Found 674 hits with Last Name = 'keum' and Initial = 'g' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50098551
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.339 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50098551
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50098551
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50004891
(CHEMBL2164327)Show SMILES CN(C)[C@H]1CCc2c(C1)cccc2-c1c(C)nn(C)c1C |r,wD:3.2,(25.25,-11.88,;25.26,-10.34,;26.59,-9.58,;23.93,-9.57,;23.93,-8.02,;22.58,-7.23,;21.24,-8.01,;21.24,-9.57,;22.58,-10.34,;19.91,-10.33,;18.58,-9.56,;18.58,-8.02,;19.91,-7.25,;19.9,-5.71,;21.14,-4.8,;22.6,-5.28,;20.66,-3.34,;19.12,-3.35,;18.21,-2.1,;18.65,-4.81,;17.18,-5.29,)| Show InChI InChI=1S/C18H25N3/c1-12-18(13(2)21(5)19-12)17-8-6-7-14-11-15(20(3)4)9-10-16(14)17/h6-8,15H,9-11H2,1-5H3/t15-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT7 receptor expressed in HEK-293F cells |
Bioorg Med Chem 21: 2568-76 (2013)
Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human)) | BDBM50098551
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.780 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to 5HT5A receptor (unknown origin) |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50098551
((R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolid...)Show SMILES CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1 |r| Show InChI InChI=1S/C18H28N2O3S/c1-15-7-11-19(12-8-15)13-9-16-4-3-10-20(16)24(22,23)18-6-2-5-17(21)14-18/h2,5-6,14-16,21H,3-4,7-13H2,1H3/t16-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT7 receptor (unknown origin) |
Bioorg Med Chem 21: 2568-76 (2013)
Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573235
(CHEMBL4877603) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 6.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573235
(CHEMBL4877603) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| 6.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50058069
(CHEMBL3326993)Show SMILES COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccccc2-c2ccccc2Cl)CC1 Show InChI InChI=1S/C30H36ClN3O2/c1-36-29-16-9-8-15-28(29)34-21-19-33(20-22-34)18-10-2-3-17-30(35)32-23-24-11-4-5-12-25(24)26-13-6-7-14-27(26)31/h4-9,11-16H,2-3,10,17-23H2,1H3,(H,32,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Binding affinity to 5-HT1B (unknown origin) |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058214
(CHEMBL3326982)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccccc2Cl)CC1 Show InChI InChI=1S/C29H34ClN3O2/c1-35-28-15-7-6-14-27(28)33-20-18-32(19-21-33)17-9-8-16-29(34)31-22-23-10-2-3-11-24(23)25-12-4-5-13-26(25)30/h2-7,10-15H,8-9,16-22H2,1H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHOK1 cells |
Bioorg Med Chem 21: 2568-76 (2013)
Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| DrugBank
Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHOK1 cells |
Bioorg Med Chem 21: 2568-76 (2013)
Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50058069
(CHEMBL3326993)Show SMILES COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccccc2-c2ccccc2Cl)CC1 Show InChI InChI=1S/C30H36ClN3O2/c1-36-29-16-9-8-15-28(29)34-21-19-33(20-22-34)18-10-2-3-17-30(35)32-23-24-11-4-5-12-25(24)26-13-6-7-14-27(26)31/h4-9,11-16H,2-3,10,17-23H2,1H3,(H,32,35) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Binding affinity to 5-HT1A (unknown origin) |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573233
(CHEMBL4876193) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573233
(CHEMBL4876193) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573236
(CHEMBL4854605) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573236
(CHEMBL4854605) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058069
(CHEMBL3326993)Show SMILES COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccccc2-c2ccccc2Cl)CC1 Show InChI InChI=1S/C30H36ClN3O2/c1-36-29-16-9-8-15-28(29)34-21-19-33(20-22-34)18-10-2-3-17-30(35)32-23-24-11-4-5-12-25(24)26-13-6-7-14-27(26)31/h4-9,11-16H,2-3,10,17-23H2,1H3,(H,32,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50573248
(CHEMBL4848305) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to 5HT2C receptor (unknown origin) |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573248
(CHEMBL4848305) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573248
(CHEMBL4848305) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50058214
(CHEMBL3326982)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccccc2Cl)CC1 Show InChI InChI=1S/C29H34ClN3O2/c1-35-28-15-7-6-14-27(28)33-20-18-32(19-21-33)17-9-8-16-29(34)31-22-23-10-2-3-11-24(23)25-12-4-5-13-26(25)30/h2-7,10-15H,8-9,16-22H2,1H3,(H,31,34) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Binding affinity to 5-HT1A (unknown origin) |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573237
(CHEMBL4866412) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058162
(CHEMBL3326986)Show SMILES COc1cccc(c1)-c1ccccc1CNC(=O)CCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C30H37N3O3/c1-35-26-12-9-11-24(22-26)27-13-4-3-10-25(27)23-31-30(34)16-7-8-17-32-18-20-33(21-19-32)28-14-5-6-15-29(28)36-2/h3-6,9-15,22H,7-8,16-21,23H2,1-2H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573237
(CHEMBL4866412) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573249
(CHEMBL4858338) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573249
(CHEMBL4858338) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573253
(CHEMBL4852622) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058156
(CHEMBL3326989)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccccc2C)CC1 Show InChI InChI=1S/C30H37N3O2/c1-24-11-3-5-13-26(24)27-14-6-4-12-25(27)23-31-30(34)17-9-10-18-32-19-21-33(22-20-32)28-15-7-8-16-29(28)35-2/h3-8,11-16H,9-10,17-23H2,1-2H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50058214
(CHEMBL3326982)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccccc2Cl)CC1 Show InChI InChI=1S/C29H34ClN3O2/c1-35-28-15-7-6-14-27(28)33-20-18-32(19-21-33)17-9-8-16-29(34)31-22-23-10-2-3-11-24(23)25-12-4-5-13-26(25)30/h2-7,10-15H,8-9,16-22H2,1H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Binding affinity to 5-HT2C (unknown origin) |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058211
(CHEMBL3326984)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C29H34ClN3O2/c1-35-28-11-5-4-10-27(28)33-20-18-32(19-21-33)17-7-6-12-29(34)31-22-24-8-2-3-9-26(24)23-13-15-25(30)16-14-23/h2-5,8-11,13-16H,6-7,12,17-22H2,1H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573253
(CHEMBL4852622) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573234
(CHEMBL4863868) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573234
(CHEMBL4863868) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058209
(CHEMBL3326985)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccccc2OC)CC1 Show InChI InChI=1S/C30H37N3O3/c1-35-28-15-7-5-13-26(28)25-12-4-3-11-24(25)23-31-30(34)17-9-10-18-32-19-21-33(22-20-32)27-14-6-8-16-29(27)36-2/h3-8,11-16H,9-10,17-23H2,1-2H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573238
(CHEMBL4869695) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50573238
(CHEMBL4869695) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) transfected in HEK293 cells incubated for 1.5 hrs by liquid scintillation counting |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058157
(CHEMBL3326988)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2c(OC)cccc2OC)CC1 |(26.8,-10.21,;25.47,-10.98,;25.48,-12.52,;26.82,-13.29,;26.82,-14.83,;25.49,-15.6,;24.15,-14.83,;24.16,-13.3,;22.83,-12.53,;21.49,-13.3,;20.16,-12.53,;20.16,-10.98,;18.82,-10.22,;17.49,-11,;16.16,-10.23,;14.83,-11.01,;13.49,-10.25,;13.48,-8.71,;12.16,-11.02,;10.82,-10.25,;9.49,-11.03,;9.5,-12.58,;8.16,-13.35,;6.82,-12.58,;6.83,-11.04,;8.16,-10.27,;8.15,-8.73,;6.81,-7.97,;5.47,-8.76,;5.49,-10.31,;6.8,-6.43,;8.14,-5.65,;9.48,-6.42,;9.48,-7.96,;10.81,-8.73,;12.16,-7.95,;21.49,-10.21,;22.82,-10.99,)| Show InChI InChI=1S/C31H39N3O4/c1-36-27-14-7-6-13-26(27)34-21-19-33(20-22-34)18-9-8-17-30(35)32-23-24-11-4-5-12-25(24)31-28(37-2)15-10-16-29(31)38-3/h4-7,10-16H,8-9,17-23H2,1-3H3,(H,32,35) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50098550
(3,N-Dimethyl-N-[(R)-1-methyl-3-(4-methyl-piperidin...)Show SMILES C[C@H](CCN1CCC(C)CC1)N(C)S(=O)(=O)c1cccc(C)c1 Show InChI InChI=1S/C18H30N2O2S/c1-15-8-11-20(12-9-15)13-10-17(3)19(4)23(21,22)18-7-5-6-16(2)14-18/h5-7,14-15,17H,8-13H2,1-4H3/t17-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT7 receptor (unknown origin) |
Bioorg Med Chem 21: 2568-76 (2013)
Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058216
(CHEMBL3326980)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2cccc(F)c2)CC1 Show InChI InChI=1S/C29H34FN3O2/c1-35-28-14-5-4-13-27(28)33-19-17-32(18-20-33)16-7-6-15-29(34)31-22-24-9-2-3-12-26(24)23-10-8-11-25(30)21-23/h2-5,8-14,21H,6-7,15-20,22H2,1H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058215
(CHEMBL3326981)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccc(F)cc2)CC1 Show InChI InChI=1S/C29H34FN3O2/c1-35-28-11-5-4-10-27(28)33-20-18-32(19-21-33)17-7-6-12-29(34)31-22-24-8-2-3-9-26(24)23-13-15-25(30)16-14-23/h2-5,8-11,13-16H,6-7,12,17-22H2,1H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058217
(CHEMBL3326979)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccccc2F)CC1 Show InChI InChI=1S/C29H34FN3O2/c1-35-28-15-7-6-14-27(28)33-20-18-32(19-21-33)17-9-8-16-29(34)31-22-23-10-2-3-11-24(23)25-12-4-5-13-26(25)30/h2-7,10-15H,8-9,16-22H2,1H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058219
(CHEMBL3325464)Show SMILES COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2ccccc2)CC1 Show InChI InChI=1S/C29H35N3O2/c1-34-28-16-8-7-15-27(28)32-21-19-31(20-22-32)18-10-9-17-29(33)30-23-25-13-5-6-14-26(25)24-11-3-2-4-12-24/h2-8,11-16H,9-10,17-23H2,1H3,(H,30,33) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50573251
(CHEMBL4856702) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Binding affinity to 5HT2C receptor (unknown origin) |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01093
BindingDB Entry DOI: 10.7270/Q2833WTS |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50004894
(CHEMBL2376461)Show InChI InChI=1S/C25H28N2O2/c1-28-24-13-7-5-11-22(24)21-10-4-3-9-20(21)19-26-15-17-27(18-16-26)23-12-6-8-14-25(23)29-2/h3-14H,15-19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHOK1 cells |
Bioorg Med Chem 21: 2568-76 (2013)
Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50004894
(CHEMBL2376461)Show InChI InChI=1S/C25H28N2O2/c1-28-24-13-7-5-11-22(24)21-10-4-3-9-20(21)19-26-15-17-27(18-16-26)23-12-6-8-14-25(23)29-2/h3-14H,15-19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHOK1 cells |
Bioorg Med Chem 21: 2568-76 (2013)
Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058218
(CHEMBL3326978)Show SMILES COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccccc2-c2ccccc2)CC1 Show InChI InChI=1S/C30H37N3O2/c1-35-29-17-10-9-16-28(29)33-22-20-32(21-23-33)19-11-3-6-18-30(34)31-24-26-14-7-8-15-27(26)25-12-4-2-5-13-25/h2,4-5,7-10,12-17H,3,6,11,18-24H2,1H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50058159
(CHEMBL3326987)Show SMILES COc1ccc(cc1)-c1ccccc1CNC(=O)CCCCN1CCN(CC1)c1ccccc1OC Show InChI InChI=1S/C30H37N3O3/c1-35-26-16-14-24(15-17-26)27-10-4-3-9-25(27)23-31-30(34)13-7-8-18-32-19-21-33(22-20-32)28-11-5-6-12-29(28)36-2/h3-6,9-12,14-17H,7-8,13,18-23H2,1-2H3,(H,31,34) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yonsei University
Curated by ChEMBL
| Assay Description
Displacement of [3H]LSD from 5-HT7R (unknown origin) expressed in CHO-K1 cells by liquid scintillation counting method |
Bioorg Med Chem 22: 4587-96 (2014)
Article DOI: 10.1016/j.bmc.2014.07.026
BindingDB Entry DOI: 10.7270/Q22N53ZG |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50004892
(CHEMBL2375370)Show InChI InChI=1S/C25H28N2O2/c1-28-22-13-11-20(12-14-22)23-8-4-3-7-21(23)19-26-15-17-27(18-16-26)24-9-5-6-10-25(24)29-2/h3-14H,15-19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHOK1 cells |
Bioorg Med Chem 21: 2568-76 (2013)
Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50004892
(CHEMBL2375370)Show InChI InChI=1S/C25H28N2O2/c1-28-22-13-11-20(12-14-22)23-8-4-3-7-21(23)19-26-15-17-27(18-16-26)24-9-5-6-10-25(24)29-2/h3-14H,15-19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Science and Technology
Curated by ChEMBL
| Assay Description
Displacement of [3H]-LSD from 5HT7 receptor (unknown origin) expressed in CHOK1 cells |
Bioorg Med Chem 21: 2568-76 (2013)
Article DOI: 10.1016/j.bmc.2013.02.038
BindingDB Entry DOI: 10.7270/Q2QZ2CGC |
More data for this
Ligand-Target Pair | |
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