Compile Data Set for Download or QSAR

Found 36 hits with Last Name = 'czerwi?ska' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508585 (CHEMBL4550810) Show SMILES Nc1c(sc(NCCN2CCNCC2)c1C#N)C(=O)c1ccc(Br)s1 Show InChI InChI=1S/C16H18BrN5OS2/c17-12-2-1-11(24-12)14(23)15-13(19)10(9-18)16(25-15)21-5-8-22-6-3-20-4-7-22/h1-2,20-21H,3-8,19H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508596 (CHEMBL4450084) Show SMILES CC(C)Nc1sc(C(=O)c2ccc(I)s2)c(N)c1C#N Show InChI InChI=1S/C13H12IN3OS2/c1-6(2)17-13-7(5-15)10(16)12(20-13)11(18)8-3-4-9(14)19-8/h3-4,6,17H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508606 (CHEMBL4452507) Show SMILES CC(C)Nc1sc(C(=O)c2ccc(Br)s2)c(N)c1C#N Show InChI InChI=1S/C13H12BrN3OS2/c1-6(2)17-13-7(5-15)10(16)12(20-13)11(18)8-3-4-9(14)19-8/h3-4,6,17H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508586 (CHEMBL4543318) Show SMILES NCCCNc1sc(C(=O)c2ccc(Br)s2)c(N)c1C#N Show InChI InChI=1S/C13H13BrN4OS2/c14-9-3-2-8(20-9)11(19)12-10(17)7(6-16)13(21-12)18-5-1-4-15/h2-3,18H,1,4-5,15,17H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508584 (CHEMBL4563315) Show SMILES CC(C)Nc1sc(C(=O)c2ccc(Cl)s2)c(N)c1C#N Show InChI InChI=1S/C13H12ClN3OS2/c1-6(2)17-13-7(5-15)10(16)12(20-13)11(18)8-3-4-9(14)19-8/h3-4,6,17H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508602 (CHEMBL4451160) Show SMILES CCNc1sc(C(=O)c2ccc(Cl)s2)c(N)c1C#N Show InChI InChI=1S/C12H10ClN3OS2/c1-2-16-12-6(5-14)9(15)11(19-12)10(17)7-3-4-8(13)18-7/h3-4,16H,2,15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508593 (CHEMBL4471276) Show SMILES CC(C)Nc1sc(C(=O)c2ccc(s2)-c2ccc(O)cc2)c(N)c1C#N Show InChI InChI=1S/C19H17N3O2S2/c1-10(2)22-19-13(9-20)16(21)18(26-19)17(24)15-8-7-14(25-15)11-3-5-12(23)6-4-11/h3-8,10,22-23H,21H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	241	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508594 (CHEMBL4525991) Show SMILES CC(C)Nc1sc(C(=O)c2ccc(s2)-c2ccncc2)c(N)c1C#N Show InChI InChI=1S/C18H16N4OS2/c1-10(2)22-18-12(9-19)15(20)17(25-18)16(23)14-4-3-13(24-14)11-5-7-21-8-6-11/h3-8,10,22H,20H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	269	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508610 (CHEMBL4561737) Show SMILES Nc1c(sc(NCCO)c1C#N)C(=O)c1ccc(Br)s1 Show InChI InChI=1S/C12H10BrN3O2S2/c13-8-2-1-7(19-8)10(18)11-9(15)6(5-14)12(20-11)16-3-4-17/h1-2,16-17H,3-4,15H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	313	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508592 (CHEMBL4535071) Show SMILES CC(C)Nc1sc(C(=O)c2ccc(s2)-c2cccc(O)c2)c(N)c1C#N Show InChI InChI=1S/C19H17N3O2S2/c1-10(2)22-19-13(9-20)16(21)18(26-19)17(24)15-7-6-14(25-15)11-4-3-5-12(23)8-11/h3-8,10,22-23H,21H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508603 (CHEMBL4525206) Show SMILES CC(C)Nc1sc(C(=O)c2ccc(Cl)s2)c(N)c1C(N)=O Show InChI InChI=1S/C13H14ClN3O2S2/c1-5(2)17-13-8(12(16)19)9(15)11(21-13)10(18)6-3-4-7(14)20-6/h3-5,17H,15H2,1-2H3,(H2,16,19)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	388	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508595 (CHEMBL4584382) Show SMILES CC(C)Nc1sc(C(=O)c2ccc(C)s2)c(N)c1C#N Show InChI InChI=1S/C14H15N3OS2/c1-7(2)17-14-9(6-15)11(16)13(20-14)12(18)10-5-4-8(3)19-10/h4-5,7,17H,16H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	494	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508601 (CHEMBL4476804) Show SMILES NC(=O)CNc1sc(C(=O)c2ccc(Br)s2)c(N)c1C#N Show InChI InChI=1S/C12H9BrN4O2S2/c13-7-2-1-6(20-7)10(19)11-9(16)5(3-14)12(21-11)17-4-8(15)18/h1-2,17H,4,16H2,(H2,15,18)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508604 (CHEMBL4538177) Show SMILES CC(C)Nc1sc(C(=O)c2cc(Cl)cs2)c(N)c1C#N Show InChI InChI=1S/C13H12ClN3OS2/c1-6(2)17-13-8(4-15)10(16)12(20-13)11(18)9-3-7(14)5-19-9/h3,5-6,17H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	575	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508612 (CHEMBL4454199) Show SMILES CC(C)Nc1sc(C(=O)c2cc(Br)cs2)c(N)c1C#N Show InChI InChI=1S/C13H12BrN3OS2/c1-6(2)17-13-8(4-15)10(16)12(20-13)11(18)9-3-7(14)5-19-9/h3,5-6,17H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	599	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508589 (CHEMBL4466246) Show SMILES Nc1c(sc(NCC=C)c1C#N)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C13H10ClN3OS2/c1-2-5-17-13-7(6-15)10(16)12(20-13)11(18)8-3-4-9(14)19-8/h2-4,17H,1,5,16H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	638	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508587 (CHEMBL4517341) Show SMILES Nc1c(sc(Nc2ccccc2F)c1C#N)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C16H9ClFN3OS2/c17-12-6-5-11(23-12)14(22)15-13(20)8(7-19)16(24-15)21-10-4-2-1-3-9(10)18/h1-6,21H,20H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	707	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508600 (CHEMBL4579783) Show SMILES CC(C)Nc1sc(C(=O)c2ccc3OCOc3c2)c(N)c1C#N Show InChI InChI=1S/C16H15N3O3S/c1-8(2)19-16-10(6-17)13(18)15(23-16)14(20)9-3-4-11-12(5-9)22-7-21-11/h3-5,8,19H,7,18H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508609 (CHEMBL1419805) Show SMILES CCNc1sc(C(=O)c2cccs2)c(N)c1C#N Show InChI InChI=1S/C12H11N3OS2/c1-2-15-12-7(6-13)9(14)11(18-12)10(16)8-4-3-5-17-8/h3-5,15H,2,14H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508613 (CHEMBL4564918) Show SMILES CC(C)Nc1sc(C(=O)c2ccco2)c(N)c1C#N Show InChI InChI=1S/C13H13N3O2S/c1-7(2)16-13-8(6-14)10(15)12(19-13)11(17)9-4-3-5-18-9/h3-5,7,16H,15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508614 (CHEMBL4577252) Show SMILES CC(C)N(C)c1sc(C(=O)c2ccc(Cl)s2)c(N)c1C#N Show InChI InChI=1S/C14H14ClN3OS2/c1-7(2)18(3)14-8(6-16)11(17)13(21-14)12(19)9-4-5-10(15)20-9/h4-5,7H,17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508605 (CHEMBL4467842) Show SMILES CC(C)Nc1sc(C(=O)c2ccn[nH]2)c(N)c1C#N Show InChI InChI=1S/C12H13N5OS/c1-6(2)16-12-7(5-13)9(14)11(19-12)10(18)8-3-4-15-17-8/h3-4,6,16H,14H2,1-2H3,(H,15,17)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508608 (CHEMBL4461952) Show SMILES COc1ccc(cc1OC)C(=O)c1sc(NC(C)C)c(C#N)c1N Show InChI InChI=1S/C17H19N3O3S/c1-9(2)20-17-11(8-18)14(19)16(24-17)15(21)10-5-6-12(22-3)13(7-10)23-4/h5-7,9,20H,19H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508599 (CHEMBL4445131) Show SMILES COc1ccc(cc1)C(=O)c1sc(NC(C)C)c(C#N)c1N Show InChI InChI=1S/C16H17N3O2S/c1-9(2)19-16-12(8-17)13(18)15(22-16)14(20)10-4-6-11(21-3)7-5-10/h4-7,9,19H,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508611 (CHEMBL3975306) Show SMILES Cc1ccc(cc1)C(=O)c1sc2nc(C)ccc2c1N Show InChI InChI=1S/C16H14N2OS/c1-9-3-6-11(7-4-9)14(19)15-13(17)12-8-5-10(2)18-16(12)20-15/h3-8H,17H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508607 (CHEMBL4563640) Show SMILES CC(C)Nc1sc(C(=O)c2cccc(c2)C#N)c(N)c1C#N Show InChI InChI=1S/C16H14N4OS/c1-9(2)20-16-12(8-18)13(19)15(22-16)14(21)11-5-3-4-10(6-11)7-17/h3-6,9,20H,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM49075 (2-(allylamino)-4-amino-5-(2,2-dimethylpropanoyl)-3...) Show SMILES CC(C)(C)C(=O)c1sc(NCC=C)c(C#N)c1N Show InChI InChI=1S/C13H17N3OS/c1-5-6-16-12-8(7-14)9(15)10(18-12)11(17)13(2,3)4/h5,16H,1,6,15H2,2-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508598 (CHEMBL4446294) Show SMILES CC(C)Nc1sc(C(=O)c2ccncc2)c(N)c1C#N Show InChI InChI=1S/C14H14N4OS/c1-8(2)18-14-10(7-15)11(16)13(20-14)12(19)9-3-5-17-6-4-9/h3-6,8,18H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508597 (CHEMBL4560455) Show SMILES CC(C)Nc1sc(C(=O)c2cccnc2)c(N)c1C#N Show InChI InChI=1S/C14H14N4OS/c1-8(2)18-14-10(6-15)11(16)13(20-14)12(19)9-4-3-5-17-7-9/h3-5,7-8,18H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508591 (CHEMBL4460795) Show SMILES CC(C)Nc1nc(N)c(s1)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C11H12ClN3OS2/c1-5(2)14-11-15-10(13)9(18-11)8(16)6-3-4-7(12)17-6/h3-5H,13H2,1-2H3,(H,14,15)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508590 (CHEMBL4585980) Show SMILES COc1ccc(cc1OC)C(=O)c1sc2nc(C)ccc2c1N Show InChI InChI=1S/C17H16N2O3S/c1-9-4-6-11-14(18)16(23-17(11)19-9)15(20)10-5-7-12(21-2)13(8-10)22-3/h4-8H,18H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508588 (CHEMBL4471795) Show SMILES Nc1c(sc(NCc2ccccc2)c1C#N)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C17H12ClN3OS2/c18-13-7-6-12(23-13)15(22)16-14(20)11(8-19)17(24-16)21-9-10-4-2-1-3-5-10/h1-7,21H,9,20H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508583 (CHEMBL4466827) Show SMILES CC(C)Nc1sc(C(C)=O)c(N)c1C#N Show InChI InChI=1S/C10H13N3OS/c1-5(2)13-10-7(4-11)8(12)9(15-10)6(3)14/h5,13H,12H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508615 (CHEMBL4549181) Show SMILES CC(C)Nc1sc(C(=O)c2ccc(cc2)C#N)c(N)c1C#N Show InChI InChI=1S/C16H14N4OS/c1-9(2)20-16-12(8-18)13(19)15(22-16)14(21)11-5-3-10(7-17)4-6-11/h3-6,9,20H,19H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508581 (CHEMBL4544167) Show SMILES Nc1c(sc(Nc2ccccc2C#N)c1C#N)C(=O)c1ccc(Br)s1 Show InChI InChI=1S/C17H9BrN4OS2/c18-13-6-5-12(24-13)15(23)16-14(21)10(8-20)17(25-16)22-11-4-2-1-3-9(11)7-19/h1-6,22H,21H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508582 (CHEMBL4468259) Show SMILES CC(C)Nc1sc(cc1C#N)C(=O)c1ccc(Cl)s1 Show InChI InChI=1S/C13H11ClN2OS2/c1-7(2)16-13-8(6-15)5-10(19-13)12(17)9-3-4-11(14)18-9/h3-5,7,16H,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051 BindingDB Entry DOI: 10.7270/Q2377D0K
					More data for this Ligand-Target Pair