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Compile Data Set for Download or QSAR

Found 52 hits with Last Name = 'lotti' and Initial = 'js'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)
BDBM50583032
PNG
(CHEMBL5090386)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccc(Cl)cc1[N+]([O-])=O)C(O)=O |r|
PDB

KEGG

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UniChem
Article
PubMed
n/an/a 1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2B NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)
BDBM50583019
PNG
(CHEMBL5081008)
Show SMILES CCc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
PDB

KEGG

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n/an/a 1.00E+4n/an/an/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2B NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583021
PNG
(CHEMBL5091289)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc2ccccc12)C(O)=O |r|
PDB

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UniChem
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n/an/an/an/a 180n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583022
PNG
(CHEMBL5085583)
Show SMILES Cc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
PDB

KEGG

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n/an/an/an/a 220n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583023
PNG
(CHEMBL5081203)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Cl)C(O)=O |r|
PDB

KEGG

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n/an/an/an/a 260n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM18133
PNG
(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Show SMILES NCC(O)=O
Show InChI InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
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n/an/an/an/a 990n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM23167
PNG
((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Show SMILES N[C@H](CO)C(O)=O
Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
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n/an/an/an/a 1.00E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583024
PNG
(CHEMBL5087170)
Show SMILES COCc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
PDB

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n/an/an/an/a 3.10E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583025
PNG
(CHEMBL5093773)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccc(Cl)cc1)C(O)=O |r|
PDB

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n/an/an/an/a 4.30E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583026
PNG
(CHEMBL5072895)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1)C(O)=O |r|
PDB

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n/an/an/an/a 4.80E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583027
PNG
(CHEMBL5076681)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc(Cl)c1)C(O)=O |r|
PDB

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n/an/an/an/a 4.90E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583028
PNG
(CHEMBL5087550)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc(c1)C(F)(F)F)C(O)=O |r|
PDB

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n/an/an/an/a 6.60E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583029
PNG
(CHEMBL5081696)
Show SMILES CN(C)S(=O)(=O)c1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
PDB

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UniChem
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n/an/an/an/a 1.00E+4n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583030
PNG
(CHEMBL5083882)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccc(Cl)c(Cl)c1)C(O)=O |r|
PDB

KEGG

UniProtKB/SwissProt

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n/an/an/an/a 2.30E+4n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A


(Rattus norvegicus (Rat)-RAT)
BDBM50583031
PNG
(CHEMBL5081078)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Br)C(O)=O |r|
PDB

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n/an/an/an/a 53n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2A NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)
BDBM18133
PNG
(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Show SMILES NCC(O)=O
Show InChI InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
PDB

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n/an/an/an/a 240n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2B NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2B


(Rattus norvegicus (Rat)-RAT)
BDBM23167
PNG
((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Show SMILES N[C@H](CO)C(O)=O
Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
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n/an/an/an/a 620n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2B NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583031
PNG
(CHEMBL5081078)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Br)C(O)=O |r|
PDB

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UniProtKB/SwissProt

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n/an/an/an/a 36n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583020
PNG
(CHEMBL5087374)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1C(F)(F)F)C(O)=O |r|
PDB

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n/an/an/an/a 40n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583019
PNG
(CHEMBL5081008)
Show SMILES CCc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
PDB

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n/an/an/an/a 63n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583032
PNG
(CHEMBL5090386)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccc(Cl)cc1[N+]([O-])=O)C(O)=O |r|
PDB

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n/an/an/an/a 74n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583021
PNG
(CHEMBL5091289)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc2ccccc12)C(O)=O |r|
PDB

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n/an/an/an/a 110n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583023
PNG
(CHEMBL5081203)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Cl)C(O)=O |r|
PDB

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n/an/an/an/a 120n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583022
PNG
(CHEMBL5085583)
Show SMILES Cc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
PDB

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n/an/an/an/a 140n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM23167
PNG
((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Show SMILES N[C@H](CO)C(O)=O
Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
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n/an/an/an/a 190n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM18133
PNG
(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Show SMILES NCC(O)=O
Show InChI InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
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n/an/an/an/a 210n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583033
PNG
(CHEMBL5092220)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1\C=C\c1cccc(F)c1)C(O)=O |r|
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n/an/an/an/a 750n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583034
PNG
(CHEMBL5075942)
Show SMILES COc1ccc(cc1)-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
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n/an/an/an/a 1.30E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583027
PNG
(CHEMBL5076681)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc(Cl)c1)C(O)=O |r|
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n/an/an/an/a 1.30E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583024
PNG
(CHEMBL5087170)
Show SMILES COCc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
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n/an/an/an/a 1.60E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583025
PNG
(CHEMBL5093773)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccc(Cl)cc1)C(O)=O |r|
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n/an/an/an/a 1.70E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583028
PNG
(CHEMBL5087550)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc(c1)C(F)(F)F)C(O)=O |r|
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n/an/an/an/a 1.80E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583026
PNG
(CHEMBL5072895)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1)C(O)=O |r|
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n/an/an/an/a 2.90E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583035
PNG
(CHEMBL5091158)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc2OCCOc12)C(O)=O |r|
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n/an/an/an/a 3.90E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583036
PNG
(CHEMBL5079391)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1OCc1ccccc1)C(O)=O |r|
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n/an/an/an/a 4.00E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583030
PNG
(CHEMBL5083882)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccc(Cl)c(Cl)c1)C(O)=O |r|
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n/an/an/an/a 4.20E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583029
PNG
(CHEMBL5081696)
Show SMILES CN(C)S(=O)(=O)c1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
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n/an/an/an/a 4.80E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2C


(RAT-Rattus norvegicus (Rat))
BDBM50583037
PNG
(CHEMBL5079035)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1\C=C\c1ccccc1)C(O)=O |r|
PDB

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n/an/an/an/a 5.80E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2C NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50583031
PNG
(CHEMBL5081078)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Br)C(O)=O |r|
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n/an/an/an/a 80n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM18133
PNG
(2-aminoacetic acid | CHEMBL773 | Glycine | [14C]Gl...)
Show SMILES NCC(O)=O
Show InChI InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
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n/an/an/an/a 91n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50583019
PNG
(CHEMBL5081008)
Show SMILES CCc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
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n/an/an/an/a 150n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM23167
PNG
((2R)-2-amino-3-hydroxypropanoic acid | CHEMBL28512...)
Show SMILES N[C@H](CO)C(O)=O
Show InChI InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m1/s1
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n/an/an/an/a 150n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50583021
PNG
(CHEMBL5091289)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc2ccccc12)C(O)=O |r|
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n/an/an/an/a 230n/an/an/an/a


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Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50583022
PNG
(CHEMBL5085583)
Show SMILES Cc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
PDB

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n/an/an/an/a 260n/an/an/an/a


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Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50583023
PNG
(CHEMBL5081203)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1Cl)C(O)=O |r|
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n/an/an/an/a 270n/an/an/an/a


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Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50583024
PNG
(CHEMBL5087170)
Show SMILES COCc1ccccc1-c1ccc(o1)C(=O)NC[C@@H](N)C(O)=O |r|
PDB

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n/an/an/an/a 3.20E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50583026
PNG
(CHEMBL5072895)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccccc1)C(O)=O |r|
PDB

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n/an/an/an/a 4.30E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50583027
PNG
(CHEMBL5076681)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc(Cl)c1)C(O)=O |r|
PDB

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n/an/an/an/a 5.00E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50583028
PNG
(CHEMBL5087550)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1cccc(c1)C(F)(F)F)C(O)=O |r|
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n/an/an/an/a 7.70E+3n/an/an/an/a


TBA

Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2D


(RAT-Rattus norvegicus (Rat))
BDBM50583030
PNG
(CHEMBL5083882)
Show SMILES N[C@H](CNC(=O)c1ccc(o1)-c1ccc(Cl)c(Cl)c1)C(O)=O |r|
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n/an/an/an/a 3.10E+4n/an/an/an/a


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Assay Description
Agonist activity at rat GluN1/GluN2D NMDA receptor expressed in Xenopus oocytes measured after 4 days in presence of L-glutamte by two-electrode volt...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01810
BindingDB Entry DOI: 10.7270/Q21R6VFZ
More data for this
Ligand-Target Pair
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