Compile Data Set for Download or QSAR

Found 179 hits with Last Name = 'marco' and Initial = 'i'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359421 (CHEMBL1926735) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNC[C@@H]1CCc2ccccc2O1 |r| Show InChI InChI=1S/C20H27N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-2,6,8,16,21,24H,3-5,7,9-14H2/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359428 (CHEMBL1926759) Show SMILES Oc1csc(=O)n1CCCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C19H26N2O3S/c22-18-14-25-19(23)21(18)12-6-2-1-5-11-20-13-16-10-9-15-7-3-4-8-17(15)24-16/h3-4,7-8,14,16,20,22H,1-2,5-6,9-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359422 (CHEMBL1926734) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNC[C@H]1CCc2ccccc2O1 |r| Show InChI InChI=1S/C20H27N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-2,6,8,16,21,24H,3-5,7,9-14H2/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359420 (CHEMBL1926744) Show SMILES Oc1c2CCCCn2c(=O)n1CCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C21H29N3O3/c25-20-18-8-3-5-13-23(18)21(26)24(20)14-6-4-12-22-15-17-11-10-16-7-1-2-9-19(16)27-17/h1-2,7,9,17,22,25H,3-6,8,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359429 (CHEMBL1926758) Show SMILES Oc1csc(=O)n1CCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C18H24N2O3S/c21-17-13-24-18(22)20(17)11-5-1-4-10-19-12-15-9-8-14-6-2-3-7-16(14)23-15/h2-3,6-7,13,15,19,21H,1,4-5,8-12H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359436 (CHEMBL1926751) Show SMILES Oc1c2CCCn2c(=O)n1CCCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C22H31N3O3/c26-21-19-9-7-15-24(19)22(27)25(21)14-6-2-1-5-13-23-16-18-12-11-17-8-3-4-10-20(17)28-18/h3-4,8,10,18,23,26H,1-2,5-7,9,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50359436 (CHEMBL1926751) Show SMILES Oc1c2CCCn2c(=O)n1CCCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C22H31N3O3/c26-21-19-9-7-15-24(19)22(27)25(21)14-6-2-1-5-13-23-16-18-12-11-17-8-3-4-10-20(17)28-18/h3-4,8,10,18,23,26H,1-2,5-7,9,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from 5HT7 receptor in Sprague-Dawley albinus rat hypothalamic membranes after 120 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50359425 (CHEMBL1926730) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNCc1ccc2ccccc2c1 Show InChI InChI=1S/C21H25N3O2/c25-20-19-8-5-13-23(19)21(26)24(20)12-4-3-11-22-15-16-9-10-17-6-1-2-7-18(17)14-16/h1-2,6-7,9-10,14,22,25H,3-5,8,11-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from 5HT7 receptor in Sprague-Dawley albinus rat hypothalamic membranes after 120 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359438 (CHEMBL1926750) Show SMILES Oc1c2CCCn2c(=O)n1CCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C19H25N3O3/c23-18-16-6-3-11-21(16)19(24)22(18)12-4-10-20-13-15-9-8-14-5-1-2-7-17(14)25-15/h1-2,5,7,15,20,23H,3-4,6,8-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359423 (CHEMBL1926732) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNCc1ccc2ccccc2n1 Show InChI InChI=1S/C20H24N4O2/c25-19-18-8-5-13-23(18)20(26)24(19)12-4-3-11-21-14-16-10-9-15-6-1-2-7-17(15)22-16/h1-2,6-7,9-10,21,25H,3-5,8,11-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50132532 (2-[4-(2-Methoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...) Show SMILES COc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |THB:22:23:29.30:27.26,(10.09,-2.78,;10.85,-4.13,;10.08,-5.44,;10.82,-6.78,;10.05,-8.12,;8.51,-8.1,;7.75,-6.76,;8.54,-5.44,;7.78,-4.1,;7.6,-2.78,;8.49,-1.29,;7.3,-.31,;6.53,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.79,;1.27,2.56,;1.27,4.12,;2.59,4.89,;-.07,4.87,;-1.41,4.09,;-1.32,2.67,;-2.6,3.51,;-4.22,3.07,;-4.21,4.47,;-2.65,4.91,;-2.35,6.52,;-2.07,5.35,;2.61,1.79,;4.08,2.28,;7.5,-1.54,;6.6,-3.12,)| Show InChI InChI=1S/C27H34N6O2/c1-35-24-8-3-2-7-23(24)33-15-13-32(14-16-33)18-25-28-21-6-4-5-20(26(21)30-25)27(34)29-22-17-31-11-9-19(22)10-12-31/h2-8,19,22H,9-18H2,1H3,(H,28,30)(H,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (RAT)	BDBM50359427 (CHEMBL1926760) Show SMILES Oc1csc(=O)n1CCCCCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C21H30N2O3S/c24-20-16-27-21(25)23(20)14-8-4-2-1-3-7-13-22-15-18-12-11-17-9-5-6-10-19(17)26-18/h5-6,9-10,16,18,22,24H,1-4,7-8,11-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-LY278584 from 5HT3 receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 30 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50359427 (CHEMBL1926760) Show SMILES Oc1csc(=O)n1CCCCCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C21H30N2O3S/c24-20-16-27-21(25)23(20)14-8-4-2-1-3-7-13-22-15-18-12-11-17-9-5-6-10-19(17)26-18/h5-6,9-10,16,18,22,24H,1-4,7-8,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from 5HT7 receptor in Sprague-Dawley albinus rat hypothalamic membranes after 120 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359427 (CHEMBL1926760) Show SMILES Oc1csc(=O)n1CCCCCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C21H30N2O3S/c24-20-16-27-21(25)23(20)14-8-4-2-1-3-7-13-22-15-18-12-11-17-9-5-6-10-19(17)26-18/h5-6,9-10,16,18,22,24H,1-4,7-8,11-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359437 (CHEMBL1926686) Show SMILES Oc1c2CCCn2c(=O)n1CCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C21H29N3O3/c25-20-18-8-6-14-23(18)21(26)24(20)13-5-1-4-12-22-15-17-11-10-16-7-2-3-9-19(16)27-17/h2-3,7,9,17,22,25H,1,4-6,8,10-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359416 (CHEMBL1926748) Show SMILES Oc1c2CSCn2c(=O)n1CCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C19H25N3O3S/c23-18-16-12-26-13-22(16)19(24)21(18)10-4-3-9-20-11-15-8-7-14-5-1-2-6-17(14)25-15/h1-2,5-6,15,20,23H,3-4,7-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50132533 (2-[4-(2-Butoxy-phenyl)-piperazin-1-ylmethyl]-1H-be...) Show SMILES CCCCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |THB:25:26:32.33:30.29,(14.62,-7.89,;14.22,-6.39,;12.73,-6,;12.34,-4.52,;10.85,-4.13,;10.08,-5.44,;10.82,-6.78,;10.04,-8.12,;8.51,-8.09,;7.75,-6.76,;8.54,-5.44,;7.78,-4.1,;7.6,-2.78,;8.49,-1.29,;7.3,-.31,;6.53,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.79,;1.27,2.56,;1.27,4.12,;2.59,4.89,;-.07,4.87,;-1.41,4.09,;-1.32,2.67,;-2.6,3.51,;-4.22,3.07,;-4.21,4.47,;-2.65,4.91,;-2.35,6.52,;-2.07,5.35,;2.61,1.79,;4.08,2.28,;7.5,-1.54,;6.6,-3.12,)| Show InChI InChI=1S/C30H40N6O2/c1-2-3-19-38-27-10-5-4-9-26(27)36-17-15-35(16-18-36)21-28-31-24-8-6-7-23(29(24)33-28)30(37)32-25-20-34-13-11-22(25)12-14-34/h4-10,22,25H,2-3,11-21H2,1H3,(H,31,33)(H,32,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359439 (CHEMBL1926749) Show SMILES Oc1csc(=O)n1CCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C17H22N2O3S/c20-16-12-23-17(21)19(16)10-4-3-9-18-11-14-8-7-13-5-1-2-6-15(13)22-14/h1-2,5-6,12,14,18,20H,3-4,7-11H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50132536 (2-[4-(2-Ethoxy-phenyl)-piperazin-1-ylmethyl]-1H-be...) Show SMILES CCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |THB:23:24:30.31:28.27,(8.56,-2.78,;10.1,-2.78,;10.85,-4.13,;10.08,-5.44,;10.83,-6.79,;10.05,-8.12,;8.51,-8.1,;7.75,-6.76,;8.54,-5.44,;7.79,-4.1,;7.6,-2.78,;8.5,-1.29,;7.31,-.31,;6.54,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.8,;1.27,2.57,;1.27,4.12,;2.6,4.89,;-.07,4.87,;-1.41,4.1,;-1.32,2.67,;-2.6,3.51,;-4.22,3.07,;-4.21,4.48,;-2.65,4.91,;-2.35,6.52,;-2.07,5.36,;2.61,1.8,;4.08,2.28,;7.51,-1.54,;6.6,-3.12,)| Show InChI InChI=1S/C28H36N6O2/c1-2-36-25-9-4-3-8-24(25)34-16-14-33(15-17-34)19-26-29-22-7-5-6-21(27(22)31-26)28(35)30-23-18-32-12-10-20(23)11-13-32/h3-9,20,23H,2,10-19H2,1H3,(H,29,31)(H,30,35)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50132540 (2-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-be...) Show SMILES Clc1cccc(c1)N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |THB:21:22:28.29:26.25,(12.36,-6.78,;10.82,-6.78,;10.05,-8.12,;8.51,-8.1,;7.75,-6.76,;8.54,-5.44,;10.08,-5.44,;7.79,-4.1,;7.6,-2.78,;8.49,-1.29,;7.3,-.31,;6.53,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.79,;1.27,2.56,;1.27,4.12,;2.6,4.89,;-.07,4.87,;-1.41,4.09,;-1.32,2.67,;-2.6,3.51,;-4.22,3.07,;-4.21,4.48,;-2.65,4.91,;-2.35,6.52,;-2.07,5.35,;2.61,1.79,;4.08,2.28,;7.51,-1.54,;6.6,-3.12,)| Show InChI InChI=1S/C26H31ClN6O/c27-19-3-1-4-20(15-19)33-13-11-32(12-14-33)17-24-28-22-6-2-5-21(25(22)30-24)26(34)29-23-16-31-9-7-18(23)8-10-31/h1-6,15,18,23H,7-14,16-17H2,(H,28,30)(H,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359417 (CHEMBL1926747) Show SMILES Oc1c2CCSn2c(=O)n1CCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C19H25N3O3S/c23-18-16-9-12-26-22(16)19(24)21(18)11-4-3-10-20-13-15-8-7-14-5-1-2-6-17(14)25-15/h1-2,5-6,15,20,23H,3-4,7-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359419 (CHEMBL1926745) Show SMILES O=C1CN(CCCCNCC2CCc3ccccc3O2)C(=O)C2CCCN12 Show InChI InChI=1S/C21H29N3O3/c25-20-15-23(21(26)18-7-5-13-24(18)20)12-4-3-11-22-14-17-10-9-16-6-1-2-8-19(16)27-17/h1-2,6,8,17-18,22H,3-5,7,9-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50132539 (2-(4-Phenyl-piperazin-1-ylmethyl)-1H-benzoimidazol...) Show SMILES O=C(NC1CN2CCC1CC2)c1cccc2nc(CN3CCN(CC3)c3ccccc3)[nH]c12 |TLB:2:3:9.10:7.6,(2.66,3.49,;1.33,2.71,;-.02,3.48,;-1.35,2.7,;-1.26,1.28,;-2.54,2.12,;-2,3.96,;-2.29,5.13,;-2.59,3.52,;-4.15,3.08,;-4.17,1.67,;1.34,1.17,;.01,.4,;.01,-1.15,;1.34,-1.92,;2.67,-1.15,;4.14,-1.63,;5.06,-.37,;6.6,-.37,;7.37,-1.71,;7.57,-2.94,;6.66,-4.53,;7.85,-5.51,;7.66,-4.18,;8.56,-2.69,;8.61,-6.84,;10.15,-6.84,;10.9,-8.17,;10.11,-9.53,;8.57,-9.5,;7.82,-8.17,;4.14,.88,;2.67,.4,)| Show InChI InChI=1S/C26H32N6O/c33-26(28-23-17-30-11-9-19(23)10-12-30)21-7-4-8-22-25(21)29-24(27-22)18-31-13-15-32(16-14-31)20-5-2-1-3-6-20/h1-8,19,23H,9-18H2,(H,27,29)(H,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50132535 (2-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-ylmeth...) Show SMILES FC(F)(F)c1cccc(c1)N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |TLB:24:25:31.32:29.28,(13.78,-6.79,;12.36,-6.79,;13.38,-8.04,;13.39,-5.55,;10.82,-6.78,;10.05,-8.12,;8.51,-8.1,;7.75,-6.76,;8.54,-5.44,;10.08,-5.44,;7.79,-4.1,;6.6,-3.12,;7.51,-1.54,;7.3,-.31,;6.54,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.79,;1.27,2.56,;1.27,4.12,;2.6,4.89,;-.07,4.87,;-1.41,4.09,;-1.32,2.67,;-2.6,3.51,;-2.07,5.35,;-2.35,6.52,;-2.65,4.91,;-4.21,4.48,;-4.22,3.07,;2.61,1.79,;4.08,2.28,;8.49,-1.29,;7.6,-2.78,)| Show InChI InChI=1S/C27H31F3N6O/c28-27(29,30)19-3-1-4-20(15-19)36-13-11-35(12-14-36)17-24-31-22-6-2-5-21(25(22)33-24)26(37)32-23-16-34-9-7-18(23)8-10-34/h1-6,15,18,23H,7-14,16-17H2,(H,31,33)(H,32,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50132537 (2-(4-Benzo[1,3]dioxol-5-yl-piperazin-1-ylmethyl)-1...) Show SMILES O=C(NC1CN2CCC1CC2)c1cccc2nc(CN3CCN(CC3)c3ccc4OCOc4c3)[nH]c12 |TLB:2:3:9.10:7.6,(2.94,4.77,;1.62,4,;.28,4.75,;-1.06,3.98,;-.97,2.56,;-2.25,3.39,;-1.72,5.24,;-2,6.4,;-2.3,4.79,;-3.86,4.36,;-3.87,2.95,;1.62,2.45,;.29,1.68,;.29,.13,;1.62,-.64,;2.96,.13,;4.43,-.35,;5.35,.91,;6.88,.91,;7.65,-.43,;7.85,-1.65,;6.95,-3.24,;8.13,-4.22,;7.95,-2.9,;8.84,-1.41,;8.89,-5.55,;8.1,-6.88,;8.86,-8.21,;10.4,-8.23,;11.43,-9.38,;12.83,-8.76,;12.69,-7.23,;11.17,-6.9,;10.43,-5.55,;4.43,2.16,;2.96,1.68,)| Show InChI InChI=1S/C27H32N6O3/c34-27(29-22-15-31-8-6-18(22)7-9-31)20-2-1-3-21-26(20)30-25(28-21)16-32-10-12-33(13-11-32)19-4-5-23-24(14-19)36-17-35-23/h1-5,14,18,22H,6-13,15-17H2,(H,28,30)(H,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50132538 (2-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...) Show SMILES CCCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |THB:24:25:31.32:29.28,(10.11,-.12,;10.88,-1.45,;10.1,-2.78,;10.85,-4.13,;10.08,-5.44,;10.83,-6.79,;10.05,-8.12,;8.51,-8.1,;7.75,-6.76,;8.54,-5.44,;7.79,-4.1,;7.6,-2.78,;8.5,-1.29,;7.31,-.31,;6.54,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.8,;1.27,2.57,;1.27,4.12,;2.6,4.89,;-.07,4.87,;-1.41,4.1,;-1.32,2.67,;-2.6,3.51,;-4.22,3.07,;-4.21,4.48,;-2.65,4.91,;-2.35,6.52,;-2.07,5.36,;2.61,1.8,;4.08,2.28,;7.51,-1.54,;6.6,-3.13,)| Show InChI InChI=1S/C29H38N6O2/c1-2-18-37-26-9-4-3-8-25(26)35-16-14-34(15-17-35)20-27-30-23-7-5-6-22(28(23)32-27)29(36)31-24-19-33-12-10-21(24)11-13-33/h3-9,21,24H,2,10-20H2,1H3,(H,30,32)(H,31,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359434 (CHEMBL1926753) Show SMILES Oc1c2CCCn2c(=O)n1C\C=C\CNCC1CCc2ccccc2O1 Show InChI InChI=1S/C20H25N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-4,6,8,16,21,24H,5,7,9-14H2/b4-3+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50132536 (2-[4-(2-Ethoxy-phenyl)-piperazin-1-ylmethyl]-1H-be...) Show SMILES CCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |THB:23:24:30.31:28.27,(8.56,-2.78,;10.1,-2.78,;10.85,-4.13,;10.08,-5.44,;10.83,-6.79,;10.05,-8.12,;8.51,-8.1,;7.75,-6.76,;8.54,-5.44,;7.79,-4.1,;7.6,-2.78,;8.5,-1.29,;7.31,-.31,;6.54,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.8,;1.27,2.57,;1.27,4.12,;2.6,4.89,;-.07,4.87,;-1.41,4.1,;-1.32,2.67,;-2.6,3.51,;-4.22,3.07,;-4.21,4.48,;-2.65,4.91,;-2.35,6.52,;-2.07,5.36,;2.61,1.8,;4.08,2.28,;7.51,-1.54,;6.6,-3.12,)| Show InChI InChI=1S/C28H36N6O2/c1-2-36-25-9-4-3-8-24(25)34-16-14-33(15-17-34)19-26-29-22-7-5-6-21(27(22)31-26)28(35)30-23-18-32-12-10-20(23)11-13-32/h3-9,20,23H,2,10-19H2,1H3,(H,29,31)(H,30,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359431 (CHEMBL1926756) Show SMILES Oc1c2CCCn2c(=O)n1Cc1ccc(CNCC2CCc3ccccc3O2)cc1 Show InChI InChI=1S/C24H27N3O3/c28-23-21-5-3-13-26(21)24(29)27(23)16-18-9-7-17(8-10-18)14-25-15-20-12-11-19-4-1-2-6-22(19)30-20/h1-2,4,6-10,20,25,28H,3,5,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359426 (CHEMBL1926729) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNCCc1cccc2ccccc12 Show InChI InChI=1S/C22H27N3O2/c26-21-20-11-6-16-24(20)22(27)25(21)15-4-3-13-23-14-12-18-9-5-8-17-7-1-2-10-19(17)18/h1-2,5,7-10,23,26H,3-4,6,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50132534 (2-(4-Naphthalen-1-yl-piperazin-1-ylmethyl)-1H-benz...) Show SMILES O=C(NC1CN2CCC1CC2)c1cccc2nc(CN3CCN(CC3)c3cccc4ccccc34)[nH]c12 |THB:2:3:7.6:9.10,(2.95,4.78,;1.62,4.01,;.28,4.76,;-1.07,3.98,;-.97,2.56,;-2.26,3.4,;-3.87,2.96,;-3.87,4.36,;-2.3,4.8,;-2,6.41,;-1.72,5.24,;1.62,2.45,;.29,1.68,;.29,.13,;1.62,-.64,;2.96,.13,;4.43,-.35,;5.35,.91,;6.89,.91,;7.66,-.43,;7.86,-1.66,;6.95,-3.24,;8.14,-4.22,;7.96,-2.9,;8.85,-1.41,;8.9,-5.56,;8.1,-6.88,;8.87,-8.22,;10.41,-8.24,;11.18,-6.91,;12.72,-6.91,;13.49,-5.6,;12.74,-4.25,;11.21,-4.25,;10.44,-5.56,;4.43,2.16,;2.96,1.68,)| Show InChI InChI=1S/C30H34N6O/c37-30(32-26-19-34-13-11-22(26)12-14-34)24-8-4-9-25-29(24)33-28(31-25)20-35-15-17-36(18-16-35)27-10-3-6-21-5-1-2-7-23(21)27/h1-10,22,26H,11-20H2,(H,31,33)(H,32,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50132531 (2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |TLB:24:25:31.32:29.28,(12.75,-6,;12.35,-4.53,;13.42,-3.43,;10.86,-4.13,;10.09,-5.44,;10.83,-6.79,;10.06,-8.13,;8.52,-8.1,;7.75,-6.77,;8.55,-5.44,;7.79,-4.11,;6.6,-3.13,;7.51,-1.54,;7.31,-.31,;6.54,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.8,;1.27,2.57,;1.27,4.12,;2.6,4.89,;-.07,4.88,;-1.42,4.1,;-1.32,2.68,;-2.61,3.52,;-2.07,5.36,;-2.35,6.52,;-2.65,4.91,;-4.21,4.48,;-4.22,3.07,;2.61,1.8,;4.08,2.28,;8.5,-1.29,;7.61,-2.78,)| Show InChI InChI=1S/C29H38N6O2/c1-20(2)37-26-9-4-3-8-25(26)35-16-14-34(15-17-35)19-27-30-23-7-5-6-22(28(23)32-27)29(36)31-24-18-33-12-10-21(24)11-13-33/h3-9,20-21,24H,10-19H2,1-2H3,(H,30,32)(H,31,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359418 (CHEMBL1926746) Show SMILES O=C1CN(CCCCNCC2CCc3ccccc3O2)C(=O)C2CCCCN12 Show InChI InChI=1S/C22H31N3O3/c26-21-16-24(22(27)19-8-3-5-14-25(19)21)13-6-4-12-23-15-18-11-10-17-7-1-2-9-20(17)28-18/h1-2,7,9,18-19,23H,3-6,8,10-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359421 (CHEMBL1926735) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNC[C@@H]1CCc2ccccc2O1 |r| Show InChI InChI=1S/C20H27N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-2,6,8,16,21,24H,3-5,7,9-14H2/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50359430 (CHEMBL1926757) Show SMILES Oc1c2CCCn2c(=O)n1Cc1cccc(CNCC2CCc3ccccc3O2)c1 Show InChI InChI=1S/C24H27N3O3/c28-23-21-8-4-12-26(21)24(29)27(23)16-18-6-3-5-17(13-18)14-25-15-20-11-10-19-7-1-2-9-22(19)30-20/h1-3,5-7,9,13,20,25,28H,4,8,10-12,14-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in Sprague-Dawley albinus rat striatal membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50359422 (CHEMBL1926734) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNC[C@H]1CCc2ccccc2O1 |r| Show InChI InChI=1S/C20H27N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-2,6,8,16,21,24H,3-5,7,9-14H2/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from 5HT7 receptor in Sprague-Dawley albinus rat hypothalamic membranes after 120 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359430 (CHEMBL1926757) Show SMILES Oc1c2CCCn2c(=O)n1Cc1cccc(CNCC2CCc3ccccc3O2)c1 Show InChI InChI=1S/C24H27N3O3/c28-23-21-8-4-12-26(21)24(29)27(23)16-18-6-3-5-17(13-18)14-25-15-20-11-10-19-7-1-2-9-22(19)30-20/h1-3,5-7,9,13,20,25,28H,4,8,10-12,14-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359424 (CHEMBL1926731) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNCCc1ccc2ccccc2c1 Show InChI InChI=1S/C22H27N3O2/c26-21-20-8-5-15-24(20)22(27)25(21)14-4-3-12-23-13-11-17-9-10-18-6-1-2-7-19(18)16-17/h1-2,6-7,9-10,16,23,26H,3-5,8,11-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50132533 (2-[4-(2-Butoxy-phenyl)-piperazin-1-ylmethyl]-1H-be...) Show SMILES CCCCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |THB:25:26:32.33:30.29,(14.62,-7.89,;14.22,-6.39,;12.73,-6,;12.34,-4.52,;10.85,-4.13,;10.08,-5.44,;10.82,-6.78,;10.04,-8.12,;8.51,-8.09,;7.75,-6.76,;8.54,-5.44,;7.78,-4.1,;7.6,-2.78,;8.49,-1.29,;7.3,-.31,;6.53,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.79,;1.27,2.56,;1.27,4.12,;2.59,4.89,;-.07,4.87,;-1.41,4.09,;-1.32,2.67,;-2.6,3.51,;-4.22,3.07,;-4.21,4.47,;-2.65,4.91,;-2.35,6.52,;-2.07,5.35,;2.61,1.79,;4.08,2.28,;7.5,-1.54,;6.6,-3.12,)| Show InChI InChI=1S/C30H40N6O2/c1-2-3-19-38-27-10-5-4-9-26(27)36-17-15-35(16-18-36)21-28-31-24-8-6-7-23(29(24)33-28)30(37)32-25-20-34-13-11-22(25)12-14-34/h4-10,22,25H,2-3,11-21H2,1H3,(H,31,33)(H,32,37)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359425 (CHEMBL1926730) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNCc1ccc2ccccc2c1 Show InChI InChI=1S/C21H25N3O2/c25-20-19-8-5-13-23(19)21(26)24(20)12-4-3-11-22-15-16-9-10-17-6-1-2-7-18(17)14-16/h1-2,6-7,9-10,14,22,25H,3-5,8,11-13,15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50132538 (2-[4-(2-Propoxy-phenyl)-piperazin-1-ylmethyl]-1H-b...) Show SMILES CCCOc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |THB:24:25:31.32:29.28,(10.11,-.12,;10.88,-1.45,;10.1,-2.78,;10.85,-4.13,;10.08,-5.44,;10.83,-6.79,;10.05,-8.12,;8.51,-8.1,;7.75,-6.76,;8.54,-5.44,;7.79,-4.1,;7.6,-2.78,;8.5,-1.29,;7.31,-.31,;6.54,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.8,;1.27,2.57,;1.27,4.12,;2.6,4.89,;-.07,4.87,;-1.41,4.1,;-1.32,2.67,;-2.6,3.51,;-4.22,3.07,;-4.21,4.48,;-2.65,4.91,;-2.35,6.52,;-2.07,5.36,;2.61,1.8,;4.08,2.28,;7.51,-1.54,;6.6,-3.13,)| Show InChI InChI=1S/C29H38N6O2/c1-2-18-37-26-9-4-3-8-25(26)35-16-14-34(15-17-35)20-27-30-23-7-5-6-22(28(23)32-27)29(36)31-24-19-33-12-10-21(24)11-13-33/h3-9,21,24H,2,10-20H2,1H3,(H,30,32)(H,31,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-hydroxytryptamine 1A receptor of rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50359438 (CHEMBL1926750) Show SMILES Oc1c2CCCn2c(=O)n1CCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C19H25N3O3/c23-18-16-6-3-11-21(16)19(24)22(18)12-4-10-20-13-15-9-8-14-5-1-2-7-17(14)25-15/h1-2,5,7,15,20,23H,3-4,6,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from 5HT7 receptor in Sprague-Dawley albinus rat hypothalamic membranes after 120 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (RAT)	BDBM50359427 (CHEMBL1926760) Show SMILES Oc1csc(=O)n1CCCCCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C21H30N2O3S/c24-20-16-27-21(25)23(20)14-8-4-2-1-3-7-13-22-15-18-12-11-17-9-5-6-10-19(17)26-18/h5-6,9-10,16,18,22,24H,1-4,7-8,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]GR113808 from 5HT4 receptor in Sprague-Dawley albinus rat striatal membranes after 30 mins by scintillation counting				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50132531 (2-[4-(2-Isopropoxy-phenyl)-piperazin-1-ylmethyl]-1...) Show SMILES CC(C)Oc1ccccc1N1CCN(Cc2nc3cccc(C(=O)NC4CN5CCC4CC5)c3[nH]2)CC1 |TLB:24:25:31.32:29.28,(12.75,-6,;12.35,-4.53,;13.42,-3.43,;10.86,-4.13,;10.09,-5.44,;10.83,-6.79,;10.06,-8.13,;8.52,-8.1,;7.75,-6.77,;8.55,-5.44,;7.79,-4.11,;6.6,-3.13,;7.51,-1.54,;7.31,-.31,;6.54,1.03,;5,1.03,;4.08,-.23,;2.61,.25,;1.27,-.52,;-.06,.25,;-.06,1.8,;1.27,2.57,;1.27,4.12,;2.6,4.89,;-.07,4.88,;-1.42,4.1,;-1.32,2.68,;-2.61,3.52,;-2.07,5.36,;-2.35,6.52,;-2.65,4.91,;-4.21,4.48,;-4.22,3.07,;2.61,1.8,;4.08,2.28,;8.5,-1.29,;7.61,-2.78,)| Show InChI InChI=1S/C29H38N6O2/c1-20(2)37-26-9-4-3-8-25(26)35-16-14-34(15-17-35)19-27-30-23-7-5-6-22(28(23)32-27)29(36)31-24-18-33-12-10-21(24)11-13-33/h3-9,20-21,24H,10-19H2,1-2H3,(H,30,32)(H,31,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity for 5-HT3 receptor by displacement of [3H]-LY 278584 in rat cerebral cortex membranes				Bioorg Med Chem Lett 13: 3177-80 (2003) BindingDB Entry DOI: 10.7270/Q2GH9HCP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50359434 (CHEMBL1926753) Show SMILES Oc1c2CCCn2c(=O)n1C\C=C\CNCC1CCc2ccccc2O1 Show InChI InChI=1S/C20H25N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-4,6,8,16,21,24H,5,7,9-14H2/b4-3+	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from 5HT7 receptor in Sprague-Dawley albinus rat hypothalamic membranes after 120 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50359420 (CHEMBL1926744) Show SMILES Oc1c2CCCCn2c(=O)n1CCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C21H29N3O3/c25-20-18-8-3-5-13-23(18)21(26)24(20)14-6-4-12-22-15-17-11-10-16-7-1-2-9-19(16)27-17/h1-2,7,9,17,22,25H,3-6,8,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from 5HT7 receptor in Sprague-Dawley albinus rat hypothalamic membranes after 120 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50359421 (CHEMBL1926735) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNC[C@@H]1CCc2ccccc2O1 |r| Show InChI InChI=1S/C20H27N3O3/c24-19-17-7-5-13-22(17)20(25)23(19)12-4-3-11-21-14-16-10-9-15-6-1-2-8-18(15)26-16/h1-2,6,8,16,21,24H,3-5,7,9-14H2/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from 5HT7 receptor in Sprague-Dawley albinus rat hypothalamic membranes after 120 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50359424 (CHEMBL1926731) Show SMILES Oc1c2CCCn2c(=O)n1CCCCNCCc1ccc2ccccc2c1 Show InChI InChI=1S/C22H27N3O2/c26-21-20-8-5-15-24(20)22(27)25(21)14-4-3-12-23-13-11-17-9-10-18-6-1-2-7-19(18)16-17/h1-2,6-7,9-10,16,23,26H,3-5,8,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from 5HT7 receptor in Sprague-Dawley albinus rat hypothalamic membranes after 120 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM50359428 (CHEMBL1926759) Show SMILES Oc1csc(=O)n1CCCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C19H26N2O3S/c22-18-14-25-19(23)21(18)12-6-2-1-5-11-20-13-16-10-9-15-7-3-4-8-17(15)24-16/h3-4,7-8,14,16,20,22H,1-2,5-6,9-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-5-CT from 5HT7 receptor in Sprague-Dawley albinus rat hypothalamic membranes after 120 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359435 (CHEMBL1926752) Show SMILES Oc1c2CCCn2c(=O)n1CCCCCCCCNCC1CCc2ccccc2O1 Show InChI InChI=1S/C24H35N3O3/c28-23-21-11-9-17-26(21)24(29)27(23)16-8-4-2-1-3-7-15-25-18-20-14-13-19-10-5-6-12-22(19)30-20/h5-6,10,12,20,25,28H,1-4,7-9,11,13-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in Sprague-Dawley albinus rat cerebral cortex membranes after 15 mins				J Med Chem 54: 7986-99 (2011) Article DOI: 10.1021/jm2007886 BindingDB Entry DOI: 10.7270/Q2R49R61
					More data for this Ligand-Target Pair

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