Compile Data Set for Download or QSAR

Found 25 hits with Last Name = 'prochownik' and Initial = 'ev'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50479535 (CAS 160693-53-8 | CHEMBL491274) Show SMILES CCc1ccc(cc1)N1CC(CC1=O)C(=O)OC Show InChI InChI=1S/C14H17NO3/c1-3-10-4-6-12(7-5-10)15-9-11(8-13(15)16)14(17)18-2/h4-7,11H,3,8-9H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	<5.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of CYP3A4				J Med Chem 52: 1247-50 (2009) Article DOI: 10.1021/jm801278g BindingDB Entry DOI: 10.7270/Q23T9M14
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50479542 (CAS 31122-64-2 | CHEMBL491273) Show SMILES O=C(CCN1C(=O)c2ccccc2C1=O)N1CCCCC1 Show InChI InChI=1S/C16H18N2O3/c19-14(17-9-4-1-5-10-17)8-11-18-15(20)12-6-2-3-7-13(12)16(18)21/h2-3,6-7H,1,4-5,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	<5.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of CYP3A4				J Med Chem 52: 1247-50 (2009) Article DOI: 10.1021/jm801278g BindingDB Entry DOI: 10.7270/Q23T9M14
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50479541 (CAS 303796-42-1 | CHEMBL446965) Show SMILES CCc1ccc(OCC(=O)NCCc2ccccc2)cc1 Show InChI InChI=1S/C18H21NO2/c1-2-15-8-10-17(11-9-15)21-14-18(20)19-13-12-16-6-4-3-5-7-16/h3-11H,2,12-14H2,1H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	<5.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of CYP3A4				J Med Chem 52: 1247-50 (2009) Article DOI: 10.1021/jm801278g BindingDB Entry DOI: 10.7270/Q23T9M14
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50479540 (CAS 329920-60-7 | CHEMBL452613) Show SMILES CCc1ccc(OCC(=O)NCc2cccc3ccccc23)cc1 Show InChI InChI=1S/C21H21NO2/c1-2-16-10-12-19(13-11-16)24-15-21(23)22-14-18-8-5-7-17-6-3-4-9-20(17)18/h3-13H,2,14-15H2,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	<5.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of CYP3A4				J Med Chem 52: 1247-50 (2009) Article DOI: 10.1021/jm801278g BindingDB Entry DOI: 10.7270/Q23T9M14
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50479539 (CAS 307545-04-6 | CHEMBL491275) Show SMILES CC(C)c1ccc(OCC(=O)Nc2nc3ccccc3s2)cc1 Show InChI InChI=1S/C18H18N2O2S/c1-12(2)13-7-9-14(10-8-13)22-11-17(21)20-18-19-15-5-3-4-6-16(15)23-18/h3-10,12H,11H2,1-2H3,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	<5.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of CYP3A4				J Med Chem 52: 1247-50 (2009) Article DOI: 10.1021/jm801278g BindingDB Entry DOI: 10.7270/Q23T9M14
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50479536 (CHEMBL489096) Show SMILES CCc1ccc(OCC(=O)Nc2ccc(C)cc2Br)cc1 Show InChI InChI=1S/C17H18BrNO2/c1-3-13-5-7-14(8-6-13)21-11-17(20)19-16-9-4-12(2)10-15(16)18/h4-10H,3,11H2,1-2H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	<5.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of CYP3A4				J Med Chem 52: 1247-50 (2009) Article DOI: 10.1021/jm801278g BindingDB Entry DOI: 10.7270/Q23T9M14
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50479537 (CHEMBL504747) Show SMILES Cc1ccc(C)c(OCN2Cc3ccccc3C2C=O)c1 Show InChI InChI=1S/C18H19NO2/c1-13-7-8-14(2)18(9-13)21-12-19-10-15-5-3-4-6-16(15)17(19)11-20/h3-9,11,17H,10,12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<5.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of CYP3A4				J Med Chem 52: 1247-50 (2009) Article DOI: 10.1021/jm801278g BindingDB Entry DOI: 10.7270/Q23T9M14
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50479538 (CAS 381679-98-5 | CHEMBL490678) Show SMILES CCc1ccc(CCNS(=O)(=O)c2ccc(SC)cc2)cc1 Show InChI InChI=1S/C17H21NO2S2/c1-3-14-4-6-15(7-5-14)12-13-18-22(19,20)17-10-8-16(21-2)9-11-17/h4-11,18H,3,12-13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<5.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pittsburgh Curated by ChEMBL					Assay Description Inhibition of CYP3A4				J Med Chem 52: 1247-50 (2009) Article DOI: 10.1021/jm801278g BindingDB Entry DOI: 10.7270/Q23T9M14
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498221 (CHEMBL3427016) Show SMILES CCOC(=O)C(=O)Nc1ccc(cc1OCC(C)C)C(=O)Nc1ccc(cc1OCC(C)C)C(O)=O Show InChI InChI=1S/C26H32N2O8/c1-6-34-26(33)24(30)28-20-9-7-17(11-21(20)35-13-15(2)3)23(29)27-19-10-8-18(25(31)32)12-22(19)36-14-16(4)5/h7-12,15-16H,6,13-14H2,1-5H3,(H,27,29)(H,28,30)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant c-Myc-Max/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative to ...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498222 (CHEMBL3427045) Show SMILES CC(C)COc1cc(ccc1NC(=O)c1ccc(c(OCc2cccc3ccccc23)c1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C29H26N2O7/c1-18(2)16-37-26-15-21(29(33)34)10-12-24(26)30-28(32)20-11-13-25(31(35)36)27(14-20)38-17-22-8-5-7-19-6-3-4-9-23(19)22/h3-15,18H,16-17H2,1-2H3,(H,30,32)(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant c-Myc-Max/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative to ...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498221 (CHEMBL3427016) Show SMILES CCOC(=O)C(=O)Nc1ccc(cc1OCC(C)C)C(=O)Nc1ccc(cc1OCC(C)C)C(O)=O Show InChI InChI=1S/C26H32N2O8/c1-6-34-26(33)24(30)28-20-9-7-17(11-21(20)35-13-15(2)3)23(29)27-19-10-8-18(25(31)32)12-22(19)36-14-16(4)5/h7-12,15-16H,6,13-14H2,1-5H3,(H,27,29)(H,28,30)(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant Myc(L)-Max(L)/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498222 (CHEMBL3427045) Show SMILES CC(C)COc1cc(ccc1NC(=O)c1ccc(c(OCc2cccc3ccccc23)c1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C29H26N2O7/c1-18(2)16-37-26-15-21(29(33)34)10-12-24(26)30-28(32)20-11-13-25(31(35)36)27(14-20)38-17-22-8-5-7-19-6-3-4-9-23(19)22/h3-15,18H,16-17H2,1-2H3,(H,30,32)(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant Myc(L)-Max(L)/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498219 (CHEMBL3427047) Show SMILES CC(C)COc1cc(ccc1NC(=O)c1ccc(c(OCC(C)C)c1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C22H26N2O7/c1-13(2)11-30-19-10-16(22(26)27)5-7-17(19)23-21(25)15-6-8-18(24(28)29)20(9-15)31-12-14(3)4/h5-10,13-14H,11-12H2,1-4H3,(H,23,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant c-Myc-Max/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative to ...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498217 (CHEMBL3427021) Show SMILES CC(C)COc1nc(ccc1NC(=O)c1ccc(c(OCC(C)C)n1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C20H24N4O7/c1-11(2)9-30-18-14(5-6-15(23-18)20(26)27)21-17(25)13-7-8-16(24(28)29)19(22-13)31-10-12(3)4/h5-8,11-12H,9-10H2,1-4H3,(H,21,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant c-Myc-Max/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative to ...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein (Homo sapiens (Human))	BDBM93880 (4-(7-Nitro-benzo[1,2,5]oxadiazol-4-ylamino)-benzoi...) Show SMILES OC(=O)c1ccc(Nc2ccc([N+]([O-])=O)c3nonc23)cc1 Show InChI InChI=1S/C13H8N4O5/c18-13(19)7-1-3-8(4-2-7)14-9-5-6-10(17(20)21)12-11(9)15-22-16-12/h1-6,14H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) (unknown origin) assessed as disruption of Myc-Max dimer...				Bioorg Med Chem Lett 23: 370-4 (2012) Article DOI: 10.1016/j.bmcl.2012.10.013 BindingDB Entry DOI: 10.7270/Q2WM1FPM
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498218 (CHEMBL3427054) Show SMILES CC(C)COc1cc(ccc1NC(=O)c1ccc(c(OCc2ccccc2)c1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C25H24N2O7/c1-16(2)14-33-22-13-19(25(29)30)8-10-20(22)26-24(28)18-9-11-21(27(31)32)23(12-18)34-15-17-6-4-3-5-7-17/h3-13,16H,14-15H2,1-2H3,(H,26,28)(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant c-Myc-Max/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative to ...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498220 (CHEMBL3427022) Show SMILES CC(C)COc1cc(ccc1NC(=O)c1ccc(c(OCC(C)C)n1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C21H25N3O7/c1-12(2)10-30-18-9-14(21(26)27)5-6-15(18)22-19(25)16-7-8-17(24(28)29)20(23-16)31-11-13(3)4/h5-9,12-13H,10-11H2,1-4H3,(H,22,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant c-Myc-Max/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative to ...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498217 (CHEMBL3427021) Show SMILES CC(C)COc1nc(ccc1NC(=O)c1ccc(c(OCC(C)C)n1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C20H24N4O7/c1-11(2)9-30-18-14(5-6-15(23-18)20(26)27)21-17(25)13-7-8-16(24(28)29)19(22-13)31-10-12(3)4/h5-8,11-12H,9-10H2,1-4H3,(H,21,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant Myc(L)-Max(L)/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498218 (CHEMBL3427054) Show SMILES CC(C)COc1cc(ccc1NC(=O)c1ccc(c(OCc2ccccc2)c1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C25H24N2O7/c1-16(2)14-33-22-13-19(25(29)30)8-10-20(22)26-24(28)18-9-11-21(27(31)32)23(12-18)34-15-17-6-4-3-5-7-17/h3-13,16H,14-15H2,1-2H3,(H,26,28)(H,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant Myc(L)-Max(L)/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498219 (CHEMBL3427047) Show SMILES CC(C)COc1cc(ccc1NC(=O)c1ccc(c(OCC(C)C)c1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C22H26N2O7/c1-13(2)11-30-19-10-16(22(26)27)5-7-17(19)23-21(25)15-6-8-18(24(28)29)20(9-15)31-12-14(3)4/h5-10,13-14H,11-12H2,1-4H3,(H,23,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant Myc(L)-Max(L)/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Protein max (Homo sapiens (Human))	BDBM93880 (4-(7-Nitro-benzo[1,2,5]oxadiazol-4-ylamino)-benzoi...) Show SMILES OC(=O)c1ccc(Nc2ccc([N+]([O-])=O)c3nonc23)cc1 Show InChI InChI=1S/C13H8N4O5/c18-13(19)7-1-3-8(4-2-7)14-9-5-6-10(17(20)21)12-11(9)15-22-16-12/h1-6,14H,(H,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibition of His6-tagged Max (151 amino acid residues) (unknown origin) assessed as disruption of Max-Max dimerization by electrophoretic mobility s...				Bioorg Med Chem Lett 23: 370-4 (2012) Article DOI: 10.1016/j.bmcl.2012.10.013 BindingDB Entry DOI: 10.7270/Q2WM1FPM
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498220 (CHEMBL3427022) Show SMILES CC(C)COc1cc(ccc1NC(=O)c1ccc(c(OCC(C)C)n1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C21H25N3O7/c1-12(2)10-30-18-9-14(21(26)27)5-6-15(18)22-19(25)16-7-8-17(24(28)29)20(23-16)31-11-13(3)4/h5-9,12-13H,10-11H2,1-4H3,(H,22,25)(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Disruption of human recombinant Myc(L)-Max(L)/DNA (unknown origin) binding assessed as complex level by electrophoretic mobility shift assay relative...				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair
Myc proto-oncogene protein (Homo sapiens (Human))	BDBM50423921 (CHEMBL2312756) Show SMILES [O-][N+](=O)c1ccc(Nc2ccccc2-c2ccccc2)c2nonc12 Show InChI InChI=1S/C18H12N4O3/c23-22(24)16-11-10-15(17-18(16)21-25-20-17)19-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-11,19H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.46E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Inhibition of recombinant His6-tagged c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) (unknown origin) assessed as disruption of Myc-Max dimer...				Bioorg Med Chem Lett 23: 370-4 (2012) Article DOI: 10.1016/j.bmcl.2012.10.013 BindingDB Entry DOI: 10.7270/Q2WM1FPM
					More data for this Ligand-Target Pair
Myc proto-oncogene protein (Homo sapiens (Human))	BDBM50423921 (CHEMBL2312756) Show SMILES [O-][N+](=O)c1ccc(Nc2ccccc2-c2ccccc2)c2nonc12 Show InChI InChI=1S/C18H12N4O3/c23-22(24)16-11-10-15(17-18(16)21-25-20-17)19-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-11,19H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to human c-Myc bHLH-ZIP domain (353 to 437 amino acid residues) expressed in Escherichia coli BL21 (DE3) by fluorescence polarizatio...				Bioorg Med Chem Lett 23: 370-4 (2012) Article DOI: 10.1016/j.bmcl.2012.10.013 BindingDB Entry DOI: 10.7270/Q2WM1FPM
					More data for this Ligand-Target Pair
Myc proto-oncogene protein/Protein max (Homo sapiens (Human))	BDBM50498222 (CHEMBL3427045) Show SMILES CC(C)COc1cc(ccc1NC(=O)c1ccc(c(OCc2cccc3ccccc23)c1)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C29H26N2O7/c1-18(2)16-37-26-15-21(29(33)34)10-12-24(26)30-28(32)20-11-13-25(31(35)36)27(14-20)38-17-22-8-5-7-19-6-3-4-9-23(19)22/h3-15,18H,16-17H2,1-2H3,(H,30,32)(H,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Binding affinity to human recombinant 15N labeled c-Myc-Max(S) heterodimer assessed as chemical shift up to 100 uM by NMR spectroscopy				J Med Chem 58: 3002-24 (2015) Article DOI: 10.1021/jm501440q BindingDB Entry DOI: 10.7270/Q2W3809S
					More data for this Ligand-Target Pair