Compile Data Set for Download or QSAR

Found 30 hits with Last Name = 'diaz' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506009 (CHEMBL4476197) Show SMILES Cc1ccc(cc1C(N)=O)C#CCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C25H30N8O6/c1-13-4-5-14(9-15(13)22(28)36)3-2-7-32(8-6-16(26)25(37)38)10-17-19(34)20(35)24(39-17)33-12-31-18-21(27)29-11-30-23(18)33/h4-5,9,11-12,16-17,19-20,24,34-35H,6-8,10,26H2,1H3,(H2,28,36)(H,37,38)(H2,27,29,30)/t16-,17+,19+,20+,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506011 (CHEMBL4436698) Show SMILES N[C@@H](CCN(CCCc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H32N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,2,4,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506015 (CHEMBL4556842) Show SMILES Cc1ccc(CCCN(CC[C@H](N)C(O)=O)C[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)cc1C(N)=O |r| Show InChI InChI=1S/C25H34N8O6/c1-13-4-5-14(9-15(13)22(28)36)3-2-7-32(8-6-16(26)25(37)38)10-17-19(34)20(35)24(39-17)33-12-31-18-21(27)29-11-30-23(18)33/h4-5,9,11-12,16-17,19-20,24,34-35H,2-3,6-8,10,26H2,1H3,(H2,28,36)(H,37,38)(H2,27,29,30)/t16-,17+,19+,20+,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506008 (CHEMBL4439305) Show SMILES COc1ccc(cc1C#CCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(N)=O |r| Show InChI InChI=1S/C25H30N8O7/c1-39-16-5-4-14(22(28)36)9-13(16)3-2-7-32(8-6-15(26)25(37)38)10-17-19(34)20(35)24(40-17)33-12-31-18-21(27)29-11-30-23(18)33/h4-5,9,11-12,15,17,19-20,24,34-35H,6-8,10,26H2,1H3,(H2,28,36)(H,37,38)(H2,27,29,30)/t15-,17+,19+,20+,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506003 (CHEMBL4522203) Show SMILES Cc1ccc(cc1CCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(N)=O |r| Show InChI InChI=1S/C25H34N8O6/c1-13-4-5-15(22(28)36)9-14(13)3-2-7-32(8-6-16(26)25(37)38)10-17-19(34)20(35)24(39-17)33-12-31-18-21(27)29-11-30-23(18)33/h4-5,9,11-12,16-17,19-20,24,34-35H,2-3,6-8,10,26H2,1H3,(H2,28,36)(H,37,38)(H2,27,29,30)/t16-,17+,19+,20+,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506002 (CHEMBL4437502) Show SMILES N[C@@H](CCCN(CCCCc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C26H36N8O6/c27-17(26(38)39)8-4-10-33(9-2-1-5-15-6-3-7-16(11-15)23(29)37)12-18-20(35)21(36)25(40-18)34-14-32-19-22(28)30-13-31-24(19)34/h3,6-7,11,13-14,17-18,20-21,25,35-36H,1-2,4-5,8-10,12,27H2,(H2,29,37)(H,38,39)(H2,28,30,31)/t17-,18+,20+,21+,25+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506013 (CHEMBL4557645) Show SMILES N[C@@H](CCN(CCCCc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C25H34N8O6/c26-16(25(37)38)7-9-32(8-2-1-4-14-5-3-6-15(10-14)22(28)36)11-17-19(34)20(35)24(39-17)33-13-31-18-21(27)29-12-30-23(18)33/h3,5-6,10,12-13,16-17,19-20,24,34-35H,1-2,4,7-9,11,26H2,(H2,28,36)(H,37,38)(H2,27,29,30)/t16-,17+,19+,20+,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	840	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506005 (CHEMBL4517536) Show SMILES N[C@@H](CCCN(CCCc1cccc2ccccc12)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C28H35N7O5/c29-20(28(38)39)11-5-13-34(12-4-9-18-8-3-7-17-6-1-2-10-19(17)18)14-21-23(36)24(37)27(40-21)35-16-33-22-25(30)31-15-32-26(22)35/h1-3,6-8,10,15-16,20-21,23-24,27,36-37H,4-5,9,11-14,29H2,(H,38,39)(H2,30,31,32)/t20-,21+,23+,24+,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506004 (CHEMBL4542138) Show SMILES N[C@@H](CCCN(CCCc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C25H34N8O6/c26-16(25(37)38)7-3-9-32(8-2-5-14-4-1-6-15(10-14)22(28)36)11-17-19(34)20(35)24(39-17)33-13-31-18-21(27)29-12-30-23(18)33/h1,4,6,10,12-13,16-17,19-20,24,34-35H,2-3,5,7-9,11,26H2,(H2,28,36)(H,37,38)(H2,27,29,30)/t16-,17+,19+,20+,24+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506010 (CHEMBL4467665) Show SMILES NC(=O)c1cccc(c1)C#CCNC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C20H21N7O4/c21-17-14-19(25-9-24-17)27(10-26-14)20-16(29)15(28)13(31-20)8-23-6-2-4-11-3-1-5-12(7-11)18(22)30/h1,3,5,7,9-10,13,15-16,20,23,28-29H,6,8H2,(H2,22,30)(H2,21,24,25)/t13-,15-,16-,20-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506006 (CHEMBL4454317) Show SMILES N[C@@H](CCN(CCCc1ccc2ccccc2c1)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C27H33N7O5/c28-19(27(37)38)9-11-33(10-3-4-16-7-8-17-5-1-2-6-18(17)12-16)13-20-22(35)23(36)26(39-20)34-15-32-21-24(29)30-14-31-25(21)34/h1-2,5-8,12,14-15,19-20,22-23,26,35-36H,3-4,9-11,13,28H2,(H,37,38)(H2,29,30,31)/t19-,20+,22+,23+,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50247635 (CHEMBL4100002) Show SMILES N[C@@H](CCN(CCc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C23H30N8O6/c24-14(23(35)36)5-7-30(6-4-12-2-1-3-13(8-12)20(26)34)9-15-17(32)18(33)22(37-15)31-11-29-16-19(25)27-10-28-21(16)31/h1-3,8,10-11,14-15,17-18,22,32-33H,4-7,9,24H2,(H2,26,34)(H,35,36)(H2,25,27,28)/t14-,15+,17+,18+,22+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506001 (CHEMBL4581026) Show SMILES N[C@@H](CCN(CCCc1cccc2ccccc12)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C27H33N7O5/c28-19(27(37)38)10-12-33(11-4-8-17-7-3-6-16-5-1-2-9-18(16)17)13-20-22(35)23(36)26(39-20)34-15-32-21-24(29)30-14-31-25(21)34/h1-3,5-7,9,14-15,19-20,22-23,26,35-36H,4,8,10-13,28H2,(H,37,38)(H2,29,30,31)/t19-,20+,22+,23+,26+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506014 (CHEMBL4458772) Show SMILES N[C@@H](CCN(CCc1ccc2ccccc2c1)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C26H31N7O5/c27-18(26(36)37)8-10-32(9-7-15-5-6-16-3-1-2-4-17(16)11-15)12-19-21(34)22(35)25(38-19)33-14-31-20-23(28)29-13-30-24(20)33/h1-6,11,13-14,18-19,21-22,25,34-35H,7-10,12,27H2,(H,36,37)(H2,28,29,30)/t18-,19+,21+,22+,25+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.73E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506007 (CHEMBL4572902) Show SMILES COC(=O)c1cccc(CCCN(CC[C@H](N)C(O)=O)C[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)c1 |r| Show InChI InChI=1S/C25H33N7O7/c1-38-25(37)15-6-2-4-14(10-15)5-3-8-31(9-7-16(26)24(35)36)11-17-19(33)20(34)23(39-17)32-13-30-18-21(27)28-12-29-22(18)32/h2,4,6,10,12-13,16-17,19-20,23,33-34H,3,5,7-9,11,26H2,1H3,(H,35,36)(H2,27,28,29)/t16-,17+,19+,20+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50506012 (CHEMBL4561228) Show SMILES N[C@@H](CCCN(CCCc1ccc2ccccc2c1)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C28H35N7O5/c29-20(28(38)39)8-4-12-34(11-3-5-17-9-10-18-6-1-2-7-19(18)13-17)14-21-23(36)24(37)27(40-21)35-16-33-22-25(30)31-15-32-26(22)35/h1-2,6-7,9-10,13,15-16,20-21,23-24,27,36-37H,3-5,8,11-12,14,29H2,(H,38,39)(H2,30,31,32)/t20-,21+,23+,24+,27+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.33E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50106187 (Benzenecarboxamide | Benzoic acid amide | Benzoyla...) Show SMILES NC(=O)c1ccccc1 Show InChI InChI=1S/C7H7NO/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H2,8,9)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of full-length human N-terminal TEV cleavage site NNMT (1 to 270 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIPL cells us...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Nicotinamide N-methyltransferase (Homo sapiens (Human))	BDBM50455084 (CHEMBL4214098) Show SMILES COc1ccc(C(N)=O)c(C)n1 Show InChI InChI=1S/C8H10N2O2/c1-5-6(8(9)11)3-4-7(10-5)12-2/h3-4H,1-2H3,(H2,9,11)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human NNMT using nicotinamide as substrate preincubated for 30 mins followed by substrate addition in presence of AdoMet and measured a...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Adenosylhomocysteinase (Homo sapiens (Human))	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of SAHH (unknown origin) using SAH as substrate preincubated for 10 mins followed by susbtrate addition by fluorescence based assay				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of NTMT1 (unknown origin) using GPKRIA peptide as substrate preincubated for 10 mins in presence of AdoMet followed by susbtrate addition ...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EHMT2 (Homo sapiens (Human))	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human G9a (913 to 1193 residues) expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using H3-21 peptide preincubated for...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Indolethylamine N-methyltransferase (Homo sapiens (Human))	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human N- terminal His6 tagged human INMT expressed in Escherichia coli BL21-CodonPlus(DE3)-RIL using tryptamine as substrate preincubat...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Rattus norvegicus)	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant rat His-tagged PRMT1 expressed in Escherichia coli BL21(DE3) cells using H4-21 peptide as susbtrate preincubated for 10 min...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase SETD7 (Homo sapiens (Human))	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged SETD7 (1 to 366 residues) expressed in Escherichia coli using H3-21 peptide as susbtrate preincubated for ...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Homo sapiens (Human))	BDBM50506000 (CHEMBL4445337) Show SMILES N[C@@H](CCN(CC#Cc1cccc(c1)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C24H28N8O6/c25-15(24(36)37)6-8-31(7-2-4-13-3-1-5-14(9-13)21(27)35)10-16-18(33)19(34)23(38-16)32-12-30-17-20(26)28-11-29-22(17)32/h1,3,5,9,11-12,15-16,18-19,23,33-34H,6-8,10,25H2,(H2,27,35)(H,36,37)(H2,26,28,29)/t15-,16+,18+,19+,23+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human N-terminal His6 tagged PNMT using norepinephrine as substrate preincubated for 10 mins in presence of AdoMet followed by substrat...				J Med Chem 62: 10783-10797 (2019) Article DOI: 10.1021/acs.jmedchem.9b01255 BindingDB Entry DOI: 10.7270/Q2WD43VS
					More data for this Ligand-Target Pair