Compile Data Set for Download or QSAR

Found 38 hits with Last Name = 'hand' and Initial = 'jm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50016627 (C,C,C-Trifluoro-N-[7-(quinolin-2-ylmethoxy)-naphth...) Show SMILES FC(F)(F)S(=O)(=O)Nc1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1 Show InChI InChI=1S/C21H15F3N2O3S/c22-21(23,24)30(27,28)26-17-8-5-14-7-10-19(12-16(14)11-17)29-13-18-9-6-15-3-1-2-4-20(15)25-18/h1-12,26H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration of the compound to inhibit 5-lipoxygenase in the rat				J Med Chem 32: 1176-83 (1989) BindingDB Entry DOI: 10.7270/Q2833R1T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50012434 ((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...) Show SMILES CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H25NO2/c1-2-3-4-12-22(24)18-9-7-10-20(15-18)25-16-19-14-13-17-8-5-6-11-21(17)23-19/h5-11,13-15,22,24H,2-4,12,16H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50012434 ((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...) Show SMILES CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H25NO2/c1-2-3-4-12-22(24)18-9-7-10-20(15-18)25-16-19-14-13-17-8-5-6-11-21(17)23-19/h5-11,13-15,22,24H,2-4,12,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025771 (CHEMBL338408 | N-[3-(Benzothiazol-2-ylmethoxy)-phe...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2nc3ccccc3s2)c1 Show InChI InChI=1S/C19H18N2O5S/c1-25-19(23)10-9-18(22)21(24)13-5-4-6-14(11-13)26-12-17-20-15-7-2-3-8-16(15)27-17/h2-8,11,24H,9-10,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006801 (CHEMBL287012 | N-Hydroxy-N-[3-(quinolin-2-ylmethox...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H20N2O5/c1-27-21(25)12-11-20(24)23(26)17-6-4-7-18(13-17)28-14-16-10-9-15-5-2-3-8-19(15)22-16/h2-10,13,26H,11-12,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006801 (CHEMBL287012 | N-Hydroxy-N-[3-(quinolin-2-ylmethox...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H20N2O5/c1-27-21(25)12-11-20(24)23(26)17-6-4-7-18(13-17)28-14-16-10-9-15-5-2-3-8-19(15)22-16/h2-10,13,26H,11-12,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration that produces 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006806 (C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...) Show SMILES FC(F)(F)S(=O)(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C17H13F3N2O3S/c18-17(19,20)26(23,24)22-13-5-3-6-15(10-13)25-11-14-9-8-12-4-1-2-7-16(12)21-14/h1-10,22H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration for 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50006822 (1,1-Diethyl-3-{2-hydroxy-2-[3-(quinolin-2-ylmethox...) Show SMILES CCN(CC)C(=O)N(C)C[C@H](O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C24H29N3O3/c1-4-27(5-2)24(29)26(3)16-23(28)19-10-8-11-21(15-19)30-17-20-14-13-18-9-6-7-12-22(18)25-20/h6-15,23,28H,4-5,16-17H2,1-3H3/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50006806 (C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...) Show SMILES FC(F)(F)S(=O)(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C17H13F3N2O3S/c18-17(19,20)26(23,24)22-13-5-3-6-15(10-13)25-11-14-9-8-12-4-1-2-7-16(12)21-14/h1-10,22H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration to inhibit Prostaglandin G/H synthase in the rat				J Med Chem 32: 1176-83 (1989) BindingDB Entry DOI: 10.7270/Q2833R1T
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006820 (2-[3-(1H-Tetrazol-5-ylmethyl)-phenoxymethyl]-quino...) Show SMILES C(Oc1cccc(Cc2nnn[nH]2)c1)c1ccc2ccccc2n1 Show InChI InChI=1S/C18H15N5O/c1-2-7-17-14(5-1)8-9-15(19-17)12-24-16-6-3-4-13(10-16)11-18-20-22-23-21-18/h1-10H,11-12H2,(H,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration that produces 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006806 (C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...) Show SMILES FC(F)(F)S(=O)(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C17H13F3N2O3S/c18-17(19,20)26(23,24)22-13-5-3-6-15(10-13)25-11-14-9-8-12-4-1-2-7-16(12)21-14/h1-10,22H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration of the compound to inhibit 5-lipoxygenase in the rat				J Med Chem 32: 1176-83 (1989) BindingDB Entry DOI: 10.7270/Q2833R1T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50012434 ((REV-5,901)1-[3-(Quinolin-2-ylmethoxy)-phenyl]-hex...) Show SMILES CCCCCC(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H25NO2/c1-2-3-4-12-22(24)18-9-7-10-20(15-18)25-16-19-14-13-17-8-5-6-11-21(17)23-19/h5-11,13-15,22,24H,2-4,12,16H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit Prostaglandin G/H synthase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006821 (4-Methyl-N-[3-(quinolin-2-ylmethoxy)-benzoyl]-benz...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C24H20N2O4S/c1-17-9-13-22(14-10-17)31(28,29)26-24(27)19-6-4-7-21(15-19)30-16-20-12-11-18-5-2-3-8-23(18)25-20/h2-15H,16H2,1H3,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration that produces 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase.				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025770 (CHEMBL334848 | N-[3-(1-Methyl-1H-benzoimidazol-2-y...) Show SMILES COC(=O)CCC(=O)Nc1cccc(OCc2nc3ccccc3n2C)c1 Show InChI InChI=1S/C20H21N3O4/c1-23-17-9-4-3-8-16(17)22-18(23)13-27-15-7-5-6-14(12-15)21-19(24)10-11-20(25)26-2/h3-9,12H,10-11,13H2,1-2H3,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50006806 (C,C,C-Trifluoro-N-[3-(quinolin-2-ylmethoxy)-phenyl...) Show SMILES FC(F)(F)S(=O)(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C17H13F3N2O3S/c18-17(19,20)26(23,24)22-13-5-3-6-15(10-13)25-11-14-9-8-12-4-1-2-7-16(12)21-14/h1-10,22H,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration for 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by Prostaglandin G/H synthase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50016627 (C,C,C-Trifluoro-N-[7-(quinolin-2-ylmethoxy)-naphth...) Show SMILES FC(F)(F)S(=O)(=O)Nc1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1 Show InChI InChI=1S/C21H15F3N2O3S/c22-21(23,24)30(27,28)26-17-8-5-14-7-10-19(12-16(14)11-17)29-13-18-9-6-15-3-1-2-4-20(15)25-18/h1-12,26H,13H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Inhibitory concentration to inhibit Prostaglandin G/H synthase in the rat				J Med Chem 32: 1176-83 (1989) BindingDB Entry DOI: 10.7270/Q2833R1T
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50006821 (4-Methyl-N-[3-(quinolin-2-ylmethoxy)-benzoyl]-benz...) Show SMILES Cc1ccc(cc1)S(=O)(=O)NC(=O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C24H20N2O4S/c1-17-9-13-22(14-10-17)31(28,29)26-24(27)19-6-4-7-21(15-19)30-16-20-12-11-18-5-2-3-8-23(18)25-20/h2-15H,16H2,1H3,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by Prostaglandin G/H synthase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025772 (1-[3-(Benzothiazol-2-ylmethoxy)-phenyl]-5-oxo-pyrr...) Show SMILES COC(=O)C1CN(C(=O)C1)c1cccc(OCc2nc3ccccc3s2)c1 Show InChI InChI=1S/C20H18N2O4S/c1-25-20(24)13-9-19(23)22(11-13)14-5-4-6-15(10-14)26-12-18-21-16-7-2-3-8-17(16)27-18/h2-8,10,13H,9,11-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006813 (CHEMBL79453 | N-Methoxy-2-[3-(quinolin-2-ylmethoxy...) Show SMILES CONC(=O)Cc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C19H18N2O3/c1-23-21-19(22)12-14-5-4-7-17(11-14)24-13-16-10-9-15-6-2-3-8-18(15)20-16/h2-11H,12-13H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration for 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025766 (CHEMBL130819 | N-[3-(Benzothiazol-2-ylmethoxy)-phe...) Show SMILES COC(=O)CCC(=O)Nc1cccc(OCc2nc3ccccc3s2)c1 Show InChI InChI=1S/C19H18N2O4S/c1-24-19(23)10-9-17(22)20-13-5-4-6-14(11-13)25-12-18-21-15-7-2-3-8-16(15)26-18/h2-8,11H,9-10,12H2,1H3,(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the rat Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025769 (CHEMBL341255 | N-[3-(Benzothiazol-2-ylmethoxy)-phe...) Show SMILES COC(=O)CC(=O)Nc1cccc(OCc2nc3ccccc3s2)c1 Show InChI InChI=1S/C18H16N2O4S/c1-23-18(22)10-16(21)19-12-5-4-6-13(9-12)24-11-17-20-14-7-2-3-8-15(14)25-17/h2-9H,10-11H2,1H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025767 (CHEMBL131423 | N-[3-(Benzofuran-2-ylmethoxy)-pheny...) Show SMILES COC(=O)CCC(=O)Nc1cccc(OCc2cc3ccccc3o2)c1 Show InChI InChI=1S/C20H19NO5/c1-24-20(23)10-9-19(22)21-15-6-4-7-16(12-15)25-13-17-11-14-5-2-3-8-18(14)26-17/h2-8,11-12H,9-10,13H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006816 ((LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol...) Show SMILES CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O Show InChI InChI=1S/C16H22N4O3/c1-3-6-13-14(9-8-12(11(2)21)16(13)22)23-10-5-4-7-15-17-19-20-18-15/h8-9,22H,3-7,10H2,1-2H3,(H,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50006816 ((LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol...) Show SMILES CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O Show InChI InChI=1S/C16H22N4O3/c1-3-6-13-14(9-8-12(11(2)21)16(13)22)23-10-5-4-7-15-17-19-20-18-15/h8-9,22H,3-7,10H2,1-2H3,(H,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration for 50% inhibition of A-23,187-stimulated radiolabelled 5-HETE and TXB2 synthesis by PMN 5-lipoxygenase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50006816 ((LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol...) Show SMILES CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O Show InChI InChI=1S/C16H22N4O3/c1-3-6-13-14(9-8-12(11(2)21)16(13)22)23-10-5-4-7-15-17-19-20-18-15/h8-9,22H,3-7,10H2,1-2H3,(H,17,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025764 (5-Oxo-1-[3-(quinolin-2-ylmethoxy)-phenyl]-pyrrolid...) Show SMILES COC(=O)C1CN(C(=O)C1)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C22H20N2O4/c1-27-22(26)16-11-21(25)24(13-16)18-6-4-7-19(12-18)28-14-17-10-9-15-5-2-3-8-20(15)23-17/h2-10,12,16H,11,13-14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50405505 (CHEMBL2115108) Show SMILES CN1C[C@H](OC1=O)c1cccc(OCc2ccc3ccccc3n2)c1 |r| Show InChI InChI=1S/C20H18N2O3/c1-22-12-19(25-20(22)23)15-6-4-7-17(11-15)24-13-16-10-9-14-5-2-3-8-18(14)21-16/h2-11,19H,12-13H2,1H3/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit 5-lipoxygenase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025762 (CHEMBL130717 | N-[3-(Benzothiazol-2-ylmethoxy)-phe...) Show SMILES COC(=O)CCC(=O)N(C)c1cccc(OCc2nc3ccccc3s2)c1 Show InChI InChI=1S/C20H20N2O4S/c1-22(19(23)10-11-20(24)25-2)14-6-5-7-15(12-14)26-13-18-21-16-8-3-4-9-17(16)27-18/h3-9,12H,10-11,13H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025765 (CHEMBL130864 | N-[3-(Benzothiazol-2-yloxy)-phenyl]...) Show SMILES COC(=O)CCC(=O)Nc1cccc(Oc2nc3ccccc3s2)c1 Show InChI InChI=1S/C18H16N2O4S/c1-23-17(22)10-9-16(21)19-12-5-4-6-13(11-12)24-18-20-14-7-2-3-8-15(14)25-18/h2-8,11H,9-10H2,1H3,(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	2.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50022196 (CHEMBL288778 | N-[3-(Quinolin-2-ylmethoxy)-phenyl]...) Show SMILES COC(=O)CCC(=O)Nc1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H20N2O4/c1-26-21(25)12-11-20(24)23-16-6-4-7-18(13-16)27-14-17-10-9-15-5-2-3-8-19(15)22-17/h2-10,13H,11-12,14H2,1H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025763 (1-[3-(Benzooxazol-2-ylmethoxy)-phenyl]-5-oxo-pyrro...) Show SMILES COC(=O)C1CN(C(=O)C1)c1cccc(OCc2nc3ccccc3o2)c1 Show InChI InChI=1S/C20H18N2O5/c1-25-20(24)13-9-19(23)22(11-13)14-5-4-6-15(10-14)26-12-18-21-16-7-2-3-8-17(16)27-18/h2-8,10,13H,9,11-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50006801 (CHEMBL287012 | N-Hydroxy-N-[3-(quinolin-2-ylmethox...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H20N2O5/c1-27-21(25)12-11-20(24)23(26)17-6-4-7-18(13-17)28-14-16-10-9-15-5-2-3-8-19(15)22-16/h2-10,13,26H,11-12,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit the rat PMN (polymorphonuclear leukocyte) CO (cyclo-oxygenase) in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50006801 (CHEMBL287012 | N-Hydroxy-N-[3-(quinolin-2-ylmethox...) Show SMILES COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C21H20N2O5/c1-27-21(25)12-11-20(24)23(26)17-6-4-7-18(13-17)28-14-16-10-9-15-5-2-3-8-19(15)22-16/h2-10,13,26H,11-12,14H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration that produces 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by PMN (Prostaglandin G/H synthase).				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50006816 ((LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol...) Show SMILES CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O Show InChI InChI=1S/C16H22N4O3/c1-3-6-13-14(9-8-12(11(2)21)16(13)22)23-10-5-4-7-15-17-19-20-18-15/h8-9,22H,3-7,10H2,1-2H3,(H,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration for 50% inhibition of A-23187-stimulated radiolabeled 5-HETE and TXB2 synthesis by Prostaglandin G/H synthase				J Med Chem 33: 240-5 (1990) BindingDB Entry DOI: 10.7270/Q24Q7T0P
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50006816 ((LY-171883)1-{2-Hydroxy-3-propyl-4-[4-(1H-tetrazol...) Show SMILES CCCc1c(OCCCCc2nnn[nH]2)ccc(C(C)=O)c1O Show InChI InChI=1S/C16H22N4O3/c1-3-6-13-14(9-8-12(11(2)21)16(13)22)23-10-5-4-7-15-17-19-20-18-15/h8-9,22H,3-7,10H2,1-2H3,(H,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit Prostaglandin G/H synthase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rattus norvegicus)	BDBM50025768 (CHEMBL131323 | N-[3-(Benzooxazol-2-ylmethoxy)-phen...) Show SMILES COC(=O)CCC(=O)Nc1cccc(OCc2nc3ccccc3o2)c1 Show InChI InChI=1S/C19H18N2O5/c1-24-19(23)10-9-17(22)20-13-5-4-6-14(11-13)25-12-18-21-15-7-2-3-8-16(15)26-18/h2-8,11H,9-10,12H2,1H3,(H,20,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Ability to inhibit Lipoxygenase in vitro was determined				J Med Chem 30: 400-5 (1987) BindingDB Entry DOI: 10.7270/Q2K936JS
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50006822 (1,1-Diethyl-3-{2-hydroxy-2-[3-(quinolin-2-ylmethox...) Show SMILES CCN(CC)C(=O)N(C)C[C@H](O)c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C24H29N3O3/c1-4-27(5-2)24(29)26(3)16-23(28)19-10-8-11-21(15-19)30-17-20-14-13-18-9-6-7-12-22(18)25-20/h6-15,23,28H,4-5,16-17H2,1-3H3/t23-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit Prostaglandin G/H synthase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Homo sapiens (Human))	BDBM50405505 (CHEMBL2115108) Show SMILES CN1C[C@H](OC1=O)c1cccc(OCc2ccc3ccccc3n2)c1 |r| Show InChI InChI=1S/C20H18N2O3/c1-22-12-19(25-20(22)23)15-6-4-7-17(11-15)24-13-16-10-9-14-5-2-3-8-18(14)21-16/h2-11,19H,12-13H2,1H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Laboratories Curated by ChEMBL					Assay Description Ability to inhibit Prostaglandin G/H synthase in guinea pig				J Med Chem 30: 2087-93 (1987) BindingDB Entry DOI: 10.7270/Q2FQ9VMQ
					More data for this Ligand-Target Pair