Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50480766![]() (2''-Deoxycytidine 5''-Triphosphate | CHEBI:16311 |...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.14E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to wild type HIV1 LAI reverse transcriptase | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50138406![]() (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50480766![]() (2''-Deoxycytidine 5''-Triphosphate | CHEBI:16311 |...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.99E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50370476![]() (Combivir | ZIDOVUDINE TRIPHOSPHATE) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.99E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to wild type HIV1 LAI reverse transcriptase | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50164648![]() (2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 2.08E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to wild type HIV1 LAI reverse transcriptase | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50138406![]() (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.20E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M184V mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50370476![]() (Combivir | ZIDOVUDINE TRIPHOSPHATE) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50370476![]() (Combivir | ZIDOVUDINE TRIPHOSPHATE) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50478975![]() (AZIDOTHYMIDINE MONOPHOSPHATE | Zidovudine Monophos...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M184V mutant assessed as ATP-mediated excision of zidovudine-monophosphate terminated DNA/DNA temp... | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50478975![]() (AZIDOTHYMIDINE MONOPHOSPHATE | Zidovudine Monophos...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant assessed as ATP-mediated excision of zidovudine-monophosphate terminated D... | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50478975![]() (AZIDOTHYMIDINE MONOPHOSPHATE | Zidovudine Monophos...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant assessed as ATP-mediated excision of zidovudine-monophosphate termin... | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50478975![]() (AZIDOTHYMIDINE MONOPHOSPHATE | Zidovudine Monophos...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/K65R mutant assessed as ATP-mediated excision of zidovudine-monophosphate termina... | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50138406![]() (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to wild type HIV1 LAI reverse transcriptase | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50138406![]() (3TC Triphosphate | CHEMBL1230 | LAMIVUDINE | Lamiv...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 9.80E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50480766![]() (2''-Deoxycytidine 5''-Triphosphate | CHEBI:16311 |...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.49E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M184V mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50370476![]() (Combivir | ZIDOVUDINE TRIPHOSPHATE) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M184V mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50164648![]() (2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50164648![]() (2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 2.65E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y/M184V mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase (Human immunodeficiency virus 1) | BDBM50478975![]() (AZIDOTHYMIDINE MONOPHOSPHATE | Zidovudine Monophos...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to wild type HIV1 LAI reverse transcriptase assessed as ATP-mediated excision of zidovudine-monophosphate terminated DNA/DNA templat... | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50164648![]() (2'-deoxythymidine triphosphate | 5'-TTP | CHEMBL36...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 2.85E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M184V mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase protein (Human immunodeficiency virus 1) | BDBM50480766![]() (2''-Deoxycytidine 5''-Triphosphate | CHEBI:16311 |...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh School of Medicine Curated by ChEMBL | Assay Description Binding affinity to HIV1 LAI reverse transcriptase M41L/L210W/T215Y mutant | Antimicrob Agents Chemother 52: 157-63 (2008) Article DOI: 10.1128/aac.00904-07 BindingDB Entry DOI: 10.7270/Q2CV4MK7 | |||||||||||
More data for this Ligand-Target Pair |