Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-galactosidase (Coffea arabica (Coffee beans)) | BDBM50520994 (CHEMBL4529797) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
wuhan Institute of Technology Curated by ChEMBL | Assay Description Inhibition of green coffee bean alpha-galactosidase | Eur J Med Chem 162: 465-494 (2019) Article DOI: 10.1016/j.ejmech.2018.11.031 BindingDB Entry DOI: 10.7270/Q2154MGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human)) | BDBM50520989 (CHEMBL4565280) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.0600 | n/a | n/a | n/a | n/a | n/a | n/a |
wuhan Institute of Technology Curated by ChEMBL | Assay Description Inhibition of human recombinant FTase using [3H]FPP as substrate after 15 mins by scintillation counting analysis | Eur J Med Chem 162: 465-494 (2019) Article DOI: 10.1016/j.ejmech.2018.11.031 BindingDB Entry DOI: 10.7270/Q2154MGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human)) | BDBM11823 (Azepane Derivative 4 | N-((3R,4R)-4-{[4-(2-fluoro-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
wuhan Institute of Technology Curated by ChEMBL | Assay Description Inhibition of PKBalpha (unknown origin) expressed in Sf9 insect cells using Biotin-SGRARTSSFAEPG as substrate after 30 mins by ELISA | Eur J Med Chem 162: 465-494 (2019) Article DOI: 10.1016/j.ejmech.2018.11.031 BindingDB Entry DOI: 10.7270/Q2154MGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 2 (Homo sapiens (Human)) | BDBM222462 ((E)-4-[4-(2-Chlorobenzylidene)-2-(4-chlorophenyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Wuhan University of Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human COX2 by EIA | Eur J Med Chem 173: 117-153 (2019) Article DOI: 10.1016/j.ejmech.2019.03.063 BindingDB Entry DOI: 10.7270/Q2QJ7MMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Homo sapiens (Human)) | BDBM50520992 (CHEMBL4438366) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
wuhan Institute of Technology Curated by ChEMBL | Assay Description Inhibition of beta-galactosidase (unknown origin) | Eur J Med Chem 162: 465-494 (2019) Article DOI: 10.1016/j.ejmech.2018.11.031 BindingDB Entry DOI: 10.7270/Q2154MGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable maltase-glucoamylase 2 (Homo sapiens) | BDBM50502118 (CHEMBL4476702) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wuhan University of Technology Curated by ChEMBL | Assay Description Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-a-d-glucopyranoside as substrate preincubated for 5 mins followed by substrate a... | Eur J Med Chem 173: 117-153 (2019) Article DOI: 10.1016/j.ejmech.2019.03.063 BindingDB Entry DOI: 10.7270/Q2QJ7MMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175278 ((E)-2,3-bis(4-Hydroxyphenyl)acrylonitrile (21)) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.06E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin G/H synthase 1 (Ovis aries (Sheep)) | BDBM222462 ((E)-4-[4-(2-Chlorobenzylidene)-2-(4-chlorophenyl)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wuhan University of Technology Curated by ChEMBL | Assay Description Inhibition of ovine COX1 by EIA | Eur J Med Chem 173: 117-153 (2019) Article DOI: 10.1016/j.ejmech.2019.03.063 BindingDB Entry DOI: 10.7270/Q2QJ7MMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Amyloid-beta precursor protein (Homo sapiens (Human)) | BDBM50512315 (CHEMBL4438040) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Wuhan University of Technology Curated by ChEMBL | Assay Description Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation | Eur J Med Chem 173: 117-153 (2019) Article DOI: 10.1016/j.ejmech.2019.03.063 BindingDB Entry DOI: 10.7270/Q2QJ7MMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM23926 ((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.08E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175269 (Trans-4-Styryl-phenol (8)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.74E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Aspergillus oryzae) | BDBM50520993 (CHEMBL4472415) | PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
wuhan Institute of Technology Curated by ChEMBL | Assay Description Inhibition of Aspergillus oryzae beta-galactosidase | Eur J Med Chem 162: 465-494 (2019) Article DOI: 10.1016/j.ejmech.2018.11.031 BindingDB Entry DOI: 10.7270/Q2154MGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-glucuronidase (Homo sapiens (Human)) | BDBM178133 (3-(6-Chloro-1H-imidazo[4,5-b]pyridin-2-yl)benzene-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Wuhan University of Technology Curated by ChEMBL | Assay Description Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-D-glucuronide as substrate pre-incubated for 30 mins followed by substrate... | Eur J Med Chem 173: 117-153 (2019) Article DOI: 10.1016/j.ejmech.2019.03.063 BindingDB Entry DOI: 10.7270/Q2QJ7MMT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175267 (Trans-4-Styrylbenzonitrile (6)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175271 (Trans-1-fluoro-4-(4-methoxystyryl)benzene (10)) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175272 (Trans-2-Bromo-1-methoxy-4-styryl-benzene (11)) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.62E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175263 (Trans-1-Fluoro-4-styryl-benzene (2)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.94E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175275 (Trans-9-Styryl-anthracene (15)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.66E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Aspergillus oryzae) | BDBM50520991 (CHEMBL4581374) | PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
wuhan Institute of Technology Curated by ChEMBL | Assay Description Inhibition of Aspergillus oryzae beta-galactosidase | Eur J Med Chem 162: 465-494 (2019) Article DOI: 10.1016/j.ejmech.2018.11.031 BindingDB Entry DOI: 10.7270/Q2154MGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175279 ((E)-2-(4-Hydroxyphenyl)-3-(pyridin-3-yl)acrylonitr...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.70E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175277 ((E)-3-(4-Methoxyphenyl)-2-phenylpropenal (20)) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.76E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175265 (Trans-1-Bromo-4-styrylbenzene (4)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.77E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Aspergillus oryzae) | BDBM50520990 (CHEMBL4522734) | PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.79E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
wuhan Institute of Technology Curated by ChEMBL | Assay Description Inhibition of Aspergillus oryzae beta-galactosidase | Eur J Med Chem 162: 465-494 (2019) Article DOI: 10.1016/j.ejmech.2018.11.031 BindingDB Entry DOI: 10.7270/Q2154MGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175264 (Trans-1-Chloro-4-styrylbenzene (3)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175266 (Trans-1-Nitro-4-styrylbenzene (5)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.61E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175273 (Trans-1,3-Difluoro-5-styrylbenzene (12)) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.94E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175270 (Trans-1-Methoxy-4-styryl-benzene (9)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.33E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM50006677 (1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175274 (Trans-1,2,3,4,5-Pentafluoro-6-styryl-benzene (14)) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175262 (Trans-1,2-Diphenylethene (1)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175276 ((E)-Methyl-3-(4-hydroxy-3-methoxyphenyl)-2-(4-meth...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Mus musculus (Mouse)) | BDBM175268 (Trans-Acetic acid 4-styryl-phenyl ester (7)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >5.00E+5 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Indian Institute of Integrative Medicine | Assay Description The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres... | Bioorg Chem 64: 97-102 (2016) Article DOI: 10.1016/j.bioorg.2016.01.001 BindingDB Entry DOI: 10.7270/Q28C9V13 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50346541 (CHEMBL1797749) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
wuhan Institute of Technology Curated by ChEMBL | Assay Description Inhibition of SIRT2 (unknown origin) using fluorogenic deacetylase substrate by fluorescence assay | Eur J Med Chem 162: 465-494 (2019) Article DOI: 10.1016/j.ejmech.2018.11.031 BindingDB Entry DOI: 10.7270/Q2154MGW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50008859 (CHEMBL3222141) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.55E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
wuhan Institute of Technology Curated by ChEMBL | Assay Description Inhibition of SIRT2 (unknown origin) using fluorogenic deacetylase substrate by fluorescence assay | Eur J Med Chem 162: 465-494 (2019) Article DOI: 10.1016/j.ejmech.2018.11.031 BindingDB Entry DOI: 10.7270/Q2154MGW | |||||||||||
More data for this Ligand-Target Pair |