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Compile Data Set for Download or QSAR

Found 31 hits with Last Name = 'd''amour' and Initial = 'k'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50078044
PNG
(3-(6-Chloro-pyridin-3-ylmethyl)-3H-thiazol-(2E)-yl...)
Show SMILES Clc1ccc(Cn2ccsc2=N)cn1
Show InChI InChI=1S/C9H8ClN3S/c10-8-2-1-7(5-12-8)6-13-3-4-14-9(13)11/h1-5,11H,6H2
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n/an/a 0.910n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50078056
PNG
(2-Chloro-5-(1-methyl-pyrrolidin-2-yl)-pyridine | C...)
Show SMILES CN1CCCC1c1ccc(Cl)nc1
Show InChI InChI=1S/C10H13ClN2/c1-13-6-2-3-9(13)8-4-5-10(11)12-7-8/h4-5,7,9H,2-3,6H2,1H3
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n/an/a 1.90n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472282
PNG
(descyanothiacloprid)
Show SMILES Clc1ccc(CN2CCSC2=N)cn1
Show InChI InChI=1S/C9H10ClN3S/c10-8-2-1-7(5-12-8)6-13-3-4-14-9(13)11/h1-2,5,11H,3-4,6H2
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n/an/a 2.30n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472297
PNG
(CHEMBL308637)
Show SMILES NC1=NCCCCN1Cc1ccc(Cl)nc1 |t:1|
Show InChI InChI=1S/C11H15ClN4/c12-10-4-3-9(7-15-10)8-16-6-2-1-5-14-11(16)13/h3-4,7H,1-2,5-6,8H2,(H2,13,14)
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n/an/a 2.80n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472290
PNG
(CHEMBL440307)
Show SMILES Clc1ccc(CN2CCCC2=N)cn1
Show InChI InChI=1S/C10H12ClN3/c11-9-4-3-8(6-13-9)7-14-5-1-2-10(14)12/h3-4,6,12H,1-2,5,7H2
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n/an/a 3.5n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM82070
PNG
(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Show SMILES CN1CCC[C@H]1c1cccnc1 |r|
Show InChI InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
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n/an/a 3.80n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50078048
PNG
(1-(6-Chloro-pyridin-3-ylmethyl)-imidazolidin-(2Z)-...)
Show SMILES NC1=NCCN1Cc1ccc(Cl)nc1 |t:1|
Show InChI InChI=1S/C9H11ClN4/c10-8-2-1-7(5-13-8)6-14-4-3-12-9(14)11/h1-2,5H,3-4,6H2,(H2,11,12)
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n/an/a 6n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472292
PNG
(CHEMBL309577)
Show SMILES Clc1ccc(CN2CCOC2=N)cn1
Show InChI InChI=1S/C9H10ClN3O/c10-8-2-1-7(5-12-8)6-13-3-4-14-9(13)11/h1-2,5,11H,3-4,6H2
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n/an/a 7.20n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472295
PNG
(CHEMBL431574)
Show SMILES Clc1ccc(CN2CCCC2)cn1
Show InChI InChI=1S/C10H13ClN2/c11-10-4-3-9(7-12-10)8-13-5-1-2-6-13/h3-4,7H,1-2,5-6,8H2
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n/an/a 8.80n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472285
PNG
(CHEMBL72334)
Show SMILES Clc1ccc(CN2CCCCC2=N)cn1
Show InChI InChI=1S/C11H14ClN3/c12-10-5-4-9(7-14-10)8-15-6-2-1-3-11(15)13/h4-5,7,13H,1-3,6,8H2
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n/an/a 11n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472280
PNG
(CHEMBL307036)
Show SMILES Clc1ccc(CN2CCCSC2=N)cn1
Show InChI InChI=1S/C10H12ClN3S/c11-9-3-2-8(6-13-9)7-14-4-1-5-15-10(14)12/h2-3,6,12H,1,4-5,7H2
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n/an/a 14n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50246829
PNG
(CHEMBL70624)
Show SMILES NC1=NCCN1Cc1cccnc1 |t:1|
Show InChI InChI=1S/C9H12N4/c10-9-12-4-5-13(9)7-8-2-1-3-11-6-8/h1-3,6H,4-5,7H2,(H2,10,12)
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n/an/a 14n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472289
PNG
(CHEMBL72201)
Show SMILES Clc1ccc(CN2CCCCC2)cn1
Show InChI InChI=1S/C11H15ClN2/c12-11-5-4-10(8-13-11)9-14-6-2-1-3-7-14/h4-5,8H,1-3,6-7,9H2
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n/an/a 14n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472293
PNG
(CHEMBL71583)
Show SMILES C[N+](C)(C)Cc1ccc(Cl)nc1
Show InChI InChI=1S/C9H14ClN2/c1-12(2,3)7-8-4-5-9(10)11-6-8/h4-6H,7H2,1-3H3/q+1
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n/an/a 16n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 1


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472283
PNG
(CHEMBL304517)
Show SMILES Clc1ccc(CN2CCC2)cn1
Show InChI InChI=1S/C9H11ClN2/c10-9-3-2-8(6-11-9)7-12-4-1-5-12/h2-3,6H,1,4-5,7H2
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n/an/a 16n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472293
PNG
(CHEMBL71583)
Show SMILES C[N+](C)(C)Cc1ccc(Cl)nc1
Show InChI InChI=1S/C9H14ClN2/c1-12(2,3)7-8-4-5-9(10)11-6-8/h4-6H,7H2,1-3H3/q+1
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n/an/a 20n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 2


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472288
PNG
(CHEMBL73345)
Show SMILES Nc1nccn1Cc1ccc(Cl)nc1
Show InChI InChI=1S/C9H9ClN4/c10-8-2-1-7(5-13-8)6-14-4-3-12-9(14)11/h1-5H,6H2,(H2,11,12)
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n/an/a 23n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472296
PNG
(CHEMBL73887)
Show SMILES NC1=NCCCN1Cc1ccc(Cl)nc1 |t:1|
Show InChI InChI=1S/C10H13ClN4/c11-9-3-2-8(6-14-9)7-15-5-1-4-13-10(15)12/h2-3,6H,1,4-5,7H2,(H2,12,13)
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n/an/a 63n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472298
PNG
(CHEMBL306188)
Show SMILES Clc1ccc(Cn2ccnc2)cn1
Show InChI InChI=1S/C9H8ClN3/c10-9-2-1-8(5-12-9)6-13-4-3-11-7-13/h1-5,7H,6H2
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n/an/a 450n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472287
PNG
(CHEMBL309136)
Show SMILES Clc1ccc(CN2CCN(Cc3ccc(Cl)nc3)CC2)cn1
Show InChI InChI=1S/C16H18Cl2N4/c17-15-3-1-13(9-19-15)11-21-5-7-22(8-6-21)12-14-2-4-16(18)20-10-14/h1-4,9-10H,5-8,11-12H2
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n/an/a 1.65E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 2


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472287
PNG
(CHEMBL309136)
Show SMILES Clc1ccc(CN2CCN(Cc3ccc(Cl)nc3)CC2)cn1
Show InChI InChI=1S/C16H18Cl2N4/c17-15-3-1-13(9-19-15)11-21-5-7-22(8-6-21)12-14-2-4-16(18)20-10-14/h1-4,9-10H,5-8,11-12H2
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n/an/a 1.74E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 1


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472281
PNG
(CHEMBL539622)
Show SMILES [Cl-].CC[N+](CC)(CC)Cc1ccc(Cl)nc1
Show InChI InChI=1S/C12H20ClN2/c1-4-15(5-2,6-3)10-11-7-8-12(13)14-9-11/h7-9H,4-6,10H2,1-3H3/q+1
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n/an/a 2.40E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 2


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472286
PNG
(CHEMBL71112)
Show SMILES CN1CCCC1c1cccnc1Cl
Show InChI InChI=1S/C10H13ClN2/c1-13-7-3-5-9(13)8-4-2-6-12-10(8)11/h2,4,6,9H,3,5,7H2,1H3
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n/an/a 3.20E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472284
PNG
(CHEMBL72542)
Show SMILES CCN(Cc1ccc(Cl)nc1)C(=N)NC
Show InChI InChI=1S/C10H15ClN4/c1-3-15(10(12)13-2)7-8-4-5-9(11)14-6-8/h4-6H,3,7H2,1-2H3,(H2,12,13)
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UniChem
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PubMed
n/an/a 3.30E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472281
PNG
(CHEMBL539622)
Show SMILES [Cl-].CC[N+](CC)(CC)Cc1ccc(Cl)nc1
Show InChI InChI=1S/C12H20ClN2/c1-4-15(5-2,6-3)10-11-7-8-12(13)14-9-11/h7-9H,4-6,10H2,1-3H3/q+1
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n/an/a 3.70E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 1


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472294
PNG
(CHEBI:83544 | CHEMBL71188)
Show SMILES Clc1ccc(CN2CCNC2=O)cn1
Show InChI InChI=1S/C9H10ClN3O/c10-8-2-1-7(5-12-8)6-13-4-3-11-9(13)14/h1-2,5H,3-4,6H2,(H,11,14)
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n/an/a 8.10E+3n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472291
PNG
(CHEMBL431760)
Show SMILES SC1=NCCN1Cc1ccc(Cl)nc1 |t:1|
Show InChI InChI=1S/C9H10ClN3S/c10-8-2-1-7(5-12-8)6-13-4-3-11-9(13)14/h1-2,5H,3-4,6H2,(H,11,14)
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n/an/a 1.26E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 1


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50472291
PNG
(CHEMBL431760)
Show SMILES SC1=NCCN1Cc1ccc(Cl)nc1 |t:1|
Show InChI InChI=1S/C9H10ClN3S/c10-8-2-1-7(5-12-8)6-13-4-3-11-9(13)14/h1-2,5H,3-4,6H2,(H,11,14)
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n/an/a 1.35E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 2


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50078037
PNG
(CHEMBL69446 | Oxazolidin-(2Z)-ylideneamine)
Show SMILES NC1=NCCO1 |t:1|
Show InChI InChI=1S/C3H6N2O/c4-3-5-1-2-6-3/h1-2H2,(H2,4,5)
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PubMed
n/an/a 9.53E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 2


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50078037
PNG
(CHEMBL69446 | Oxazolidin-(2Z)-ylideneamine)
Show SMILES NC1=NCCO1 |t:1|
Show InChI InChI=1S/C3H6N2O/c4-3-5-1-2-6-3/h1-2H2,(H2,4,5)
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n/an/a 9.95E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR was determined; experiment 1


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2


(Rattus norvegicus (Rat))
BDBM50049250
PNG
(CHEMBL306541 | [1,3]Thiazinan-(2E)-ylideneamine | ...)
Show SMILES NC1=NCCCS1 |t:1|
Show InChI InChI=1S/C4H8N2S/c5-4-6-2-1-3-7-4/h1-3H2,(H2,5,6)
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n/an/a 1.60E+5n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-nicotine binding to recombinant rat alpha4-beta2 nAChR.


J Med Chem 42: 2227-34 (1999)


Article DOI: 10.1021/jm980721x
BindingDB Entry DOI: 10.7270/Q23X89CJ
More data for this
Ligand-Target Pair