Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human)) | BDBM194644 (US9206139, 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant ADAMTS5 using synthetic peptide as substrate by FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02008 BindingDB Entry DOI: 10.7270/Q21R6VBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM379774 (US9926281, Compound 279 | US9926281, Compound 448) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description MMP2: Protocol 2: The basis for the assay is the cleavage of the substrate 390 MMP FRET substrate I (Anaspec, Catalog n#: AS-27076) by human MMP2 (R&... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 4 (Homo sapiens (Human)) | BDBM194644 (US9206139, 3) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant ADAMTS4 using synthetic peptide as substrate by FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02008 BindingDB Entry DOI: 10.7270/Q21R6VBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM379670 (US9926281, Compound 194 | US9926281, Compound 413) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM379686 (US9926281, Compound 212) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Collagenase 3 (Homo sapiens (Human)) | BDBM379776 (US9926281, Compound 234) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description MMP-13:The basis for the assay is the cleavage of the substrate 390 MMP FRET Substrate I (Anaspec Cat # AS-27076) by human MMP13 (Chemicon, Cat #CC06... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM379681 (US9926281, Compound 207 | US9926281, Compound 416) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM379668 (US9926281, Compound 192 | US9926281, Compound 411) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM379669 (US9926281, Compound 193 | US9926281, Compound 412) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM379653 (US9926281, Compound 176) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-14 (Homo sapiens (Human)) | BDBM379901 (US9926281, Compound 396) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description MMP-14:The basis for the assay is the cleavage of the substrate 390 MMP FRET Substrate I (Anaspec Cat # AS-27076) by human MMP14 (Biomol, Cat #SE-259... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-14 (Homo sapiens (Human)) | BDBM379776 (US9926281, Compound 234) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description MMP-14:The basis for the assay is the cleavage of the substrate 390 MMP FRET Substrate I (Anaspec Cat # AS-27076) by human MMP14 (Biomol, Cat #SE-259... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human)) | BDBM50575720 (CHEMBL4864283) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant ADAMTS5 using synthetic peptide as substrate by FRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02008 BindingDB Entry DOI: 10.7270/Q21R6VBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM379645 (US9926281, Compound 167 | US9926281, Compound 408) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human)) | BDBM379668 (US9926281, Compound 192 | US9926281, Compound 411) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human)) | BDBM379670 (US9926281, Compound 194 | US9926281, Compound 413) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM379667 (US9926281, Compound 191) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human)) | BDBM379670 (US9926281, Compound 194 | US9926281, Compound 413) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM379649 (US9926281, Compound 172 | US9926281, Compound 409) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human)) | BDBM379668 (US9926281, Compound 192 | US9926281, Compound 411) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM379678 (US9926281, Compound 204) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-4:The basis for the assay is the cleavage of the substrate TBIS-1 (5-FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMTS4For the do... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human)) | BDBM379681 (US9926281, Compound 207 | US9926281, Compound 416) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human)) | BDBM379686 (US9926281, Compound 212) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human)) | BDBM379686 (US9926281, Compound 212) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant ADAMTS-5 assessed as cleavage of fluorescent substrate using FAM-TBIS-1 by biochemical assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02008 BindingDB Entry DOI: 10.7270/Q21R6VBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 4 (Homo sapiens (Human)) | BDBM379975 (US9926281, Compound 436) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant ADAMTS-4 (AA1 to 520) assessed as cleavage of fluorescent substrate using as TBIS-1 substrate incubated for 180 mins ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02008 BindingDB Entry DOI: 10.7270/Q21R6VBM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 5 (Homo sapiens (Human)) | BDBM379681 (US9926281, Compound 207 | US9926281, Compound 416) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois at Chicago | Assay Description ADAMTS-5:Protocol 2: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID No 2) by human ADAMT... | J Med Chem 51: 3437-48 (2008) BindingDB Entry DOI: 10.7270/Q27S7R3T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429689 (5-(3-(4-(4- chloro-3,5- dimethoxy- phenyl)piperidi...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429691 (5-(3-(4-(4- chlorophenyl) piperidin-1- yl)-2-methy...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429692 (5-(3-(4-(3,5- dichlorophenyl) piperidin-1- yl)-2-m...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429715 (5-(3-(4-(4- chloro-3- methoxyl- phenyl)piperidin-1...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429716 (5-(3-(4-(4- chloro-5- methoxy-2- methylphenyl) pip...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429723 (5-(3-(4-(4- chloro-2- methoxyphenyl) piperidin-1- ...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429724 (5-(3-(4-(3,4- difluoro-5- methoxyphenyl) piperidin...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429725 ((R)-5-(3-(4-(4- chloro-3- fluoro-5- methoxyphenyl)...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429726 (5-(3-(4-(4- chloro-3- fluoro-5- methoxyphenyl) pip...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429740 ((R)-5-(3-(4- (4,5-dichloro- 2- methoxyphenyl) pipe...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429741 (5-(3-(4-(4,5- dichloro-2- methoxyphenyl) piperidin...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429745 ((R)-5-(3-(4-(3- chloro-5- methoxyphenyl) piperidin...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429747 ((R)-5-(3-(4- (3,4-dichloro-5- methoxyphenyl) piper...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429748 ((R)-5-(3-(4- (3,4-dichloro-5- methoxyphenyl) piper...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429750 (5-(3-(4-(4,5- dichloro-2- methylphenyl) piperidin-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429751 (5-(3-(4-(4- fluoro-3,5- dimethoxyphenyl) piperidin...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429752 (5-(3-(4-(3- chloro-4- fluoro-5- methoxyphenyl) pip...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429758 ((5R)-5-[3-[4- (4-chloro-2- methoxy- phenyl)-1- pip...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429759 ((5R)-5-[3-[4- (3-chloro-4- fluoro-5- methoxy- phen...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429760 ((5R)-5-[3-[4- (4-fluoro-3,5- dimethoxy- phenyl)-1-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429761 ((5R)-5-[3-[4- (4-fluoro-3,5- dimethoxy- phenyl)-1-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429763 ((5R)-5-[3-[4- (4-chloro-3- fluoro-5- methoxy- phen...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429765 ((5R)-5-[3-[4- (4-chloro-3- methoxy- phenyl)-1- pip...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human) | BDBM429767 ((5R)-5-[3-[4- (4-chloro-3- ethoxy-5- methoxy- phen...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 12.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair |
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