Found 81 hits with Last Name = 'hinnah' and Initial = 'k' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546858
(CHEMBL4743099)Show SMILES Cc1ccccc1-c1ccc(cc1)\N=N/c1ccc(CC2SC(=O)NC2=O)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARy in human HepG2 cells transfected with human PPRE incubated for 14 to 16 hrs using pre-irradiated compound by firefly lucife... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546858
(CHEMBL4743099)Show SMILES Cc1ccccc1-c1ccc(cc1)\N=N/c1ccc(CC2SC(=O)NC2=O)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to recombinant PPARy LBD (unknown origin) expressed in Escherichia coli BL21 DE3 using pre-irradiated compound by ITC assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546859
(CHEMBL4787702)Show SMILES OC(=O)[C@H](Cc1ccc(cc1)\N=N\c1ccccc1)Nc1ccccc1C(=O)c1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546860
(CHEMBL4762401) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546861
(CHEMBL4755265)Show SMILES OC(=O)[C@H](Cc1ccc(cc1)\N=N\c1ccc(Cl)cc1)Nc1ccccc1C(=O)c1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546862
(CHEMBL4745294) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546863
(CHEMBL4751747)Show SMILES FC(F)(F)c1ccc(cc1)\N=N\c1ccc(CC2SC(=O)NC2=O)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546864
(CHEMBL4742137)Show SMILES Cc1ccccc1-c1ccc(cc1)\N=N\c1ccc(CC2SC(=O)NC2=O)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546858
(CHEMBL4743099)Show SMILES Cc1ccccc1-c1ccc(cc1)\N=N/c1ccc(CC2SC(=O)NC2=O)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 6.40E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546865
(CHEMBL4792723)Show SMILES OC(=O)[C@H](Cc1ccc(cc1)\N=N/c1ccccc1)Nc1ccccc1C(=O)c1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546866
(CHEMBL4784654)Show SMILES OC(=O)[C@H](Cc1ccc(cc1)\N=N/c1ccc(Cl)cc1)Nc1ccccc1C(=O)c1ccccc1 |r| | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546867
(CHEMBL4756972) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546868
(CHEMBL4799629) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50546869
(CHEMBL4792982)Show SMILES FC(F)(F)c1ccc(cc1)\N=N/c1ccc(CC2SC(=O)NC2=O)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) expressed in HEK293T cells incubated for 14 to 16 hrs under irradiation by hybrid Gal4 reporter gene a... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50085048
((S)-2-(2-Benzoyl-phenylamino)-3-{4-[2-(methyl-pyri...)Show SMILES CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c2ccccc2)C(O)=O)cc1)c1ccccn1 Show InChI InChI=1S/C30H29N3O4/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23/h2-18,27,32H,19-21H2,1H3,(H,35,36)/t27-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at PPARgamma (unknown origin) |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00654 BindingDB Entry DOI: 10.7270/Q2154MN4 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50401993
(CHEMBL2204696)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C24H24N2O4/c1-24(2,23(27)28)30-22-12-8-18(9-13-22)16-17-29-21-14-10-20(11-15-21)26-25-19-6-4-3-5-7-19/h3-15H,16-17H2,1-2H3,(H,27,28)/b26-25+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580792
(CHEMBL5087457)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N/c2ccccc2)cc1)C(O)=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50401994
(CHEMBL2204695)Show SMILES CC(C)(Oc1ccc(COc2ccc(cc2)\N=N\c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C23H22N2O4/c1-23(2,22(26)27)29-21-12-8-17(9-13-21)16-28-20-14-10-19(11-15-20)25-24-18-6-4-3-5-7-18/h3-15H,16H2,1-2H3,(H,26,27)/b25-24+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580793
(CHEMBL5079941)Show SMILES CC(C)(Oc1ccc(COc2ccc(cc2)\N=N/c2ccccc2)cc1)C(O)=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580794
(CHEMBL5090949)Show SMILES Cc1ccc(cc1)\N=N\c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)cc1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580795
(CHEMBL5075561)Show SMILES Cc1ccc(cc1)\N=N/c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)cc1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50535438
(CHEMBL4471853)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C24H23ClN2O4/c1-24(2,23(28)29)31-22-11-3-17(4-12-22)15-16-30-21-13-9-20(10-14-21)27-26-19-7-5-18(25)6-8-19/h3-14H,15-16H2,1-2H3,(H,28,29)/b27-26+ | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580796
(CHEMBL5078286)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N/c2ccc(Cl)cc2)cc1)C(O)=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580797
(CHEMBL5085675)Show SMILES CC(C)c1ccc(cc1)\N=N\c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)cc1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.77E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580798
(CHEMBL5093865)Show SMILES CC(C)c1ccc(cc1)\N=N/c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)cc1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580799
(CHEMBL5077172)Show SMILES Cc1cc(ccc1OCCc1ccc(OC(C)(C)C(O)=O)cc1)\N=N\c1ccccc1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 540 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580800
(CHEMBL5087538)Show SMILES Cc1cc(ccc1OCCc1ccc(OC(C)(C)C(O)=O)cc1)\N=N/c1ccccc1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580801
(CHEMBL5079792)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2Cl)\N=N\c2ccccc2)cc1)C(O)=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580802
(CHEMBL5093897)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2Cl)\N=N/c2ccccc2)cc1)C(O)=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580803
(CHEMBL5075710)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2C(F)(F)F)\N=N\c2ccccc2)cc1)C(O)=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580804
(CHEMBL5078096)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2C(F)(F)F)\N=N/c2ccccc2)cc1)C(O)=O | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 310 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580805
(CHEMBL5078989)Show SMILES Cc1ccc(cc1)\N=N\c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)c(C)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580806
(CHEMBL5090373)Show SMILES Cc1ccc(cc1)\N=N/c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)c(C)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 800 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580807
(CHEMBL5091066)Show SMILES Cc1ccc(cc1)\N=N\c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)c(c1)C(F)(F)F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 113 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580808
(CHEMBL5090355)Show SMILES Cc1ccc(cc1)\N=N/c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)c(c1)C(F)(F)F | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 410 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580809
(CHEMBL5090762)Show SMILES Cc1ccc(cc1)\N=N\c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)c(Cl)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50580810
(CHEMBL5090334)Show SMILES Cc1ccc(cc1)\N=N/c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)c(Cl)c1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 380 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARdelta LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50401993
(CHEMBL2204696)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C24H24N2O4/c1-24(2,23(27)28)30-22-12-8-18(9-13-22)16-17-29-21-14-10-20(11-15-21)26-25-19-6-4-3-5-7-19/h3-15H,16-17H2,1-2H3,(H,27,28)/b26-25+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 2.67E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50580792
(CHEMBL5087457)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N/c2ccccc2)cc1)C(O)=O | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50401994
(CHEMBL2204695)Show SMILES CC(C)(Oc1ccc(COc2ccc(cc2)\N=N\c2ccccc2)cc1)C(O)=O Show InChI InChI=1S/C23H22N2O4/c1-23(2,22(26)27)29-21-12-8-17(9-13-21)16-28-20-14-10-19(11-15-20)25-24-18-6-4-3-5-7-18/h3-15H,16H2,1-2H3,(H,26,27)/b25-24+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50580793
(CHEMBL5079941)Show SMILES CC(C)(Oc1ccc(COc2ccc(cc2)\N=N/c2ccccc2)cc1)C(O)=O | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50580794
(CHEMBL5090949)Show SMILES Cc1ccc(cc1)\N=N\c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50580795
(CHEMBL5075561)Show SMILES Cc1ccc(cc1)\N=N/c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50535438
(CHEMBL4471853)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C24H23ClN2O4/c1-24(2,23(28)29)31-22-11-3-17(4-12-22)15-16-30-21-13-9-20(10-14-21)27-26-19-7-5-18(25)6-8-19/h3-14H,15-16H2,1-2H3,(H,28,29)/b27-26+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50580796
(CHEMBL5078286)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N/c2ccc(Cl)cc2)cc1)C(O)=O | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50580797
(CHEMBL5085675)Show SMILES CC(C)c1ccc(cc1)\N=N\c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50580798
(CHEMBL5093865)Show SMILES CC(C)c1ccc(cc1)\N=N/c1ccc(OCCc2ccc(OC(C)(C)C(O)=O)cc2)cc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50580799
(CHEMBL5077172)Show SMILES Cc1cc(ccc1OCCc1ccc(OC(C)(C)C(O)=O)cc1)\N=N\c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50580800
(CHEMBL5087538)Show SMILES Cc1cc(ccc1OCCc1ccc(OC(C)(C)C(O)=O)cc1)\N=N/c1ccccc1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50580801
(CHEMBL5079792)Show SMILES CC(C)(Oc1ccc(CCOc2ccc(cc2Cl)\N=N\c2ccccc2)cc1)C(O)=O | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 820 | n/a | n/a | n/a | n/a |
TBA
| Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT |
More data for this Ligand-Target Pair | |