Data Set for Download or QSAR

Found 117 hits with Last Name = 'schlenzig' and Initial = 'd'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Meprin A subunit beta (Homo sapiens)	BDBM50240418 (CHEMBL4096803) Show SMILES [Na+].[Na+].[Na+].[Na+].Cc1nc(\N=N\c2cc(c3cc(cc(c3c2)S([O-])(=O)=O)[N+]([O-])=O)S([O-])(=O)=O)c(COP([O-])([O-])=O)c(C(O)=O)c1O Show InChI InChI=1S/C18H15N4O15PS2/c1-7-16(23)15(18(24)25)12(6-37-38(28,29)30)17(19-7)21-20-8-2-10-11(13(3-8)39(31,32)33)4-9(22(26)27)5-14(10)40(34,35)36/h2-5,23H,6H2,1H3,(H,24,25)(H2,28,29,30)(H,31,32,33)(H,34,35,36)/p-4/b21-20+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in baculovirus infected Sf9 insect cells using (MCA)-EDEDED-(K-epsilon-dnp) as substrate by flu...				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240455 (CHEMBL1253351) Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[O-]S(=O)(=O)c1ccc(NC(=O)c2cc(NC(=O)Nc3cc(cc(c3)C(=O)Nc3ccc(cc3S([O-])(=O)=O)S([O-])(=O)=O)C(=O)Nc3ccc(cc3S([O-])(=O)=O)S([O-])(=O)=O)cc(c2)C(=O)Nc2ccc(cc2S([O-])(=O)=O)S([O-])(=O)=O)c(c1)S([O-])(=O)=O Show InChI InChI=1S/C41H32N6O29S8/c48-37(44-29-5-1-25(77(53,54)55)15-33(29)81(65,66)67)19-9-20(38(49)45-30-6-2-26(78(56,57)58)16-34(30)82(68,69)70)12-23(11-19)42-41(52)43-24-13-21(39(50)46-31-7-3-27(79(59,60)61)17-35(31)83(71,72)73)10-22(14-24)40(51)47-32-8-4-28(80(62,63)64)18-36(32)84(74,75)76/h1-18H,(H,44,48)(H,45,49)(H,46,50)(H,47,51)(H2,42,43,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)/p-8	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in baculovirus infected Sf9 insect cells using (MCA)-EDEDED-(K-epsilon-dnp) as substrate by flu...				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50089194 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...) Show SMILES CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO Show InChI InChI=1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)/t14-,15+,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of human meprin beta expressed in baculovirus infected BTI-TN-5B1-4 insect cells using N-benzoyl-L-tyrosylp-aminobenzoic acid as substrate				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50089194 ((R)-N*4*-Hydroxy-N*1*-[(S)-1-((S)-2-hydroxymethyl-...) Show SMILES CCCCC[C@H](CC(=O)NO)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1CO Show InChI InChI=1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)/t14-,15+,17+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in baculovirus infected insect cells using N-benzoyl-L-tyrosyl-p-aminobenzoic acid as substrate				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM13080 (CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO Show InChI InChI=1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in baculovirus infected insect cells using N-benzoyl-L-tyrosyl-p-aminobenzoic acid as substrate				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM13080 (CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO Show InChI InChI=1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of human meprin beta expressed in baculovirus infected BTI-TN-5B1-4 insect cells using N-benzoyl-L-tyrosylp-aminobenzoic acid as substrate				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM50240415 (CHEMBL4078433) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C17H18N2O7S/c1-26-14-5-7-15(8-6-14)27(24,25)19(11-16(20)18-23)10-12-3-2-4-13(9-12)17(21)22/h2-9,23H,10-11H2,1H3,(H,18,20)(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of APMA-activated recombinant human MMP13 expressed in mouse NS0 cells using Mca-PLGL-(DapDnp)-AR-NH2 as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50240415 (CHEMBL4078433) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C17H18N2O7S/c1-26-14-5-7-15(8-6-14)27(24,25)19(11-16(20)18-23)10-12-3-2-4-13(9-12)17(21)22/h2-9,23H,10-11H2,1H3,(H,18,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of APMA-activated recombinant human MMP2 expressed in CHO cells using Mca-PLGL-(DapDnp)-AR-NH2 as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI InChI=1S/C13H14N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Plant Biochemistry Curated by ChEMBL					Assay Description Inhibition of equine serum BChE by Ellman's method				Bioorg Med Chem 18: 2173-7 (2010) Article DOI: 10.1016/j.bmc.2010.01.074 BindingDB Entry DOI: 10.7270/Q2R78G5X
					More data for this Ligand-Target Pair				3D Structure (crystal)
Meprin A subunit beta (Homo sapiens)	BDBM50455676 (CHEMBL4209993) Show SMILES ONC(=O)CN(Cc1ccc(F)c(O)c1F)Cc1ccc(F)c(O)c1F Show InChI InChI=1S/C16H21N3O4S3.ClH/c1-18-6-8-19(9-7-18)11-13-4-2-3-5-15(13)25(20,21)14-10-16(24-12-14)26(17,22)23;/h2-5,10,12H,6-9,11H2,1H3,(H2,17,22,23);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455648 (CHEMBL4205925) Show SMILES ONC(=O)CN(Cc1ccc(Cl)c(O)c1F)Cc1ccc(Cl)c(O)c1F Show InChI InChI=1S/C16H14Cl2F2N2O4/c17-10-3-1-8(13(19)15(10)24)5-22(7-12(23)21-26)6-9-2-4-11(18)16(25)14(9)20/h1-4,24-26H,5-7H2,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455658 (CHEMBL4216076) Show SMILES ONC(=O)CN(Cc1cccc(c1)C(O)=O)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C18H18N2O6/c21-16(19-26)11-20(9-12-3-1-5-14(7-12)17(22)23)10-13-4-2-6-15(8-13)18(24)25/h1-8,26H,9-11H2,(H,19,21)(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair				3D Structure (crystal)
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50240415 (CHEMBL4078433) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C17H18N2O7S/c1-26-14-5-7-15(8-6-14)27(24,25)19(11-16(20)18-23)10-12-3-2-4-13(9-12)17(21)22/h2-9,23H,10-11H2,1H3,(H,18,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of APMA-activated recombinant human MMP9 expressed in CHO cells using Mca-PLGL-(DapDnp)-AR-NH2 as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240415 (CHEMBL4078433) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C17H18N2O7S/c1-26-14-5-7-15(8-6-14)27(24,25)19(11-16(20)18-23)10-12-3-2-4-13(9-12)17(21)22/h2-9,23H,10-11H2,1H3,(H,18,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240414 (CHEMBL4105563) Show SMILES ONC(=O)CN(Cc1cccc(c1)C(O)=O)S(=O)(=O)c1cccc(c1)C(O)=O Show InChI InChI=1S/C17H16N2O8S/c20-15(18-25)10-19(9-11-3-1-4-12(7-11)16(21)22)28(26,27)14-6-2-5-13(8-14)17(23)24/h1-8,25H,9-10H2,(H,18,20)(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240415 (CHEMBL4078433) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C17H18N2O7S/c1-26-14-5-7-15(8-6-14)27(24,25)19(11-16(20)18-23)10-12-3-2-4-13(9-12)17(21)22/h2-9,23H,10-11H2,1H3,(H,18,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455682 (CHEMBL4206683) Show SMILES ONC(=O)CN(Cc1ccc(Cl)cc1)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C19H18N2O3S2.ClH/c20-26(23,24)18-10-17(13-25-18)19(22)16-8-6-15(7-9-16)12-21-11-14-4-2-1-3-5-14;/h1-10,13,21H,11-12H2,(H2,20,23,24);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455674 (CHEMBL4217240) Show SMILES COc1ccc(CN(CC(=O)NO)Cc2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C11H11NO5S3/c1-17-8-2-4-9(5-3-8)19(13,14)10-6-11(18-7-10)20(12,15)16/h2-7H,1H3,(H2,12,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455668 (CHEMBL4207946) Show SMILES ONC(=O)CN(Cc1ccc(F)cc1)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C15H20N2O4S3.ClH/c1-11(2)8-17-9-12-4-3-5-13(6-12)23(18,19)14-7-15(22-10-14)24(16,20)21;/h3-7,10-11,17H,8-9H2,1-2H3,(H2,16,20,21);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	177	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455667 (CHEMBL4204835) Show SMILES ONC(=O)CN(Cc1ccc(cc1)C(O)=O)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C12H11NO5S/c1-17-10-4-2-8(3-5-10)12(14)9-6-11(18-7-9)19(13,15)16/h2-7H,1H3,(H2,13,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	207	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240465 (CHEMBL4099123) Show SMILES ONC(=O)CCNS(=O)(=O)c1cccc(c1)C(O)=O Show InChI InChI=1S/C10H12N2O6S/c13-9(12-16)4-5-11-19(17,18)8-3-1-2-7(6-8)10(14)15/h1-3,6,11,16H,4-5H2,(H,12,13)(H,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240405 (CHEMBL4102689) Show SMILES ONC(=O)CN(Cc1cccc(c1)C(O)=O)S(=O)(=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C17H16N2O8S/c20-16(18-23)9-19(8-11-2-1-3-12(6-11)17(21)22)28(24,25)13-4-5-14-15(7-13)27-10-26-14/h1-7,23H,8-10H2,(H,18,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455654 (CHEMBL4206728) Show SMILES ONC(=O)CN(Cc1cc(F)c(O)c(F)c1)Cc1cc(F)c(O)c(F)c1 Show InChI InChI=1S/C16H14F4N2O4/c17-10-1-8(2-11(18)15(10)24)5-22(7-14(23)21-26)6-9-3-12(19)16(25)13(20)4-9/h1-4,24-26H,5-7H2,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	272	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455683 (CHEMBL4215019) Show SMILES ONC(=O)CN(Cc1ccc2OCOc2c1)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C16H20N2O3S2.ClH/c1-2-3-8-18-10-12-4-6-13(7-5-12)16(19)14-9-15(22-11-14)23(17,20)21;/h4-7,9,11,18H,2-3,8,10H2,1H3,(H2,17,20,21);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	285	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240445 (CHEMBL4083600) Show SMILES ONC(=O)CNS(=O)(=O)c1cccc(c1)C(O)=O Show InChI InChI=1S/C9H10N2O6S/c12-8(11-15)5-10-18(16,17)7-3-1-2-6(4-7)9(13)14/h1-4,10,15H,5H2,(H,11,12)(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455644 (CHEMBL4207739) Show SMILES ONC(=O)CN(Cc1ccc(cc1)C#N)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C18H17N3O4/c19-9-13-4-6-14(7-5-13)10-21(12-17(22)20-25)11-15-2-1-3-16(8-15)18(23)24/h1-8,25H,10-12H2,(H,20,22)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240417 (CHEMBL4087683) Show SMILES ONC(=O)CN(Cc1cccc(c1)C(O)=O)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C17H16N2O8S/c20-15(18-25)10-19(9-11-2-1-3-13(8-11)17(23)24)28(26,27)14-6-4-12(5-7-14)16(21)22/h1-8,25H,9-10H2,(H,18,20)(H,21,22)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240454 (CHEMBL4072148) Show SMILES ONC(=O)CCNS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C10H12N2O6S/c13-9(12-16)5-6-11-19(17,18)8-3-1-7(2-4-8)10(14)15/h1-4,11,16H,5-6H2,(H,12,13)(H,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455670 (CHEMBL4218599) Show SMILES COc1cc(F)c(CN(CC(=O)NO)Cc2cccc(c2)C(O)=O)c(F)c1 Show InChI InChI=1S/C15H20N2O4S3.ClH/c1-15(2,3)17-9-11-4-6-12(7-5-11)23(18,19)13-8-14(22-10-13)24(16,20)21;/h4-8,10,17H,9H2,1-3H3,(H2,16,20,21);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit alpha (Homo sapiens)	BDBM50455648 (CHEMBL4205925) Show SMILES ONC(=O)CN(Cc1ccc(Cl)c(O)c1F)Cc1ccc(Cl)c(O)c1F Show InChI InChI=1S/C16H14Cl2F2N2O4/c17-10-3-1-8(13(19)15(10)24)5-22(7-12(23)21-26)6-9-2-4-11(18)16(25)14(9)20/h1-4,24-26H,5-7H2,(H,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	368	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin alpha expressed in insect cells using Abz-YVADAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455645 (CHEMBL4204272) Show SMILES COc1ccc(CN(CC(=O)NO)Cc2cccc(c2)C(O)=O)cc1F Show InChI InChI=1S/C18H19FN2O5/c1-26-16-6-5-13(8-15(16)19)10-21(11-17(22)20-25)9-12-3-2-4-14(7-12)18(23)24/h2-8,25H,9-11H2,1H3,(H,20,22)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	375	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455665 (CHEMBL4210875) Show SMILES ONC(=O)CNCc1cccc(c1)C(O)=O Show InChI InChI=1S/C10H12N2O4/c13-9(12-16)6-11-5-7-2-1-3-8(4-7)10(14)15/h1-4,11,16H,5-6H2,(H,12,13)(H,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455669 (CHEMBL4208444) Show SMILES Cc1ccc(CN(CC(=O)NO)Cc2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C11H9NO4S2/c12-18(15,16)10-5-8(6-17-10)11(14)7-1-3-9(13)4-2-7/h1-6,13H,(H2,12,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	386	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240397 (CHEMBL4096428) Show SMILES ONC(=O)CCNS(=O)(=O)c1cc(Cl)c(O)c(Cl)c1 Show InChI InChI=1S/C9H10Cl2N2O5S/c10-6-3-5(4-7(11)9(6)15)19(17,18)12-2-1-8(14)13-16/h3-4,12,15-16H,1-2H2,(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240443 (CHEMBL4101604) Show SMILES ONC(=O)CNS(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C9H10N2O6S/c12-8(11-15)5-10-18(16,17)7-3-1-6(2-4-7)9(13)14/h1-4,10,15H,5H2,(H,11,12)(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description In vitro inhibitory activity against Aldose reductase isolated from human placenta				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240450 (CHEMBL4063534) Show SMILES ONC(=O)CNS(=O)(=O)c1cc(Cl)c(O)c(Cl)c1 Show InChI InChI=1S/C8H8Cl2N2O5S/c9-5-1-4(2-6(10)8(5)14)18(16,17)11-3-7(13)12-15/h1-2,11,14-15H,3H2,(H,12,13)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455678 (CHEMBL4209047) Show SMILES ONC(=O)CN(Cc1ccc(cc1)C(O)=O)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C12H11NO4S2/c1-17-10-4-2-8(3-5-10)12(14)9-6-11(18-7-9)19(13,15)16/h2-7H,1H3,(H2,13,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	524	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455660 (CHEMBL4206648) Show SMILES ONC(=O)[C@@H](CC(O)=O)NCc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C12H14N2O6/c15-10(16)5-9(11(17)14-20)13-6-7-2-1-3-8(4-7)12(18)19/h1-4,9,13,20H,5-6H2,(H,14,17)(H,15,16)(H,18,19)/t9-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	548	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455672 (CHEMBL4214841) Show SMILES COc1cccc(CN(CC(=O)NO)Cc2cccc(c2)C(O)=O)c1 Show InChI InChI=1S/C16H22N2O5S3.ClH/c1-11(2)8-18(3)9-12-6-13(4-5-15(12)19)25(20,21)14-7-16(24-10-14)26(17,22)23;/h4-7,10-11,19H,8-9H2,1-3H3,(H2,17,22,23);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	559	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit alpha (Homo sapiens)	BDBM50455676 (CHEMBL4209993) Show SMILES ONC(=O)CN(Cc1ccc(F)c(O)c1F)Cc1ccc(F)c(O)c1F Show InChI InChI=1S/C16H21N3O4S3.ClH/c1-18-6-8-19(9-7-18)11-13-4-2-3-5-15(13)25(20,21)14-10-16(24-12-14)26(17,22)23;/h2-5,10,12H,6-9,11H2,1H3,(H2,17,22,23);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	626	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin alpha expressed in insect cells using Abz-YVADAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455650 (CHEMBL4216704) Show SMILES COc1ccc(CN(CCC(=O)NO)Cc2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C19H22N2O5/c1-26-17-7-5-14(6-8-17)12-21(10-9-18(22)20-25)13-15-3-2-4-16(11-15)19(23)24/h2-8,11,25H,9-10,12-13H2,1H3,(H,20,22)(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	643	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240409 (CHEMBL4067530) Show SMILES COc1ccc(cc1F)S(=O)(=O)N(CC(=O)NO)Cc1cccc(c1)C(O)=O Show InChI InChI=1S/C17H17FN2O7S/c1-27-15-6-5-13(8-14(15)18)28(25,26)20(10-16(21)19-24)9-11-3-2-4-12(7-11)17(22)23/h2-8,24H,9-10H2,1H3,(H,19,21)(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455643 (CHEMBL4214445) Show SMILES ONC(=O)[C@H](CCC(O)=O)NCc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C13H16N2O6/c16-11(17)5-4-10(12(18)15-21)14-7-8-2-1-3-9(6-8)13(19)20/h1-3,6,10,14,21H,4-5,7H2,(H,15,18)(H,16,17)(H,19,20)/t10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	654	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240468 (CHEMBL4083361) Show SMILES ONC(=O)CN(Cc1cccc(c1)C(O)=O)S(=O)(=O)c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C17H15F3N2O7S/c18-17(19,20)29-13-4-6-14(7-5-13)30(27,28)22(10-15(23)21-26)9-11-2-1-3-12(8-11)16(24)25/h1-8,26H,9-10H2,(H,21,23)(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bos taurus (bovine))	BDBM8961 (1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...) Show SMILES Nc1c2CCCCc2nc2ccccc12 Show InChI InChI=1S/C13H14N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,14,15)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Plant Biochemistry Curated by ChEMBL					Assay Description Inhibition of bovine AChE by Elman's method				Bioorg Med Chem 18: 2173-7 (2010) Article DOI: 10.1016/j.bmc.2010.01.074 BindingDB Entry DOI: 10.7270/Q2R78G5X
					More data for this Ligand-Target Pair				3D Structure (crystal)
Meprin A subunit beta (Homo sapiens)	BDBM50455673 (CHEMBL4218003) Show SMILES COc1ccc(CN(CCCC(=O)NO)Cc2cccc(c2)C(O)=O)cc1 Show InChI InChI=1S/C16H20N2O3S2.ClH/c1-11(2)8-18-9-12-3-5-13(6-4-12)16(19)14-7-15(22-10-14)23(17,20)21;/h3-7,10-11,18H,8-9H2,1-2H3,(H2,17,20,21);1H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	742	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50455659 (CHEMBL4209523) Show SMILES ONC(=O)[C@@H](CCC(O)=O)NCc1cccc(c1)C(O)=O |r| Show InChI InChI=1S/C13H16N2O6/c16-11(17)5-4-10(12(18)15-21)14-7-8-2-1-3-9(6-8)13(19)20/h1-3,6,10,14,21H,4-5,7H2,(H,15,18)(H,16,17)(H,19,20)/t10-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	768	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit alpha (Homo sapiens)	BDBM50455655 (CHEMBL4217178) Show SMILES ONC(=O)CN(Cc1ccc2OCOc2c1)Cc1ccc2OCOc2c1 Show InChI InChI=1S/C18H18N2O6/c21-18(19-22)9-20(7-12-1-3-14-16(5-12)25-10-23-14)8-13-2-4-15-17(6-13)26-11-24-15/h1-6,22H,7-11H2,(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of meprin alpha (unknown origin)				J Med Chem 61: 4578-4592 (2018) Article DOI: 10.1021/acs.jmedchem.8b00330 BindingDB Entry DOI: 10.7270/Q2KS6V47
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240403 (CHEMBL4079395) Show SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1ccc(cc1)C(O)=O Show InChI InChI=1S/C17H18N2O7S/c1-26-14-6-8-15(9-7-14)27(24,25)19(11-16(20)18-23)10-12-2-4-13(5-3-12)17(21)22/h2-9,23H,10-11H2,1H3,(H,18,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair
Meprin A subunit beta (Homo sapiens)	BDBM50240413 (CHEMBL4098334) Show SMILES ONC(=O)CN(Cc1cccc(c1)C(O)=O)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C16H15FN2O6S/c17-13-4-6-14(7-5-13)26(24,25)19(10-15(20)18-23)9-11-2-1-3-12(8-11)16(21)22/h1-8,23H,9-10H2,(H,18,20)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fraunhofer Institute for Cell Therapy and Immunology IZI Curated by ChEMBL					Assay Description Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay				Bioorg Med Chem Lett 27: 2428-2431 (2017) Article DOI: 10.1016/j.bmcl.2017.04.012 BindingDB Entry DOI: 10.7270/Q2CR5WH0
					More data for this Ligand-Target Pair

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