BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 127 hits with Last Name = 'gaggia' and Initial = 'f'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))		BDBM17292
PNG
((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]
Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 0.330n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor


(Homo sapiens (Human))		BDBM17292
PNG
((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]
Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 0.330n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor


(Homo sapiens (Human))		BDBM50551587
PNG
(CHEMBL4761289)
Show SMILES [#8]-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-[#6]-[#6]-[#6]-1)\c1ccc(\[#6]=[#6]\[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)\[#6]=[#6]\c2ccc(cc2)-[#6](=[#6]-2\[#6]-[#6]-[#6]-[#6]-[#6]-2)\c2ccc(-[#8])cc2)cc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.420n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586400
PNG
(CHEMBL5086315)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCNC(=O)CCCCCCCn2c(=S)[nH]c3ccccc3c2=O)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.820n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50551582
PNG
(CHEMBL279301 | E-4-Hydroxytamoxifen)
Show SMILES CC\C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.990n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 h...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM17292
PNG
((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]
Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 1n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor beta


(Homo sapiens (Human))		BDBM20608
PNG
(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Show SMILES CC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 1n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase ...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor beta


(Homo sapiens (Human))		BDBM17292
PNG
((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3CC[C@@]21[H]
Show InChI InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 1n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor


(Homo sapiens (Human))		BDBM50586411
PNG
(CHEMBL5076984)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCCNC(=O)CCc2nc3cc(O)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.30n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50551590
PNG
(CHEMBL4758245)
Show SMILES CC\C(=C(\c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCNC(=O)\C=C\c2ccc(cc2)C(=C(/CC)c2ccccc2)\c2ccc(O)cc2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.30n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586400
PNG
(CHEMBL5086315)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCNC(=O)CCCCCCCn2c(=S)[nH]c3ccccc3c2=O)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.40n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586408
PNG
(CHEMBL5087008)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCNC(=O)CCc2nc3cc(O)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.5n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586410
PNG
(CHEMBL5092334)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCNC(=O)CCc2nc3cc(O)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586406
PNG
(CHEMBL5092721)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCCNC(=O)CCc2nc3ccc(OC)cc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.60n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50551582
PNG
(CHEMBL279301 | E-4-Hydroxytamoxifen)
Show SMILES CC\C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.70n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM20608
PNG
(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Show SMILES CC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 1.70n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor


(Homo sapiens (Human))		BDBM50551589
PNG
(CHEMBL4790840)
Show SMILES [#8]-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-[#6]-[#6]-[#6]-1)\c1ccc(\[#6]=[#6]\[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#7]-[#6](=O)\[#6]=[#6]\c2ccc(cc2)-[#6](=[#6]-2/[#6]-[#6]-[#6]-[#6]-[#6]-2)\c2ccc(-[#8])cc2)cc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.70n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586408
PNG
(CHEMBL5087008)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCNC(=O)CCc2nc3cc(O)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586405
PNG
(CHEMBL5075366)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCNC(=O)CCc2nc3cc(OC)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50551582
PNG
(CHEMBL279301 | E-4-Hydroxytamoxifen)
Show SMILES CC\C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM20608
PNG
(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Show SMILES CC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 2.20n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor


(Homo sapiens (Human))		BDBM50551582
PNG
(CHEMBL279301 | E-4-Hydroxytamoxifen)
Show SMILES CC\C(=C(\c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.30n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 ...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM20608
PNG
(4-Hydroxytamoxifen | 4-Hydroxytamoxifen (9) | 4-[(...)
Show SMILES CC\C(=C(/c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C26H29NO2/c1-4-25(20-8-6-5-7-9-20)26(21-10-14-23(28)15-11-21)22-12-16-24(17-13-22)29-19-18-27(2)3/h5-17,28H,4,18-19H2,1-3H3/b26-25-
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents

Similars
PDB
Article
PubMed
n/an/a 2.30n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor


(Homo sapiens (Human))		BDBM50551585
PNG
(CHEMBL4790191)
Show SMILES [#8]-c1ccc(cc1)-[#6](=[#6]-1\[#6]-[#6]-[#6]-[#6]-[#6]-1)\c1ccc(\[#6]=[#6]\[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)\[#6]=[#6]\c2ccc(cc2)-[#6](=[#6]-2/[#6]-[#6]-[#6]-[#6]-[#6]-2)\c2ccc(-[#8])cc2)cc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.40n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586407
PNG
(CHEMBL5091421)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCCCNC(=O)CCc2nc3cc(OC)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.60n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586409
PNG
(CHEMBL5088360)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCNC(=O)CCc2nc3cc(O)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586403
PNG
(CHEMBL5085956)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCNC(=O)CCc2nc3cc(OC)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.80n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586410
PNG
(CHEMBL5092334)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCNC(=O)CCc2nc3cc(O)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.80n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50238741
PNG
(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3C[C@@H](CCCCCCCCC[S+]([O-])CCCC(F)(F)C(F)(F)F)[C@@]21[H]
Show InChI InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.90n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50238741
PNG
(CHEBI:31638 | Faslodex | Fulvestrant | ICI-182780 ...)
Show SMILES [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])c3ccc(O)cc3C[C@@H](CCCCCCCCC[S+]([O-])CCCC(F)(F)C(F)(F)F)[C@@]21[H]
Show InChI InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.90n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586404
PNG
(CHEMBL5071793)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCNC(=O)CCc2nc3ccc(OC)cc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586412
PNG
(CHEMBL5094540)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCCCNC(=O)CCc2nc3cc(O)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.40n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50551586
PNG
(CHEMBL4755319)
Show SMILES CC\C(=C(\c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCCNC(=O)\C=C\c2ccc(cc2)C(=C(/CC)c2ccccc2)\c2ccc(O)cc2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.5n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERalpha by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586413
PNG
(CHEMBL5094545)
Show SMILES OC(=O)C(F)(F)F.CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCN)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.60n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase ...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50551584
PNG
(CHEMBL4793264)
Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC\C(=C(\c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCN)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.60n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 h...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50084948
PNG
(CHEMBL195515 | GW7604)
Show SMILES CC\C(=C(/c1ccc(O)cc1)c1ccc(\C=C\C(O)=O)cc1)c1ccccc1
Show InChI InChI=1S/C25H22O3/c1-2-23(19-6-4-3-5-7-19)25(21-13-15-22(26)16-14-21)20-11-8-18(9-12-20)10-17-24(27)28/h3-17,26H,2H2,1H3,(H,27,28)/b17-10+,25-23+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.80n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50238736
PNG
(CHEMBL1091535 | GW7604)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(O)=O)cc1)c1ccccc1
Show InChI InChI=1S/C25H22O3/c1-2-23(19-6-4-3-5-7-19)25(21-13-15-22(26)16-14-21)20-11-8-18(9-12-20)10-17-24(27)28/h3-17,26H,2H2,1H3,(H,27,28)/b17-10+,25-23+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 3.80n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586411
PNG
(CHEMBL5076984)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCCNC(=O)CCc2nc3cc(O)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.80n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586409
PNG
(CHEMBL5088360)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCNC(=O)CCc2nc3cc(O)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.80n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586399
PNG
(CHEMBL5094443)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCNC(=O)CCCn2c(=S)[nH]c3ccccc3c2=O)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586399
PNG
(CHEMBL5094443)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCNC(=O)CCCn2c(=S)[nH]c3ccccc3c2=O)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.10n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase ...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586404
PNG
(CHEMBL5071793)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCNC(=O)CCc2nc3ccc(OC)cc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.10n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586402
PNG
(CHEMBL5083251)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCNC(=O)c2ccc(cc2)N2CCN(CC2)C(=O)CCCCCCCn2c(=S)[nH]c3ccccc3c2=O)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.20n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50551584
PNG
(CHEMBL4793264)
Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC\C(=C(\c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCN)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.30n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labelled E2 from recombinant human GST-tagged ERbeta by LanthaScreen TR-FRET assay

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586401
PNG
(CHEMBL5094584)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCNC(=O)c2ccc(cc2)N2CCN(CC2)C(=O)CCCn2c(=S)[nH]c3ccccc3c2=O)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.60n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERalpha (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586403
PNG
(CHEMBL5085956)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCNC(=O)CCc2nc3cc(OC)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.90n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586407
PNG
(CHEMBL5091421)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCCCNC(=O)CCc2nc3cc(OC)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.20n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50586405
PNG
(CHEMBL5075366)
Show SMILES CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCCCNC(=O)CCc2nc3cc(OC)ccc3[nH]2)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.30n/an/an/an/an/an/a


TBA

Assay Description
Displacement of fluorescent-labeled E2 from LBD of ERbeta (unknown origin) by TR-FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50586413
PNG
(CHEMBL5094545)
Show SMILES OC(=O)C(F)(F)F.CCC(=C(c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCN)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.30n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation by dual luciferase...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.0c02230
BindingDB Entry DOI: 10.7270/Q26H4N92
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50551584
PNG
(CHEMBL4793264)
Show SMILES OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CC\C(=C(\c1ccc(O)cc1)c1ccc(\C=C\C(=O)NCCN)cc1)c1ccccc1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.30n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at ERalpha (unknown origin) expressed in human U2OS cells assessed as inhibition of E2-induced transactivation measured after 21 ...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112191
BindingDB Entry DOI: 10.7270/Q22R3W9R
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 127 total )  |  Next  |  Last  >>
Jump to: