Found 23 hits with Last Name = 'connarn' and Initial = 'j' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Serine/threonine-protein phosphatase 5
(Homo sapiens (Human)) | BDBM217369
(MEEVD)Show SMILES CSCC[C@H](N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C24H39N5O12S/c1-11(2)19(23(39)28-15(24(40)41)10-18(34)35)29-22(38)14(5-7-17(32)33)27-21(37)13(4-6-16(30)31)26-20(36)12(25)8-9-42-3/h11-15,19H,4-10,25H2,1-3H3,(H,26,36)(H,27,37)(H,28,39)(H,29,38)(H,30,31)(H,32,33)(H,34,35)(H,40,41)/t12-,13-,14-,15-,19-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 140 | n/a | n/a | n/a | 7.4 | 25 |
University of Michigan
| Assay Description
All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl... |
J Biol Chem 289: 2908-17 (2014)
Article DOI: 10.1074/jbc.M113.519421
BindingDB Entry DOI: 10.7270/Q2GH9GSN |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443579
(CHEMBL3091725)Show SMILES CCn1c(=O)c(sc1=Cc1scc[n+]1Cc1ccc(CNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)cc1)=C1Sc2cccc(F)c2N1C |r,w:38.43,8.9| Show InChI InChI=1S/C35H37FN6O3S4/c1-3-42-29(49-32(33(42)44)34-40(2)31-23(36)7-6-9-26(31)48-34)17-28-41(15-16-46-28)19-22-13-11-21(12-14-22)18-37-27(43)10-5-4-8-25-30-24(20-47-25)38-35(45)39-30/h6-7,9,11-17,24-25,30H,3-5,8,10,18-20H2,1-2H3,(H2-,37,38,39,43,45)/p+1/t24-,25-,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein phosphatase 5
(Homo sapiens (Human)) | BDBM217373
(SSGPTIEEVD)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C42H68N10O20/c1-6-19(4)32(50-41(70)33(20(5)55)51-38(67)26-8-7-13-52(26)27(56)15-44-35(64)25(17-54)48-34(63)21(43)16-53)40(69)46-22(9-11-28(57)58)36(65)45-23(10-12-29(59)60)37(66)49-31(18(2)3)39(68)47-24(42(71)72)14-30(61)62/h18-26,31-33,53-55H,6-17,43H2,1-5H3,(H,44,64)(H,45,65)(H,46,69)(H,47,68)(H,48,63)(H,49,66)(H,50,70)(H,51,67)(H,57,58)(H,59,60)(H,61,62)(H,71,72)/t19-,20+,21-,22-,23-,24-,25-,26-,31-,32-,33-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | 7.4 | 25 |
University of Michigan
| Assay Description
All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl... |
J Biol Chem 289: 2908-17 (2014)
Article DOI: 10.1074/jbc.M113.519421
BindingDB Entry DOI: 10.7270/Q2GH9GSN |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein phosphatase 5
(Homo sapiens (Human)) | BDBM217374
(GSGPTIEEVD)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C41H66N10O19/c1-6-19(4)32(49-40(68)33(20(5)53)50-37(65)25-8-7-13-51(25)27(55)16-43-34(62)24(17-52)44-26(54)15-42)39(67)46-21(9-11-28(56)57)35(63)45-22(10-12-29(58)59)36(64)48-31(18(2)3)38(66)47-23(41(69)70)14-30(60)61/h18-25,31-33,52-53H,6-17,42H2,1-5H3,(H,43,62)(H,44,54)(H,45,63)(H,46,67)(H,47,66)(H,48,64)(H,49,68)(H,50,65)(H,56,57)(H,58,59)(H,60,61)(H,69,70)/t19-,20+,21-,22-,23-,24-,25-,31-,32-,33-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 1.55E+3 | n/a | n/a | n/a | 7.4 | 25 |
University of Michigan
| Assay Description
All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl... |
J Biol Chem 289: 2908-17 (2014)
Article DOI: 10.1074/jbc.M113.519421
BindingDB Entry DOI: 10.7270/Q2GH9GSN |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein phosphatase 5
(Homo sapiens (Human)) | BDBM217371
(DDTSRMEEVD)Show SMILES CSCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(O)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C45H73N13O23S/c1-18(2)33(42(78)55-26(44(80)81)16-32(69)70)57-39(75)23(8-10-29(63)64)52-37(73)22(7-9-28(61)62)51-38(74)24(11-13-82-4)53-36(72)21(6-5-12-49-45(47)48)50-41(77)27(17-59)56-43(79)34(19(3)60)58-40(76)25(15-31(67)68)54-35(71)20(46)14-30(65)66/h18-27,33-34,59-60H,5-17,46H2,1-4H3,(H,50,77)(H,51,74)(H,52,73)(H,53,72)(H,54,71)(H,55,78)(H,56,79)(H,57,75)(H,58,76)(H,61,62)(H,63,64)(H,65,66)(H,67,68)(H,69,70)(H,80,81)(H4,47,48,49)/t19-,20+,21+,22+,23+,24+,25+,26+,27+,33+,34+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 79 | n/a | n/a | n/a | 7.4 | 25 |
University of Michigan
| Assay Description
All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl... |
J Biol Chem 289: 2908-17 (2014)
Article DOI: 10.1074/jbc.M113.519421
BindingDB Entry DOI: 10.7270/Q2GH9GSN |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein phosphatase 5
(Homo sapiens (Human)) | BDBM217372
(EDASRMEEVD)Show SMILES CSCC[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C45H73N13O22S/c1-19(2)34(43(78)56-27(44(79)80)17-33(68)69)58-40(75)24(9-12-31(64)65)53-38(73)23(8-11-30(62)63)52-39(74)25(13-15-81-4)54-37(72)22(6-5-14-49-45(47)48)51-42(77)28(18-59)57-35(70)20(3)50-41(76)26(16-32(66)67)55-36(71)21(46)7-10-29(60)61/h19-28,34,59H,5-18,46H2,1-4H3,(H,50,76)(H,51,77)(H,52,74)(H,53,73)(H,54,72)(H,55,71)(H,56,78)(H,57,70)(H,58,75)(H,60,61)(H,62,63)(H,64,65)(H,66,67)(H,68,69)(H,79,80)(H4,47,48,49)/t20-,21-,22-,23-,24-,25-,26-,27-,28-,34-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 77 | n/a | n/a | n/a | 7.4 | 25 |
University of Michigan
| Assay Description
All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl... |
J Biol Chem 289: 2908-17 (2014)
Article DOI: 10.1074/jbc.M113.519421
BindingDB Entry DOI: 10.7270/Q2GH9GSN |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein phosphatase 5
(Homo sapiens (Human)) | BDBM217375
(DVEEM)Show SMILES CSCC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(O)=O |r| Show InChI InChI=1S/C24H39N5O12S/c1-11(2)19(29-20(36)12(25)10-18(34)35)23(39)27-14(5-7-17(32)33)21(37)26-13(4-6-16(30)31)22(38)28-15(24(40)41)8-9-42-3/h11-15,19H,4-10,25H2,1-3H3,(H,26,37)(H,27,39)(H,28,38)(H,29,36)(H,30,31)(H,32,33)(H,34,35)(H,40,41)/t12-,13-,14-,15-,19-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | 7.4 | 25 |
University of Michigan
| Assay Description
All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl... |
J Biol Chem 289: 2908-17 (2014)
Article DOI: 10.1074/jbc.M113.519421
BindingDB Entry DOI: 10.7270/Q2GH9GSN |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein phosphatase 5
(Homo sapiens (Human)) | BDBM217377
(GSGPTMEEVD)Show SMILES CSCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CO)NC(=O)CN)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C40H64N10O19S/c1-18(2)31(38(66)47-23(40(68)69)14-30(59)60)48-36(64)21(8-10-29(57)58)45-34(62)20(7-9-28(55)56)44-35(63)22(11-13-70-4)46-39(67)32(19(3)52)49-37(65)25-6-5-12-50(25)27(54)16-42-33(61)24(17-51)43-26(53)15-41/h18-25,31-32,51-52H,5-17,41H2,1-4H3,(H,42,61)(H,43,53)(H,44,63)(H,45,62)(H,46,67)(H,47,66)(H,48,64)(H,49,65)(H,55,56)(H,57,58)(H,59,60)(H,68,69)/t19-,20+,21+,22+,23+,24+,25+,31+,32+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 133 | n/a | n/a | n/a | 7.4 | 25 |
University of Michigan
| Assay Description
All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl... |
J Biol Chem 289: 2908-17 (2014)
Article DOI: 10.1074/jbc.M113.519421
BindingDB Entry DOI: 10.7270/Q2GH9GSN |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein phosphatase 5
(Homo sapiens (Human)) | BDBM217376
(DDTSRIEEVD)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](N)CC(O)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C46H75N13O23/c1-6-19(4)34(43(79)53-23(9-11-28(62)63)37(73)52-24(10-12-29(64)65)39(75)57-33(18(2)3)42(78)55-26(45(81)82)16-32(70)71)58-38(74)22(8-7-13-50-46(48)49)51-41(77)27(17-60)56-44(80)35(20(5)61)59-40(76)25(15-31(68)69)54-36(72)21(47)14-30(66)67/h18-27,33-35,60-61H,6-17,47H2,1-5H3,(H,51,77)(H,52,73)(H,53,79)(H,54,72)(H,55,78)(H,56,80)(H,57,75)(H,58,74)(H,59,76)(H,62,63)(H,64,65)(H,66,67)(H,68,69)(H,70,71)(H,81,82)(H4,48,49,50)/t19-,20+,21-,22-,23-,24-,25-,26-,27-,33-,34-,35-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 420 | n/a | n/a | n/a | 7.4 | 25 |
University of Michigan
| Assay Description
All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl... |
J Biol Chem 289: 2908-17 (2014)
Article DOI: 10.1074/jbc.M113.519421
BindingDB Entry DOI: 10.7270/Q2GH9GSN |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443566
(CHEMBL3091931)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2cc(ccc2N1C)C(F)(F)F |r,w:37.41,8.9| Show InChI InChI=1S/C36H43F3N6O3S3/c1-3-45-30(51-32(33(45)47)34-43(2)26-16-15-23(36(37,38)39)20-28(26)50-34)21-24-12-8-11-19-44(24)18-10-5-4-9-17-40-29(46)14-7-6-13-27-31-25(22-49-27)41-35(48)42-31/h8,11-12,15-16,19-21,25,27,31H,3-7,9-10,13-14,17-18,22H2,1-2H3,(H2-,40,41,42,46,48)/p+1/t25-,27-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443567
(CHEMBL3091930)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2cc(OC)ccc2N1C |r,w:37.41,8.9| Show InChI InChI=1S/C36H46N6O4S3/c1-4-42-31(49-33(34(42)44)35-40(2)27-17-16-25(46-3)22-29(27)48-35)21-24-13-9-12-20-41(24)19-11-6-5-10-18-37-30(43)15-8-7-14-28-32-26(23-47-28)38-36(45)39-32/h9,12-13,16-17,20-22,26,28,32H,4-8,10-11,14-15,18-19,23H2,1-3H3,(H2-,37,38,39,43,45)/p+1/t26-,28-,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443568
(CHEMBL3091929)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2ccc(cc2N1C)C(C)(F)F |r,w:37.41,8.9| Show InChI InChI=1S/C37H46F2N6O3S3/c1-4-45-31(51-33(34(45)47)35-43(3)27-21-24(37(2,38)39)16-17-28(27)50-35)22-25-13-9-12-20-44(25)19-11-6-5-10-18-40-30(46)15-8-7-14-29-32-26(23-49-29)41-36(48)42-32/h9,12-13,16-17,20-22,26,29,32H,4-8,10-11,14-15,18-19,23H2,1-3H3,(H2-,40,41,42,46,48)/p+1/t26-,29-,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443569
(CHEMBL3091928)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2ccc(OC)cc2N1C |r,w:37.41,8.9| Show InChI InChI=1S/C36H46N6O4S3/c1-4-42-31(49-33(34(42)44)35-40(2)27-22-25(46-3)16-17-28(27)48-35)21-24-13-9-12-20-41(24)19-11-6-5-10-18-37-30(43)15-8-7-14-29-32-26(23-47-29)38-36(45)39-32/h9,12-13,16-17,20-22,26,29,32H,4-8,10-11,14-15,18-19,23H2,1-3H3,(H2-,37,38,39,43,45)/p+1/t26-,29-,32-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443570
(CHEMBL3091927)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2c(cccc2Cl)N1C |r,w:37.41,8.9| Show InChI InChI=1S/C35H43ClN6O3S3/c1-3-42-29(47-32(33(42)44)34-40(2)26-15-12-14-24(36)31(26)48-34)21-23-13-8-11-20-41(23)19-10-5-4-9-18-37-28(43)17-7-6-16-27-30-25(22-46-27)38-35(45)39-30/h8,11-15,20-21,25,27,30H,3-7,9-10,16-19,22H2,1-2H3,(H2-,37,38,39,43,45)/p+1/t25-,27-,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443571
(CHEMBL3091926)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2cc(Cl)ccc2N1C |r,w:37.41,8.9| Show InChI InChI=1S/C35H43ClN6O3S3/c1-3-42-30(48-32(33(42)44)34-40(2)26-16-15-23(36)20-28(26)47-34)21-24-12-8-11-19-41(24)18-10-5-4-9-17-37-29(43)14-7-6-13-27-31-25(22-46-27)38-35(45)39-31/h8,11-12,15-16,19-21,25,27,31H,3-7,9-10,13-14,17-18,22H2,1-2H3,(H2-,37,38,39,43,45)/p+1/t25-,27-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443572
(CHEMBL3091728)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2ccc(Cl)cc2N1C |r,w:37.41,8.9| Show InChI InChI=1S/C35H43ClN6O3S3/c1-3-42-30(48-32(33(42)44)34-40(2)26-20-23(36)15-16-27(26)47-34)21-24-12-8-11-19-41(24)18-10-5-4-9-17-37-29(43)14-7-6-13-28-31-25(22-46-28)38-35(45)39-31/h8,11-12,15-16,19-21,25,28,31H,3-7,9-10,13-14,17-18,22H2,1-2H3,(H2-,37,38,39,43,45)/p+1/t25-,28-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443573
(CHEMBL3091727)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2cccc(Cl)c2N1C |r,w:37.41,8.9| Show InChI InChI=1S/C35H43ClN6O3S3/c1-3-42-29(48-32(33(42)44)34-40(2)31-24(36)14-12-16-27(31)47-34)21-23-13-8-11-20-41(23)19-10-5-4-9-18-37-28(43)17-7-6-15-26-30-25(22-46-26)38-35(45)39-30/h8,11-14,16,20-21,25-26,30H,3-7,9-10,15,17-19,22H2,1-2H3,(H2-,37,38,39,43,45)/p+1/t25-,26-,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443574
(CHEMBL3091726)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2c(cccc2F)N1C |r,w:37.41,8.9| Show InChI InChI=1S/C35H43FN6O3S3/c1-3-42-29(47-32(33(42)44)34-40(2)26-15-12-14-24(36)31(26)48-34)21-23-13-8-11-20-41(23)19-10-5-4-9-18-37-28(43)17-7-6-16-27-30-25(22-46-27)38-35(45)39-30/h8,11-15,20-21,25,27,30H,3-7,9-10,16-19,22H2,1-2H3,(H2-,37,38,39,43,45)/p+1/t25-,27-,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443575
(CHEMBL3091944)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2cc(F)ccc2N1C |r,w:37.41,8.9| Show InChI InChI=1S/C35H43FN6O3S3/c1-3-42-30(48-32(33(42)44)34-40(2)26-16-15-23(36)20-28(26)47-34)21-24-12-8-11-19-41(24)18-10-5-4-9-17-37-29(43)14-7-6-13-27-31-25(22-46-27)38-35(45)39-31/h8,11-12,15-16,19-21,25,27,31H,3-7,9-10,13-14,17-18,22H2,1-2H3,(H2-,37,38,39,43,45)/p+1/t25-,27-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443576
(CHEMBL3091943)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2ccc(F)cc2N1C |r,w:37.41,8.9| Show InChI InChI=1S/C35H43FN6O3S3/c1-3-42-30(48-32(33(42)44)34-40(2)26-20-23(36)15-16-27(26)47-34)21-24-12-8-11-19-41(24)18-10-5-4-9-17-37-29(43)14-7-6-13-28-31-25(22-46-28)38-35(45)39-31/h8,11-12,15-16,19-21,25,28,31H,3-7,9-10,13-14,17-18,22H2,1-2H3,(H2-,37,38,39,43,45)/p+1/t25-,28-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443577
(CHEMBL3091942)Show SMILES CCn1c(=O)c(sc1=Cc1cccc[n+]1CCCCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)=C1Sc2cccc(F)c2N1C |r,w:37.41,8.9| Show InChI InChI=1S/C35H43FN6O3S3/c1-3-42-29(48-32(33(42)44)34-40(2)31-24(36)14-12-16-27(31)47-34)21-23-13-8-11-20-41(23)19-10-5-4-9-18-37-28(43)17-7-6-15-26-30-25(22-46-26)38-35(45)39-30/h8,11-14,16,20-21,25-26,30H,3-7,9-10,15,17-19,22H2,1-2H3,(H2-,37,38,39,43,45)/p+1/t25-,26-,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.09E+4 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Heat shock cognate 71 kDa protein
(Homo sapiens (Human)) | BDBM50443578
(CHEMBL3091941)Show SMILES CCn1c(=Cc2cccc[n+]2CCCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)sc(=C2Sc3ccccc3N2C)c1=O |r,w:35.38,4.4| Show InChI InChI=1S/C35H44N6O3S3/c1-3-41-30(47-32(33(41)43)34-39(2)26-15-6-7-16-27(26)46-34)22-24-14-10-13-21-40(24)20-12-5-4-11-19-36-29(42)18-9-8-17-28-31-25(23-45-28)37-35(44)38-31/h6-7,10,13-16,21-22,25,28,31H,3-5,8-9,11-12,17-20,23H2,1-2H3,(H2-,36,37,38,42,44)/p+1/t25-,28-,31-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of California at San Francisco
Curated by ChEMBL
| Assay Description
Binding affinity to human HSC70 after 3 hrs by ELISA |
ACS Med Chem Lett 4: (2013)
Article DOI: 10.1021/ml400204n
BindingDB Entry DOI: 10.7270/Q2Q81FHC |
More data for this
Ligand-Target Pair | |
Serine/threonine-protein phosphatase 5
(Homo sapiens (Human)) | BDBM217370
(IEEVD)Show SMILES CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C25H41N5O12/c1-5-12(4)19(26)23(39)28-13(6-8-16(31)32)21(37)27-14(7-9-17(33)34)22(38)30-20(11(2)3)24(40)29-15(25(41)42)10-18(35)36/h11-15,19-20H,5-10,26H2,1-4H3,(H,27,37)(H,28,39)(H,29,40)(H,30,38)(H,31,32)(H,33,34)(H,35,36)(H,41,42)/t12-,13-,14-,15-,19-,20-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 426 | n/a | n/a | n/a | 7.4 | 25 |
University of Michigan
| Assay Description
All fluorescence polarization experiments were conducted in 384-well, black, low volume, round-bottomed plates (Corning) using a BioTeck Synergy 2 pl... |
J Biol Chem 289: 2908-17 (2014)
Article DOI: 10.1074/jbc.M113.519421
BindingDB Entry DOI: 10.7270/Q2GH9GSN |
More data for this
Ligand-Target Pair | |
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