Compile Data Set for Download or QSAR

Found 167 hits with Last Name = 'gambino' and Initial = 'jj'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160350 (Acetic acid (R)-5-[2-(3,4-dichloro-benzylamino)-6-...) Show SMILES C[C@H](CCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12)OC(C)=O Show InChI InChI=1S/C20H23Cl2N5O3/c1-12(30-13(2)28)5-3-4-8-27-11-24-18-17(27)19(29)26-20(25-18)23-10-14-6-7-15(21)16(22)9-14/h6-7,9,11-12H,3-5,8,10H2,1-2H3,(H2,23,25,26,29)/t12-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160340 (2-(3,4-Dichloro-benzylamino)-7-((R)-5-hydroxy-hexy...) Show SMILES C[C@@H](O)CCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H21Cl2N5O2/c1-11(26)4-2-3-7-25-10-22-16-15(25)17(27)24-18(23-16)21-9-12-5-6-13(19)14(20)8-12/h5-6,8,10-11,26H,2-4,7,9H2,1H3,(H2,21,23,24,27)/t11-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160338 (4-[2-(3,4-Dichloro-benzylamino)-6-oxo-1,6-dihydro-...) Show SMILES CCOC(=O)CCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H19Cl2N5O3/c1-2-28-14(26)4-3-7-25-10-22-16-15(25)17(27)24-18(23-16)21-9-11-5-6-12(19)13(20)8-11/h5-6,8,10H,2-4,7,9H2,1H3,(H2,21,23,24,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160342 (2-(3,4-Dichloro-benzylamino)-7-(4-morpholin-4-yl-b...) Show SMILES Clc1ccc(CNc2nc3ncn(CCCCN4CCOCC4)c3c(=O)[nH]2)cc1Cl Show InChI InChI=1S/C20H24Cl2N6O2/c21-15-4-3-14(11-16(15)22)12-23-20-25-18-17(19(29)26-20)28(13-24-18)6-2-1-5-27-7-9-30-10-8-27/h3-4,11,13H,1-2,5-10,12H2,(H2,23,25,26,29)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160342 (2-(3,4-Dichloro-benzylamino)-7-(4-morpholin-4-yl-b...) Show SMILES Clc1ccc(CNc2nc3ncn(CCCCN4CCOCC4)c3c(=O)[nH]2)cc1Cl Show InChI InChI=1S/C20H24Cl2N6O2/c21-15-4-3-14(11-16(15)22)12-23-20-25-18-17(19(29)26-20)28(13-24-18)6-2-1-5-27-7-9-30-10-8-27/h3-4,11,13H,1-2,5-10,12H2,(H2,23,25,26,29)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160340 (2-(3,4-Dichloro-benzylamino)-7-((R)-5-hydroxy-hexy...) Show SMILES C[C@@H](O)CCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H21Cl2N5O2/c1-11(26)4-2-3-7-25-10-22-16-15(25)17(27)24-18(23-16)21-9-12-5-6-13(19)14(20)8-12/h5-6,8,10-11,26H,2-4,7,9H2,1H3,(H2,21,23,24,27)/t11-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160345 (2-(3,4-Dichloro-benzylamino)-7-(5-hydroxy-pentyl)-...) Show SMILES OCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C17H19Cl2N5O2/c18-12-5-4-11(8-13(12)19)9-20-17-22-15-14(16(26)23-17)24(10-21-15)6-2-1-3-7-25/h4-5,8,10,25H,1-3,6-7,9H2,(H2,20,22,23,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160344 (Acetic acid 5-[2-(3,4-dichloro-benzylamino)-6-oxo-...) Show SMILES CC(=O)OCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C19H21Cl2N5O3/c1-12(27)29-8-4-2-3-7-26-11-23-17-16(26)18(28)25-19(24-17)22-10-13-5-6-14(20)15(21)9-13/h5-6,9,11H,2-4,7-8,10H2,1H3,(H2,22,24,25,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160344 (Acetic acid 5-[2-(3,4-dichloro-benzylamino)-6-oxo-...) Show SMILES CC(=O)OCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C19H21Cl2N5O3/c1-12(27)29-8-4-2-3-7-26-11-23-17-16(26)18(28)25-19(24-17)22-10-13-5-6-14(20)15(21)9-13/h5-6,9,11H,2-4,7-8,10H2,1H3,(H2,22,24,25,28)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160351 (2-(3,4-Dichloro-benzylamino)-7-(4-hydroxy-butyl)-1...) Show SMILES OCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C16H17Cl2N5O2/c17-11-4-3-10(7-12(11)18)8-19-16-21-14-13(15(25)22-16)23(9-20-14)5-1-2-6-24/h3-4,7,9,24H,1-2,5-6,8H2,(H2,19,21,22,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160343 (Acetic acid 4-[2-(3,4-dichloro-benzylamino)-6-oxo-...) Show SMILES CC(=O)OCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H19Cl2N5O3/c1-11(26)28-7-3-2-6-25-10-22-16-15(25)17(27)24-18(23-16)21-9-12-4-5-13(19)14(20)8-12/h4-5,8,10H,2-3,6-7,9H2,1H3,(H2,21,23,24,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160360 (2-(3,4-Dichloro-benzylamino)-7-(5-methanesulfinyl-...) Show SMILES CS(=O)CCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H21Cl2N5O2S/c1-28(27)8-4-2-3-7-25-11-22-16-15(25)17(26)24-18(23-16)21-10-12-5-6-13(19)14(20)9-12/h5-6,9,11H,2-4,7-8,10H2,1H3,(H2,21,23,24,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160356 (2-(3,4-Dichloro-benzylamino)-7-(5-methoxy-pentyl)-...) Show SMILES COCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H21Cl2N5O2/c1-27-8-4-2-3-7-25-11-22-16-15(25)17(26)24-18(23-16)21-10-12-5-6-13(19)14(20)9-12/h5-6,9,11H,2-4,7-8,10H2,1H3,(H2,21,23,24,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160341 (2-(3,4-Dichloro-benzylamino)-7-(2-ethoxy-ethyl)-1,...) Show SMILES CCOCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C16H17Cl2N5O2/c1-2-25-6-5-23-9-20-14-13(23)15(24)22-16(21-14)19-8-10-3-4-11(17)12(18)7-10/h3-4,7,9H,2,5-6,8H2,1H3,(H2,19,21,22,24)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160350 (Acetic acid (R)-5-[2-(3,4-dichloro-benzylamino)-6-...) Show SMILES C[C@H](CCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12)OC(C)=O Show InChI InChI=1S/C20H23Cl2N5O3/c1-12(30-13(2)28)5-3-4-8-27-11-24-18-17(27)19(29)26-20(25-18)23-10-14-6-7-15(21)16(22)9-14/h6-7,9,11-12H,3-5,8,10H2,1-2H3,(H2,23,25,26,29)/t12-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160356 (2-(3,4-Dichloro-benzylamino)-7-(5-methoxy-pentyl)-...) Show SMILES COCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H21Cl2N5O2/c1-27-8-4-2-3-7-25-11-22-16-15(25)17(26)24-18(23-16)21-10-12-5-6-13(19)14(20)9-12/h5-6,9,11H,2-4,7-8,10H2,1H3,(H2,21,23,24,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160353 (2-(3,4-Dichloro-benzylamino)-7-(5-methanesulfonyl-...) Show SMILES CS(=O)(=O)CCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H21Cl2N5O3S/c1-29(27,28)8-4-2-3-7-25-11-22-16-15(25)17(26)24-18(23-16)21-10-12-5-6-13(19)14(20)9-12/h5-6,9,11H,2-4,7-8,10H2,1H3,(H2,21,23,24,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160345 (2-(3,4-Dichloro-benzylamino)-7-(5-hydroxy-pentyl)-...) Show SMILES OCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C17H19Cl2N5O2/c18-12-5-4-11(8-13(12)19)9-20-17-22-15-14(16(26)23-17)24(10-21-15)6-2-1-3-7-25/h4-5,8,10,25H,1-3,6-7,9H2,(H2,20,22,23,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160360 (2-(3,4-Dichloro-benzylamino)-7-(5-methanesulfinyl-...) Show SMILES CS(=O)CCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H21Cl2N5O2S/c1-28(27)8-4-2-3-7-25-11-22-16-15(25)17(26)24-18(23-16)21-10-12-5-6-13(19)14(20)9-12/h5-6,9,11H,2-4,7-8,10H2,1H3,(H2,21,23,24,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160355 (CHEMBL181398 | Isobutyric acid 5-[2-(3,4-dichloro-...) Show SMILES CC(C)C(=O)OCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C21H25Cl2N5O3/c1-13(2)20(30)31-9-5-3-4-8-28-12-25-18-17(28)19(29)27-21(26-18)24-11-14-6-7-15(22)16(23)10-14/h6-7,10,12-13H,3-5,8-9,11H2,1-2H3,(H2,24,26,27,29)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160346 (2-(3,4-Dichloro-benzylamino)-7-[2-(2-hydroxy-ethox...) Show SMILES OCCOCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C16H17Cl2N5O3/c17-11-2-1-10(7-12(11)18)8-19-16-21-14-13(15(25)22-16)23(9-20-14)3-5-26-6-4-24/h1-2,7,9,24H,3-6,8H2,(H2,19,21,22,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160343 (Acetic acid 4-[2-(3,4-dichloro-benzylamino)-6-oxo-...) Show SMILES CC(=O)OCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H19Cl2N5O3/c1-11(26)28-7-3-2-6-25-10-22-16-15(25)17(27)24-18(23-16)21-9-12-4-5-13(19)14(20)8-12/h4-5,8,10H,2-3,6-7,9H2,1H3,(H2,21,23,24,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160347 (4-[2-(3,4-Dichloro-benzylamino)-6-oxo-1,6-dihydro-...) Show SMILES OC(=O)CCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C16H15Cl2N5O3/c17-10-4-3-9(6-11(10)18)7-19-16-21-14-13(15(26)22-16)23(8-20-14)5-1-2-12(24)25/h3-4,6,8H,1-2,5,7H2,(H,24,25)(H2,19,21,22,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160338 (4-[2-(3,4-Dichloro-benzylamino)-6-oxo-1,6-dihydro-...) Show SMILES CCOC(=O)CCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H19Cl2N5O3/c1-2-28-14(26)4-3-7-25-10-22-16-15(25)17(27)24-18(23-16)21-9-11-5-6-12(19)13(20)8-11/h5-6,8,10H,2-4,7,9H2,1H3,(H2,21,23,24,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA topoisomerase 3 (Bacillus subtilis)	BDBM50028339 (6-(3-Chloromethyl-4-methyl-phenylamino)-1H-pyrimid...) Show SMILES Cc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1CCl Show InChI InChI=1S/C12H12ClN3O2/c1-7-2-3-9(4-8(7)6-13)14-10-5-11(17)16-12(18)15-10/h2-5H,6H2,1H3,(H3,14,15,16,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160347 (4-[2-(3,4-Dichloro-benzylamino)-6-oxo-1,6-dihydro-...) Show SMILES OC(=O)CCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C16H15Cl2N5O3/c17-10-4-3-9(6-11(10)18)7-19-16-21-14-13(15(26)22-16)23(8-20-14)5-1-2-12(24)25/h3-4,6,8H,1-2,5,7H2,(H,24,25)(H2,19,21,22,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160352 (2-(3,4-Dichloro-benzylamino)-7-(5-methylsulfanyl-p...) Show SMILES CSCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H21Cl2N5OS/c1-27-8-4-2-3-7-25-11-22-16-15(25)17(26)24-18(23-16)21-10-12-5-6-13(19)14(20)9-12/h5-6,9,11H,2-4,7-8,10H2,1H3,(H2,21,23,24,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA topoisomerase 3 (Bacillus subtilis)	BDBM50077606 (6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...) Show SMILES CCc1cc(Nc2cc(=O)[nH]c(=O)[nH]2)ccc1C Show InChI InChI=1S/C13H15N3O2/c1-3-9-6-10(5-4-8(9)2)14-11-7-12(17)16-13(18)15-11/h4-7H,3H2,1-2H3,(H3,14,15,16,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160351 (2-(3,4-Dichloro-benzylamino)-7-(4-hydroxy-butyl)-1...) Show SMILES OCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C16H17Cl2N5O2/c17-11-4-3-10(7-12(11)18)8-19-16-21-14-13(15(25)22-16)23(9-20-14)5-1-2-6-24/h3-4,7,9,24H,1-2,5-6,8H2,(H2,19,21,22,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160352 (2-(3,4-Dichloro-benzylamino)-7-(5-methylsulfanyl-p...) Show SMILES CSCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H21Cl2N5OS/c1-27-8-4-2-3-7-25-11-22-16-15(25)17(26)24-18(23-16)21-10-12-5-6-13(19)14(20)9-12/h5-6,9,11H,2-4,7-8,10H2,1H3,(H2,21,23,24,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
Thymidine kinase (Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)	BDBM50366681 (BRIVUDINE | BVDU | Bridic | Brivox | Brivudin | Br...) Show SMILES OC[C@H]1O[C@H](C[C@@H]1O)n1cc(C=CBr)c(=O)[nH]c1=O |r,w:12.13| Show InChI InChI=1S/C11H13BrN2O5/c12-2-1-6-4-14(11(18)13-10(6)17)9-3-7(16)8(5-15)19-9/h1-2,4,7-9,15-16H,3,5H2,(H,13,17,18)/t7-,8+,9+/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MMDB PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibition of Herpes simplex virus 1 recombinant thymidine kinase				Antimicrob Agents Chemother 51: 2028-34 (2007) Article DOI: 10.1128/AAC.01284-06 BindingDB Entry DOI: 10.7270/Q2RN38R9
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160357 (4-[2-(3,4-Dichloro-benzylamino)-6-oxo-1,6-dihydro-...) Show SMILES OC(=O)CCCn1cnc2c1nc(NCc1ccc(Cl)c(Cl)c1)[nH]c2=O Show InChI InChI=1S/C16H15Cl2N5O3/c17-10-4-3-9(6-11(10)18)7-19-16-21-14-13(15(26)22-16)20-8-23(14)5-1-2-12(24)25/h3-4,6,8H,1-2,5,7H2,(H,24,25)(H2,19,21,22,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA topoisomerase 3 (Bacillus subtilis)	BDBM50028339 (6-(3-Chloromethyl-4-methyl-phenylamino)-1H-pyrimid...) Show SMILES Cc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1CCl Show InChI InChI=1S/C12H12ClN3O2/c1-7-2-3-9(4-8(7)6-13)14-10-5-11(17)16-12(18)15-10/h2-5H,6H2,1H3,(H3,14,15,16,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA topoisomerase 3 (Bacillus subtilis)	BDBM50028359 (6-(3-Iodo-4-methyl-phenylamino)-1H-pyrimidine-2,4-...) Show SMILES Cc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1I Show InChI InChI=1S/C11H10IN3O2/c1-6-2-3-7(4-8(6)12)13-9-5-10(16)15-11(17)14-9/h2-5H,1H3,(H3,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160353 (2-(3,4-Dichloro-benzylamino)-7-(5-methanesulfonyl-...) Show SMILES CS(=O)(=O)CCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C18H21Cl2N5O3S/c1-29(27,28)8-4-2-3-7-25-11-22-16-15(25)17(26)24-18(23-16)21-10-12-5-6-13(19)14(20)9-12/h5-6,9,11H,2-4,7-8,10H2,1H3,(H2,21,23,24,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160358 (2-(3-Ethyl-4-methyl-phenylamino)-7-(5-hydroxy-pent...) Show SMILES CCc1cc(Nc2nc3ncn(CCCCCO)c3c(=O)[nH]2)ccc1C Show InChI InChI=1S/C19H25N5O2/c1-3-14-11-15(8-7-13(14)2)21-19-22-17-16(18(26)23-19)24(12-20-17)9-5-4-6-10-25/h7-8,11-12,25H,3-6,9-10H2,1-2H3,(H2,21,22,23,26)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50077606 (6-(3-Ethyl-4-methyl-phenylamino)-1H-pyrimidine-2,4...) Show SMILES CCc1cc(Nc2cc(=O)[nH]c(=O)[nH]2)ccc1C Show InChI InChI=1S/C13H15N3O2/c1-3-9-6-10(5-4-8(9)2)14-11-7-12(17)16-13(18)15-11/h4-7H,3H2,1-2H3,(H3,14,15,16,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III subunit alpha (Bacillus subtilis)	BDBM50160354 (2-(3,4-Dichloro-benzylamino)-1,9-dihydro-purin-6-o...) Show SMILES Clc1ccc(CNc2nc3nc[nH]c3c(=O)[nH]2)cc1Cl Show InChI InChI=1S/C12H9Cl2N5O/c13-7-2-1-6(3-8(7)14)4-15-12-18-10-9(11(20)19-12)16-5-17-10/h1-3,5H,4H2,(H3,15,16,17,18,19,20)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIE from Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA topoisomerase 3 (Bacillus subtilis)	BDBM50028342 (6-(3,4-Dichloro-phenylamino)-1H-pyrimidine-2,4-dio...) Show SMILES Clc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1Cl Show InChI InChI=1S/C10H7Cl2N3O2/c11-6-2-1-5(3-7(6)12)13-8-4-9(16)15-10(17)14-8/h1-4H,(H3,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160341 (2-(3,4-Dichloro-benzylamino)-7-(2-ethoxy-ethyl)-1,...) Show SMILES CCOCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C16H17Cl2N5O2/c1-2-25-6-5-23-9-20-14-13(23)15(24)22-16(21-14)19-8-10-3-4-11(17)12(18)7-10/h3-4,7,9H,2,5-6,8H2,1H3,(H2,19,21,22,24)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160355 (CHEMBL181398 | Isobutyric acid 5-[2-(3,4-dichloro-...) Show SMILES CC(C)C(=O)OCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C21H25Cl2N5O3/c1-13(2)20(30)31-9-5-3-4-8-28-12-25-18-17(28)19(29)27-21(26-18)24-11-14-6-7-15(22)16(23)10-14/h6-7,10,12-13H,3-5,8-9,11H2,1-2H3,(H2,24,26,27,29)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160346 (2-(3,4-Dichloro-benzylamino)-7-[2-(2-hydroxy-ethox...) Show SMILES OCCOCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c12 Show InChI InChI=1S/C16H17Cl2N5O3/c17-11-2-1-10(7-12(11)18)8-19-16-21-14-13(15(25)22-16)23(9-20-14)3-5-26-6-4-24/h1-2,7,9,24H,3-6,8H2,(H2,19,21,22,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA topoisomerase 3 (Bacillus subtilis)	BDBM50028359 (6-(3-Iodo-4-methyl-phenylamino)-1H-pyrimidine-2,4-...) Show SMILES Cc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1I Show InChI InChI=1S/C11H10IN3O2/c1-6-2-3-7(4-8(6)12)13-9-5-10(16)15-11(17)14-9/h2-5H,1H3,(H3,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160349 (6-(4-Chloro-3-chloromethyl-benzylamino)-1H-pyrimid...) Show SMILES ClCc1cc(CNc2cc(=O)[nH]c(=O)[nH]2)ccc1Cl Show InChI InChI=1S/C12H11Cl2N3O2/c13-5-8-3-7(1-2-9(8)14)6-15-10-4-11(18)17-12(19)16-10/h1-4H,5-6H2,(H3,15,16,17,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA topoisomerase 3 (Bacillus subtilis)	BDBM50022163 (6-(Indan-5-ylamino)-1H-pyrimidine-2,4-dione | CHEM...) Show SMILES O=c1cc(Nc2ccc3CCCc3c2)[nH]c(=O)[nH]1 Show InChI InChI=1S/C13H13N3O2/c17-12-7-11(15-13(18)16-12)14-10-5-4-8-2-1-3-9(8)6-10/h4-7H,1-3H2,(H3,14,15,16,17,18)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160361 (2-(3-Ethyl-4-methyl-phenylamino)-7-(4-hydroxy-buty...) Show SMILES CCc1cc(Nc2nc3ncn(CCCCO)c3c(=O)[nH]2)ccc1C Show InChI InChI=1S/C18H23N5O2/c1-3-13-10-14(7-6-12(13)2)20-18-21-16-15(17(25)22-18)23(11-19-16)8-4-5-9-24/h6-7,10-11,24H,3-5,8-9H2,1-2H3,(H2,20,21,22,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA topoisomerase 3 (Bacillus subtilis)	BDBM50028341 (6-(3-Chloro-4-methyl-phenylamino)-1H-pyrimidine-2,...) Show SMILES Cc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1Cl Show InChI InChI=1S/C11H10ClN3O2/c1-6-2-3-7(4-8(6)12)13-9-5-10(16)15-11(17)14-9/h2-5H,1H3,(H3,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis DNA topoisomerase III (wild type).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA polymerase III PolC-type (Bacillus subtilis)	BDBM50160354 (2-(3,4-Dichloro-benzylamino)-1,9-dihydro-purin-6-o...) Show SMILES Clc1ccc(CNc2nc3nc[nH]c3c(=O)[nH]2)cc1Cl Show InChI InChI=1S/C12H9Cl2N5O/c13-7-2-1-6(3-8(7)14)4-15-12-18-10-9(11(20)19-12)16-5-17-10/h1-3,5H,4H2,(H3,15,16,17,18,19,20)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GLSynthesis Inc. Curated by ChEMBL					Assay Description Inhibitory constant against DNA polymerases IIIC produced by Bacillus subtilis; (a)				Bioorg Med Chem Lett 15: 729-32 (2005) Article DOI: 10.1016/j.bmcl.2004.11.016 BindingDB Entry DOI: 10.7270/Q2125S58
					More data for this Ligand-Target Pair
DNA topoisomerase 3 (Bacillus subtilis)	BDBM50028341 (6-(3-Chloro-4-methyl-phenylamino)-1H-pyrimidine-2,...) Show SMILES Cc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1Cl Show InChI InChI=1S/C11H10ClN3O2/c1-6-2-3-7(4-8(6)12)13-9-5-10(16)15-11(17)14-9/h2-5H,1H3,(H3,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	839	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair
DNA topoisomerase 3 (Bacillus subtilis)	BDBM50028327 (6-(4-Bromo-3-methyl-phenylamino)-1H-pyrimidine-2,4...) Show SMILES Cc1cc(Nc2cc(=O)[nH]c(=O)[nH]2)ccc1Br Show InChI InChI=1S/C11H10BrN3O2/c1-6-4-7(2-3-8(6)12)13-9-5-10(16)15-11(17)14-9/h2-5H,1H3,(H3,13,14,15,16,17)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	849	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition constant against Bacillus subtilis azp-12 DNA topoisomerase III (mutant enzyme).				J Med Chem 27: 181-5 (1984) BindingDB Entry DOI: 10.7270/Q2Q241FK
					More data for this Ligand-Target Pair

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