Found 149 hits with Last Name = 'suo' and Initial = 'fz' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM256459
(US10329256, Example 3 | US9487512, 3 | US9944601, ...)Show InChI InChI=1S/C14H20N2/c1-2-4-11(5-3-1)13-10-14(13)16-12-6-8-15-9-7-12/h1-5,12-16H,6-10H2/t13-,14+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ... |
Eur J Med Chem 175: 357-372 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.065
BindingDB Entry DOI: 10.7270/Q2X351W0 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50445346
(CHEMBL3104250)Show SMILES CC(=NNC(=O)c1cccc(c1)S(=O)(=O)N1CCOCC1)c1cc(Cl)ccc1O |w:2.2| Show InChI InChI=1S/C19H20ClN3O5S/c1-13(17-12-15(20)5-6-18(17)24)21-22-19(25)14-3-2-4-16(11-14)29(26,27)23-7-9-28-10-8-23/h2-6,11-12,24H,7-10H2,1H3,(H,22,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay |
Eur J Med Chem 166: 432-444 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.075
BindingDB Entry DOI: 10.7270/Q29S1VGB |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451592
(CHEMBL4212776)Show SMILES Oc1ccc(Cl)cc1\C=N\NC(=O)c1cccc(c1)S(=O)(=O)N1CCOCC1 Show InChI InChI=1S/C18H18ClN3O5S/c19-15-4-5-17(23)14(10-15)12-20-21-18(24)13-2-1-3-16(11-13)28(25,26)22-6-8-27-9-7-22/h1-5,10-12,23H,6-9H2,(H,21,24)/b20-12+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50158869
(CHEMBL3786182 | US10836743, Compound GSK-2879552 |...)Show SMILES OC(=O)c1ccc(CN2CCC(CN[C@@H]3C[C@H]3c3ccccc3)CC2)cc1 |r| Show InChI InChI=1S/C23H28N2O2/c26-23(27)20-8-6-18(7-9-20)16-25-12-10-17(11-13-25)15-24-22-14-21(22)19-4-2-1-3-5-19/h1-9,17,21-22,24H,10-16H2,(H,26,27)/t21-,22+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay |
ACS Med Chem Lett 8: 384-389 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00423
BindingDB Entry DOI: 10.7270/Q2FQ9ZV3 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451589
(CHEMBL4204049)Show SMILES CCN(CC)c1ccc(\C=N\NC(=O)CN[C@@H]2C[C@H]2c2ccc(F)c(F)c2)c(O)c1 |r| Show InChI InChI=1S/C22H26F2N4O2/c1-3-28(4-2)16-7-5-15(21(29)10-16)12-26-27-22(30)13-25-20-11-17(20)14-6-8-18(23)19(24)9-14/h5-10,12,17,20,25,29H,3-4,11,13H2,1-2H3,(H,27,30)/b26-12+/t17-,20+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451591
(CHEMBL4208387)Show SMILES CCOc1cccc(\C=N\NC(=O)CN[C@@H]2C[C@H]2c2ccc(F)c(F)c2)c1O |r| Show InChI InChI=1S/C20H21F2N3O3/c1-2-28-18-5-3-4-13(20(18)27)10-24-25-19(26)11-23-17-9-14(17)12-6-7-15(21)16(22)8-12/h3-8,10,14,17,23,27H,2,9,11H2,1H3,(H,25,26)/b24-10+/t14-,17+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451583
(CHEMBL4216474)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1cc(O)ccc1O |r| Show InChI InChI=1S/C19H19F2N3O3/c1-10(13-7-12(25)3-5-18(13)26)23-24-19(27)9-22-17-8-14(17)11-2-4-15(20)16(21)6-11/h2-7,14,17,22,25-26H,8-9H2,1H3,(H,24,27)/b23-10+/t14-,17+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 148 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451590
(CHEMBL4215722)Show SMILES COc1ccc(\C=N\NC(=O)CN[C@@H]2C[C@H]2c2ccc(F)c(F)c2)c(O)c1 |r| Show InChI InChI=1S/C19H19F2N3O3/c1-27-13-4-2-12(18(25)7-13)9-23-24-19(26)10-22-17-8-14(17)11-3-5-15(20)16(21)6-11/h2-7,9,14,17,22,25H,8,10H2,1H3,(H,24,26)/b23-9+/t14-,17+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451576
(CHEMBL4205178)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1ccccc1 |r| Show InChI InChI=1S/C19H19F2N3O/c1-12(13-5-3-2-4-6-13)23-24-19(25)11-22-18-10-15(18)14-7-8-16(20)17(21)9-14/h2-9,15,18,22H,10-11H2,1H3,(H,24,25)/b23-12+/t15-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 201 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451582
(CHEMBL4214175)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1ccccc1O |r| Show InChI InChI=1S/C19H19F2N3O2/c1-11(13-4-2-3-5-18(13)25)23-24-19(26)10-22-17-9-14(17)12-6-7-15(20)16(21)8-12/h2-8,14,17,22,25H,9-10H2,1H3,(H,24,26)/b23-11+/t14-,17+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 222 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451578
(CHEMBL4209901)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1ccc(Br)cc1 |r| Show InChI InChI=1S/C19H18BrF2N3O/c1-11(12-2-5-14(20)6-3-12)24-25-19(26)10-23-18-9-15(18)13-4-7-16(21)17(22)8-13/h2-8,15,18,23H,9-10H2,1H3,(H,25,26)/b24-11+/t15-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 223 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451577
(CHEMBL4203790)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C19H18ClF2N3O/c1-11(12-2-5-14(20)6-3-12)24-25-19(26)10-23-18-9-15(18)13-4-7-16(21)17(22)8-13/h2-8,15,18,23H,9-10H2,1H3,(H,25,26)/b24-11+/t15-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 224 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451596
(CHEMBL4203515)Show SMILES CCN(CC)c1ccc(\C=N\NC(=O)CN[C@@H]2C[C@H]2c2ccc(F)c(F)c2)cc1 |r| Show InChI InChI=1S/C22H26F2N4O/c1-3-28(4-2)17-8-5-15(6-9-17)13-26-27-22(29)14-25-21-12-18(21)16-7-10-19(23)20(24)11-16/h5-11,13,18,21,25H,3-4,12,14H2,1-2H3,(H,27,29)/b26-13+/t18-,21+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 254 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451587
(CHEMBL4214864)Show SMILES Fc1ccc(cc1F)[C@@H]1C[C@H]1NCC(=O)N\N=C\c1cccs1 |r| Show InChI InChI=1S/C16H15F2N3OS/c17-13-4-3-10(6-14(13)18)12-7-15(12)19-9-16(22)21-20-8-11-2-1-5-23-11/h1-6,8,12,15,19H,7,9H2,(H,21,22)/b20-8+/t12-,15+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 274 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451585
(CHEMBL4217387)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1cc(F)ccc1O |r| Show InChI InChI=1S/C19H18F3N3O2/c1-10(13-7-12(20)3-5-18(13)26)24-25-19(27)9-23-17-8-14(17)11-2-4-15(21)16(22)6-11/h2-7,14,17,23,26H,8-9H2,1H3,(H,25,27)/b24-10+/t14-,17+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 274 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451594
(CHEMBL4212293)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1cccc(N)c1O |r| Show InChI InChI=1S/C19H20F2N4O2/c1-10(12-3-2-4-16(22)19(12)27)24-25-18(26)9-23-17-8-13(17)11-5-6-14(20)15(21)7-11/h2-7,13,17,23,27H,8-9,22H2,1H3,(H,25,26)/b24-10+/t13-,17+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 349 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451580
(CHEMBL4202897)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1ccc(cc1)[N+]([O-])=O |r| Show InChI InChI=1S/C19H18F2N4O3/c1-11(12-2-5-14(6-3-12)25(27)28)23-24-19(26)10-22-18-9-15(18)13-4-7-16(20)17(21)8-13/h2-8,15,18,22H,9-10H2,1H3,(H,24,26)/b23-11+/t15-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451586
(CHEMBL4209645)Show SMILES Fc1ccc(cc1F)[C@@H]1C[C@H]1NCC(=O)N\N=C\c1ccco1 |r| Show InChI InChI=1S/C16H15F2N3O2/c17-13-4-3-10(6-14(13)18)12-7-15(12)19-9-16(22)21-20-8-11-2-1-5-23-11/h1-6,8,12,15,19H,7,9H2,(H,21,22)/b20-8+/t12-,15+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 367 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451595
(CHEMBL4211184)Show SMILES Oc1ccc(Br)cc1\C=N\NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C18H16BrF2N3O2/c19-12-2-4-17(25)11(5-12)8-23-24-18(26)9-22-16-7-13(16)10-1-3-14(20)15(21)6-10/h1-6,8,13,16,22,25H,7,9H2,(H,24,26)/b23-8+/t13-,16+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 388 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451581
(CHEMBL4214311)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1cccc(N)c1 |r| Show InChI InChI=1S/C19H20F2N4O/c1-11(12-3-2-4-14(22)7-12)24-25-19(26)10-23-18-9-15(18)13-5-6-16(20)17(21)8-13/h2-8,15,18,23H,9-10,22H2,1H3,(H,25,26)/b24-11+/t15-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 423 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451588
(CHEMBL4206303)Show SMILES Oc1ccc(Cl)cc1\C=N\NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C18H16ClF2N3O2/c19-12-2-4-17(25)11(5-12)8-23-24-18(26)9-22-16-7-13(16)10-1-3-14(20)15(21)6-10/h1-6,8,13,16,22,25H,7,9H2,(H,24,26)/b23-8+/t13-,16+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 456 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50231781
(CHEMBL4090528)Show SMILES C(Sc1nc(Sc2ccccn2)c2nnn(Cc3ccccc3)c2n1)c1ccccc1 Show InChI InChI=1S/C23H18N6S2/c1-3-9-17(10-4-1)15-29-21-20(27-28-29)22(31-19-13-7-8-14-24-19)26-23(25-21)30-16-18-11-5-2-6-12-18/h1-14H,15-16H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 564 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay |
ACS Med Chem Lett 8: 384-389 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00423
BindingDB Entry DOI: 10.7270/Q2FQ9ZV3 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451579
(CHEMBL4210623)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1ccc(F)cc1 |r| Show InChI InChI=1S/C19H18F3N3O/c1-11(12-2-5-14(20)6-3-12)24-25-19(26)10-23-18-9-15(18)13-4-7-16(21)17(22)8-13/h2-8,15,18,23H,9-10H2,1H3,(H,25,26)/b24-11+/t15-,18+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50231773
(CHEMBL4069511)Show InChI InChI=1S/C19H14N6S2/c1-2-12-26-19-21-17-16(18(22-19)27-15-10-6-7-11-20-15)23-24-25(17)13-14-8-4-3-5-9-14/h1,3-11H,12-13H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 678 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay |
ACS Med Chem Lett 8: 384-389 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00423
BindingDB Entry DOI: 10.7270/Q2FQ9ZV3 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50231771
(CHEMBL4087193)Show InChI InChI=1S/C19H18N6S2/c1-2-12-26-19-21-17-16(18(22-19)27-15-10-6-7-11-20-15)23-24-25(17)13-14-8-4-3-5-9-14/h3-11H,2,12-13H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 685 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay |
ACS Med Chem Lett 8: 384-389 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00423
BindingDB Entry DOI: 10.7270/Q2FQ9ZV3 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50231780
(CHEMBL4065771)Show InChI InChI=1S/C18H18N6S3/c1-2-11-26-18-20-16-15(17(21-18)27-14-7-3-4-9-19-14)22-23-24(16)10-8-13-6-5-12-25-13/h3-7,9,12H,2,8,10-11H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 717 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay |
ACS Med Chem Lett 8: 384-389 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00423
BindingDB Entry DOI: 10.7270/Q2FQ9ZV3 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50231778
(CHEMBL4068480)Show InChI InChI=1S/C17H16N6OS2/c1-2-10-25-17-19-15-14(16(20-17)26-13-7-3-4-8-18-13)21-22-23(15)11-12-6-5-9-24-12/h3-9H,2,10-11H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 758 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay |
ACS Med Chem Lett 8: 384-389 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00423
BindingDB Entry DOI: 10.7270/Q2FQ9ZV3 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451584
(CHEMBL4209568)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1cc(Br)ccc1O |r| Show InChI InChI=1S/C19H18BrF2N3O2/c1-10(13-7-12(20)3-5-18(13)26)24-25-19(27)9-23-17-8-14(17)11-2-4-15(21)16(22)6-11/h2-7,14,17,23,26H,8-9H2,1H3,(H,25,27)/b24-10+/t14-,17+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 828 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50451593
(CHEMBL4208534)Show SMILES C\C(=N/NC(=O)CN[C@@H]1C[C@H]1c1ccc(F)c(F)c1)c1cc(Cl)ccc1O |r| Show InChI InChI=1S/C19H18ClF2N3O2/c1-10(13-7-12(20)3-5-18(13)26)24-25-19(27)9-23-17-8-14(17)11-2-4-15(21)16(22)6-11/h2-7,14,17,23,26H,8-9H2,1H3,(H,25,27)/b24-10+/t14-,17+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 882 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of LSD1 (unknown origin) |
Bioorg Med Chem Lett 27: 5036-5039 (2017)
Article DOI: 10.1016/j.bmcl.2017.10.003
BindingDB Entry DOI: 10.7270/Q2J105QD |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50526215
(CHEMBL1192435)Show InChI InChI=1S/C13H14N6S/c1-9-7-11(17-14)19-12(15-9)16-13(18-19)20-8-10-5-3-2-4-6-10/h2-7,17H,8,14H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 882 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay |
Eur J Med Chem 166: 432-444 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.075
BindingDB Entry DOI: 10.7270/Q29S1VGB |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50231754
(CHEMBL4074390)Show InChI InChI=1S/C16H20N6S2/c1-4-9-23-16-18-14-13(20-21-22(14)10-11(2)3)15(19-16)24-12-7-5-6-8-17-12/h5-8,11H,4,9-10H2,1-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 960 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay |
ACS Med Chem Lett 8: 384-389 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00423
BindingDB Entry DOI: 10.7270/Q2FQ9ZV3 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50231769
(CHEMBL4094875)Show InChI InChI=1S/C17H20N6S2/c1-2-11-24-17-19-15-14(21-22-23(15)12-7-3-4-8-12)16(20-17)25-13-9-5-6-10-18-13/h5-6,9-10,12H,2-4,7-8,11H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay |
ACS Med Chem Lett 8: 384-389 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00423
BindingDB Entry DOI: 10.7270/Q2FQ9ZV3 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50524592
(CHEMBL4550944)Show SMILES OC(C1COC(=O)C1=C)c1cn(Cc2ccc(F)cc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C21H17ClFNO3/c1-12-18(11-27-21(12)26)20(25)17-10-24(9-13-2-5-15(23)6-3-13)19-7-4-14(22)8-16(17)19/h2-8,10,18,20,25H,1,9,11H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ... |
Eur J Med Chem 175: 357-372 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.065
BindingDB Entry DOI: 10.7270/Q2X351W0 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50526207
(CHEMBL4529482)Show InChI InChI=1S/C15H13ClN6S2/c1-8-4-13(20-17)22-14(18-8)19-15(21-22)24-7-9-6-23-12-3-2-10(16)5-11(9)12/h2-6,20H,7,17H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay |
Eur J Med Chem 166: 432-444 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.075
BindingDB Entry DOI: 10.7270/Q29S1VGB |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50523251
(CHEMBL4475385)Show SMILES CN1CCN(CC1)c1ccc(Nc2cc(C)nc3nc(SCc4nc5ccccc5[nH]4)nn23)cc1 Show InChI InChI=1S/C25H27N9S/c1-17-15-23(27-18-7-9-19(10-8-18)33-13-11-32(2)12-14-33)34-24(26-17)30-25(31-34)35-16-22-28-20-5-3-4-6-21(20)29-22/h3-10,15,27H,11-14,16H2,1-2H3,(H,28,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 substrate by amplex red and horseradish peroxida... |
Eur J Med Chem 167: 388-401 (2019)
Article DOI: 10.1016/j.ejmech.2019.02.039
BindingDB Entry DOI: 10.7270/Q2ST7T7R |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50524624
(CHEMBL4470161)Show SMILES Cc1ccc(cc1)S(=O)(=O)n1cc(C(O)C2COC(=O)C2=C)c2cc(Cl)ccc12 Show InChI InChI=1S/C21H18ClNO5S/c1-12-3-6-15(7-4-12)29(26,27)23-10-17(16-9-14(22)5-8-19(16)23)20(24)18-11-28-21(25)13(18)2/h3-10,18,20,24H,2,11H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ... |
Eur J Med Chem 175: 357-372 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.065
BindingDB Entry DOI: 10.7270/Q2X351W0 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50526193
(CHEMBL4455265)Show InChI InChI=1S/C14H13F3N6S/c1-8-6-11(21-18)23-12(19-8)20-13(22-23)24-7-9-2-4-10(5-3-9)14(15,16)17/h2-6,21H,7,18H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay |
Eur J Med Chem 166: 432-444 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.075
BindingDB Entry DOI: 10.7270/Q29S1VGB |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50231776
(CHEMBL4095820)Show InChI InChI=1S/C14H16N6OS2/c1-2-9-22-14-16-12-11(18-19-20(12)7-8-21)13(17-14)23-10-5-3-4-6-15-10/h3-6,21H,2,7-9H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Technology of Drug Preparation (Zhengzhou University)
Curated by ChEMBL
| Assay Description
Inhibition of full length recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay |
ACS Med Chem Lett 8: 384-389 (2017)
Article DOI: 10.1021/acsmedchemlett.6b00423
BindingDB Entry DOI: 10.7270/Q2FQ9ZV3 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50524625
(CHEMBL4545973)Show SMILES OC(C1COC(=O)C1=C)c1cn(Cc2ccc(F)cc2)c2ccccc12 Show InChI InChI=1S/C21H18FNO3/c1-13-18(12-26-21(13)25)20(24)17-11-23(19-5-3-2-4-16(17)19)10-14-6-8-15(22)9-7-14/h2-9,11,18,20,24H,1,10,12H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ... |
Eur J Med Chem 175: 357-372 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.065
BindingDB Entry DOI: 10.7270/Q2X351W0 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50526204
(CHEMBL4527031)Show InChI InChI=1S/C9H10N6S/c1-3-4-16-9-12-8-11-6(2)5-7(13-10)15(8)14-9/h1,5,13H,4,10H2,2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay |
Eur J Med Chem 166: 432-444 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.075
BindingDB Entry DOI: 10.7270/Q29S1VGB |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50524596
(CHEMBL4545461)Show InChI InChI=1S/C21H18FNO3/c1-13-17(12-26-21(13)25)20(24)16-11-23(19-9-5-3-7-15(16)19)10-14-6-2-4-8-18(14)22/h2-9,11,17,20,24H,1,10,12H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ... |
Eur J Med Chem 175: 357-372 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.065
BindingDB Entry DOI: 10.7270/Q2X351W0 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50526196
(CHEMBL4572016)Show InChI InChI=1S/C13H13ClN6S/c1-8-6-11(18-15)20-12(16-8)17-13(19-20)21-7-9-2-4-10(14)5-3-9/h2-6,18H,7,15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay |
Eur J Med Chem 166: 432-444 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.075
BindingDB Entry DOI: 10.7270/Q29S1VGB |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50524640
(CHEMBL4456313)Show SMILES OC(C1COC(=O)C1=C)c1cn(Cc2ccc(Cl)nc2)c2ccccc12 Show InChI InChI=1S/C20H17ClN2O3/c1-12-16(11-26-20(12)25)19(24)15-10-23(17-5-3-2-4-14(15)17)9-13-6-7-18(21)22-8-13/h2-8,10,16,19,24H,1,9,11H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ... |
Eur J Med Chem 175: 357-372 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.065
BindingDB Entry DOI: 10.7270/Q2X351W0 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50526210
(CHEMBL4440289)Show InChI InChI=1S/C14H16N6S/c1-9-3-5-11(6-4-9)8-21-14-17-13-16-10(2)7-12(18-15)20(13)19-14/h3-7,18H,8,15H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay |
Eur J Med Chem 166: 432-444 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.075
BindingDB Entry DOI: 10.7270/Q29S1VGB |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50524598
(CHEMBL4591471)Show SMILES OC(C1COC(=O)C1=C)c1cn(Cc2ccc(Cl)c(Cl)c2)c2ccccc12 Show InChI InChI=1S/C21H17Cl2NO3/c1-12-16(11-27-21(12)26)20(25)15-10-24(19-5-3-2-4-14(15)19)9-13-6-7-17(22)18(23)8-13/h2-8,10,16,20,25H,1,9,11H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ... |
Eur J Med Chem 175: 357-372 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.065
BindingDB Entry DOI: 10.7270/Q2X351W0 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50526197
(CHEMBL4443596)Show InChI InChI=1S/C13H13FN6S/c1-8-6-11(18-15)20-12(16-8)17-13(19-20)21-7-9-2-4-10(14)5-3-9/h2-6,18H,7,15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay |
Eur J Med Chem 166: 432-444 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.075
BindingDB Entry DOI: 10.7270/Q29S1VGB |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50526199
(CHEMBL4457116)Show InChI InChI=1S/C9H12N6S/c1-3-4-16-9-12-8-11-6(2)5-7(13-10)15(8)14-9/h3,5,13H,1,4,10H2,2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) using H3K4me2 as substrate by fluorescence assay |
Eur J Med Chem 166: 432-444 (2019)
Article DOI: 10.1016/j.ejmech.2019.01.075
BindingDB Entry DOI: 10.7270/Q29S1VGB |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50524602
(CHEMBL4592421)Show SMILES OC(C1COC(=O)C1=C)c1cn(Cc2ccc(Cl)nc2)c2ccc(Cl)cc12 Show InChI InChI=1S/C20H16Cl2N2O3/c1-11-16(10-27-20(11)26)19(25)15-9-24(8-12-2-5-18(22)23-7-12)17-4-3-13(21)6-14(15)17/h2-7,9,16,19,25H,1,8,10H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ... |
Eur J Med Chem 175: 357-372 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.065
BindingDB Entry DOI: 10.7270/Q2X351W0 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50524603
(CHEMBL4439541)Show SMILES COCCCOc1ccnc(Cn2cc(C(O)C3COC(=O)C3=C)c3cc(Cl)ccc23)c1C Show InChI InChI=1S/C25H27ClN2O5/c1-15-20(14-33-25(15)30)24(29)19-12-28(22-6-5-17(26)11-18(19)22)13-21-16(2)23(7-8-27-21)32-10-4-9-31-3/h5-8,11-12,20,24,29H,1,4,9-10,13-14H2,2-3H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ... |
Eur J Med Chem 175: 357-372 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.065
BindingDB Entry DOI: 10.7270/Q2X351W0 |
More data for this
Ligand-Target Pair | |
Lysine-specific histone demethylase 1A
(Homo sapiens (Human)) | BDBM50524629
(CHEMBL4527359)Show SMILES OC(C1COC(=O)C1=C)c1cn(Cc2ccccc2C(F)(F)F)c2ccccc12 Show InChI InChI=1S/C22H18F3NO3/c1-13-17(12-29-21(13)28)20(27)16-11-26(19-9-5-3-7-15(16)19)10-14-6-2-4-8-18(14)22(23,24)25/h2-9,11,17,20,27H,1,10,12H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Zhengzhou University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant LSD1 (unknown origin) (catalytic domain 157 to 852 residues) expressed in Escherichia coli BL21 using H3K4me1 as substrate ... |
Eur J Med Chem 175: 357-372 (2019)
Article DOI: 10.1016/j.ejmech.2019.04.065
BindingDB Entry DOI: 10.7270/Q2X351W0 |
More data for this
Ligand-Target Pair | |
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