Compile Data Set for Download or QSAR

Found 166 hits with Last Name = 'phelan' and Initial = 'km'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cKit by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cKit by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT4 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175237 (CHEMBL199528 | N-butyl-N-methyl-3-phenyl-1H-thieno...) Show SMILES CCCCN(C)C(=O)c1cc2c(n[nH]c2s1)-c1ccccc1 Show InChI InChI=1S/C17H19N3OS/c1-3-4-10-20(2)17(21)14-11-13-15(18-19-16(13)22-14)12-8-6-5-7-9-12/h5-9,11H,3-4,10H2,1-2H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188283 (6-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccsc3)c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-17-16(10-14)11-18-19(21-22-20(17)18)15-4-9-25-13-15/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175239 (CHEMBL199755 | N-cyclohexyl-3-phenyl-1H-thieno[2,3...) Show SMILES O=C(NC1CCCCC1)c1cc2c(n[nH]c2s1)-c1ccccc1 Show InChI InChI=1S/C18H19N3OS/c22-17(19-13-9-5-2-6-10-13)15-11-14-16(20-21-18(14)23-15)12-7-3-1-4-8-12/h1,3-4,7-8,11,13H,2,5-6,9-10H2,(H,19,22)(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175247 (CHEMBL200499 | N-benzyl-3-phenyl-1H-thieno[2,3-c]p...) Show SMILES O=C(NCc1ccccc1)c1cc2c(n[nH]c2s1)-c1ccccc1 Show InChI InChI=1S/C19H15N3OS/c23-18(20-12-13-7-3-1-4-8-13)16-11-15-17(21-22-19(15)24-16)14-9-5-2-6-10-14/h1-11H,12H2,(H,20,23)(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188281 (4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroi...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c(n[nH]c-34)-c3ccc(O)cc3)c2)CC1 Show InChI InChI=1S/C22H24N4O/c1-25-8-10-26(11-9-25)14-15-2-7-19-17(12-15)13-20-21(23-24-22(19)20)16-3-5-18(27)6-4-16/h2-7,12,27H,8-11,13-14H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175241 (CHEMBL199383 | N-(4-methoxybenzyl)-3-phenyl-1H-thi...) Show SMILES COc1ccc(CNC(=O)c2cc3c(n[nH]c3s2)-c2ccccc2)cc1 Show InChI InChI=1S/C20H17N3O2S/c1-25-15-9-7-13(8-10-15)12-21-19(24)17-11-16-18(22-23-20(16)26-17)14-5-3-2-4-6-14/h2-11H,12H2,1H3,(H,21,24)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188290 (7-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...) Show SMILES CN1CCN(Cc2ccc3Cc4c([nH]nc4-c4ccccc4)-c3c2)CC1 Show InChI InChI=1S/C22H24N4/c1-25-9-11-26(12-10-25)15-16-7-8-18-14-20-21(17-5-3-2-4-6-17)23-24-22(20)19(18)13-16/h2-8,13H,9-12,14-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	601	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT1 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188275 (6-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3[nH]nc4-c3ccccc3)c2)CC1 Show InChI InChI=1S/C22H24N4/c1-25-9-11-26(12-10-25)15-16-7-8-19-18(13-16)14-20-21(23-24-22(19)20)17-5-3-2-4-6-17/h2-8,13H,9-12,14-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188292 (3-(thiophen-2-yl)-1,4-dihydroindeno[1,2-c]pyrazole...) Show SMILES C1c2ccccc2-c2n[nH]c(c12)-c1cccs1 Show InChI InChI=1S/C14H10N2S/c1-2-5-10-9(4-1)8-11-13(10)15-16-14(11)12-6-3-7-17-12/h1-7H,8H2,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT1 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188271 (6-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-2-y...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3cccs3)c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-6-8-24(9-7-23)13-14-4-5-16-15(11-14)12-17-19(16)21-22-20(17)18-3-2-10-25-18/h2-5,10-11H,6-9,12-13H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188284 (3-phenyl-1,4-dihydroindeno[1,2-c]pyrazole | CHEMBL...) Show SMILES C1c2ccccc2-c2[nH]nc(c12)-c1ccccc1 Show InChI InChI=1S/C16H12N2/c1-2-6-11(7-3-1)15-14-10-12-8-4-5-9-13(12)16(14)18-17-15/h1-9H,10H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188269 (3-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1,4-d...) Show SMILES CN1CCN(Cc2ccc(cc2)-c2[nH]nc-3c2Cc2ccccc-32)CC1 Show InChI InChI=1S/C22H24N4/c1-25-10-12-26(13-11-25)15-16-6-8-17(9-7-16)21-20-14-18-4-2-3-5-19(18)22(20)24-23-21/h2-9H,10-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT4 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175234 (CHEMBL197923 | N-phenethyl-3-phenyl-1H-thieno[2,3-...) Show SMILES O=C(NCCc1ccccc1)c1cc2c(n[nH]c2s1)-c1ccccc1 Show InChI InChI=1S/C20H17N3OS/c24-19(21-12-11-14-7-3-1-4-8-14)17-13-16-18(22-23-20(16)25-17)15-9-5-2-6-10-15/h1-10,13H,11-12H2,(H,21,24)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188277 (6-((4-methylpiperazin-1-yl)methyl)-3-(thiazol-5-yl...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3cncs3)c2)CC1 Show InChI InChI=1S/C19H21N5S/c1-23-4-6-24(7-5-23)11-13-2-3-15-14(8-13)9-16-18(15)21-22-19(16)17-10-20-12-25-17/h2-3,8,10,12H,4-7,9,11H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188289 (3-(3-((4-methylpiperazin-1-yl)methyl)phenyl)-1,4-d...) Show SMILES CN1CCN(Cc2cccc(c2)-c2[nH]nc-3c2Cc2ccccc-32)CC1 Show InChI InChI=1S/C22H24N4/c1-25-9-11-26(12-10-25)15-16-5-4-7-18(13-16)21-20-14-17-6-2-3-8-19(17)22(20)24-23-21/h2-8,13H,9-12,14-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175232 ((4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]...) Show SMILES CN1CCN(CC1)C(=O)c1cc2c(n[nH]c2s1)-c1ccccc1 Show InChI InChI=1S/C17H18N4OS/c1-20-7-9-21(10-8-20)17(22)14-11-13-15(18-19-16(13)23-14)12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188273 (6-((4-methylpiperazin-1-yl)methyl)-3-(5-methylthio...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccc(C)s3)c2)CC1 Show InChI InChI=1S/C21H24N4S/c1-14-3-6-19(26-14)21-18-12-16-11-15(4-5-17(16)20(18)22-23-21)13-25-9-7-24(2)8-10-25/h3-6,11H,7-10,12-13H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175246 (3-methyl-4-(thiophene-2-carboxamido)-1H-thieno[2,3...) Show SMILES Cc1[nH]nc2sc(C(N)=O)c(NC(=O)c3cccs3)c12 Show InChI InChI=1S/C12H10N4O2S2/c1-5-7-8(14-11(18)6-3-2-4-19-6)9(10(13)17)20-12(7)16-15-5/h2-4H,1H3,(H2,13,17)(H,14,18)(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188274 (6-((4-methylpiperazin-1-yl)methyl)-3-(thiazol-4-yl...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3cscn3)c2)CC1 Show InChI InChI=1S/C19H21N5S/c1-23-4-6-24(7-5-23)10-13-2-3-15-14(8-13)9-16-18(15)21-22-19(16)17-11-25-12-20-17/h2-3,8,11-12H,4-7,9-10H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175235 (4-(2-chlorobenzamido)-3-methyl-1H-thieno[2,3-c]pyr...) Show SMILES Cc1[nH]nc2sc(C(N)=O)c(NC(=O)c3ccccc3Cl)c12 Show InChI InChI=1S/C14H11ClN4O2S/c1-6-9-10(11(12(16)20)22-14(9)19-18-6)17-13(21)7-4-2-3-5-8(7)15/h2-5H,1H3,(H2,16,20)(H,17,21)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50175250 (CHEMBL370199 | methyl 2-(5-carbamoyl-3-methyl-1H-t...) Show SMILES COC(=O)C(=O)Nc1c(sc2n[nH]c(C)c12)C(N)=O Show InChI InChI=1S/C10H10N4O4S/c1-3-4-5(12-8(16)10(17)18-2)6(7(11)15)19-9(4)14-13-3/h1-2H3,(H2,11,15)(H,12,16)(H,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Plk1				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50175245 (1-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyrazol-4-...) Show SMILES Cc1[nH]nc2sc(C(N)=O)c(NC(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C14H13N5O2S/c1-7-9-10(11(12(15)20)22-13(9)19-18-7)17-14(21)16-8-5-3-2-4-6-8/h2-6H,1H3,(H2,15,20)(H,18,19)(H2,16,17,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Akt1				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188279 (6-((4-methylpiperazin-1-yl)methyl)-3-(pyridin-3-yl...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c(n[nH]c-34)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C21H23N5/c1-25-7-9-26(10-8-25)14-15-4-5-18-17(11-15)12-19-20(23-24-21(18)19)16-3-2-6-22-13-16/h2-6,11,13H,7-10,12,14H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50175239 (CHEMBL199755 | N-cyclohexyl-3-phenyl-1H-thieno[2,3...) Show SMILES O=C(NC1CCCCC1)c1cc2c(n[nH]c2s1)-c1ccccc1 Show InChI InChI=1S/C18H19N3OS/c22-17(19-13-9-5-2-6-10-13)15-11-14-16(20-21-18(14)23-15)12-7-3-1-4-8-12/h1,3-4,7-8,11,13H,2,5-6,9-10H2,(H,19,22)(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against CDK2/Cyclin A				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175252 (3-methyl-4-(2-phenoxyacetamido)-1H-thieno[2,3-c]py...) Show SMILES Cc1[nH]nc2sc(C(N)=O)c(NC(=O)COc3ccccc3)c12 Show InChI InChI=1S/C15H14N4O3S/c1-8-11-12(13(14(16)21)23-15(11)19-18-8)17-10(20)7-22-9-5-3-2-4-6-9/h2-6H,7H2,1H3,(H2,16,21)(H,17,20)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50175239 (CHEMBL199755 | N-cyclohexyl-3-phenyl-1H-thieno[2,3...) Show SMILES O=C(NC1CCCCC1)c1cc2c(n[nH]c2s1)-c1ccccc1 Show InChI InChI=1S/C18H19N3OS/c22-17(19-13-9-5-2-6-10-13)15-11-14-16(20-21-18(14)23-15)12-7-3-1-4-8-12/h1,3-4,7-8,11,13H,2,5-6,9-10H2,(H,19,22)(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Plk1				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175243 (CHEMBL373001 | N-benzyl-3-methyl-1H-thieno[2,3-c]p...) Show SMILES Cc1n[nH]c2sc(cc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C14H13N3OS/c1-9-11-7-12(19-14(11)17-16-9)13(18)15-8-10-5-3-2-4-6-10/h2-7H,8H2,1H3,(H,15,18)(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188265 (6-((4-methylpiperazin-1-yl)methyl)-3-(4-methylthio...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3cc(C)cs3)c2)CC1 Show InChI InChI=1S/C21H24N4S/c1-14-9-19(26-13-14)21-18-11-16-10-15(3-4-17(16)20(18)22-23-21)12-25-7-5-24(2)6-8-25/h3-4,9-10,13H,5-8,11-12H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Homo sapiens (Human))	BDBM50175245 (1-(5-carbamoyl-3-methyl-1H-thieno[2,3-c]pyrazol-4-...) Show SMILES Cc1[nH]nc2sc(C(N)=O)c(NC(=O)Nc3ccccc3)c12 Show InChI InChI=1S/C14H13N5O2S/c1-7-9-10(11(12(15)20)22-13(9)19-18-7)17-14(21)16-8-5-3-2-4-6-8/h2-6H,1H3,(H2,15,20)(H,18,19)(H2,16,17,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Pak4				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188268 (5-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...) Show SMILES CN1CCN(Cc2cccc-3c2Cc2c-3[nH]nc2-c2ccccc2)CC1 Show InChI InChI=1S/C22H24N4/c1-25-10-12-26(13-11-25)15-17-8-5-9-18-19(17)14-20-21(23-24-22(18)20)16-6-3-2-4-7-16/h2-9H,10-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50175247 (CHEMBL200499 | N-benzyl-3-phenyl-1H-thieno[2,3-c]p...) Show SMILES O=C(NCc1ccccc1)c1cc2c(n[nH]c2s1)-c1ccccc1 Show InChI InChI=1S/C19H15N3OS/c23-18(20-12-13-7-3-1-4-8-13)16-11-15-17(21-22-19(15)24-16)14-9-5-2-6-10-14/h1-11H,12H2,(H,20,23)(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Akt1				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50175243 (CHEMBL373001 | N-benzyl-3-methyl-1H-thieno[2,3-c]p...) Show SMILES Cc1n[nH]c2sc(cc12)C(=O)NCc1ccccc1 Show InChI InChI=1S/C14H13N3OS/c1-9-11-7-12(19-14(11)17-16-9)13(18)15-8-10-5-3-2-4-6-10/h2-7H,8H2,1H3,(H,15,18)(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Plk1				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50175241 (CHEMBL199383 | N-(4-methoxybenzyl)-3-phenyl-1H-thi...) Show SMILES COc1ccc(CNC(=O)c2cc3c(n[nH]c3s2)-c2ccccc2)cc1 Show InChI InChI=1S/C20H17N3O2S/c1-25-15-9-7-13(8-10-15)12-21-19(24)17-11-16-18(22-23-20(16)26-17)14-5-3-2-4-6-14/h2-11H,12H2,1H3,(H,21,24)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against MK2				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50175251 (CHEMBL200796 | methyl 3-(phenylamino)-1H-thieno[2,...) Show SMILES COC(=O)c1cc2c(Nc3ccccc3)[nH]nc2s1 Show InChI InChI=1S/C13H11N3O2S/c1-18-13(17)10-7-9-11(15-16-12(9)19-10)14-8-5-3-2-4-6-8/h2-7H,1H3,(H2,14,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Akt1				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175249 (CHEMBL371242 | N-butyl-3-methyl-1H-thieno[2,3-c]py...) Show SMILES CCCCNC(=O)c1cc2c(C)n[nH]c2s1 Show InChI InChI=1S/C11H15N3OS/c1-3-4-5-12-10(15)9-6-8-7(2)13-14-11(8)16-9/h6H,3-5H2,1-2H3,(H,12,15)(H,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188287 (6-((4-methylpiperazin-1-yl)methyl)-3-(thiazol-2-yl...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c(n[nH]c-34)-c3nccs3)c2)CC1 Show InChI InChI=1S/C19H21N5S/c1-23-5-7-24(8-6-23)12-13-2-3-15-14(10-13)11-16-17(15)21-22-18(16)19-20-4-9-25-19/h2-4,9-10H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175250 (CHEMBL370199 | methyl 2-(5-carbamoyl-3-methyl-1H-t...) Show SMILES COC(=O)C(=O)Nc1c(sc2n[nH]c(C)c12)C(N)=O Show InChI InChI=1S/C10H10N4O4S/c1-3-4-5(12-8(16)10(17)18-2)6(7(11)15)19-9(4)14-13-3/h1-2H3,(H2,11,15)(H,12,16)(H,13,14)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Homo sapiens (Human))	BDBM50175234 (CHEMBL197923 | N-phenethyl-3-phenyl-1H-thieno[2,3-...) Show SMILES O=C(NCCc1ccccc1)c1cc2c(n[nH]c2s1)-c1ccccc1 Show InChI InChI=1S/C20H17N3OS/c24-19(21-12-11-14-7-3-1-4-8-14)17-13-16-18(22-23-20(16)25-17)15-9-5-2-6-10-15/h1-10,13H,11-12H2,(H,21,24)(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Plk1				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50175247 (CHEMBL200499 | N-benzyl-3-phenyl-1H-thieno[2,3-c]p...) Show SMILES O=C(NCc1ccccc1)c1cc2c(n[nH]c2s1)-c1ccccc1 Show InChI InChI=1S/C19H15N3OS/c23-18(20-12-13-7-3-1-4-8-13)16-11-15-17(21-22-19(15)24-16)14-9-5-2-6-10-14/h1-11H,12H2,(H,20,23)(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against MK2				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50175246 (3-methyl-4-(thiophene-2-carboxamido)-1H-thieno[2,3...) Show SMILES Cc1[nH]nc2sc(C(N)=O)c(NC(=O)c3cccs3)c12 Show InChI InChI=1S/C12H10N4O2S2/c1-5-7-8(14-11(18)6-3-2-4-19-6)9(10(13)17)20-12(7)16-15-5/h2-4H,1H3,(H2,13,17)(H,14,18)(H,15,16)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Akt1				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50175238 (3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide | ...) Show SMILES Cc1n[nH]c2sc(cc12)C(N)=O Show InChI InChI=1S/C7H7N3OS/c1-3-4-2-5(6(8)11)12-7(4)10-9-3/h2H,1H3,(H2,8,11)(H,9,10)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against KDR				Bioorg Med Chem Lett 16: 96-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.042 BindingDB Entry DOI: 10.7270/Q2JH3KRS
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Tie2 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair

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