Compile Data Set for Download or QSAR

Found 19 hits with Last Name = 'amano' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NACHT, LRR and PYD domains-containing protein 3 (Mus musculus)	BDBM50276373 (CHEMBL4125713) Show SMILES [H][C@@]12CO[C@@]([H])(O1)C(=O)C(F)=C2 |r,c:11| Show InChI InChI=1S/C6H5FO3/c7-4-1-3-2-9-6(10-3)5(4)8/h1,3,6H,2H2/t3-,6+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Mus musculus)	BDBM50276377 (CHEMBL4129636) Show SMILES [H][C@@]12CO[C@@]([H])(O1)C(OC(C)=O)=C(F)C2C(C)=O |r,t:12| Show InChI InChI=1S/C10H11FO5/c1-4(12)7-6-3-14-10(16-6)9(8(7)11)15-5(2)13/h6-7,10H,3H2,1-2H3/t6-,7?,10-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Mus musculus)	BDBM50276378 (CHEMBL4126941) Show SMILES [H][C@]12CO[C@]([H])(O1)C(=O)C=C2 |r,c:10| Show InChI InChI=1S/C6H6O3/c7-5-2-1-4-3-8-6(5)9-4/h1-2,4,6H,3H2/t4-,6+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Mus musculus)	BDBM50276376 (CHEMBL4126909) Show SMILES CC(=O)OC[C@H]1OCC(=O)C(F)=C1 |r,c:11| Show InChI InChI=1S/C8H9FO4/c1-5(10)12-3-6-2-7(9)8(11)4-13-6/h2,6H,3-4H2,1H3/t6-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Homo sapiens (Human))	BDBM50276381 (CHEMBL4128029) Show SMILES CCCC(=O)OC[C@H]1OCC(=O)C=C1 |r,c:12| Show InChI InChI=1S/C10H14O4/c1-2-3-10(12)14-7-9-5-4-8(11)6-13-9/h4-5,9H,2-3,6-7H2,1H3/t9-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Mus musculus)	BDBM50276381 (CHEMBL4128029) Show SMILES CCCC(=O)OC[C@H]1OCC(=O)C=C1 |r,c:12| Show InChI InChI=1S/C10H14O4/c1-2-3-10(12)14-7-9-5-4-8(11)6-13-9/h4-5,9H,2-3,6-7H2,1H3/t9-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Homo sapiens (Human))	BDBM50276376 (CHEMBL4126909) Show SMILES CC(=O)OC[C@H]1OCC(=O)C(F)=C1 |r,c:11| Show InChI InChI=1S/C8H9FO4/c1-5(10)12-3-6-2-7(9)8(11)4-13-6/h2,6H,3-4H2,1H3/t6-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Homo sapiens (Human))	BDBM50276377 (CHEMBL4129636) Show SMILES [H][C@@]12CO[C@@]([H])(O1)C(OC(C)=O)=C(F)C2C(C)=O |r,t:12| Show InChI InChI=1S/C10H11FO5/c1-4(12)7-6-3-14-10(16-6)9(8(7)11)15-5(2)13/h6-7,10H,3H2,1-2H3/t6-,7?,10-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Homo sapiens (Human))	BDBM50276372 (CHEMBL4128176) Show SMILES CC(=O)OC[C@H]1OCC(=O)C=C1 |r,c:10| Show InChI InChI=1S/C8H10O4/c1-6(9)11-5-8-3-2-7(10)4-12-8/h2-3,8H,4-5H2,1H3/t8-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Homo sapiens (Human))	BDBM50276373 (CHEMBL4125713) Show SMILES [H][C@@]12CO[C@@]([H])(O1)C(=O)C(F)=C2 |r,c:11| Show InChI InChI=1S/C6H5FO3/c7-4-1-3-2-9-6(10-3)5(4)8/h1,3,6H,2H2/t3-,6+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Homo sapiens (Human))	BDBM50276375 (CHEMBL4129407) Show SMILES CCCCCCCC(=O)OC[C@H]1OCC(=O)C=C1 |r,c:16| Show InChI InChI=1S/C14H22O4/c1-2-3-4-5-6-7-14(16)18-11-13-9-8-12(15)10-17-13/h8-9,13H,2-7,10-11H2,1H3/t13-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Mus musculus)	BDBM50276372 (CHEMBL4128176) Show SMILES CC(=O)OC[C@H]1OCC(=O)C=C1 |r,c:10| Show InChI InChI=1S/C8H10O4/c1-6(9)11-5-8-3-2-7(10)4-12-8/h2-3,8H,4-5H2,1H3/t8-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Homo sapiens (Human))	BDBM50276378 (CHEMBL4126941) Show SMILES [H][C@]12CO[C@]([H])(O1)C(=O)C=C2 |r,c:10| Show InChI InChI=1S/C6H6O3/c7-5-2-1-4-3-8-6(5)9-4/h1-2,4,6H,3H2/t4-,6+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Mus musculus)	BDBM50276375 (CHEMBL4129407) Show SMILES CCCCCCCC(=O)OC[C@H]1OCC(=O)C=C1 |r,c:16| Show InChI InChI=1S/C14H22O4/c1-2-3-4-5-6-7-14(16)18-11-13-9-8-12(15)10-17-13/h8-9,13H,2-7,10-11H2,1H3/t13-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Mus musculus)	BDBM50276380 (CHEMBL4127699) Show SMILES OC[C@H]1OCC(=O)C=C1 |r,c:7| Show InChI InChI=1S/C6H8O3/c7-3-6-2-1-5(8)4-9-6/h1-2,6-7H,3-4H2/t6-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Homo sapiens (Human))	BDBM50276380 (CHEMBL4127699) Show SMILES OC[C@H]1OCC(=O)C=C1 |r,c:7| Show InChI InChI=1S/C6H8O3/c7-3-6-2-1-5(8)4-9-6/h1-2,6-7H,3-4H2/t6-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Mus musculus)	BDBM50276374 (CHEMBL4126946) Show SMILES OC[C@H]1OCC(=O)C[C@@H]1O |r| Show InChI InChI=1S/C6H10O4/c7-2-6-5(9)1-4(8)3-10-6/h5-7,9H,1-3H2/t5-,6+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+6	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Homo sapiens (Human))	BDBM50276374 (CHEMBL4126946) Show SMILES OC[C@H]1OCC(=O)C[C@@H]1O |r| Show InChI InChI=1S/C6H10O4/c7-2-6-5(9)1-4(8)3-10-6/h5-7,9H,1-3H2/t5-,6+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+6	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Mus musculus)	BDBM50276379 (CHEBI:16715 | CHEMBL1234723) Show SMILES OC[C@H]1OCC(=O)[C@@H](O)[C@@H]1O |r| Show InChI InChI=1S/C6H10O5/c7-1-4-6(10)5(9)3(8)2-11-4/h4-7,9-10H,1-2H2/t4-,5-,6-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.90E+7	n/a	n/a	n/a	n/a	n/a	n/a
The Noguchi Institute Curated by ChEMBL					Assay Description Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...				Bioorg Med Chem 26: 3763-3772 (2018) Article DOI: 10.1016/j.bmc.2017.11.041 BindingDB Entry DOI: 10.7270/Q25H7JSX
					More data for this Ligand-Target Pair