Compile Data Set for Download or QSAR

Found 65 hits with Last Name = 'lawson' and Initial = 'dm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50226181 ((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...) Show SMILES [#6]-[#8]-[#6@@H]1-[#6@@H](-[#8]-[#6](-[#7])=O)-[#6@@H](-[#8])-[#6@H](-[#8]-c2ccc3c(-[#8])c(-[#7]-[#6](=O)-c4ccc(-[#8])c(-[#6]\[#6]=[#6](/[#6])-[#6])c4)c(=O)oc3c2-[#6])-[#8]C1([#6])[#6] |r| Show InChI InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars		n/a	n/a	0.650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613099 (CHEMBL5288212) Show SMILES Cc1[nH]c(C(=O)Nc2nc3c(cc(cc3s2)C(O)=O)N2CCOCC2)c(Cl)c1Cl Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547859 (CHEMBL4752708) Show SMILES Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)C(O)=O)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613099 (CHEMBL5288212) Show SMILES Cc1[nH]c(C(=O)Nc2nc3c(cc(cc3s2)C(O)=O)N2CCOCC2)c(Cl)c1Cl Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547862 (CHEMBL4792402) Show SMILES CC(=O)Nc1ccc2nc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)sc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613104 (CHEMBL5268463) Show SMILES CC1CN(CC(C)O1)c1cc(cc2sc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)nc12)C(O)=O Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613099 (CHEMBL5288212) Show SMILES Cc1[nH]c(C(=O)Nc2nc3c(cc(cc3s2)C(O)=O)N2CCOCC2)c(Cl)c1Cl Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613103 (CHEMBL5269847) Show SMILES CC1CN(CCO1)c1cc(cc2sc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)nc12)C(O)=O Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613100 (CHEMBL5275604) Show SMILES CC1COCCN1c1cc(cc2sc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)nc12)C(O)=O Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613099 (CHEMBL5288212) Show SMILES Cc1[nH]c(C(=O)Nc2nc3c(cc(cc3s2)C(O)=O)N2CCOCC2)c(Cl)c1Cl Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613105 (CHEMBL5271811) Show SMILES [H][C@]12CC[C@]([H])(CN(C1)c1cc(cc3sc(NC(=O)c4[nH]c(C)c(Cl)c4Cl)nc13)C(O)=O)O2 |r| Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613107 (CHEMBL5267594) Show SMILES Cc1[nH]c(C(=O)Nc2nc3c(cc(cc3s2)C(O)=O)N2CCOC(C2)C(F)(F)F)c(Cl)c1Cl Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50568726 (CHEMBL4854181) Show SMILES Cc1[nH]c(C(=O)Nc2nc3c(OCc4ccccc4)cc(cc3s2)C(O)=O)c(Cl)c1Cl Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613106 (CHEMBL5276709) Show SMILES [H][C@]12CC[C@]([H])(COC1)N2c1cc(cc2sc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)nc12)C(O)=O |r| Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613101 (CHEMBL5282927) Show SMILES C[C@@H]1COCCN1c1cc(cc2sc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)nc12)C(O)=O |r| Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mus musculus (mouse))	BDBM50613102 (CHEMBL5285251) Show SMILES C[C@H]1COCCN1c1cc(cc2sc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)nc12)C(O)=O |r| Show InChI	MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli)	BDBM50521804 (CHEMBL4581035) Show SMILES CCNC(=O)Nc1cc(Nc2ccc(OC)cc2)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C21H22N6O3/c1-3-23-21(29)27-19-11-18(25-14-6-8-16(30-2)9-7-14)17(13-24-19)20(28)26-15-5-4-10-22-12-15/h4-13H,3H2,1-2H3,(H,26,28)(H3,23,24,25,27,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...				Bioorg Med Chem 27: 3546-3550 (2019) Article DOI: 10.1016/j.bmc.2019.06.015 BindingDB Entry DOI: 10.7270/Q2NK3JFZ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547863 (CHEMBL4747775) Show SMILES Cc1[nH]c(C(=O)Nc2nc3ccc(NC(N)=O)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547857 (CHEMBL4792173) Show SMILES Cc1[nH]c(C(=O)Nc2ccc3nc(NC(=O)C(O)=O)sc3c2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547866 (CHEMBL4786782) Show SMILES Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)CNC(=O)OC(C)(C)C)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli)	BDBM50521806 (CHEMBL4449908) Show SMILES CCNC(=O)Nc1cc(c(cn1)C(=O)Nc1cccnc1)-n1cc(Br)cn1 Show InChI InChI=1S/C17H16BrN7O2/c1-2-20-17(27)24-15-6-14(25-10-11(18)7-22-25)13(9-21-15)16(26)23-12-4-3-5-19-8-12/h3-10H,2H2,1H3,(H,23,26)(H2,20,21,24,27)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...				Bioorg Med Chem 27: 3546-3550 (2019) Article DOI: 10.1016/j.bmc.2019.06.015 BindingDB Entry DOI: 10.7270/Q2NK3JFZ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50547859 (CHEMBL4752708) Show SMILES Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)C(O)=O)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50226181 ((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...) Show SMILES [#6]-[#8]-[#6@@H]1-[#6@@H](-[#8]-[#6](-[#7])=O)-[#6@@H](-[#8])-[#6@H](-[#8]-c2ccc3c(-[#8])c(-[#7]-[#6](=O)-c4ccc(-[#8])c(-[#6]\[#6]=[#6](/[#6])-[#6])c4)c(=O)oc3c2-[#6])-[#8]C1([#6])[#6] |r| Show InChI InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547858 (CHEMBL4755085) Show SMILES CCOC(=O)C(=O)Nc1ccc2nc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)sc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50198240 (CHEMBL3908487) Show SMILES OC(=O)C(=O)Nc1ccc2nc(NC(=O)c3cc(Br)c(Br)[nH]3)sc2c1 Show InChI InChI=1S/C14H8Br2N4O4S/c15-6-4-8(18-10(6)16)11(21)20-14-19-7-2-1-5(3-9(7)25-14)17-12(22)13(23)24/h1-4,18H,(H,17,22)(H,23,24)(H,19,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547860 (CHEMBL4763466) Show SMILES CC(=O)Nc1nc2ccc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)cc2s1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli)	BDBM50521803 (CHEMBL4568624) Show SMILES CCNC(=O)Nc1cc(c(cn1)C(=O)Nc1cccnc1)-n1cncn1 Show InChI InChI=1S/C16H16N8O2/c1-2-19-16(26)23-14-6-13(24-10-18-9-21-24)12(8-20-14)15(25)22-11-4-3-5-17-7-11/h3-10H,2H2,1H3,(H,22,25)(H2,19,20,23,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...				Bioorg Med Chem 27: 3546-3550 (2019) Article DOI: 10.1016/j.bmc.2019.06.015 BindingDB Entry DOI: 10.7270/Q2NK3JFZ
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli)	BDBM50521799 (CHEMBL4459270) Show SMILES CCNC(=O)Nc1cc(c(cn1)C(=O)Nc1cccnc1)-n1cccn1 Show InChI InChI=1S/C17H17N7O2/c1-2-19-17(26)23-15-9-14(24-8-4-7-21-24)13(11-20-15)16(25)22-12-5-3-6-18-10-12/h3-11H,2H2,1H3,(H,22,25)(H2,19,20,23,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...				Bioorg Med Chem 27: 3546-3550 (2019) Article DOI: 10.1016/j.bmc.2019.06.015 BindingDB Entry DOI: 10.7270/Q2NK3JFZ
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli)	BDBM50521800 (CHEMBL4470688) Show SMILES CCNC(=O)Nc1cc(N2CCC(N)C2)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C18H23N7O2/c1-2-21-18(27)24-16-8-15(25-7-5-12(19)11-25)14(10-22-16)17(26)23-13-4-3-6-20-9-13/h3-4,6,8-10,12H,2,5,7,11,19H2,1H3,(H,23,26)(H2,21,22,24,27)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...				Bioorg Med Chem 27: 3546-3550 (2019) Article DOI: 10.1016/j.bmc.2019.06.015 BindingDB Entry DOI: 10.7270/Q2NK3JFZ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547865 (CHEMBL4741205) Show SMILES Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)CCNC(=O)OC(C)(C)C)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547867 (CHEMBL4793192) Show SMILES Cl.Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)CCN)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli)	BDBM50521805 (CHEMBL4436644) Show SMILES CCNC(=O)Nc1cc(N2CCCC2)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C18H22N6O2/c1-2-20-18(26)23-16-10-15(24-8-3-4-9-24)14(12-21-16)17(25)22-13-6-5-7-19-11-13/h5-7,10-12H,2-4,8-9H2,1H3,(H,22,25)(H2,20,21,23,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...				Bioorg Med Chem 27: 3546-3550 (2019) Article DOI: 10.1016/j.bmc.2019.06.015 BindingDB Entry DOI: 10.7270/Q2NK3JFZ
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli)	BDBM50521801 (CHEMBL4521306) Show SMILES CCNC(=O)Nc1cc(c(cn1)C(=O)Nc1cccnc1)-n1nccn1 Show InChI InChI=1S/C16H16N8O2/c1-2-18-16(26)23-14-8-13(24-20-6-7-21-24)12(10-19-14)15(25)22-11-4-3-5-17-9-11/h3-10H,2H2,1H3,(H,22,25)(H2,18,19,23,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...				Bioorg Med Chem 27: 3546-3550 (2019) Article DOI: 10.1016/j.bmc.2019.06.015 BindingDB Entry DOI: 10.7270/Q2NK3JFZ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50226181 ((3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-...) Show SMILES [#6]-[#8]-[#6@@H]1-[#6@@H](-[#8]-[#6](-[#7])=O)-[#6@@H](-[#8])-[#6@H](-[#8]-c2ccc3c(-[#8])c(-[#7]-[#6](=O)-c4ccc(-[#8])c(-[#6]\[#6]=[#6](/[#6])-[#6])c4)c(=O)oc3c2-[#6])-[#8]C1([#6])[#6] |r| Show InChI InChI=1S/C31H36N2O11/c1-14(2)7-8-16-13-17(9-11-19(16)34)27(37)33-21-22(35)18-10-12-20(15(3)24(18)42-28(21)38)41-29-23(36)25(43-30(32)39)26(40-6)31(4,5)44-29/h7,9-13,23,25-26,29,34-36H,8H2,1-6H3,(H2,32,39)(H,33,37)/t23-,25+,26-,29-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	MMDB Article PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547856 (CHEMBL4789518) Show SMILES COC(=O)CC(=O)Nc1nc2ccc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)cc2s1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli)	BDBM50521802 (CHEMBL4465300) Show SMILES CCNC(=O)Nc1cc(c(cn1)C(=O)Nc1cccnc1)-n1ccnn1 Show InChI InChI=1S/C16H16N8O2/c1-2-18-16(26)22-14-8-13(24-7-6-20-23-24)12(10-19-14)15(25)21-11-4-3-5-17-9-11/h3-10H,2H2,1H3,(H,21,25)(H2,18,19,22,26)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...				Bioorg Med Chem 27: 3546-3550 (2019) Article DOI: 10.1016/j.bmc.2019.06.015 BindingDB Entry DOI: 10.7270/Q2NK3JFZ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50547857 (CHEMBL4792173) Show SMILES Cc1[nH]c(C(=O)Nc2ccc3nc(NC(=O)C(O)=O)sc3c2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50547866 (CHEMBL4786782) Show SMILES Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)CNC(=O)OC(C)(C)C)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547868 (CHEMBL4781272) Show SMILES Cl.Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)CN)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A/B (Staphylococcus aureus)	BDBM50547867 (CHEMBL4793192) Show SMILES Cl.Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)CCN)cc3s2)c(Cl)c1Cl Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A/B (Staphylococcus aureus)	BDBM50547859 (CHEMBL4752708) Show SMILES Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)C(O)=O)cc3s2)c(Cl)c1Cl Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547855 (CHEMBL4746092) Show SMILES CCOC(=O)C(=O)Nc1nc2ccc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)cc2s1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50547868 (CHEMBL4781272) Show SMILES Cl.Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)CN)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50547862 (CHEMBL4792402) Show SMILES CC(=O)Nc1ccc2nc(NC(=O)c3[nH]c(C)c(Cl)c3Cl)sc2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A (Escherichia coli)	BDBM50521807 (CHEMBL4577939) Show SMILES CCNC(=O)Nc1cc(Nc2ccccc2O)c(cn1)C(=O)Nc1cccnc1 Show InChI InChI=1S/C20H20N6O3/c1-2-22-20(29)26-18-10-16(25-15-7-3-4-8-17(15)27)14(12-23-18)19(28)24-13-6-5-9-21-11-13/h3-12,27H,2H2,1H3,(H,24,28)(H3,22,23,25,26,29)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
University of Leeds Curated by ChEMBL					Assay Description Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...				Bioorg Med Chem 27: 3546-3550 (2019) Article DOI: 10.1016/j.bmc.2019.06.015 BindingDB Entry DOI: 10.7270/Q2NK3JFZ
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50547853 (CHEMBL4763407) Show SMILES OC(=O)C(=O)Nc1ccc2nc(NC(=O)c3cc(Br)c(Br)[nH]3)[nH]c2c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50547865 (CHEMBL4741205) Show SMILES Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)CCNC(=O)OC(C)(C)C)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	780	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA topoisomerase 4 subunit A/B (Staphylococcus aureus)	BDBM50547857 (CHEMBL4792173) Show SMILES Cc1[nH]c(C(=O)Nc2ccc3nc(NC(=O)C(O)=O)sc3c2)c(Cl)c1Cl Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50547863 (CHEMBL4747775) Show SMILES Cc1[nH]c(C(=O)Nc2nc3ccc(NC(N)=O)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50547867 (CHEMBL4793192) Show SMILES Cl.Cc1[nH]c(C(=O)Nc2nc3ccc(NC(=O)CCN)cc3s2)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 65 total )  |  Next  |  Last  >>

Jump to: