Compile Data Set for Download or QSAR

Found 138 hits with Last Name = 'washecheck' and Initial = 'jp'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50547324 (CHEMBL4754102) Show SMILES COc1cccc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50547312 (CHEMBL4744634) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(OC3CCOC3)cccc12)C#N Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50547309 (CHEMBL4753189) Show SMILES CC(C)Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50547305 (CHEMBL4761695) Show SMILES [2H]C([2H])([2H])Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50547322 (CHEMBL4745777) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(cccc12)N1CCOCC1)C#N Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531687 (CHEMBL4445682) Show SMILES COc1cc(ccc1OCC1CC1)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C21H19F3N4O4/c1-30-19-8-14(4-7-18(19)31-10-13-2-3-13)20(29)27-16-9-15(32-21(22,23)24)5-6-17(16)28-12-25-11-26-28/h4-9,11-13H,2-3,10H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	347	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531687 (CHEMBL4445682) Show SMILES COc1cc(ccc1OCC1CC1)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C21H19F3N4O4/c1-30-19-8-14(4-7-18(19)31-10-13-2-3-13)20(29)27-16-9-15(32-21(22,23)24)5-6-17(16)28-12-25-11-26-28/h4-9,11-13H,2-3,10H2,1H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523865 (CHEMBL4476495) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1ccnc1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(9-17(16)29-2)18-25-26-19(30-18)14-10-13(31-20(21,22)23)4-5-15(14)27-8-7-24-11-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50280368 (CHEMBL4176971) Show SMILES COc1ccc(cc1OC)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C18H15F3N4O4/c1-27-15-6-3-11(7-16(15)28-2)17(26)24-13-8-12(29-18(19,20)21)4-5-14(13)25-10-22-9-23-25/h3-10H,1-2H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	759	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50280368 (CHEMBL4176971) Show SMILES COc1ccc(cc1OC)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C18H15F3N4O4/c1-27-15-6-3-11(7-16(15)28-2)17(26)24-13-8-12(29-18(19,20)21)4-5-14(13)25-10-22-9-23-25/h3-10H,1-2H3,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531689 (CHEMBL4483431) Show SMILES COc1cc(F)c(OCCNc2cc(OC(F)(F)F)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C19H18F4N4O4/c1-28-17-8-13(20)16(9-18(17)29-2)30-6-5-25-14-7-12(31-19(21,22)23)3-4-15(14)27-11-24-10-26-27/h3-4,7-11,25H,5-6H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523871 (CHEMBL4551424) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1N1CCOCC1 Show InChI InChI=1S/C21H20F3N3O5/c1-28-17-6-3-13(11-18(17)29-2)19-25-26-20(31-19)15-12-14(32-21(22,23)24)4-5-16(15)27-7-9-30-10-8-27/h3-6,11-12H,7-10H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531689 (CHEMBL4483431) Show SMILES COc1cc(F)c(OCCNc2cc(OC(F)(F)F)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C19H18F4N4O4/c1-28-17-8-13(20)16(9-18(17)29-2)30-6-5-25-14-7-12(31-19(21,22)23)3-4-15(14)27-11-24-10-26-27/h3-4,7-11,25H,5-6H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531680 (CHEMBL4562432) Show SMILES COc1cc(ccc1OCC(C)C)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C21H21F3N4O4/c1-13(2)10-31-18-7-4-14(8-19(18)30-3)20(29)27-16-9-15(32-21(22,23)24)5-6-17(16)28-12-25-11-26-28/h4-9,11-13H,10H2,1-3H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531680 (CHEMBL4562432) Show SMILES COc1cc(ccc1OCC(C)C)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C21H21F3N4O4/c1-13(2)10-31-18-7-4-14(8-19(18)30-3)20(29)27-16-9-15(32-21(22,23)24)5-6-17(16)28-12-25-11-26-28/h4-9,11-13H,10H2,1-3H3,(H,27,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531678 (CHEMBL4526190) Show SMILES COc1cc(F)c(CCCNc2cc(OC(F)(F)F)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C20H20F4N4O3/c1-29-18-8-13(15(21)10-19(18)30-2)4-3-7-26-16-9-14(31-20(22,23)24)5-6-17(16)28-12-25-11-27-28/h5-6,8-12,26H,3-4,7H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523878 (CHEMBL4445828) Show SMILES COc1cc(ccc1OCC1CC1)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C22H18F3N5O4/c1-31-19-8-14(4-7-18(19)32-10-13-2-3-13)20-28-29-21(33-20)16-9-15(34-22(23,24)25)5-6-17(16)30-12-26-11-27-30/h4-9,11-13H,2-3,10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531678 (CHEMBL4526190) Show SMILES COc1cc(F)c(CCCNc2cc(OC(F)(F)F)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C20H20F4N4O3/c1-29-18-8-13(15(21)10-19(18)30-2)4-3-7-26-16-9-14(31-20(22,23)24)5-6-17(16)28-12-25-11-27-28/h5-6,8-12,26H,3-4,7H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523866 (CHEMBL4572513) Show SMILES COc1ccc(cc1OC)-c1noc(n1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C19H14F3N5O4/c1-28-15-6-3-11(7-16(15)29-2)17-25-18(31-26-17)13-8-12(30-19(20,21)22)4-5-14(13)27-10-23-9-24-27/h3-10H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523870 (CHEMBL4470938) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-c1ccnn1C Show InChI InChI=1S/C21H17F3N4O4/c1-28-16(8-9-25-28)14-6-5-13(32-21(22,23)24)11-15(14)20-27-26-19(31-20)12-4-7-17(29-2)18(10-12)30-3/h4-11H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531681 (CHEMBL4453525) Show SMILES COc1cc(ccc1OCC1CCC1)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C22H21F3N4O4/c1-31-20-9-15(5-8-19(20)32-11-14-3-2-4-14)21(30)28-17-10-16(33-22(23,24)25)6-7-18(17)29-13-26-12-27-29/h5-10,12-14H,2-4,11H2,1H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531681 (CHEMBL4453525) Show SMILES COc1cc(ccc1OCC1CCC1)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C22H21F3N4O4/c1-31-20-9-15(5-8-19(20)32-11-14-3-2-4-14)21(30)28-17-10-16(33-22(23,24)25)6-7-18(17)29-13-26-12-27-29/h5-10,12-14H,2-4,11H2,1H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523889 (CHEMBL4458158) Show SMILES COc1cc(ccc1OC1CCC1)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C22H18F3N5O4/c1-31-19-9-13(5-8-18(19)32-14-3-2-4-14)20-28-29-21(33-20)16-10-15(34-22(23,24)25)6-7-17(16)30-12-26-11-27-30/h5-12,14H,2-4H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523881 (CHEMBL4465794) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C19H14F3N5O4/c1-28-15-6-3-11(7-16(15)29-2)17-25-26-18(30-17)13-8-12(31-19(20,21)22)4-5-14(13)27-10-23-9-24-27/h3-10H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531691 (CHEMBL4463654) Show SMILES COc1ccc(CCCNc2cc(OC(F)(F)F)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C20H21F3N4O3/c1-28-18-8-5-14(10-19(18)29-2)4-3-9-25-16-11-15(30-20(21,22)23)6-7-17(16)27-13-24-12-26-27/h5-8,10-13,25H,3-4,9H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531691 (CHEMBL4463654) Show SMILES COc1ccc(CCCNc2cc(OC(F)(F)F)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C20H21F3N4O3/c1-28-18-8-5-14(10-19(18)29-2)4-3-9-25-16-11-15(30-20(21,22)23)6-7-17(16)27-13-24-12-26-27/h5-8,10-13,25H,3-4,9H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523863 (CHEMBL4552061) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cccn1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-7-4-12(10-17(16)29-2)18-25-26-19(30-18)14-11-13(31-20(21,22)23)5-6-15(14)27-9-3-8-24-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523884 (CHEMBL4442872) Show SMILES COc1ccc(cc1OC)-c1cnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-12(7-17(16)29-2)18-9-25-19(30-18)14-8-13(31-20(21,22)23)4-5-15(14)27-11-24-10-26-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50547328 (CHEMBL4752850) Show SMILES COc1c(F)c(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523879 (CHEMBL4467224) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-c1cn[nH]c1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-16-6-3-11(7-17(16)29-2)18-26-27-19(30-18)15-8-13(31-20(21,22)23)4-5-14(15)12-9-24-25-10-12/h3-10H,1-2H3,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523868 (CHEMBL4447704) Show SMILES COc1ccc(cc1OC)-c1nc(no1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C19H14F3N5O4/c1-28-15-6-3-11(7-16(15)29-2)18-25-17(26-31-18)13-8-12(30-19(20,21)22)4-5-14(13)27-10-23-9-24-27/h3-10H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531682 (CHEMBL4547249) Show SMILES COc1cc(ccc1OCC1CCCC1)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C23H23F3N4O4/c1-32-21-10-16(6-9-20(21)33-12-15-4-2-3-5-15)22(31)29-18-11-17(34-23(24,25)26)7-8-19(18)30-14-27-13-28-30/h6-11,13-15H,2-5,12H2,1H3,(H,29,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531682 (CHEMBL4547249) Show SMILES COc1cc(ccc1OCC1CCCC1)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C23H23F3N4O4/c1-32-21-10-16(6-9-20(21)33-12-15-4-2-3-5-15)22(31)29-18-11-17(34-23(24,25)26)7-8-19(18)30-14-27-13-28-30/h6-11,13-15H,2-5,12H2,1H3,(H,29,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50547326 (CHEMBL4779613) Show SMILES COc1c(F)ccc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531683 (CHEMBL4445412) Show SMILES COc1cc(ccc1OCc1ccccc1)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C24H19F3N4O4/c1-33-22-11-17(7-10-21(22)34-13-16-5-3-2-4-6-16)23(32)30-19-12-18(35-24(25,26)27)8-9-20(19)31-15-28-14-29-31/h2-12,14-15H,13H2,1H3,(H,30,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531683 (CHEMBL4445412) Show SMILES COc1cc(ccc1OCc1ccccc1)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C24H19F3N4O4/c1-33-22-11-17(7-10-21(22)34-13-16-5-3-2-4-6-16)23(32)30-19-12-18(35-24(25,26)27)8-9-20(19)31-15-28-14-29-31/h2-12,14-15H,13H2,1H3,(H,30,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50547305 (CHEMBL4761695) Show SMILES [2H]C([2H])([2H])Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-Pentazocine from human recombinant sigma 1 receptor incubated for 120 mins by scintillation counting analysis relative to contro...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523869 (CHEMBL4452758) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-c1cscn1 Show InChI InChI=1S/C20H14F3N3O4S/c1-27-16-6-3-11(7-17(16)28-2)18-25-26-19(29-18)14-8-12(30-20(21,22)23)4-5-13(14)15-9-31-10-24-15/h3-10H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50547325 (CHEMBL4752581) Show SMILES COc1ccc(F)c2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]nisoxetine from recombinant human Dopamine transporter after 120 mins by scintillation counting analysis				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523888 (CHEMBL4453831) Show SMILES COc1cc(cnc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C18H13F3N6O4/c1-28-14-5-10(7-23-17(14)29-2)15-25-26-16(30-15)12-6-11(31-18(19,20)21)3-4-13(12)27-9-22-8-24-27/h3-9H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523872 (CHEMBL4524757) Show SMILES COc1ccc(cc1OC)-c1nnc(o1)-c1cc(OC(F)(F)F)ccc1N1CCCCC1 Show InChI InChI=1S/C22H22F3N3O4/c1-29-18-9-6-14(12-19(18)30-2)20-26-27-21(31-20)16-13-15(32-22(23,24)25)7-8-17(16)28-10-4-3-5-11-28/h6-9,12-13H,3-5,10-11H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531686 (CHEMBL4467263) Show SMILES COc1ccc(CNc2cc(OC(F)(F)F)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C18H17F3N4O3/c1-26-16-6-3-12(7-17(16)27-2)9-23-14-8-13(28-18(19,20)21)4-5-15(14)25-11-22-10-24-25/h3-8,10-11,23H,9H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531686 (CHEMBL4467263) Show SMILES COc1ccc(CNc2cc(OC(F)(F)F)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C18H17F3N4O3/c1-26-16-6-3-12(7-17(16)27-2)9-23-14-8-13(28-18(19,20)21)4-5-15(14)25-11-22-10-24-25/h3-8,10-11,23H,9H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50523867 (CHEMBL4435790) Show SMILES COc1ccc(cc1OC)-c1coc(n1)-c1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C20H15F3N4O4/c1-28-17-6-3-12(7-18(17)29-2)15-9-30-19(26-15)14-8-13(31-20(21,22)23)4-5-16(14)27-11-24-10-25-27/h3-11H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as reduction in calcium mobilization incu...				Bioorg Med Chem Lett 29: 1211-1214 (2019) Article DOI: 10.1016/j.bmcl.2019.03.016 BindingDB Entry DOI: 10.7270/Q2WH2TDX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531690 (CHEMBL4442991) Show SMILES COc1ccc(CNc2cc(Cl)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C17H17ClN4O2/c1-23-16-6-3-12(7-17(16)24-2)9-20-14-8-13(18)4-5-15(14)22-11-19-10-21-22/h3-8,10-11,20H,9H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531690 (CHEMBL4442991) Show SMILES COc1ccc(CNc2cc(Cl)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C17H17ClN4O2/c1-23-16-6-3-12(7-17(16)24-2)9-20-14-8-13(18)4-5-15(14)22-11-19-10-21-22/h3-8,10-11,20H,9H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531677 (CHEMBL4557757) Show SMILES COc1ccc(CCCNc2cc(Cl)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C19H21ClN4O2/c1-25-18-8-5-14(10-19(18)26-2)4-3-9-22-16-11-15(20)6-7-17(16)24-13-21-12-23-24/h5-8,10-13,22H,3-4,9H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531684 (CHEMBL4467232) Show SMILES COc1cc(F)c(CCCNc2cc(Cl)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C19H20ClFN4O2/c1-26-18-8-13(15(21)10-19(18)27-2)4-3-7-23-16-9-14(20)5-6-17(16)25-12-22-11-24-25/h5-6,8-12,23H,3-4,7H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531685 (CHEMBL4563163) Show SMILES COc1cc(F)c(OCCNc2cc(Cl)ccc2-n2cncn2)cc1OC Show InChI InChI=1S/C18H18ClFN4O3/c1-25-17-8-13(20)16(9-18(17)26-2)27-6-5-22-14-7-12(19)3-4-15(14)24-11-21-10-23-24/h3-4,7-11,22H,5-6H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50531688 (CHEMBL4476165) Show SMILES COc1cc(ccc1OCC(C)(C)C)C(=O)Nc1cc(OC(F)(F)F)ccc1-n1cncn1 Show InChI InChI=1S/C22H23F3N4O4/c1-21(2,3)11-32-18-8-5-14(9-19(18)31-4)20(30)28-16-10-15(33-22(23,24)25)6-7-17(16)29-13-26-12-27-29/h5-10,12-13H,11H2,1-4H3,(H,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University School of Medicine Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells harboring Ga15 assessed as reduction in L-AP4-induced calcium flux preinc...				J Med Chem 62: 1690-1695 (2019) Article DOI: 10.1021/acs.jmedchem.8b01810 BindingDB Entry DOI: 10.7270/Q2QC070T
					More data for this Ligand-Target Pair

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