Compile Data Set for Download or QSAR

Found 94 hits with Last Name = 'kuriwaki' and Initial = 'i'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50593531 (ASP-5878 | ASP5878 | Asp 5878 | Asp-5878 | Asp5878) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3cnn(CCO)c3)nc2)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50593531 (ASP-5878 | ASP5878 | Asp 5878 | Asp-5878 | Asp5878) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3cnn(CCO)c3)nc2)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593524 (CHEMBL5206147) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(F)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593522 (CHEMBL5170802) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593521 (CHEMBL5182779) Show SMILES Cl.Cl.Cl.Cl.COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCC(CC4)N(C)C4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593525 (CHEMBL5182060) Show SMILES CCOc1cc(Nc2ncc(OCc3c(F)c(OC)cc(OC)c3F)cn2)ccc1N1CCC(CC1)N1CCN(C)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50559408 (CHEMBL4763773) Show SMILES COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50559408 (CHEMBL4763773) Show SMILES COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR2 (399 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593530 (CHEMBL5201061) Show SMILES Cl.Cl.Cl.COc1cc(OC)c(F)c(COc2cnc(Nc3cnn(CCN4CCNCC4)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593526 (CHEMBL5197399) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3cnc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593520 (CHEMBL5194555) Show SMILES COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCN(CC4)C4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593532 (CHEMBL5193271) Show SMILES COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593523 (CHEMBL5171147) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3ccc(N4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50559406 (CHEMBL4746045) Show SMILES COc1cc(OC)c(Cl)c(CCc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593533 (CHEMBL5207973) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(C)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50559408 (CHEMBL4763773) Show SMILES COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR1 (398 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545477 (CHEMBL4635544) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1NC(=O)c1nc(OC)cc(OC)n1 Show InChI InChI=1S/C36H47N11O6S/c1-6-38-54(49,50)30-10-8-7-9-26(30)40-33-27(41-35(48)34-42-31(52-4)22-32(43-34)53-5)23-37-36(44-33)39-24-11-12-28(29(21-24)51-3)47-15-13-25(14-16-47)46-19-17-45(2)18-20-46/h7-12,21-23,25,38H,6,13-20H2,1-5H3,(H,41,48)(H2,37,39,40,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593527 (CHEMBL5191170) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3ccc(nc3)N3CCC(CC3)N3CCN(C)CC3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593531 (ASP-5878 | ASP5878 | Asp 5878 | Asp-5878 | Asp5878) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3cnn(CCO)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50545472 (CHEMBL4642080) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1NC(=O)c1cc(OC)cc(OC)c1 Show InChI InChI=1S/C38H49N9O6S/c1-6-40-54(49,50)35-10-8-7-9-31(35)42-36-32(43-37(48)26-21-29(51-3)24-30(22-26)52-4)25-39-38(44-36)41-27-11-12-33(34(23-27)53-5)47-15-13-28(14-16-47)46-19-17-45(2)18-20-46/h7-12,21-25,28,40H,6,13-20H2,1-5H3,(H,43,48)(H2,39,41,42,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR1 cytoplasmic domain (398-822 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593529 (CHEMBL5197909) Show SMILES Cl.Cl.Cl.COc1cc(OC)c(F)c(COc2cnc(Nc3cnn(CCNC4CCN(C)CC4)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545471 (CHEMBL4634918) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1CCc1cc(OC)cc(OC)c1 Show InChI InChI=1S/C39H52N8O5S/c1-6-41-53(48,49)37-10-8-7-9-34(37)43-38-29(12-11-28-23-32(50-3)26-33(24-28)51-4)27-40-39(44-38)42-30-13-14-35(36(25-30)52-5)47-17-15-31(16-18-47)46-21-19-45(2)20-22-46/h7-10,13-14,23-27,31,41H,6,11-12,15-22H2,1-5H3,(H2,40,42,43,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50525939 (Balversa | Erdafitinib | Jnj-42756493) Show SMILES COc1cc(OC)cc(c1)N(CCNC(C)C)c1ccc2ncc(nc2c1)-c1cnn(C)c1 Show InChI InChI=1S/C25H30N6O2/c1-17(2)26-8-9-31(20-10-21(32-4)13-22(11-20)33-5)19-6-7-23-24(12-19)29-25(15-27-23)18-14-28-30(3)16-18/h6-7,10-17,26H,8-9H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal His6 tagged FGFR3 (447 to 761 residues) expressed in Sf21 cells using FLT3 peptide as substrate preincubat...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50545472 (CHEMBL4642080) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1NC(=O)c1cc(OC)cc(OC)c1 Show InChI InChI=1S/C38H49N9O6S/c1-6-40-54(49,50)35-10-8-7-9-31(35)42-36-32(43-37(48)26-21-29(51-3)24-30(22-26)52-4)25-39-38(44-36)41-27-11-12-33(34(23-27)53-5)47-15-13-28(14-16-47)46-19-17-45(2)18-20-46/h7-12,21-25,28,40H,6,13-20H2,1-5H3,(H,43,48)(H2,39,41,42,44)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR2 cytoplasmic domain (399-821 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593531 (ASP-5878 | ASP5878 | Asp 5878 | Asp-5878 | Asp5878) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3cnn(CCO)c3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545466 (CHEMBL4645817) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1ncnc(Nc2ccc(N3CCN(C)CC3)c(OCCN3CCOCC3)c2)n1 Show InChI InChI=1S/C28H39N9O4S/c1-3-31-42(38,39)26-7-5-4-6-23(26)33-28-30-21-29-27(34-28)32-22-8-9-24(37-12-10-35(2)11-13-37)25(20-22)41-19-16-36-14-17-40-18-15-36/h4-9,20-21,31H,3,10-19H2,1-2H3,(H2,29,30,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545469 (CHEMBL4635284) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1-c1cc(OC)cc(OC)c1 Show InChI InChI=1S/C37H48N8O5S/c1-6-39-51(46,47)35-10-8-7-9-32(35)41-36-31(26-21-29(48-3)24-30(22-26)49-4)25-38-37(42-36)40-27-11-12-33(34(23-27)50-5)45-15-13-28(14-16-45)44-19-17-43(2)18-20-44/h7-12,21-25,28,39H,6,13-20H2,1-5H3,(H2,38,40,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM50559408 (CHEMBL4763773) Show SMILES COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR4 (460 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50559409 (CHEMBL4750924) Show SMILES COc1cc(OC)c(Cl)c(CCc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545472 (CHEMBL4642080) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1NC(=O)c1cc(OC)cc(OC)c1 Show InChI InChI=1S/C38H49N9O6S/c1-6-40-54(49,50)35-10-8-7-9-31(35)42-36-32(43-37(48)26-21-29(51-3)24-30(22-26)52-4)25-39-38(44-36)41-27-11-12-33(34(23-27)53-5)47-15-13-28(14-16-47)46-19-17-45(2)18-20-46/h7-12,21-25,28,40H,6,13-20H2,1-5H3,(H,43,48)(H2,39,41,42,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50593528 (CHEMBL5189378) Show SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3cnc(nc3)N3CCC(CC3)N3CCN(C)CC3)nc2)c1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmc.2022.116657 BindingDB Entry DOI: 10.7270/Q2D79GDB
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50545460 (CHEMBL4641667) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1ncnc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)n1 Show InChI InChI=1S/C28H39N9O3S/c1-4-31-41(38,39)26-8-6-5-7-23(26)33-28-30-20-29-27(34-28)32-21-9-10-24(25(19-21)40-3)37-13-11-22(12-14-37)36-17-15-35(2)16-18-36/h5-10,19-20,22,31H,4,11-18H2,1-3H3,(H2,29,30,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR2 cytoplasmic domain (399-821 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50559407 (CHEMBL4791437) Show SMILES COc1cc(CCc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c(F)c(OC)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM25118 ((3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,...) Show SMILES CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O Show InChI InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of FGFR3 (unknown origin) expressed in baculovirus infected insect cells using biotinylated-GGGGQDGKDYIVLPI peptide as substrate incubated...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545460 (CHEMBL4641667) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1ncnc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)n1 Show InChI InChI=1S/C28H39N9O3S/c1-4-31-41(38,39)26-8-6-5-7-23(26)33-28-30-20-29-27(34-28)32-21-9-10-24(25(19-21)40-3)37-13-11-22(12-14-37)36-17-15-35(2)16-18-36/h5-10,19-20,22,31H,4,11-18H2,1-3H3,(H2,29,30,32,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM25118 ((3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,...) Show SMILES CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O Show InChI InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) expressed in baculovirus infected insect cells using biotinylated-GGGGQDGKDYIVLPI peptide as substrate incubate...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545461 (CHEMBL4636935) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1ncnc(Nc2ccc(N3CCN(C)CC3)c(OC)c2)n1 Show InChI InChI=1S/C23H30N8O3S/c1-4-26-35(32,33)21-8-6-5-7-18(21)28-23-25-16-24-22(29-23)27-17-9-10-19(20(15-17)34-3)31-13-11-30(2)12-14-31/h5-10,15-16,26H,4,11-14H2,1-3H3,(H2,24,25,27,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545467 (CHEMBL4637057) Show SMILES Cl.Cl.Cl.Cl.CCNS(=O)(=O)c1ccccc1Nc1ncnc(Nc2ccc(N3CCN(C)CC3)c(OCCN3CCN(C)CC3)c2)n1 Show InChI InChI=1S/C29H42N10O3S/c1-4-32-43(40,41)27-8-6-5-7-24(27)34-29-31-22-30-28(35-29)33-23-9-10-25(39-17-13-37(3)14-18-39)26(21-23)42-20-19-38-15-11-36(2)12-16-38/h5-10,21-22,32H,4,11-20H2,1-3H3,(H2,30,31,33,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545464 (CHEMBL4644695) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1ncnc(Nc2ccc(N3CCN(C)CC3)c(OCCOC)c2)n1 Show InChI InChI=1S/C25H34N8O4S/c1-4-28-38(34,35)23-8-6-5-7-20(23)30-25-27-18-26-24(31-25)29-19-9-10-21(22(17-19)37-16-15-36-3)33-13-11-32(2)12-14-33/h5-10,17-18,28H,4,11-16H2,1-3H3,(H2,26,27,29,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545465 (CHEMBL4638978) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1ncnc(Nc2ccc(N3CCN(C)CC3)c(OCCOCCOC)c2)n1 Show InChI InChI=1S/C27H38N8O5S/c1-4-30-41(36,37)25-8-6-5-7-22(25)32-27-29-20-28-26(33-27)31-21-9-10-23(35-13-11-34(2)12-14-35)24(19-21)40-18-17-39-16-15-38-3/h5-10,19-20,30H,4,11-18H2,1-3H3,(H2,28,29,31,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50559413 (CHEMBL4756275) Show SMILES COc1cc(CCc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)cc(OC)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50559408 (CHEMBL4763773) Show SMILES COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged VEGFR2 (790 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubate...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545478 (CHEMBL4643533) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1NC(=O)c1cc(OC)nc(OC)n1 Show InChI InChI=1S/C36H47N11O6S/c1-6-38-54(49,50)31-10-8-7-9-26(31)40-33-28(41-34(48)27-22-32(52-4)43-36(42-27)53-5)23-37-35(44-33)39-24-11-12-29(30(21-24)51-3)47-15-13-25(14-16-47)46-19-17-45(2)18-20-46/h7-12,21-23,25,38H,6,13-20H2,1-5H3,(H,41,48)(H2,37,39,40,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545475 (CHEMBL4648279) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1NC(=O)c1cc(O)cc(O)c1 Show InChI InChI=1S/C36H45N9O6S/c1-4-38-52(49,50)33-8-6-5-7-29(33)40-34-30(41-35(48)24-19-27(46)22-28(47)20-24)23-37-36(42-34)39-25-9-10-31(32(21-25)51-3)45-13-11-26(12-14-45)44-17-15-43(2)16-18-44/h5-10,19-23,26,38,46-47H,4,11-18H2,1-3H3,(H,41,48)(H2,37,39,40,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50525939 (Balversa | Erdafitinib | Jnj-42756493) Show SMILES COc1cc(OC)cc(c1)N(CCNC(C)C)c1ccc2ncc(nc2c1)-c1cnn(C)c1 Show InChI InChI=1S/C25H30N6O2/c1-17(2)26-8-9-31(20-10-21(32-4)13-22(11-20)33-5)19-6-7-23-24(12-19)29-25(15-27-23)18-14-28-30(3)16-18/h6-7,10-17,26H,8-9H2,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6-tagged VEGFR2 (790 to end residues) expressed in baculovirus infected Sf21 cells using FLT3 peptide as substrate ...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50545469 (CHEMBL4635284) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1-c1cc(OC)cc(OC)c1 Show InChI InChI=1S/C37H48N8O5S/c1-6-39-51(46,47)35-10-8-7-9-32(35)41-36-31(26-21-29(48-3)24-30(22-26)49-4)25-38-37(42-36)40-27-11-12-33(34(23-27)50-5)45-15-13-28(14-16-45)44-19-17-43(2)18-20-44/h7-12,21-25,28,39H,6,13-20H2,1-5H3,(H2,38,40,41,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human VEGFR2 cytoplasmic domain (790-1356 end amino acid residue) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545474 (CHEMBL4635626) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1NC(=O)c1cccc(OC)c1OC Show InChI InChI=1S/C38H49N9O6S/c1-6-40-54(49,50)34-13-8-7-11-29(34)42-36-30(43-37(48)28-10-9-12-32(51-3)35(28)53-5)25-39-38(44-36)41-26-14-15-31(33(24-26)52-4)47-18-16-27(17-19-47)46-22-20-45(2)21-23-46/h7-15,24-25,27,40H,6,16-23H2,1-5H3,(H,43,48)(H2,39,41,42,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50545460 (CHEMBL4641667) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1ncnc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)n1 Show InChI InChI=1S/C28H39N9O3S/c1-4-31-41(38,39)26-8-6-5-7-23(26)33-28-30-20-29-27(34-28)32-21-9-10-24(25(19-21)40-3)37-13-11-22(12-14-37)36-17-15-35(2)16-18-36/h5-10,19-20,22,31H,4,11-18H2,1-3H3,(H2,29,30,32,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR1 cytoplasmic domain (398-822 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50559410 (CHEMBL4741510) Show SMILES COc1cc(COc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)cc(OC)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116019 BindingDB Entry DOI: 10.7270/Q2QN6BGC
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50545473 (CHEMBL4647945) Show SMILES CCNS(=O)(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)ncc1NC(=O)c1cc(OC)ccc1OC Show InChI InChI=1S/C38H49N9O6S/c1-6-40-54(49,50)35-10-8-7-9-30(35)42-36-31(43-37(48)29-24-28(51-3)12-14-33(29)52-4)25-39-38(44-36)41-26-11-13-32(34(23-26)53-5)47-17-15-27(16-18-47)46-21-19-45(2)20-22-46/h7-14,23-25,27,40H,6,15-22H2,1-5H3,(H,43,48)(H2,39,41,42,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human FGFR3 cytoplasmic domain (436-806 end amino acids residues) expressed in baculovirus expression system prei...				Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115453 BindingDB Entry DOI: 10.7270/Q20V8HCD
					More data for this Ligand-Target Pair

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