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Compile Data Set for Download or QSAR

Found 4 hits with Last Name = 'takasaki' and Initial = 'i'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Pituitary adenylate cyclase-activating polypeptide type I receptor


(Homo sapiens (Human))
BDBM50550811
PNG
(CHEMBL4740931)
Show SMILES Clc1cccc2c(n[nH]c12)N1CC(CC1=O)C(=O)NCCc1c[nH]cn1
PDB

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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a<0.0100n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at PAC1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced inhibition of CREB phosphorylati...


Citation and Details

Article DOI: 10.1016/j.ejmech.2019.111902
BindingDB Entry DOI: 10.7270/Q28K7DPJ
More data for this
Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor


(Homo sapiens (Human))
BDBM50596676
PNG
(CHEMBL5203375)
Show SMILES Nc1nc2NC(=O)CC(c3cccc(OC(F)(F)F)c3)c2c(=O)[nH]1
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.110n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114160
BindingDB Entry DOI: 10.7270/Q2CV4NRW
More data for this
Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor


(Homo sapiens (Human))
BDBM50550810
PNG
(CHEMBL4757203)
Show SMILES O=C(NCCc1c[nH]cn1)C1CN(C(=O)C1)c1n[nH]c2ccccc12
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.182n/an/an/an/an/an/a


TBA

Assay Description
Antagonist activity at PAC1 receptor (unknown origin) expressed in CHO cells assessed as inhibition of PACAP-induced inhibition of CREB phosphorylati...


Citation and Details

Article DOI: 10.1016/j.ejmech.2019.111902
BindingDB Entry DOI: 10.7270/Q28K7DPJ
More data for this
Ligand-Target Pair
Pituitary adenylate cyclase-activating polypeptide type I receptor


(Homo sapiens (Human))
BDBM50596675
PNG
(CHEMBL5208587)
Show SMILES COc1cc(ccc1OCC=C)C1CC(=O)Nc2nc(N)[nH]c(=O)c12
PDB

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MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.5n/an/an/an/an/an/a


TBA



Citation and Details

Article DOI: 10.1016/j.ejmech.2022.114160
BindingDB Entry DOI: 10.7270/Q2CV4NRW
More data for this
Ligand-Target Pair