Compile Data Set for Download or QSAR

Found 7 hits with Last Name = 'chang' and Initial = 'dm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor ligand superfamily member 11 (Mus musculus)	BDBM50108929 (CHEMBL3596956) Show SMILES Fc1ccc(c(F)c1)-c1ccc2oc(=O)n(-c3cccc(c3)C#C)c(=O)c2c1 Show InChI InChI=1S/C22H11F2NO3/c1-2-13-4-3-5-16(10-13)25-21(26)18-11-14(6-9-20(18)28-22(25)27)17-8-7-15(23)12-19(17)24/h1,3-12H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...				Bioorg Med Chem 23: 4522-32 (2015) Article DOI: 10.1016/j.bmc.2015.06.007 BindingDB Entry DOI: 10.7270/Q2V126KK
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Mus musculus)	BDBM50108928 (CHEMBL3596954) Show SMILES Fc1ccc(c(F)c1)-c1ccc2oc(=O)n(-c3cccc(c3)C(F)(F)F)c(=O)c2c1 Show InChI InChI=1S/C21H10F5NO3/c22-13-5-6-15(17(23)10-13)11-4-7-18-16(8-11)19(28)27(20(29)30-18)14-3-1-2-12(9-14)21(24,25)26/h1-10H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...				Bioorg Med Chem 23: 4522-32 (2015) Article DOI: 10.1016/j.bmc.2015.06.007 BindingDB Entry DOI: 10.7270/Q2V126KK
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Mus musculus)	BDBM50108927 (CHEMBL3596952) Show SMILES Fc1ccc(c(F)c1)-c1ccc2oc(=O)n(-c3cc(F)ccc3F)c(=O)c2c1 |(7.73,-3.69,;6.67,-3.07,;6.66,-1.53,;5.33,-.77,;4,-1.54,;4,-3.08,;2.93,-3.7,;5.33,-3.85,;2.66,-.77,;2.66,.77,;1.33,1.54,;,.77,;-1.33,1.54,;-2.68,.77,;-3.75,1.39,;-2.68,-.77,;-4.01,-1.54,;-5.35,-.77,;-6.68,-1.54,;-7.75,-.92,;-6.68,-3.08,;-5.35,-3.85,;-4.01,-3.08,;-2.95,-3.7,;-1.33,-1.54,;-1.33,-2.77,;,-.77,;1.33,-1.54,)| Show InChI InChI=1S/C20H9F4NO3/c21-11-2-4-13(16(24)8-11)10-1-6-18-14(7-10)19(26)25(20(27)28-18)17-9-12(22)3-5-15(17)23/h1-9H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...				Bioorg Med Chem 23: 4522-32 (2015) Article DOI: 10.1016/j.bmc.2015.06.007 BindingDB Entry DOI: 10.7270/Q2V126KK
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50428824 (CHEMBL2336662) Show SMILES O=C1c2ccccc2C(=O)c2c1ccc1nc(CN3CCC(CCCC4CCNCC4)CC3)[nH]c21 Show InChI InChI=1S/C29H34N4O2/c34-28-21-6-1-2-7-22(21)29(35)26-23(28)8-9-24-27(26)32-25(31-24)18-33-16-12-20(13-17-33)5-3-4-19-10-14-30-15-11-19/h1-2,6-9,19-20,30H,3-5,10-18H2,(H,31,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Defense Medical Center Curated by ChEMBL					Assay Description Inhibition of TERT activity in human H1299 cells homogenates incubated for 5 mins by TRAP assay				Eur J Med Chem 60: 29-41 (2013) Article DOI: 10.1016/j.ejmech.2012.11.032 BindingDB Entry DOI: 10.7270/Q20P11DP
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50428822 (CHEMBL2336667) Show SMILES CCN1CCN(Cc2nc3ccc4C(=O)c5ccccc5C(=O)c4c3[nH]2)CC1 Show InChI InChI=1S/C22H22N4O2/c1-2-25-9-11-26(12-10-25)13-18-23-17-8-7-16-19(20(17)24-18)22(28)15-6-4-3-5-14(15)21(16)27/h3-8H,2,9-13H2,1H3,(H,23,24)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Defense Medical Center Curated by ChEMBL					Assay Description Inhibition of TERT activity in human H1299 cells homogenates incubated for 5 mins by TRAP assay				Eur J Med Chem 60: 29-41 (2013) Article DOI: 10.1016/j.ejmech.2012.11.032 BindingDB Entry DOI: 10.7270/Q20P11DP
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50428823 (CHEMBL2336666 | NSC-749235) Show SMILES CN1CCN(Cc2nc3ccc4C(=O)c5ccccc5C(=O)c4c3[nH]2)CC1 Show InChI InChI=1S/C21H20N4O2/c1-24-8-10-25(11-9-24)12-17-22-16-7-6-15-18(19(16)23-17)21(27)14-5-3-2-4-13(14)20(15)26/h2-7H,8-12H2,1H3,(H,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Defense Medical Center Curated by ChEMBL					Assay Description Inhibition of TERT activity in human H1299 cells homogenates incubated for 5 mins by TRAP assay				Eur J Med Chem 60: 29-41 (2013) Article DOI: 10.1016/j.ejmech.2012.11.032 BindingDB Entry DOI: 10.7270/Q20P11DP
					More data for this Ligand-Target Pair
Tumor necrosis factor ligand superfamily member 11 (Mus musculus)	BDBM50108930 (CHEMBL3335186) Show SMILES Fc1cc(Cl)ccc1-n1c(=O)oc2ccccc2c1=O |(22.73,-16.85,;22.73,-15.31,;24.06,-14.54,;24.05,-13,;25.38,-12.22,;22.71,-12.23,;21.38,-13.01,;21.4,-14.54,;20.07,-15.31,;20.07,-16.87,;21.4,-17.64,;18.74,-17.64,;17.4,-16.87,;16.07,-17.64,;14.73,-16.87,;14.74,-15.33,;16.06,-14.56,;17.4,-15.32,;18.73,-14.55,;18.73,-13.01,)| Show InChI InChI=1S/C14H7ClFNO3/c15-8-5-6-11(10(16)7-8)17-13(18)9-3-1-2-4-12(9)20-14(17)19/h1-7H	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Taipei Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant mouse RANKL-induced TRAP activity in mouse RAW264.7 cells using 4-nitrophenyl phosphate as TRAP substrate preincubated for ...				Bioorg Med Chem 23: 4522-32 (2015) Article DOI: 10.1016/j.bmc.2015.06.007 BindingDB Entry DOI: 10.7270/Q2V126KK
					More data for this Ligand-Target Pair