BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor gamma' and Ligand = 'BDBM50401993'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50401993 (CHEMBL2204696) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at Gal4-fused human PPARgamma LBD transfected in HEK293T cells assessed as transcriptional activation incubated for 14 to 16 hrs by ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00810 BindingDB Entry DOI: 10.7270/Q2N87FNT
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50401993 (CHEMBL2204696) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					Assay Description Transactivation of human GAL4-fused PPARgamma ligand binding domain transfected in HEK293 cells after 18 hrs by dual luciferase reporter gene assay				Bioorg Med Chem Lett 22: 7662-6 (2012) Article DOI: 10.1016/j.bmcl.2012.09.111 BindingDB Entry DOI: 10.7270/Q2639QW8
Universit£ degli Studi G. d'Annunzio Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)