Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099052![]() (CHEMBL3344150) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.32E+3 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongin-C (Homo sapiens (Human)) | BDBM50463159![]() (CHEMBL4241500) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 6.70 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6 tagged VHL (54 to 213 residues)/ELoC (17 to 112 residues)/EloB (1 to 120 residues) (unknown origin) complex expre... | J Med Chem 61: 7387-7393 (2018) Article DOI: 10.1021/acs.jmedchem.8b00842 BindingDB Entry DOI: 10.7270/Q2639SCC | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099054![]() (CHEMBL3344089) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 9.52E+3 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099055![]() (CHEMBL3344088) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 291 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099056![]() (CHEMBL3344087) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 588 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099057![]() (CHEMBL3344086) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 943 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099058![]() (CHEMBL3344084) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 384 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099059![]() (CHEMBL3344085) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099060![]() (CHEMBL3344083) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 714 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099061![]() (CHEMBL3344082) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 826 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099062![]() (CHEMBL3344081 | US10730870, Example 3 | US11512083...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 185 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099063![]() (CHEMBL3344080) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 6.53E+3 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099144![]() (CHEMBL3344079) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 3.27E+3 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099145![]() (CHEMBL3344078) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 7.09E+3 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099146![]() (CHEMBL3344077) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099147![]() (CHEMBL3343404) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 2.22E+4 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50446138![]() (CHEMBL3108881) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50446132![]() (CHEMBL3108874) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 4.30E+6 | n/a | n/a | n/a | n/a | n/a |
University of Cambridge Curated by ChEMBL | Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis | ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50446133![]() (CHEMBL3108875) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.70E+6 | n/a | n/a | n/a | n/a | n/a |
University of Cambridge Curated by ChEMBL | Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis | ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50446134![]() (CHEMBL3108877) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 4.90E+6 | n/a | n/a | n/a | n/a | n/a |
University of Cambridge Curated by ChEMBL | Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis | ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50446135![]() (CHEMBL3108879) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 2.40E+5 | n/a | n/a | n/a | n/a | n/a |
University of Cambridge Curated by ChEMBL | Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis | ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50446136![]() (CHEMBL3108878) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a |
University of Cambridge Curated by ChEMBL | Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis | ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50446137![]() (CHEMBL3108880) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.60E+4 | n/a | n/a | n/a | n/a | n/a |
University of Cambridge Curated by ChEMBL | Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis | ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50446138![]() (CHEMBL3108881) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a |
University of Cambridge Curated by ChEMBL | Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis | ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50446139![]() (CHEMBL3108882 | US10730870, Example 135 | US115120...) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a |
University of Cambridge Curated by ChEMBL | Assay Description Displacement of 19-mer HIF-1alpha peptide from VHL (unknown origin) by isothermal titration calorimetry analysis | ACS Med Chem Lett 5: 23-28 (2014) Article DOI: 10.1021/ml400296c BindingDB Entry DOI: 10.7270/Q2NK3GH1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Elongin-C (Homo sapiens (Human)) | BDBM50463158![]() (CHEMBL4244103) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6 tagged VHL (54 to 213 residues)/ELoC (17 to 112 residues)/EloB (1 to 120 residues) (unknown origin) complex expre... | J Med Chem 61: 7387-7393 (2018) Article DOI: 10.1021/acs.jmedchem.8b00842 BindingDB Entry DOI: 10.7270/Q2639SCC | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
von Hippel-Lindau disease tumor suppressor (Homo sapiens (Human)) | BDBM50099053![]() (CHEMBL3344149) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | CHEMBL KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 2.04E+3 | n/a | n/a | n/a | n/a | n/a |
University of Dundee Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-tagged pVHL (54 to 213 amino acids) (unknown origin) expressed in Escherichia coli BL21 (DE3) by isothermal titra... | J Med Chem 57: 8657-63 (2014) Article DOI: 10.1021/jm5011258 BindingDB Entry DOI: 10.7270/Q2HD7XDM | |||||||||||
More data for this Ligand-Target Pair |