Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50030474 (Avandamet | Avandaryl | Avandia | BRL-49653 | CHEB...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars | DrugBank PDB Article PubMed | n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human N-terminal GAL4-DBD fused PPARgamma LBD expressed in reporter cells measured after 24 hrs by luciferase reporter... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50271610 (CHEMBL418695) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.94E+3 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human N-terminal GAL4-DBD fused PPARgamma LBD expressed in reporter cells measured after 24 hrs by luciferase reporter... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50271611 (CHEMBL4125720) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.51E+3 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human N-terminal GAL4-DBD fused PPARgamma LBD expressed in reporter cells measured after 24 hrs by luciferase reporter... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50271612 (CHEMBL4127761) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human N-terminal GAL4-DBD fused PPARgamma LBD expressed in reporter cells measured after 24 hrs by luciferase reporter... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50271613 (CHEMBL4127972) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.13E+4 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50271616 (CHEMBL4127920) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50271615 (CHEMBL4130213) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.13E+4 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50271610 (CHEMBL418695) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50271611 (CHEMBL4125720) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.06E+3 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50271612 (CHEMBL4127761) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 4.31E+3 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Free fatty acid receptor 1 (Homo sapiens (Human)) | BDBM50271614 (CHEMBL4126802) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.78E+4 | n/a | n/a | n/a | n/a |
Suez Canal University Curated by ChEMBL | Assay Description Transactivation of recombinant human FFAR1 expressed in CHOK1 cells co-expressing Galpha15 assessed as increase in calcium flux measured after 20 sec... | Bioorg Med Chem Lett 28: 1595-1602 (2018) Article DOI: 10.1016/j.bmcl.2018.03.051 BindingDB Entry DOI: 10.7270/Q2N58PVR | |||||||||||
More data for this Ligand-Target Pair |