Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50250655 (CHEMBL4059985 | US10961200, Compound 189 | US11247...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250655 (CHEMBL4059985 | US10961200, Compound 189 | US11247...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250655 (CHEMBL4059985 | US10961200, Compound 189 | US11247...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Binding affinity to human His-tagged LDHA in presence of NADH by SPR assay | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM197160 (GNE-140 (6)) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | <10 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human LDHA using sodium pyruvate as substrate in presence of NAPDH | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445521 (CHEMBL3103033 | US11345702, Table 1.21 | US2023039...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250653 (CHEMBL4090677 | US10961200, Compound 46 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM30884 (1-(3-methylphenyl)-5-(piperidin-1-ylcarbonyl)-1H-b...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250653 (CHEMBL4090677 | US10961200, Compound 46 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Binding affinity to human His-tagged LDHA in presence of NADH by SPR assay | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445520 (CHEMBL3103034) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445516 (CHEMBL3103038) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445514 (CHEMBL3103040 | US11345702, Table 1.33 | US2023039...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50250653 (CHEMBL4090677 | US10961200, Compound 46 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50250677 (CHEMBL4100845 | US10961200, Compound 52 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445537 (CHEMBL3103018) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445523 (CHEMBL3103032) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445515 (CHEMBL3103039) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445562 (CHEMBL3102994) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50250656 (CHEMBL4081890 | US11247971, Cmpd ID 276) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445522 (CHEMBL3102860) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250677 (CHEMBL4100845 | US10961200, Compound 52 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250677 (CHEMBL4100845 | US10961200, Compound 52 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250656 (CHEMBL4081890 | US11247971, Cmpd ID 276) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250656 (CHEMBL4081890 | US11247971, Cmpd ID 276) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445511 (CHEMBL3103043) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445555 (CHEMBL3103000) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445561 (CHEMBL3102995) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50103568 (CHEMBL3335794) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250648 (CHEMBL4080497 | US10961200, Compound 20 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445549 (CHEMBL3103006) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445560 (CHEMBL3102996) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50103568 (CHEMBL3335794) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250648 (CHEMBL4080497 | US10961200, Compound 20 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250689 (CHEMBL4069726 | US10961200, Compound 47 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Binding affinity to human His-tagged LDHA in presence of NADH by SPR assay | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445519 (CHEMBL3103035) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445557 (CHEMBL3102998) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445559 (CHEMBL3102997) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445535 (CHEMBL3103020) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50250648 (CHEMBL4080497 | US10961200, Compound 20 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50347949 (CHEMBL599406 | US8637558, 46) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of PGDH (unknown origin) | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250652 (CHEMBL4101800 | US10961200, Compound 42 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250652 (CHEMBL4101800 | US10961200, Compound 42 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Binding affinity to human His-tagged LDHA in presence of NADH by SPR assay | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445563 (CHEMBL1408258) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human)) | BDBM50445512 (CHEMBL3103042) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human HPGD using PGE2 as substrate after 15 mins by fluorescence assay | Bioorg Med Chem Lett 24: 630-5 (2014) Article DOI: 10.1016/j.bmcl.2013.11.081 BindingDB Entry DOI: 10.7270/Q28G8N6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250649 (CHEMBL4076027 | US10961200, Compound 51 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Binding affinity to human His-tagged LDHA in presence of NADH by SPR assay | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250649 (CHEMBL4076027 | US10961200, Compound 51 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250649 (CHEMBL4076027 | US10961200, Compound 51 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and EDTA by diaphorase/resazurin based fluorescen... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase B chain (Homo sapiens (Human)) | BDBM50250652 (CHEMBL4101800 | US10961200, Compound 42 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250667 (CHEMBL4075666 | US10961200, Compound 40 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Binding affinity to human His-tagged LDHA in presence of NADH by SPR assay | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250667 (CHEMBL4075666 | US10961200, Compound 40 | US112479...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Inhibition of human liver LDHA using sodium pyruvate as substrate after 5 mins in presence of NAPDH and in absence of EDTA by diaphorase/resazurin ba... | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
L-lactate dehydrogenase A chain (Homo sapiens (Human)) | BDBM50250691 (CHEMBL4062709 | US10961200, Compound 166 | US11247...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
National Center for Advancing Translational Sciences Curated by ChEMBL | Assay Description Binding affinity to human His-tagged LDHA in presence of NADH by SPR assay | J Med Chem 60: 9184-9204 (2017) Article DOI: 10.1021/acs.jmedchem.7b00941 BindingDB Entry DOI: 10.7270/Q2DJ5J28 | |||||||||||
More data for this Ligand-Target Pair |
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