Compile Data Set for Download or QSAR

Found 305 hits with Last Name = 'srinivasan' and Initial = 'k'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542790 (CHEMBL4647584) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C46H80N18O11/c1-4-25(2)33(43(72)58-26(3)38(50)68)61-41(70)29(12-9-17-54-46(51)52)59-40(69)28(11-5-6-15-47)60-42(71)30-13-10-19-63(30)32(65)21-53-16-7-8-18-62(20-14-27(48)45(73)74)22-31-35(66)36(67)44(75-31)64-24-57-34-37(49)55-23-56-39(34)64/h23-31,33,35-36,44,53,66-67H,4-22,47-48H2,1-3H3,(H2,50,68)(H,58,72)(H,59,69)(H,60,71)(H,61,70)(H,73,74)(H2,49,55,56)(H4,51,52,54)/t25-,26-,27-,28-,29-,30-,31+,33-,35+,36+,44+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 120 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence ...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542790 (CHEMBL4647584) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C46H80N18O11/c1-4-25(2)33(43(72)58-26(3)38(50)68)61-41(70)29(12-9-17-54-46(51)52)59-40(69)28(11-5-6-15-47)60-42(71)30-13-10-19-63(30)32(65)21-53-16-7-8-18-62(20-14-27(48)45(73)74)22-31-35(66)36(67)44(75-31)64-24-57-34-37(49)55-23-56-39(34)64/h23-31,33,35-36,44,53,66-67H,4-22,47-48H2,1-3H3,(H2,50,68)(H,58,72)(H,59,69)(H,60,71)(H,61,70)(H,73,74)(H2,49,55,56)(H4,51,52,54)/t25-,26-,27-,28-,29-,30-,31+,33-,35+,36+,44+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 30 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542790 (CHEMBL4647584) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C46H80N18O11/c1-4-25(2)33(43(72)58-26(3)38(50)68)61-41(70)29(12-9-17-54-46(51)52)59-40(69)28(11-5-6-15-47)60-42(71)30-13-10-19-63(30)32(65)21-53-16-7-8-18-62(20-14-27(48)45(73)74)22-31-35(66)36(67)44(75-31)64-24-57-34-37(49)55-23-56-39(34)64/h23-31,33,35-36,44,53,66-67H,4-22,47-48H2,1-3H3,(H2,50,68)(H,58,72)(H,59,69)(H,60,71)(H,61,70)(H,73,74)(H2,49,55,56)(H4,51,52,54)/t25-,26-,27-,28-,29-,30-,31+,33-,35+,36+,44+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 90 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542790 (CHEMBL4647584) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C46H80N18O11/c1-4-25(2)33(43(72)58-26(3)38(50)68)61-41(70)29(12-9-17-54-46(51)52)59-40(69)28(11-5-6-15-47)60-42(71)30-13-10-19-63(30)32(65)21-53-16-7-8-18-62(20-14-27(48)45(73)74)22-31-35(66)36(67)44(75-31)64-24-57-34-37(49)55-23-56-39(34)64/h23-31,33,35-36,44,53,66-67H,4-22,47-48H2,1-3H3,(H2,50,68)(H,58,72)(H,59,69)(H,60,71)(H,61,70)(H,73,74)(H2,49,55,56)(H4,51,52,54)/t25-,26-,27-,28-,29-,30-,31+,33-,35+,36+,44+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 60 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542789 (CHEMBL4647726) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C45H78N18O11/c1-4-24(2)32(42(71)57-25(3)37(49)67)60-40(69)28(11-7-16-53-45(50)51)58-39(68)27(10-5-6-14-46)59-41(70)29-12-8-18-62(29)31(64)20-52-15-9-17-61(19-13-26(47)44(72)73)21-30-34(65)35(66)43(74-30)63-23-56-33-36(48)54-22-55-38(33)63/h22-30,32,34-35,43,52,65-66H,4-21,46-47H2,1-3H3,(H2,49,67)(H,57,71)(H,58,68)(H,59,70)(H,60,69)(H,72,73)(H2,48,54,55)(H4,50,51,53)/t24-,25-,26-,27-,28-,29-,30+,32-,34+,35+,43+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 60 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542789 (CHEMBL4647726) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C45H78N18O11/c1-4-24(2)32(42(71)57-25(3)37(49)67)60-40(69)28(11-7-16-53-45(50)51)58-39(68)27(10-5-6-14-46)59-41(70)29-12-8-18-62(29)31(64)20-52-15-9-17-61(19-13-26(47)44(72)73)21-30-34(65)35(66)43(74-30)63-23-56-33-36(48)54-22-55-38(33)63/h22-30,32,34-35,43,52,65-66H,4-21,46-47H2,1-3H3,(H2,49,67)(H,57,71)(H,58,68)(H,59,70)(H,60,69)(H,72,73)(H2,48,54,55)(H4,50,51,53)/t24-,25-,26-,27-,28-,29-,30+,32-,34+,35+,43+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 120 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence ...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542789 (CHEMBL4647726) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C45H78N18O11/c1-4-24(2)32(42(71)57-25(3)37(49)67)60-40(69)28(11-7-16-53-45(50)51)58-39(68)27(10-5-6-14-46)59-41(70)29-12-8-18-62(29)31(64)20-52-15-9-17-61(19-13-26(47)44(72)73)21-30-34(65)35(66)43(74-30)63-23-56-33-36(48)54-22-55-38(33)63/h22-30,32,34-35,43,52,65-66H,4-21,46-47H2,1-3H3,(H2,49,67)(H,57,71)(H,58,68)(H,59,70)(H,60,69)(H,72,73)(H2,48,54,55)(H4,50,51,53)/t24-,25-,26-,27-,28-,29-,30+,32-,34+,35+,43+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 30 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542789 (CHEMBL4647726) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C45H78N18O11/c1-4-24(2)32(42(71)57-25(3)37(49)67)60-40(69)28(11-7-16-53-45(50)51)58-39(68)27(10-5-6-14-46)59-41(70)29-12-8-18-62(29)31(64)20-52-15-9-17-61(19-13-26(47)44(72)73)21-30-34(65)35(66)43(74-30)63-23-56-33-36(48)54-22-55-38(33)63/h22-30,32,34-35,43,52,65-66H,4-21,46-47H2,1-3H3,(H2,49,67)(H,57,71)(H,58,68)(H,59,70)(H,60,69)(H,72,73)(H2,48,54,55)(H4,50,51,53)/t24-,25-,26-,27-,28-,29-,30+,32-,34+,35+,43+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 90 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542788 (CHEMBL4645959) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C44H76N18O11/c1-4-23(2)31(41(70)56-24(3)36(48)66)59-39(68)27(10-7-14-52-44(49)50)57-38(67)26(9-5-6-13-45)58-40(69)28-11-8-16-61(28)30(63)19-51-15-18-60(17-12-25(46)43(71)72)20-29-33(64)34(65)42(73-29)62-22-55-32-35(47)53-21-54-37(32)62/h21-29,31,33-34,42,51,64-65H,4-20,45-46H2,1-3H3,(H2,48,66)(H,56,70)(H,57,67)(H,58,69)(H,59,68)(H,71,72)(H2,47,53,54)(H4,49,50,52)/t23-,24-,25-,26-,27-,28-,29+,31-,33+,34+,42+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 90 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542788 (CHEMBL4645959) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C44H76N18O11/c1-4-23(2)31(41(70)56-24(3)36(48)66)59-39(68)27(10-7-14-52-44(49)50)57-38(67)26(9-5-6-13-45)58-40(69)28-11-8-16-61(28)30(63)19-51-15-18-60(17-12-25(46)43(71)72)20-29-33(64)34(65)42(73-29)62-22-55-32-35(47)53-21-54-37(32)62/h21-29,31,33-34,42,51,64-65H,4-20,45-46H2,1-3H3,(H2,48,66)(H,56,70)(H,57,67)(H,58,69)(H,59,68)(H,71,72)(H2,47,53,54)(H4,49,50,52)/t23-,24-,25-,26-,27-,28-,29+,31-,33+,34+,42+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 120 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence ...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542788 (CHEMBL4645959) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C44H76N18O11/c1-4-23(2)31(41(70)56-24(3)36(48)66)59-39(68)27(10-7-14-52-44(49)50)57-38(67)26(9-5-6-13-45)58-40(69)28-11-8-16-61(28)30(63)19-51-15-18-60(17-12-25(46)43(71)72)20-29-33(64)34(65)42(73-29)62-22-55-32-35(47)53-21-54-37(32)62/h21-29,31,33-34,42,51,64-65H,4-20,45-46H2,1-3H3,(H2,48,66)(H,56,70)(H,57,67)(H,58,69)(H,59,68)(H,71,72)(H2,47,53,54)(H4,49,50,52)/t23-,24-,25-,26-,27-,28-,29+,31-,33+,34+,42+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 30 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542788 (CHEMBL4645959) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C44H76N18O11/c1-4-23(2)31(41(70)56-24(3)36(48)66)59-39(68)27(10-7-14-52-44(49)50)57-38(67)26(9-5-6-13-45)58-40(69)28-11-8-16-61(28)30(63)19-51-15-18-60(17-12-25(46)43(71)72)20-29-33(64)34(65)42(73-29)62-22-55-32-35(47)53-21-54-37(32)62/h21-29,31,33-34,42,51,64-65H,4-20,45-46H2,1-3H3,(H2,48,66)(H,56,70)(H,57,67)(H,58,69)(H,59,68)(H,71,72)(H2,47,53,54)(H4,49,50,52)/t23-,24-,25-,26-,27-,28-,29+,31-,33+,34+,42+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 60 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542790 (CHEMBL4647584) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C46H80N18O11/c1-4-25(2)33(43(72)58-26(3)38(50)68)61-41(70)29(12-9-17-54-46(51)52)59-40(69)28(11-5-6-15-47)60-42(71)30-13-10-19-63(30)32(65)21-53-16-7-8-18-62(20-14-27(48)45(73)74)22-31-35(66)36(67)44(75-31)64-24-57-34-37(49)55-23-56-39(34)64/h23-31,33,35-36,44,53,66-67H,4-22,47-48H2,1-3H3,(H2,50,68)(H,58,72)(H,59,69)(H,60,71)(H,61,70)(H,73,74)(H2,49,55,56)(H4,51,52,54)/t25-,26-,27-,28-,29-,30-,31+,33-,35+,36+,44+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542789 (CHEMBL4647726) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C45H78N18O11/c1-4-24(2)32(42(71)57-25(3)37(49)67)60-40(69)28(11-7-16-53-45(50)51)58-39(68)27(10-5-6-14-46)59-41(70)29-12-8-18-62(29)31(64)20-52-15-9-17-61(19-13-26(47)44(72)73)21-30-34(65)35(66)43(74-30)63-23-56-33-36(48)54-22-55-38(33)63/h22-30,32,34-35,43,52,65-66H,4-21,46-47H2,1-3H3,(H2,49,67)(H,57,71)(H,58,68)(H,59,70)(H,60,69)(H,72,73)(H2,48,54,55)(H4,50,51,53)/t24-,25-,26-,27-,28-,29-,30+,32-,34+,35+,43+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542788 (CHEMBL4645959) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C44H76N18O11/c1-4-23(2)31(41(70)56-24(3)36(48)66)59-39(68)27(10-7-14-52-44(49)50)57-38(67)26(9-5-6-13-45)58-40(69)28-11-8-16-61(28)30(63)19-51-15-18-60(17-12-25(46)43(71)72)20-29-33(64)34(65)42(73-29)62-22-55-32-35(47)53-21-54-37(32)62/h21-29,31,33-34,42,51,64-65H,4-20,45-46H2,1-3H3,(H2,48,66)(H,56,70)(H,57,67)(H,58,69)(H,59,68)(H,71,72)(H2,47,53,54)(H4,49,50,52)/t23-,24-,25-,26-,27-,28-,29+,31-,33+,34+,42+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Time dependent inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence a...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542790 (CHEMBL4647584) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C46H80N18O11/c1-4-25(2)33(43(72)58-26(3)38(50)68)61-41(70)29(12-9-17-54-46(51)52)59-40(69)28(11-5-6-15-47)60-42(71)30-13-10-19-63(30)32(65)21-53-16-7-8-18-62(20-14-27(48)45(73)74)22-31-35(66)36(67)44(75-31)64-24-57-34-37(49)55-23-56-39(34)64/h23-31,33,35-36,44,53,66-67H,4-22,47-48H2,1-3H3,(H2,50,68)(H,58,72)(H,59,69)(H,60,71)(H,61,70)(H,73,74)(H2,49,55,56)(H4,51,52,54)/t25-,26-,27-,28-,29-,30-,31+,33-,35+,36+,44+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assay				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542793 (CHEMBL4635903) Show SMILES NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNCCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C37H64N16O9/c38-11-2-1-7-23(33(58)49-22(31(41)57)8-5-13-45-37(42)43)50-34(59)24-9-6-15-52(24)26(54)17-44-12-3-4-14-51(16-10-21(39)36(60)61)18-25-28(55)29(56)35(62-25)53-20-48-27-30(40)46-19-47-32(27)53/h19-25,28-29,35,44,55-56H,1-18,38-39H2,(H2,41,57)(H,49,58)(H,50,59)(H,60,61)(H2,40,46,47)(H4,42,43,45)/t21-,22-,23-,24-,25+,28+,29+,35+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assay				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542789 (CHEMBL4647726) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C45H78N18O11/c1-4-24(2)32(42(71)57-25(3)37(49)67)60-40(69)28(11-7-16-53-45(50)51)58-39(68)27(10-5-6-14-46)59-41(70)29-12-8-18-62(29)31(64)20-52-15-9-17-61(19-13-26(47)44(72)73)21-30-34(65)35(66)43(74-30)63-23-56-33-36(48)54-22-55-38(33)63/h22-30,32,34-35,43,52,65-66H,4-21,46-47H2,1-3H3,(H2,49,67)(H,57,71)(H,58,68)(H,59,70)(H,60,69)(H,72,73)(H2,48,54,55)(H4,50,51,53)/t24-,25-,26-,27-,28-,29-,30+,32-,34+,35+,43+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assay				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542792 (CHEMBL4636288) Show SMILES NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C36H62N16O9/c37-10-2-1-6-22(32(57)48-21(30(40)56)7-3-12-44-36(41)42)49-33(58)23-8-4-14-51(23)25(53)16-43-11-5-13-50(15-9-20(38)35(59)60)17-24-27(54)28(55)34(61-24)52-19-47-26-29(39)45-18-46-31(26)52/h18-24,27-28,34,43,54-55H,1-17,37-38H2,(H2,40,56)(H,48,57)(H,49,58)(H,59,60)(H2,39,45,46)(H4,41,42,44)/t20-,21-,22-,23-,24+,27+,28+,34+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assay				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542788 (CHEMBL4645959) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)CNCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](C)C(N)=O |r| Show InChI InChI=1S/C44H76N18O11/c1-4-23(2)31(41(70)56-24(3)36(48)66)59-39(68)27(10-7-14-52-44(49)50)57-38(67)26(9-5-6-13-45)58-40(69)28-11-8-16-61(28)30(63)19-51-15-18-60(17-12-25(46)43(71)72)20-29-33(64)34(65)42(73-29)62-22-55-32-35(47)53-21-54-37(32)62/h21-29,31,33-34,42,51,64-65H,4-20,45-46H2,1-3H3,(H2,48,66)(H,56,70)(H,57,67)(H,58,69)(H,59,68)(H,71,72)(H2,47,53,54)(H4,49,50,52)/t23-,24-,25-,26-,27-,28-,29+,31-,33+,34+,42+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assay				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542791 (CHEMBL4633108) Show SMILES NCCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O |r| Show InChI InChI=1S/C35H60N16O9/c36-9-2-1-5-21(31(56)47-20(29(39)55)6-3-10-43-35(40)41)48-32(57)22-7-4-12-50(22)24(52)15-42-11-14-49(13-8-19(37)34(58)59)16-23-26(53)27(54)33(60-23)51-18-46-25-28(38)44-17-45-30(25)51/h17-23,26-27,33,42,53-54H,1-16,36-37H2,(H2,39,55)(H,47,56)(H,48,57)(H,58,59)(H2,38,44,45)(H4,40,41,43)/t19-,20-,21-,22-,23+,26+,27+,33+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assay				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50523492 (CHEMBL4453066) Show SMILES N[C@@H](CCN(CCCNCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(N)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C45H79N23O12/c46-23(42(78)79)10-17-66(19-29-32(71)33(72)41(80-29)68-22-61-31-34(47)59-21-60-36(31)68)15-5-11-55-18-30(70)67-16-4-9-28(67)40(77)64-26(8-3-14-58-45(53)54)38(75)62-24(6-1-12-56-43(49)50)37(74)63-25(7-2-13-57-44(51)52)39(76)65-27(20-69)35(48)73/h21-29,32-33,41,55,69,71-72H,1-20,46H2,(H2,48,73)(H,62,75)(H,63,74)(H,64,77)(H,65,76)(H,78,79)(H2,47,59,60)(H4,49,50,56)(H4,51,52,57)(H4,53,54,58)/t23-,24-,25-,26-,27-,28-,29+,32+,33+,41+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of NTMT1 (unknown origin)				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542795 (CHEMBL2018849) Show SMILES N[C@@H](CCNC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O |r| Show InChI InChI=1S/C14H21N7O5/c15-6(14(24)25)1-2-17-3-7-9(22)10(23)13(26-7)21-5-20-8-11(16)18-4-19-12(8)21/h4-7,9-10,13,17,22-23H,1-3,15H2,(H,24,25)(H2,16,18,19)/t6-,7+,9+,10+,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition and measured after 20 mins by MALDI-MS methyl...				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
N-terminal Xaa-Pro-Lys N-methyltransferase 1 (Homo sapiens)	BDBM50542794 (CHEMBL4634993) Show SMILES NCCCCN(CC[C@H](N)C(O)=O)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r| Show InChI InChI=1S/C18H30N8O5/c19-4-1-2-5-25(6-3-10(20)18(29)30)7-11-13(27)14(28)17(31-11)26-9-24-12-15(21)22-8-23-16(12)26/h8-11,13-14,17,27-28H,1-7,19-20H2,(H,29,30)(H2,21,22,23)/t10-,11+,13+,14+,17+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of NTMT1 (unknown origin) pre-incubated for 10 mins before GPKRIA peptide substrate addition by SAHH coupled fluorescence assay				J Med Chem 63: 8419-8431 (2020) Article DOI: 10.1021/acs.jmedchem.0c00770 BindingDB Entry DOI: 10.7270/Q2B85CQB
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183574 (CHEMBL3822727) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C153H237N41O47/c1-20-24-41-91(174-132(221)94(46-48-115(204)205)175-140(229)105(62-117(208)209)186-147(236)109(70-196)189-137(226)99(55-83-36-27-25-28-37-83)181-146(235)108(69-195)171-114(203)68-166-129(218)104(61-116(206)207)170-113(202)67-165-128(217)88(155)58-86-66-162-71-167-86)130(219)183-103(60-112(158)201)145(234)194-124(82(19)198)152(241)192-122(78(15)23-4)150(239)187-97(53-74(9)10)136(225)185-107(64-119(212)213)141(230)178-96(52-73(7)8)135(224)177-95(51-72(5)6)134(223)169-79(16)126(215)168-80(17)127(216)173-92(44-35-50-163-153(160)161)131(220)184-106(63-118(210)211)142(231)180-100(56-84-38-29-26-30-39-84)144(233)191-121(77(14)22-3)149(238)188-102(59-111(157)200)139(228)182-101(57-85-65-164-89-42-32-31-40-87(85)89)138(227)179-98(54-75(11)12)143(232)190-120(76(13)21-2)148(237)176-93(45-47-110(156)199)133(222)193-123(81(18)197)151(240)172-90(125(159)214)43-33-34-49-154/h25-32,36-40,42,65-66,71-82,88,90-109,120-124,164,195-198H,20-24,33-35,41,43-64,67-70,154-155H2,1-19H3,(H2,156,199)(H2,157,200)(H2,158,201)(H2,159,214)(H,162,167)(H,165,217)(H,166,218)(H,168,215)(H,169,223)(H,170,202)(H,171,203)(H,172,240)(H,173,216)(H,174,221)(H,175,229)(H,176,237)(H,177,224)(H,178,230)(H,179,227)(H,180,231)(H,181,235)(H,182,228)(H,183,219)(H,184,220)(H,185,225)(H,186,236)(H,187,239)(H,188,238)(H,189,226)(H,190,232)(H,191,233)(H,192,241)(H,193,222)(H,194,234)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H4,160,161,163)/t76-,77-,78-,79-,80-,81+,82+,88-,90-,91?,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,120-,121-,122-,123-,124-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183575 (CHEMBL3823786) Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(CC1CCCCC1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C156H241N41O47/c1-18-22-44-94(177-135(224)97(49-51-118(207)208)178-143(232)108(65-120(211)212)189-150(239)112(73-199)192-140(229)102(58-86-39-28-24-29-40-86)184-149(238)111(72-198)174-117(206)71-169-132(221)107(64-119(209)210)173-116(205)70-168-131(220)91(158)61-89-69-165-74-170-89)133(222)186-106(63-115(161)204)148(237)197-127(84(17)201)155(244)195-125(80(13)21-4)153(242)190-99(55-76(7)8)138(227)188-110(67-122(215)216)145(234)182-101(57-85-37-26-23-27-38-85)139(228)180-98(54-75(5)6)137(226)172-81(14)129(218)171-82(15)130(219)176-95(47-36-53-166-156(163)164)134(223)187-109(66-121(213)214)144(233)183-103(59-87-41-30-25-31-42-87)147(236)194-124(79(12)20-3)152(241)191-105(62-114(160)203)142(231)185-104(60-88-68-167-92-45-33-32-43-90(88)92)141(230)181-100(56-77(9)10)146(235)193-123(78(11)19-2)151(240)179-96(48-50-113(159)202)136(225)196-126(83(16)200)154(243)175-93(128(162)217)46-34-35-52-157/h24-25,28-33,39-43,45,68-69,74-85,91,93-112,123-127,167,198-201H,18-23,26-27,34-38,44,46-67,70-73,157-158H2,1-17H3,(H2,159,202)(H2,160,203)(H2,161,204)(H2,162,217)(H,165,170)(H,168,220)(H,169,221)(H,171,218)(H,172,226)(H,173,205)(H,174,206)(H,175,243)(H,176,219)(H,177,224)(H,178,232)(H,179,240)(H,180,228)(H,181,230)(H,182,234)(H,183,233)(H,184,238)(H,185,231)(H,186,222)(H,187,223)(H,188,227)(H,189,239)(H,190,242)(H,191,241)(H,192,229)(H,193,235)(H,194,236)(H,195,244)(H,196,225)(H,197,237)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H4,163,164,166)/t78-,79-,80-,81-,82-,83+,84+,91-,93-,94?,95-,96-,97-,98-,99-,100-,101?,102?,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,123-,124-,125-,126-,127-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183576 (CHEMBL3823643) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C156H235N41O47/c1-18-22-44-94(177-135(224)97(49-51-118(207)208)178-143(232)108(65-120(211)212)189-150(239)112(73-199)192-140(229)102(58-86-39-28-24-29-40-86)184-149(238)111(72-198)174-117(206)71-169-132(221)107(64-119(209)210)173-116(205)70-168-131(220)91(158)61-89-69-165-74-170-89)133(222)186-106(63-115(161)204)148(237)197-127(84(17)201)155(244)195-125(80(13)21-4)153(242)190-99(55-76(7)8)138(227)188-110(67-122(215)216)145(234)182-101(57-85-37-26-23-27-38-85)139(228)180-98(54-75(5)6)137(226)172-81(14)129(218)171-82(15)130(219)176-95(47-36-53-166-156(163)164)134(223)187-109(66-121(213)214)144(233)183-103(59-87-41-30-25-31-42-87)147(236)194-124(79(12)20-3)152(241)191-105(62-114(160)203)142(231)185-104(60-88-68-167-92-45-33-32-43-90(88)92)141(230)181-100(56-77(9)10)146(235)193-123(78(11)19-2)151(240)179-96(48-50-113(159)202)136(225)196-126(83(16)200)154(243)175-93(128(162)217)46-34-35-52-157/h23-33,37-43,45,68-69,74-84,91,93-112,123-127,167,198-201H,18-22,34-36,44,46-67,70-73,157-158H2,1-17H3,(H2,159,202)(H2,160,203)(H2,161,204)(H2,162,217)(H,165,170)(H,168,220)(H,169,221)(H,171,218)(H,172,226)(H,173,205)(H,174,206)(H,175,243)(H,176,219)(H,177,224)(H,178,232)(H,179,240)(H,180,228)(H,181,230)(H,182,234)(H,183,233)(H,184,238)(H,185,231)(H,186,222)(H,187,223)(H,188,227)(H,189,239)(H,190,242)(H,191,241)(H,192,229)(H,193,235)(H,194,236)(H,195,244)(H,196,225)(H,197,237)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H4,163,164,166)/t78-,79-,80-,81-,82-,83+,84+,91-,93-,94?,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,123-,124-,125-,126-,127-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.140	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183577 (CHEMBL3822636) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C156H235N41O48/c1-18-22-39-94(177-135(225)97(48-50-118(208)209)178-143(233)108(64-120(212)213)189-150(240)112(72-199)192-140(230)101(56-84-34-25-23-26-35-84)184-149(239)111(71-198)174-117(207)70-169-132(222)107(63-119(210)211)173-116(206)69-168-131(221)91(158)60-88-68-165-73-170-88)133(223)186-106(62-115(161)205)148(238)197-127(83(17)201)155(245)195-125(79(13)21-4)153(243)190-99(54-75(7)8)138(228)188-110(66-122(216)217)145(235)182-102(58-86-43-45-89(202)46-44-86)139(229)180-98(53-74(5)6)137(227)172-80(14)129(219)171-81(15)130(220)176-95(42-33-52-166-156(163)164)134(224)187-109(65-121(214)215)144(234)183-103(57-85-36-27-24-28-37-85)147(237)194-124(78(12)20-3)152(242)191-105(61-114(160)204)142(232)185-104(59-87-67-167-92-40-30-29-38-90(87)92)141(231)181-100(55-76(9)10)146(236)193-123(77(11)19-2)151(241)179-96(47-49-113(159)203)136(226)196-126(82(16)200)154(244)175-93(128(162)218)41-31-32-51-157/h23-30,34-38,40,43-46,67-68,73-83,91,93-112,123-127,167,198-202H,18-22,31-33,39,41-42,47-66,69-72,157-158H2,1-17H3,(H2,159,203)(H2,160,204)(H2,161,205)(H2,162,218)(H,165,170)(H,168,221)(H,169,222)(H,171,219)(H,172,227)(H,173,206)(H,174,207)(H,175,244)(H,176,220)(H,177,225)(H,178,233)(H,179,241)(H,180,229)(H,181,231)(H,182,235)(H,183,234)(H,184,239)(H,185,232)(H,186,223)(H,187,224)(H,188,228)(H,189,240)(H,190,243)(H,191,242)(H,192,230)(H,193,236)(H,194,237)(H,195,245)(H,196,226)(H,197,238)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,163,164,166)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94?,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,123-,124-,125-,126-,127-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.110	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183578 (CHEMBL3824197) Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccc(Cl)cc1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C156H234ClN41O47/c1-18-22-39-94(178-135(225)97(48-50-118(208)209)179-143(233)108(64-120(212)213)190-150(240)112(72-200)193-140(230)101(56-84-34-25-23-26-35-84)185-149(239)111(71-199)175-117(207)70-170-132(222)107(63-119(210)211)174-116(206)69-169-131(221)91(159)60-89-68-166-73-171-89)133(223)187-106(62-115(162)205)148(238)198-127(83(17)202)155(245)196-125(79(13)21-4)153(243)191-99(54-75(7)8)138(228)189-110(66-122(216)217)145(235)183-102(58-86-43-45-88(157)46-44-86)139(229)181-98(53-74(5)6)137(227)173-80(14)129(219)172-81(15)130(220)177-95(42-33-52-167-156(164)165)134(224)188-109(65-121(214)215)144(234)184-103(57-85-36-27-24-28-37-85)147(237)195-124(78(12)20-3)152(242)192-105(61-114(161)204)142(232)186-104(59-87-67-168-92-40-30-29-38-90(87)92)141(231)182-100(55-76(9)10)146(236)194-123(77(11)19-2)151(241)180-96(47-49-113(160)203)136(226)197-126(82(16)201)154(244)176-93(128(163)218)41-31-32-51-158/h23-30,34-38,40,43-46,67-68,73-83,91,93-112,123-127,168,199-202H,18-22,31-33,39,41-42,47-66,69-72,158-159H2,1-17H3,(H2,160,203)(H2,161,204)(H2,162,205)(H2,163,218)(H,166,171)(H,169,221)(H,170,222)(H,172,219)(H,173,227)(H,174,206)(H,175,207)(H,176,244)(H,177,220)(H,178,225)(H,179,233)(H,180,241)(H,181,229)(H,182,231)(H,183,235)(H,184,234)(H,185,239)(H,186,232)(H,187,223)(H,188,224)(H,189,228)(H,190,240)(H,191,243)(H,192,242)(H,193,230)(H,194,236)(H,195,237)(H,196,245)(H,197,226)(H,198,238)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,164,165,167)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94?,95-,96-,97-,98-,99-,100-,101?,102?,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,123-,124-,125-,126-,127-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.220	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183579 (CHEMBL3824278) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)NC(Cc1cccs1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C154H233N41O47S/c1-18-22-41-92(175-133(222)95(46-48-116(205)206)176-141(230)106(63-118(209)210)187-148(237)110(71-197)190-137(226)99(55-83-35-25-23-26-36-83)181-147(236)109(70-196)172-115(204)69-167-130(219)105(62-117(207)208)171-114(203)68-166-129(218)89(156)58-86-67-163-72-168-86)131(220)184-104(61-113(159)202)146(235)195-125(82(17)199)153(242)193-123(78(13)21-4)151(240)188-97(53-74(7)8)136(225)186-108(65-120(213)214)143(232)183-102(59-87-39-34-51-243-87)139(228)178-96(52-73(5)6)135(224)170-79(14)127(216)169-80(15)128(217)174-93(44-33-50-164-154(161)162)132(221)185-107(64-119(211)212)142(231)180-100(56-84-37-27-24-28-38-84)145(234)192-122(77(12)20-3)150(239)189-103(60-112(158)201)140(229)182-101(57-85-66-165-90-42-30-29-40-88(85)90)138(227)179-98(54-75(9)10)144(233)191-121(76(11)19-2)149(238)177-94(45-47-111(157)200)134(223)194-124(81(16)198)152(241)173-91(126(160)215)43-31-32-49-155/h23-30,34-40,42,51,66-67,72-82,89,91-110,121-125,165,196-199H,18-22,31-33,41,43-50,52-65,68-71,155-156H2,1-17H3,(H2,157,200)(H2,158,201)(H2,159,202)(H2,160,215)(H,163,168)(H,166,218)(H,167,219)(H,169,216)(H,170,224)(H,171,203)(H,172,204)(H,173,241)(H,174,217)(H,175,222)(H,176,230)(H,177,238)(H,178,228)(H,179,227)(H,180,231)(H,181,236)(H,182,229)(H,183,232)(H,184,220)(H,185,221)(H,186,225)(H,187,237)(H,188,240)(H,189,239)(H,190,226)(H,191,233)(H,192,234)(H,193,242)(H,194,223)(H,195,235)(H,205,206)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H4,161,162,164)/t76-,77-,78-,79-,80-,81+,82+,89-,91-,92?,93-,94-,95-,96-,97-,98-,99-,100-,101-,102?,103-,104-,105-,106-,107-,108-,109-,110-,121-,122-,123-,124-,125-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183580 (CHEMBL3824272) Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccc(N)cc1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C156H236N42O47/c1-18-22-39-94(178-135(225)97(48-50-118(208)209)179-143(233)108(64-120(212)213)190-150(240)112(72-200)193-140(230)101(56-84-34-25-23-26-35-84)185-149(239)111(71-199)175-117(207)70-170-132(222)107(63-119(210)211)174-116(206)69-169-131(221)91(159)60-89-68-166-73-171-89)133(223)187-106(62-115(162)205)148(238)198-127(83(17)202)155(245)196-125(79(13)21-4)153(243)191-99(54-75(7)8)138(228)189-110(66-122(216)217)145(235)183-102(58-86-43-45-88(158)46-44-86)139(229)181-98(53-74(5)6)137(227)173-80(14)129(219)172-81(15)130(220)177-95(42-33-52-167-156(164)165)134(224)188-109(65-121(214)215)144(234)184-103(57-85-36-27-24-28-37-85)147(237)195-124(78(12)20-3)152(242)192-105(61-114(161)204)142(232)186-104(59-87-67-168-92-40-30-29-38-90(87)92)141(231)182-100(55-76(9)10)146(236)194-123(77(11)19-2)151(241)180-96(47-49-113(160)203)136(226)197-126(82(16)201)154(244)176-93(128(163)218)41-31-32-51-157/h23-30,34-38,40,43-46,67-68,73-83,91,93-112,123-127,168,199-202H,18-22,31-33,39,41-42,47-66,69-72,157-159H2,1-17H3,(H2,160,203)(H2,161,204)(H2,162,205)(H2,163,218)(H,166,171)(H,169,221)(H,170,222)(H,172,219)(H,173,227)(H,174,206)(H,175,207)(H,176,244)(H,177,220)(H,178,225)(H,179,233)(H,180,241)(H,181,229)(H,182,231)(H,183,235)(H,184,234)(H,185,239)(H,186,232)(H,187,223)(H,188,224)(H,189,228)(H,190,240)(H,191,243)(H,192,242)(H,193,230)(H,194,236)(H,195,237)(H,196,245)(H,197,226)(H,198,238)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,164,165,167)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94?,95-,96-,97-,98-,99-,100-,101?,102?,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,123-,124-,125-,126-,127-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.130	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183581 (CHEMBL3823082) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C153H233N43O47/c1-18-22-39-91(176-132(223)94(44-46-115(206)207)177-140(231)105(60-117(210)211)188-147(238)109(69-198)191-136(227)98(52-82-34-25-23-26-35-82)182-146(237)108(68-197)173-114(205)67-167-129(220)104(59-116(208)209)172-113(204)66-166-128(219)88(155)55-85-64-162-70-168-85)130(221)185-103(58-112(158)203)145(236)196-124(81(17)200)152(243)194-122(77(13)21-4)150(241)189-96(50-73(7)8)135(226)187-107(62-119(214)215)142(233)184-101(56-86-65-163-71-169-86)138(229)179-95(49-72(5)6)134(225)171-78(14)126(217)170-79(15)127(218)175-92(42-33-48-164-153(160)161)131(222)186-106(61-118(212)213)141(232)181-99(53-83-36-27-24-28-37-83)144(235)193-121(76(12)20-3)149(240)190-102(57-111(157)202)139(230)183-100(54-84-63-165-89-40-30-29-38-87(84)89)137(228)180-97(51-74(9)10)143(234)192-120(75(11)19-2)148(239)178-93(43-45-110(156)201)133(224)195-123(80(16)199)151(242)174-90(125(159)216)41-31-32-47-154/h23-30,34-38,40,63-65,70-81,88,90-109,120-124,165,197-200H,18-22,31-33,39,41-62,66-69,154-155H2,1-17H3,(H2,156,201)(H2,157,202)(H2,158,203)(H2,159,216)(H,162,168)(H,163,169)(H,166,219)(H,167,220)(H,170,217)(H,171,225)(H,172,204)(H,173,205)(H,174,242)(H,175,218)(H,176,223)(H,177,231)(H,178,239)(H,179,229)(H,180,228)(H,181,232)(H,182,237)(H,183,230)(H,184,233)(H,185,221)(H,186,222)(H,187,226)(H,188,238)(H,189,241)(H,190,240)(H,191,227)(H,192,234)(H,193,235)(H,194,243)(H,195,224)(H,196,236)(H,206,207)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H4,160,161,164)/t75-,76-,77-,78-,79-,80+,81+,88-,90-,91?,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,120-,121-,122-,123-,124-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.420	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183642 (CHEMBL3823126) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)NC(CCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C157H237N41O47/c1-18-22-44-95(178-136(225)99(51-53-119(208)209)180-145(234)110(67-122(214)215)190-151(240)113(74-200)193-141(230)103(59-87-39-28-24-29-40-87)185-150(239)112(73-199)175-118(207)72-170-133(222)108(65-120(210)211)174-117(206)71-169-132(221)92(159)62-90-70-166-75-171-90)134(223)187-107(64-116(162)205)149(238)198-128(85(17)202)156(245)196-126(81(13)21-4)154(243)191-101(57-77(7)8)140(229)189-109(66-121(212)213)144(233)179-97(49-48-86-37-26-23-27-38-86)137(226)182-100(56-76(5)6)139(228)173-82(14)130(219)172-83(15)131(220)177-96(47-36-55-167-157(164)165)135(224)188-111(68-123(216)217)146(235)184-104(60-88-41-30-25-31-42-88)148(237)195-125(80(12)20-3)153(242)192-106(63-115(161)204)143(232)186-105(61-89-69-168-93-45-33-32-43-91(89)93)142(231)183-102(58-78(9)10)147(236)194-124(79(11)19-2)152(241)181-98(50-52-114(160)203)138(227)197-127(84(16)201)155(244)176-94(129(163)218)46-34-35-54-158/h23-33,37-43,45,69-70,75-85,92,94-113,124-128,168,199-202H,18-22,34-36,44,46-68,71-74,158-159H2,1-17H3,(H2,160,203)(H2,161,204)(H2,162,205)(H2,163,218)(H,166,171)(H,169,221)(H,170,222)(H,172,219)(H,173,228)(H,174,206)(H,175,207)(H,176,244)(H,177,220)(H,178,225)(H,179,233)(H,180,234)(H,181,241)(H,182,226)(H,183,231)(H,184,235)(H,185,239)(H,186,232)(H,187,223)(H,188,224)(H,189,229)(H,190,240)(H,191,243)(H,192,242)(H,193,230)(H,194,236)(H,195,237)(H,196,245)(H,197,227)(H,198,238)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,164,165,167)/t79-,80-,81-,82-,83-,84+,85+,92-,94-,95?,96-,97?,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,124-,125-,126-,127-,128-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.110	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183644 (CHEMBL3823936) Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1cccc2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C160H237N41O47/c1-18-22-46-98(181-139(228)101(51-53-122(211)212)182-147(236)112(67-124(215)216)193-154(243)116(75-203)196-143(232)105(59-87-37-25-23-26-38-87)187-153(242)115(74-202)178-121(210)73-173-136(225)111(66-123(213)214)177-120(209)72-172-135(224)95(162)63-92-71-169-76-174-92)137(226)190-110(65-119(165)208)152(241)201-131(86(17)205)159(248)199-129(82(13)21-4)157(246)194-103(57-78(7)8)142(231)192-114(69-126(219)220)149(238)188-107(61-90-43-35-42-89-41-29-30-44-93(89)90)144(233)184-102(56-77(5)6)141(230)176-83(14)133(222)175-84(15)134(223)180-99(49-36-55-170-160(167)168)138(227)191-113(68-125(217)218)148(237)186-106(60-88-39-27-24-28-40-88)151(240)198-128(81(12)20-3)156(245)195-109(64-118(164)207)146(235)189-108(62-91-70-171-96-47-32-31-45-94(91)96)145(234)185-104(58-79(9)10)150(239)197-127(80(11)19-2)155(244)183-100(50-52-117(163)206)140(229)200-130(85(16)204)158(247)179-97(132(166)221)48-33-34-54-161/h23-32,35,37-45,47,70-71,76-86,95,97-116,127-131,171,202-205H,18-22,33-34,36,46,48-69,72-75,161-162H2,1-17H3,(H2,163,206)(H2,164,207)(H2,165,208)(H2,166,221)(H,169,174)(H,172,224)(H,173,225)(H,175,222)(H,176,230)(H,177,209)(H,178,210)(H,179,247)(H,180,223)(H,181,228)(H,182,236)(H,183,244)(H,184,233)(H,185,234)(H,186,237)(H,187,242)(H,188,238)(H,189,235)(H,190,226)(H,191,227)(H,192,231)(H,193,243)(H,194,246)(H,195,245)(H,196,232)(H,197,239)(H,198,240)(H,199,248)(H,200,229)(H,201,241)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H4,167,168,170)/t80-,81-,82-,83-,84-,85+,86+,95-,97-,98?,99-,100-,101-,102-,103-,104-,105?,106-,107?,108-,109-,110-,111-,112-,113-,114-,115-,116-,127-,128-,129-,130-,131-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.190	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183645 (CHEMBL3823818) Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C160H237N41O47/c1-18-22-43-98(181-139(228)101(50-52-122(211)212)182-147(236)112(67-124(215)216)193-154(243)116(75-203)196-144(233)105(59-87-36-25-23-26-37-87)188-153(242)115(74-202)178-121(210)73-173-136(225)111(66-123(213)214)177-120(209)72-172-135(224)95(162)63-93-71-169-76-174-93)137(226)190-110(65-119(165)208)152(241)201-131(86(17)205)159(248)199-129(82(13)21-4)157(246)194-103(56-78(7)8)142(231)192-114(69-126(219)220)149(238)187-107(61-89-47-48-90-40-29-30-41-91(90)58-89)143(232)184-102(55-77(5)6)141(230)176-83(14)133(222)175-84(15)134(223)180-99(46-35-54-170-160(167)168)138(227)191-113(68-125(217)218)148(237)186-106(60-88-38-27-24-28-39-88)151(240)198-128(81(12)20-3)156(245)195-109(64-118(164)207)146(235)189-108(62-92-70-171-96-44-32-31-42-94(92)96)145(234)185-104(57-79(9)10)150(239)197-127(80(11)19-2)155(244)183-100(49-51-117(163)206)140(229)200-130(85(16)204)158(247)179-97(132(166)221)45-33-34-53-161/h23-32,36-42,44,47-48,58,70-71,76-86,95,97-116,127-131,171,202-205H,18-22,33-35,43,45-46,49-57,59-69,72-75,161-162H2,1-17H3,(H2,163,206)(H2,164,207)(H2,165,208)(H2,166,221)(H,169,174)(H,172,224)(H,173,225)(H,175,222)(H,176,230)(H,177,209)(H,178,210)(H,179,247)(H,180,223)(H,181,228)(H,182,236)(H,183,244)(H,184,232)(H,185,234)(H,186,237)(H,187,238)(H,188,242)(H,189,235)(H,190,226)(H,191,227)(H,192,231)(H,193,243)(H,194,246)(H,195,245)(H,196,233)(H,197,239)(H,198,240)(H,199,248)(H,200,229)(H,201,241)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H4,167,168,170)/t80-,81-,82-,83-,84-,85+,86+,95-,97-,98?,99-,100-,101-,102-,103-,104-,105?,106-,107?,108-,109-,110-,111-,112-,113-,114-,115-,116-,127-,128-,129-,130-,131-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.130	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183646 (CHEMBL3823994) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C158H236N42O47/c1-18-22-42-96(180-137(227)99(48-50-120(210)211)181-145(235)110(64-122(214)215)192-152(242)114(73-202)195-141(231)103(56-85-36-25-23-26-37-85)186-151(241)113(72-201)177-119(209)71-172-134(224)109(63-121(212)213)176-118(208)70-171-133(223)92(160)60-89-69-167-74-173-89)135(225)189-108(62-117(163)207)150(240)200-129(84(17)204)157(247)198-127(80(13)21-4)155(245)193-101(54-76(7)8)140(230)191-112(66-124(218)219)147(237)188-106(59-88-68-170-94-44-32-30-41-91(88)94)142(232)183-100(53-75(5)6)139(229)175-81(14)131(221)174-82(15)132(222)179-97(46-35-52-168-158(165)166)136(226)190-111(65-123(216)217)146(236)185-104(57-86-38-27-24-28-39-86)149(239)197-126(79(12)20-3)154(244)194-107(61-116(162)206)144(234)187-105(58-87-67-169-93-43-31-29-40-90(87)93)143(233)184-102(55-77(9)10)148(238)196-125(78(11)19-2)153(243)182-98(47-49-115(161)205)138(228)199-128(83(16)203)156(246)178-95(130(164)220)45-33-34-51-159/h23-32,36-41,43-44,67-69,74-84,92,95-114,125-129,169-170,201-204H,18-22,33-35,42,45-66,70-73,159-160H2,1-17H3,(H2,161,205)(H2,162,206)(H2,163,207)(H2,164,220)(H,167,173)(H,171,223)(H,172,224)(H,174,221)(H,175,229)(H,176,208)(H,177,209)(H,178,246)(H,179,222)(H,180,227)(H,181,235)(H,182,243)(H,183,232)(H,184,233)(H,185,236)(H,186,241)(H,187,234)(H,188,237)(H,189,225)(H,190,226)(H,191,230)(H,192,242)(H,193,245)(H,194,244)(H,195,231)(H,196,238)(H,197,239)(H,198,247)(H,199,228)(H,200,240)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H,218,219)(H4,165,166,168)/t78-,79-,80-,81-,82-,83+,84+,92-,95-,96?,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,125-,126-,127-,128-,129-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.150	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183647 (CHEMBL3822809) Show SMILES CCCCC(NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(Cc1ccccc1)NC(=O)C(CO)NC(=O)CNC(=O)C(CC(O)=O)NC(=O)CNC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(CC(N)=O)C(=O)NC(C(C)O)C(=O)NC(C(C)CC)C(=O)NC(CC(C)C)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccc(cc1)-c1ccccc1)C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(=O)NC(CC(O)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(C(C)CC)C(=O)NC(CC(N)=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CCC(N)=O)C(=O)NC(C(C)O)C(=O)NC(CCCCN)C(N)=O Show InChI InChI=1S/C162H239N41O47/c1-18-22-44-100(183-141(230)103(53-55-124(213)214)184-149(238)114(69-126(217)218)195-156(245)118(77-205)198-146(235)107(61-89-37-26-23-27-38-89)190-155(244)117(76-204)180-123(212)75-175-138(227)113(68-125(215)216)179-122(211)74-174-137(226)97(164)65-95-73-171-78-176-95)139(228)192-112(67-121(167)210)154(243)203-133(88(17)207)161(250)201-131(84(13)21-4)159(248)196-105(59-80(7)8)144(233)194-116(71-128(221)222)151(240)188-108(63-91-48-50-93(51-49-91)92-41-30-25-31-42-92)145(234)186-104(58-79(5)6)143(232)178-85(14)135(224)177-86(15)136(225)182-101(47-36-57-172-162(169)170)140(229)193-115(70-127(219)220)150(239)189-109(62-90-39-28-24-29-40-90)153(242)200-130(83(12)20-3)158(247)197-111(66-120(166)209)148(237)191-110(64-94-72-173-98-45-33-32-43-96(94)98)147(236)187-106(60-81(9)10)152(241)199-129(82(11)19-2)157(246)185-102(52-54-119(165)208)142(231)202-132(87(16)206)160(249)181-99(134(168)223)46-34-35-56-163/h23-33,37-43,45,48-51,72-73,78-88,97,99-118,129-133,173,204-207H,18-22,34-36,44,46-47,52-71,74-77,163-164H2,1-17H3,(H2,165,208)(H2,166,209)(H2,167,210)(H2,168,223)(H,171,176)(H,174,226)(H,175,227)(H,177,224)(H,178,232)(H,179,211)(H,180,212)(H,181,249)(H,182,225)(H,183,230)(H,184,238)(H,185,246)(H,186,234)(H,187,236)(H,188,240)(H,189,239)(H,190,244)(H,191,237)(H,192,228)(H,193,229)(H,194,233)(H,195,245)(H,196,248)(H,197,247)(H,198,235)(H,199,241)(H,200,242)(H,201,250)(H,202,231)(H,203,243)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H,221,222)(H4,169,170,172)/t82-,83-,84-,85-,86-,87+,88+,97-,99-,100?,101-,102-,103-,104-,105-,106-,107?,108?,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,129-,130-,131-,132-,133-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.350	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183648 (CHEMBL3822888) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C158H240N40O46/c1-20-24-46-97(178-137(224)100(51-53-120(207)208)179-145(232)111(67-122(211)212)190-152(239)115(75-200)193-142(229)105(60-88-39-28-25-29-40-88)186-151(238)114(74-199)175-119(206)73-170-134(221)110(66-121(209)210)174-118(205)72-169-133(220)94(160)64-92-71-166-76-171-92)135(222)184-107(62-90-43-32-27-33-44-90)150(237)198-129(87(19)202)157(244)196-127(83(15)23-4)155(242)191-103(58-79(9)10)141(228)189-113(69-124(215)216)146(233)182-102(57-78(7)8)140(227)181-101(56-77(5)6)139(226)173-84(16)131(218)172-85(17)132(219)177-98(49-38-55-167-158(164)165)136(223)188-112(68-123(213)214)147(234)185-106(61-89-41-30-26-31-42-89)149(236)195-126(82(14)22-3)154(241)192-109(65-117(162)204)144(231)187-108(63-91-70-168-95-47-35-34-45-93(91)95)143(230)183-104(59-80(11)12)148(235)194-125(81(13)21-2)153(240)180-99(50-52-116(161)203)138(225)197-128(86(18)201)156(243)176-96(130(163)217)48-36-37-54-159/h25-35,39-45,47,70-71,76-87,94,96-115,125-129,168,199-202H,20-24,36-38,46,48-69,72-75,159-160H2,1-19H3,(H2,161,203)(H2,162,204)(H2,163,217)(H,166,171)(H,169,220)(H,170,221)(H,172,218)(H,173,226)(H,174,205)(H,175,206)(H,176,243)(H,177,219)(H,178,224)(H,179,232)(H,180,240)(H,181,227)(H,182,233)(H,183,230)(H,184,222)(H,185,234)(H,186,238)(H,187,231)(H,188,223)(H,189,228)(H,190,239)(H,191,242)(H,192,241)(H,193,229)(H,194,235)(H,195,236)(H,196,244)(H,197,225)(H,198,237)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H4,164,165,167)/t81-,82-,83-,84-,85-,86+,87+,94-,96-,97?,98-,99-,100-,101-,102-,103-,104-,105-,106-,107+,108-,109-,110-,111-,112-,113-,114-,115-,125-,126-,127-,128-,129-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0800	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183649 (CHEMBL3823722) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C161H238N40O46/c1-18-22-49-100(181-140(227)103(54-56-123(210)211)182-148(235)114(70-125(214)215)193-155(242)118(78-203)196-145(232)108(63-91-42-29-24-30-43-91)189-154(241)117(77-202)178-122(209)76-173-137(224)113(69-124(212)213)177-121(208)75-172-136(223)97(163)67-95-74-169-79-174-95)138(225)186-110(65-93-46-33-26-34-47-93)153(240)201-132(89(17)205)160(247)199-130(85(13)21-4)158(245)194-105(60-81(7)8)143(230)192-116(72-127(218)219)150(237)187-107(62-90-40-27-23-28-41-90)144(231)184-104(59-80(5)6)142(229)176-86(14)134(221)175-87(15)135(222)180-101(52-39-58-170-161(167)168)139(226)191-115(71-126(216)217)149(236)188-109(64-92-44-31-25-32-45-92)152(239)198-129(84(12)20-3)157(244)195-112(68-120(165)207)147(234)190-111(66-94-73-171-98-50-36-35-48-96(94)98)146(233)185-106(61-82(9)10)151(238)197-128(83(11)19-2)156(243)183-102(53-55-119(164)206)141(228)200-131(88(16)204)159(246)179-99(133(166)220)51-37-38-57-162/h23-36,40-48,50,73-74,79-89,97,99-118,128-132,171,202-205H,18-22,37-39,49,51-72,75-78,162-163H2,1-17H3,(H2,164,206)(H2,165,207)(H2,166,220)(H,169,174)(H,172,223)(H,173,224)(H,175,221)(H,176,229)(H,177,208)(H,178,209)(H,179,246)(H,180,222)(H,181,227)(H,182,235)(H,183,243)(H,184,231)(H,185,233)(H,186,225)(H,187,237)(H,188,236)(H,189,241)(H,190,234)(H,191,226)(H,192,230)(H,193,242)(H,194,245)(H,195,244)(H,196,232)(H,197,238)(H,198,239)(H,199,247)(H,200,228)(H,201,240)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H,218,219)(H4,167,168,170)/t83-,84-,85-,86-,87-,88+,89+,97-,99-,100?,101-,102-,103-,104-,105-,106-,107-,108-,109-,110+,111-,112-,113-,114-,115-,116-,117-,118-,128-,129-,130-,131-,132-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0900	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183650 (CHEMBL3823421) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C161H238N40O47/c1-18-22-44-100(181-140(228)103(53-55-123(211)212)182-148(236)114(69-125(215)216)193-155(243)118(77-203)196-145(233)107(61-89-37-26-23-27-38-89)189-154(242)117(76-202)178-122(210)75-173-137(225)113(68-124(213)214)177-121(209)74-172-136(224)97(163)66-94-73-169-78-174-94)138(226)186-110(63-91-41-30-25-31-42-91)153(241)201-132(88(17)205)160(248)199-130(84(13)21-4)158(246)194-105(59-80(7)8)143(231)192-116(71-127(219)220)150(238)187-108(64-92-48-50-95(206)51-49-92)144(232)184-104(58-79(5)6)142(230)176-85(14)134(222)175-86(15)135(223)180-101(47-36-57-170-161(167)168)139(227)191-115(70-126(217)218)149(237)188-109(62-90-39-28-24-29-40-90)152(240)198-129(83(12)20-3)157(245)195-112(67-120(165)208)147(235)190-111(65-93-72-171-98-45-33-32-43-96(93)98)146(234)185-106(60-81(9)10)151(239)197-128(82(11)19-2)156(244)183-102(52-54-119(164)207)141(229)200-131(87(16)204)159(247)179-99(133(166)221)46-34-35-56-162/h23-33,37-43,45,48-51,72-73,78-88,97,99-118,128-132,171,202-206H,18-22,34-36,44,46-47,52-71,74-77,162-163H2,1-17H3,(H2,164,207)(H2,165,208)(H2,166,221)(H,169,174)(H,172,224)(H,173,225)(H,175,222)(H,176,230)(H,177,209)(H,178,210)(H,179,247)(H,180,223)(H,181,228)(H,182,236)(H,183,244)(H,184,232)(H,185,234)(H,186,226)(H,187,238)(H,188,237)(H,189,242)(H,190,235)(H,191,227)(H,192,231)(H,193,243)(H,194,246)(H,195,245)(H,196,233)(H,197,239)(H,198,240)(H,199,248)(H,200,229)(H,201,241)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H,219,220)(H4,167,168,170)/t82-,83-,84-,85-,86-,87+,88+,97-,99-,100?,101-,102-,103-,104-,105-,106-,107-,108-,109-,110+,111-,112-,113-,114-,115-,116-,117-,118-,128-,129-,130-,131-,132-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0700	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183651 (CHEMBL3824241) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C156H238N40O46S/c1-20-24-43-95(176-135(222)98(48-50-118(205)206)177-143(230)109(65-120(209)210)188-150(237)113(73-198)191-140(227)103(58-86-37-27-25-28-38-86)183-149(236)112(72-197)173-117(204)71-168-132(219)108(64-119(207)208)172-116(203)70-167-131(218)92(158)61-89-69-164-74-169-89)133(220)185-106(62-90-41-36-53-243-90)148(235)196-127(85(19)200)155(242)194-125(81(15)23-4)153(240)189-101(56-77(9)10)139(226)187-111(67-122(213)214)144(231)180-100(55-76(7)8)138(225)179-99(54-75(5)6)137(224)171-82(16)129(216)170-83(17)130(217)175-96(46-35-52-165-156(162)163)134(221)186-110(66-121(211)212)145(232)182-104(59-87-39-29-26-30-40-87)147(234)193-124(80(14)22-3)152(239)190-107(63-115(160)202)142(229)184-105(60-88-68-166-93-44-32-31-42-91(88)93)141(228)181-102(57-78(11)12)146(233)192-123(79(13)21-2)151(238)178-97(47-49-114(159)201)136(223)195-126(84(18)199)154(241)174-94(128(161)215)45-33-34-51-157/h25-32,36-42,44,53,68-69,74-85,92,94-113,123-127,166,197-200H,20-24,33-35,43,45-52,54-67,70-73,157-158H2,1-19H3,(H2,159,201)(H2,160,202)(H2,161,215)(H,164,169)(H,167,218)(H,168,219)(H,170,216)(H,171,224)(H,172,203)(H,173,204)(H,174,241)(H,175,217)(H,176,222)(H,177,230)(H,178,238)(H,179,225)(H,180,231)(H,181,228)(H,182,232)(H,183,236)(H,184,229)(H,185,220)(H,186,221)(H,187,226)(H,188,237)(H,189,240)(H,190,239)(H,191,227)(H,192,233)(H,193,234)(H,194,242)(H,195,223)(H,196,235)(H,205,206)(H,207,208)(H,209,210)(H,211,212)(H,213,214)(H4,162,163,165)/t79-,80-,81-,82-,83-,84+,85+,92-,94-,95?,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106+,107-,108-,109-,110-,111-,112-,113-,123-,124-,125-,126-,127-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0800	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183652 (CHEMBL3823291) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C159H236N40O46S/c1-18-22-46-98(179-138(225)101(51-53-121(208)209)180-146(233)112(68-123(212)213)191-153(240)116(76-201)194-143(230)106(61-89-40-28-24-29-41-89)186-152(239)115(75-200)176-120(207)74-171-135(222)111(67-122(210)211)175-119(206)73-170-134(221)95(161)64-92-72-167-77-172-92)136(223)188-109(65-93-44-37-56-246-93)151(238)199-130(87(17)203)158(245)197-128(83(13)21-4)156(243)192-103(58-79(7)8)141(228)190-114(70-125(216)217)148(235)184-105(60-88-38-26-23-27-39-88)142(229)182-102(57-78(5)6)140(227)174-84(14)132(219)173-85(15)133(220)178-99(49-36-55-168-159(165)166)137(224)189-113(69-124(214)215)147(234)185-107(62-90-42-30-25-31-43-90)150(237)196-127(82(12)20-3)155(242)193-110(66-118(163)205)145(232)187-108(63-91-71-169-96-47-33-32-45-94(91)96)144(231)183-104(59-80(9)10)149(236)195-126(81(11)19-2)154(241)181-100(50-52-117(162)204)139(226)198-129(86(16)202)157(244)177-97(131(164)218)48-34-35-54-160/h23-33,37-45,47,56,71-72,77-87,95,97-116,126-130,169,200-203H,18-22,34-36,46,48-55,57-70,73-76,160-161H2,1-17H3,(H2,162,204)(H2,163,205)(H2,164,218)(H,167,172)(H,170,221)(H,171,222)(H,173,219)(H,174,227)(H,175,206)(H,176,207)(H,177,244)(H,178,220)(H,179,225)(H,180,233)(H,181,241)(H,182,229)(H,183,231)(H,184,235)(H,185,234)(H,186,239)(H,187,232)(H,188,223)(H,189,224)(H,190,228)(H,191,240)(H,192,243)(H,193,242)(H,194,230)(H,195,236)(H,196,237)(H,197,245)(H,198,226)(H,199,238)(H,208,209)(H,210,211)(H,212,213)(H,214,215)(H,216,217)(H4,165,166,168)/t81-,82-,83-,84-,85-,86+,87+,95-,97-,98?,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109+,110-,111-,112-,113-,114-,115-,116-,126-,127-,128-,129-,130-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0800	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183653 (CHEMBL3823334) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C159H236N40O47S/c1-18-22-41-98(179-138(226)101(50-52-121(209)210)180-146(234)112(67-123(213)214)191-153(241)116(75-201)194-143(231)105(59-87-35-25-23-26-36-87)186-152(240)115(74-200)176-120(208)73-171-135(223)111(66-122(211)212)175-119(207)72-170-134(222)95(161)63-91-71-167-76-172-91)136(224)188-109(64-93-39-34-55-247-93)151(239)199-130(86(17)203)158(246)197-128(82(13)21-4)156(244)192-103(57-78(7)8)141(229)190-114(69-125(217)218)148(236)184-106(61-89-45-47-92(204)48-46-89)142(230)182-102(56-77(5)6)140(228)174-83(14)132(220)173-84(15)133(221)178-99(44-33-54-168-159(165)166)137(225)189-113(68-124(215)216)147(235)185-107(60-88-37-27-24-28-38-88)150(238)196-127(81(12)20-3)155(243)193-110(65-118(163)206)145(233)187-108(62-90-70-169-96-42-30-29-40-94(90)96)144(232)183-104(58-79(9)10)149(237)195-126(80(11)19-2)154(242)181-100(49-51-117(162)205)139(227)198-129(85(16)202)157(245)177-97(131(164)219)43-31-32-53-160/h23-30,34-40,42,45-48,55,70-71,76-86,95,97-116,126-130,169,200-204H,18-22,31-33,41,43-44,49-54,56-69,72-75,160-161H2,1-17H3,(H2,162,205)(H2,163,206)(H2,164,219)(H,167,172)(H,170,222)(H,171,223)(H,173,220)(H,174,228)(H,175,207)(H,176,208)(H,177,245)(H,178,221)(H,179,226)(H,180,234)(H,181,242)(H,182,230)(H,183,232)(H,184,236)(H,185,235)(H,186,240)(H,187,233)(H,188,224)(H,189,225)(H,190,229)(H,191,241)(H,192,244)(H,193,243)(H,194,231)(H,195,237)(H,196,238)(H,197,246)(H,198,227)(H,199,239)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H4,165,166,168)/t80-,81-,82-,83-,84-,85+,86+,95-,97-,98?,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109+,110-,111-,112-,113-,114-,115-,116-,126-,127-,128-,129-,130-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0700	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183654 (CHEMBL3823835) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(N)=O |r| Show InChI InChI=1S/C159H242N40O47/c1-20-24-46-97(177-137(225)100(51-53-120(209)210)178-145(233)111(67-122(213)214)190-152(240)115(75-201)193-142(230)105(60-88-39-28-25-29-40-88)186-151(239)114(74-200)175-119(208)73-171-134(222)110(66-121(211)212)174-118(207)72-170-133(221)94(161)64-92-71-167-76-172-92)135(223)184-107(62-90-43-32-27-33-44-90)150(238)199-130(87(19)204)158(246)196-127(83(15)23-4)155(243)191-103(58-79(9)10)141(229)189-113(69-124(217)218)146(234)182-102(57-78(7)8)140(228)181-101(56-77(5)6)139(227)173-84(16)132(220)197-128(85(17)202)157(245)179-98(49-38-55-168-159(165)166)136(224)188-112(68-123(215)216)147(235)185-106(61-89-41-30-26-31-42-89)149(237)195-126(82(14)22-3)154(242)192-109(65-117(163)206)144(232)187-108(63-91-70-169-95-47-35-34-45-93(91)95)143(231)183-104(59-80(11)12)148(236)194-125(81(13)21-2)153(241)180-99(50-52-116(162)205)138(226)198-129(86(18)203)156(244)176-96(131(164)219)48-36-37-54-160/h25-35,39-45,47,70-71,76-87,94,96-115,125-130,169,200-204H,20-24,36-38,46,48-69,72-75,160-161H2,1-19H3,(H2,162,205)(H2,163,206)(H2,164,219)(H,167,172)(H,170,221)(H,171,222)(H,173,227)(H,174,207)(H,175,208)(H,176,244)(H,177,225)(H,178,233)(H,179,245)(H,180,241)(H,181,228)(H,182,234)(H,183,231)(H,184,223)(H,185,235)(H,186,239)(H,187,232)(H,188,224)(H,189,229)(H,190,240)(H,191,243)(H,192,242)(H,193,230)(H,194,236)(H,195,237)(H,196,246)(H,197,220)(H,198,226)(H,199,238)(H,209,210)(H,211,212)(H,213,214)(H,215,216)(H,217,218)(H4,165,166,168)/t81-,82-,83-,84-,85+,86+,87+,94-,96-,97?,98-,99-,100-,101-,102-,103-,104-,105-,106-,107+,108-,109-,110-,111-,112-,113-,114-,115-,125-,126-,127-,128-,129-,130-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0400	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183655 (CHEMBL3823133) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C172H262N42O53/c1-23-28-50-103(190-147(242)107(55-57-128(224)225)191-156(251)118(71-130(228)229)203-163(258)123(80-216)207-153(248)112(64-95-43-32-29-33-44-95)199-162(257)122(79-215)188-127(223)78-183-144(239)117(70-129(226)227)187-126(222)77-182-143(238)101(174)68-99-76-179-81-184-99)145(240)197-114(66-97-47-36-31-37-48-97)161(256)213-140(94(22)219)170(265)211-136(88(16)26-4)166(261)204-110(62-84(10)11)152(247)202-120(73-132(232)233)157(252)195-109(61-83(8)9)151(246)194-108(60-82(6)7)150(245)186-90(18)141(236)185-91(19)142(237)189-105(53-42-59-180-172(177)178)146(241)201-119(72-131(230)231)158(253)198-113(65-96-45-34-30-35-46-96)160(255)210-135(87(15)25-3)165(260)205-116(69-125(176)221)155(250)200-115(67-98-75-181-102-51-39-38-49-100(98)102)154(249)196-111(63-85(12)13)159(254)209-134(86(14)24-2)164(259)193-106(54-56-124(175)220)149(244)212-138(92(20)217)168(263)192-104(52-40-41-58-173)148(243)208-137(89(17)27-5)167(262)214-139(93(21)218)169(264)206-121(171(266)267)74-133(234)235/h29-39,43-49,51,75-76,81-94,101,103-123,134-140,181,215-219H,23-28,40-42,50,52-74,77-80,173-174H2,1-22H3,(H2,175,220)(H2,176,221)(H,179,184)(H,182,238)(H,183,239)(H,185,236)(H,186,245)(H,187,222)(H,188,223)(H,189,237)(H,190,242)(H,191,251)(H,192,263)(H,193,259)(H,194,246)(H,195,252)(H,196,249)(H,197,240)(H,198,253)(H,199,257)(H,200,250)(H,201,241)(H,202,247)(H,203,258)(H,204,261)(H,205,260)(H,206,264)(H,207,248)(H,208,243)(H,209,254)(H,210,255)(H,211,265)(H,212,244)(H,213,256)(H,214,262)(H,224,225)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,266,267)(H4,177,178,180)/t86-,87-,88-,89-,90-,91-,92+,93+,94+,101-,103?,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114+,115-,116-,117-,118-,119-,120-,121-,122-,123-,134-,135-,136-,137-,138-,139-,140-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183657 (CHEMBL3823541) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C172H263N43O52/c1-23-28-50-103(191-148(244)107(55-57-128(225)226)192-157(253)119(72-131(231)232)205-164(260)123(80-217)208-154(250)113(64-95-43-32-29-33-44-95)201-163(259)122(79-216)189-127(224)78-184-145(241)118(71-130(229)230)188-126(223)77-183-144(240)101(174)68-99-76-180-81-185-99)146(242)199-115(66-97-47-36-31-37-48-97)162(258)214-140(94(22)220)171(267)212-136(88(16)26-4)167(263)206-111(62-84(10)11)153(249)204-121(74-133(235)236)158(254)197-110(61-83(8)9)152(248)196-109(60-82(6)7)151(247)187-90(18)142(238)186-91(19)143(239)190-105(53-42-59-181-172(178)179)147(243)203-120(73-132(233)234)159(255)200-114(65-96-45-34-30-35-46-96)161(257)211-135(87(15)25-3)166(262)207-117(69-125(176)222)156(252)202-116(67-98-75-182-102-51-39-38-49-100(98)102)155(251)198-112(63-85(12)13)160(256)210-134(86(14)24-2)165(261)194-106(54-56-124(175)221)150(246)213-138(92(20)218)169(265)193-104(52-40-41-58-173)149(245)209-137(89(17)27-5)168(264)215-139(93(21)219)170(266)195-108(141(177)237)70-129(227)228/h29-39,43-49,51,75-76,81-94,101,103-123,134-140,182,216-220H,23-28,40-42,50,52-74,77-80,173-174H2,1-22H3,(H2,175,221)(H2,176,222)(H2,177,237)(H,180,185)(H,183,240)(H,184,241)(H,186,238)(H,187,247)(H,188,223)(H,189,224)(H,190,239)(H,191,244)(H,192,253)(H,193,265)(H,194,261)(H,195,266)(H,196,248)(H,197,254)(H,198,251)(H,199,242)(H,200,255)(H,201,259)(H,202,252)(H,203,243)(H,204,249)(H,205,260)(H,206,263)(H,207,262)(H,208,250)(H,209,245)(H,210,256)(H,211,257)(H,212,267)(H,213,246)(H,214,258)(H,215,264)(H,225,226)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H4,178,179,181)/t86-,87-,88-,89-,90-,91-,92+,93+,94+,101-,103?,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115+,116-,117-,118-,119-,120-,121-,122-,123-,134-,135-,136-,137-,138-,139-,140-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183658 (CHEMBL3822459) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(O)=O |r| Show InChI InChI=1S/C175H260N42O53/c1-21-26-53-106(193-150(245)110(58-60-131(227)228)194-159(254)121(74-133(231)232)206-166(261)126(83-219)210-156(251)115(67-98-46-33-28-34-47-98)202-165(260)125(82-218)191-130(226)81-186-147(242)120(73-132(229)230)190-129(225)80-185-146(241)104(177)71-102-79-182-84-187-102)148(243)199-117(69-100-50-37-30-38-51-100)164(259)216-143(96(20)222)173(268)214-139(90(14)24-4)169(264)207-112(64-86(8)9)154(249)205-123(76-135(235)236)161(256)200-114(66-97-44-31-27-32-45-97)155(250)197-111(63-85(6)7)153(248)189-92(16)144(239)188-93(17)145(240)192-108(56-43-62-183-175(180)181)149(244)204-122(75-134(233)234)160(255)201-116(68-99-48-35-29-36-49-99)163(258)213-138(89(13)23-3)168(263)208-119(72-128(179)224)158(253)203-118(70-101-78-184-105-54-40-39-52-103(101)105)157(252)198-113(65-87(10)11)162(257)212-137(88(12)22-2)167(262)196-109(57-59-127(178)223)152(247)215-141(94(18)220)171(266)195-107(55-41-42-61-176)151(246)211-140(91(15)25-5)170(265)217-142(95(19)221)172(267)209-124(174(269)270)77-136(237)238/h27-40,44-52,54,78-79,84-96,104,106-126,137-143,184,218-222H,21-26,41-43,53,55-77,80-83,176-177H2,1-20H3,(H2,178,223)(H2,179,224)(H,182,187)(H,185,241)(H,186,242)(H,188,239)(H,189,248)(H,190,225)(H,191,226)(H,192,240)(H,193,245)(H,194,254)(H,195,266)(H,196,262)(H,197,250)(H,198,252)(H,199,243)(H,200,256)(H,201,255)(H,202,260)(H,203,253)(H,204,244)(H,205,249)(H,206,261)(H,207,264)(H,208,263)(H,209,267)(H,210,251)(H,211,246)(H,212,257)(H,213,258)(H,214,268)(H,215,247)(H,216,259)(H,217,265)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H,235,236)(H,237,238)(H,269,270)(H4,180,181,183)/t88-,89-,90-,91-,92-,93-,94+,95+,96+,104-,106?,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117+,118-,119-,120-,121-,122-,123-,124-,125-,126-,137-,138-,139-,140-,141-,142-,143-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0600	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183659 (CHEMBL3824232) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C175H261N43O52/c1-21-26-53-106(194-151(247)110(58-60-131(228)229)195-160(256)122(75-134(234)235)208-167(263)126(83-220)211-157(253)116(67-98-46-33-28-34-47-98)204-166(262)125(82-219)192-130(227)81-187-148(244)121(74-133(232)233)191-129(226)80-186-147(243)104(177)71-102-79-183-84-188-102)149(245)201-118(69-100-50-37-30-38-51-100)165(261)217-143(96(20)223)174(270)215-139(90(14)24-4)170(266)209-113(64-86(8)9)155(251)207-124(77-136(238)239)162(258)202-115(66-97-44-31-27-32-45-97)156(252)199-112(63-85(6)7)154(250)190-92(16)145(241)189-93(17)146(242)193-108(56-43-62-184-175(181)182)150(246)206-123(76-135(236)237)161(257)203-117(68-99-48-35-29-36-49-99)164(260)214-138(89(13)23-3)169(265)210-120(72-128(179)225)159(255)205-119(70-101-78-185-105-54-40-39-52-103(101)105)158(254)200-114(65-87(10)11)163(259)213-137(88(12)22-2)168(264)197-109(57-59-127(178)224)153(249)216-141(94(18)221)172(268)196-107(55-41-42-61-176)152(248)212-140(91(15)25-5)171(267)218-142(95(19)222)173(269)198-111(144(180)240)73-132(230)231/h27-40,44-52,54,78-79,84-96,104,106-126,137-143,185,219-223H,21-26,41-43,53,55-77,80-83,176-177H2,1-20H3,(H2,178,224)(H2,179,225)(H2,180,240)(H,183,188)(H,186,243)(H,187,244)(H,189,241)(H,190,250)(H,191,226)(H,192,227)(H,193,242)(H,194,247)(H,195,256)(H,196,268)(H,197,264)(H,198,269)(H,199,252)(H,200,254)(H,201,245)(H,202,258)(H,203,257)(H,204,262)(H,205,255)(H,206,246)(H,207,251)(H,208,263)(H,209,266)(H,210,265)(H,211,253)(H,212,248)(H,213,259)(H,214,260)(H,215,270)(H,216,249)(H,217,261)(H,218,267)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H,238,239)(H4,181,182,184)/t88-,89-,90-,91-,92-,93-,94+,95+,96+,104-,106?,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118+,119-,120-,121-,122-,123-,124-,125-,126-,137-,138-,139-,140-,141-,142-,143-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0600	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183660 (CHEMBL3824079) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccs1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C173H259N43O52S/c1-21-26-50-104(192-149(245)108(55-57-129(226)227)193-158(254)120(73-132(232)233)206-165(261)124(81-218)209-155(251)114(65-96-44-32-28-33-45-96)201-164(260)123(80-217)190-128(225)79-185-146(242)119(72-131(230)231)189-127(224)78-184-145(241)102(175)68-99-77-181-82-186-99)147(243)203-117(69-100-48-41-60-269-100)163(259)215-141(94(20)221)172(268)213-137(88(14)24-4)168(264)207-111(62-84(8)9)153(249)205-122(75-134(236)237)160(256)199-113(64-95-42-30-27-31-43-95)154(250)197-110(61-83(6)7)152(248)188-90(16)143(239)187-91(17)144(240)191-106(53-40-59-182-173(179)180)148(244)204-121(74-133(234)235)159(255)200-115(66-97-46-34-29-35-47-97)162(258)212-136(87(13)23-3)167(263)208-118(70-126(177)223)157(253)202-116(67-98-76-183-103-51-37-36-49-101(98)103)156(252)198-112(63-85(10)11)161(257)211-135(86(12)22-2)166(262)195-107(54-56-125(176)222)151(247)214-139(92(18)219)170(266)194-105(52-38-39-58-174)150(246)210-138(89(15)25-5)169(265)216-140(93(19)220)171(267)196-109(142(178)238)71-130(228)229/h27-37,41-49,51,60,76-77,82-94,102,104-124,135-141,183,217-221H,21-26,38-40,50,52-59,61-75,78-81,174-175H2,1-20H3,(H2,176,222)(H2,177,223)(H2,178,238)(H,181,186)(H,184,241)(H,185,242)(H,187,239)(H,188,248)(H,189,224)(H,190,225)(H,191,240)(H,192,245)(H,193,254)(H,194,266)(H,195,262)(H,196,267)(H,197,250)(H,198,252)(H,199,256)(H,200,255)(H,201,260)(H,202,253)(H,203,243)(H,204,244)(H,205,249)(H,206,261)(H,207,264)(H,208,263)(H,209,251)(H,210,246)(H,211,257)(H,212,258)(H,213,268)(H,214,247)(H,215,259)(H,216,265)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H4,179,180,182)/t86-,87-,88-,89-,90-,91-,92+,93+,94+,102-,104?,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117+,118-,119-,120-,121-,122-,123-,124-,135-,136-,137-,138-,139-,140-,141-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0700	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair
Glucagon-like peptide 2 receptor (Homo sapiens (Human))	BDBM50183661 (CHEMBL3823043) Show SMILES CCCCC(NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@H](Cc1cccc(Cl)c1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C172H262ClN43O52/c1-23-28-48-103(192-148(245)107(53-55-128(226)227)193-157(254)119(71-131(232)233)206-164(261)123(79-218)209-154(251)113(63-94-41-31-29-32-42-94)202-163(260)122(78-217)190-127(225)77-185-145(242)118(70-130(230)231)189-126(224)76-184-144(241)101(175)67-99-75-181-80-186-99)146(243)200-115(65-96-45-39-46-98(173)62-96)162(259)215-140(93(22)221)171(268)213-136(87(16)26-4)167(264)207-111(60-83(10)11)153(250)205-121(73-133(236)237)158(255)198-110(59-82(8)9)152(249)197-109(58-81(6)7)151(248)188-89(18)142(239)187-90(19)143(240)191-105(51-40-57-182-172(179)180)147(244)204-120(72-132(234)235)159(256)201-114(64-95-43-33-30-34-44-95)161(258)212-135(86(15)25-3)166(263)208-117(68-125(177)223)156(253)203-116(66-97-74-183-102-49-36-35-47-100(97)102)155(252)199-112(61-84(12)13)160(257)211-134(85(14)24-2)165(262)195-106(52-54-124(176)222)150(247)214-138(91(20)219)169(266)194-104(50-37-38-56-174)149(246)210-137(88(17)27-5)168(265)216-139(92(21)220)170(267)196-108(141(178)238)69-129(228)229/h29-36,39,41-47,49,62,74-75,80-93,101,103-123,134-140,183,217-221H,23-28,37-38,40,48,50-61,63-73,76-79,174-175H2,1-22H3,(H2,176,222)(H2,177,223)(H2,178,238)(H,181,186)(H,184,241)(H,185,242)(H,187,239)(H,188,248)(H,189,224)(H,190,225)(H,191,240)(H,192,245)(H,193,254)(H,194,266)(H,195,262)(H,196,267)(H,197,249)(H,198,255)(H,199,252)(H,200,243)(H,201,256)(H,202,260)(H,203,253)(H,204,244)(H,205,250)(H,206,261)(H,207,264)(H,208,263)(H,209,251)(H,210,246)(H,211,257)(H,212,258)(H,213,268)(H,214,247)(H,215,259)(H,216,265)(H,226,227)(H,228,229)(H,230,231)(H,232,233)(H,234,235)(H,236,237)(H4,179,180,182)/t85-,86-,87-,88-,89-,90-,91+,92+,93+,101-,103?,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115+,116-,117-,118-,119-,120-,121-,122-,123-,134-,135-,136-,137-,138-,139-,140-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0900	n/a	n/a	n/a	n/a
Ferring Research Institute Inc. Curated by ChEMBL					Assay Description Agonist activity at human GLP2R expressed in HEK293 cells after 5 hrs by luciferase reporter gene assay				J Med Chem 59: 3129-39 (2016) Article DOI: 10.1021/acs.jmedchem.5b01909 BindingDB Entry DOI: 10.7270/Q23R0VT7
					More data for this Ligand-Target Pair

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