Compile Data Set for Download or QSAR

Found 1082 hits with Last Name = 'tarantino' and Initial = 'kt'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165186 (US9067917, 3) Show SMILES OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C31H28BrN3O3/c32-22-12-9-20(10-13-22)18-35-29-16-15-24(38-19-23-14-11-21-5-1-4-8-27(21)33-23)17-28(29)34-30(35)25-6-2-3-7-26(25)31(36)37/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,36,37)/t25-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM160551 (US9682971, 3) Show SMILES OC(=O)[C@H]1CCCC[C@@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C31H28BrN3O3/c32-22-12-9-20(10-13-22)18-35-29-16-15-24(38-19-23-14-11-21-5-1-4-8-27(21)33-23)17-28(29)34-30(35)25-6-2-3-7-26(25)31(36)37/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,36,37)/t25-,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164981 (US9067917, 14 | US9682971, 14) Show SMILES CC1(C)[C@H]([C@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1F)C(O)=O |r| Show InChI InChI=1S/C30H25BrFN3O3/c1-30(2)26(27(30)29(36)37)28-34-24-14-21(38-16-20-10-8-17-5-3-4-6-23(17)33-20)11-12-25(24)35(28)15-18-7-9-19(31)13-22(18)32/h3-14,26-27H,15-16H2,1-2H3,(H,36,37)/t26-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164981 (US9067917, 14 | US9682971, 14) Show SMILES CC1(C)[C@H]([C@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1F)C(O)=O |r| Show InChI InChI=1S/C30H25BrFN3O3/c1-30(2)26(27(30)29(36)37)28-34-24-14-21(38-16-20-10-8-17-5-3-4-6-23(17)33-20)11-12-25(24)35(28)15-18-7-9-19(31)13-22(18)32/h3-14,26-27H,15-16H2,1-2H3,(H,36,37)/t26-,27+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164975 (US9067917, 8 | US9682971, 8) Show SMILES CC1(C)CCCC1(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1)C(O)=O Show InChI InChI=1S/C33H32BrN3O3/c1-32(2)16-5-17-33(32,31(38)39)19-30-36-28-18-26(40-21-25-13-10-23-6-3-4-7-27(23)35-25)14-15-29(28)37(30)20-22-8-11-24(34)12-9-22/h3-4,6-15,18H,5,16-17,19-21H2,1-2H3,(H,38,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164975 (US9067917, 8 | US9682971, 8) Show SMILES CC1(C)CCCC1(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1)C(O)=O Show InChI InChI=1S/C33H32BrN3O3/c1-32(2)16-5-17-33(32,31(38)39)19-30-36-28-18-26(40-21-25-13-10-23-6-3-4-7-27(23)35-25)14-15-29(28)37(30)20-22-8-11-24(34)12-9-22/h3-4,6-15,18H,5,16-17,19-21H2,1-2H3,(H,38,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165174 (US9067917, 209 | US9067917, 210 | US9682971, 210) Show SMILES OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3nc4ccccc4s3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C29H26BrN3O3S/c30-19-11-9-18(10-12-19)16-33-25-14-13-20(36-17-27-31-23-7-3-4-8-26(23)37-27)15-24(25)32-28(33)21-5-1-2-6-22(21)29(34)35/h3-4,7-15,21-22H,1-2,5-6,16-17H2,(H,34,35)/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165174 (US9067917, 209 | US9067917, 210 | US9682971, 210) Show SMILES OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3nc4ccccc4s3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C29H26BrN3O3S/c30-19-11-9-18(10-12-19)16-33-25-14-13-20(36-17-27-31-23-7-3-4-8-26(23)37-27)15-24(25)32-28(33)21-5-1-2-6-22(21)29(34)35/h3-4,7-15,21-22H,1-2,5-6,16-17H2,(H,34,35)/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164970 (US9067917, 1 | US9067917, 21 | US9682971, 21) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C31H28BrN3O3/c32-22-12-9-20(10-13-22)18-35-29-16-15-24(38-19-23-14-11-21-5-1-4-8-27(21)33-23)17-28(29)34-30(35)25-6-2-3-7-26(25)31(36)37/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,36,37)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164970 (US9067917, 1 | US9067917, 21 | US9682971, 21) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C31H28BrN3O3/c32-22-12-9-20(10-13-22)18-35-29-16-15-24(38-19-23-14-11-21-5-1-4-8-27(21)33-23)17-28(29)34-30(35)25-6-2-3-7-26(25)31(36)37/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,36,37)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165154 (US9067917, 189 | US9682971, 189) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(c1)-c1ncccn1 |r| Show InChI InChI=1S/C35H31N5O3/c41-35(42)29-11-3-2-10-28(29)34-39-31-20-27(43-22-26-14-13-24-8-1-4-12-30(24)38-26)15-16-32(31)40(34)21-23-7-5-9-25(19-23)33-36-17-6-18-37-33/h1,4-9,12-20,28-29H,2-3,10-11,21-22H2,(H,41,42)/t28?,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165154 (US9067917, 189 | US9682971, 189) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(c1)-c1ncccn1 |r| Show InChI InChI=1S/C35H31N5O3/c41-35(42)29-11-3-2-10-28(29)34-39-31-20-27(43-22-26-14-13-24-8-1-4-12-30(24)38-26)15-16-32(31)40(34)21-23-7-5-9-25(19-23)33-36-17-6-18-37-33/h1,4-9,12-20,28-29H,2-3,10-11,21-22H2,(H,41,42)/t28?,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165188 (US9067917, 42 | US9682971, 42) Show SMILES OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1F |r| Show InChI InChI=1S/C32H27F4N3O4/c33-26-15-23(43-32(34,35)36)12-10-20(26)17-39-29-14-13-22(42-18-21-11-9-19-5-1-4-8-27(19)37-21)16-28(29)38-30(39)24-6-2-3-7-25(24)31(40)41/h1,4-5,8-16,24-25H,2-3,6-7,17-18H2,(H,40,41)/t24-,25+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165008 (US9067917, 41 | US9067917, 43 | US9682971, 42) Show SMILES OC(=O)[C@H]1CCCC[C@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1F |r| Show InChI InChI=1S/C32H27F4N3O4/c33-26-15-23(43-32(34,35)36)12-10-20(26)17-39-29-14-13-22(42-18-21-11-9-19-5-1-4-8-27(19)37-21)16-28(29)38-30(39)24-6-2-3-7-25(24)31(40)41/h1,4-5,8-16,24-25H,2-3,6-7,17-18H2,(H,40,41)/t24-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165103 (US9067917, 138 | US9682971, 138) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@@H]2C(O)=O)c1 |r| Show InChI InChI=1S/C38H36N4O5S/c1-48(45,46)41-29-16-13-26(14-17-29)28-9-6-7-25(21-28)23-42-36-20-19-31(47-24-30-18-15-27-8-2-5-12-34(27)39-30)22-35(36)40-37(42)32-10-3-4-11-33(32)38(43)44/h2,5-9,12-22,32-33,41H,3-4,10-11,23-24H2,1H3,(H,43,44)/t32?,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165103 (US9067917, 138 | US9682971, 138) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@@H]2C(O)=O)c1 |r| Show InChI InChI=1S/C38H36N4O5S/c1-48(45,46)41-29-16-13-26(14-17-29)28-9-6-7-25(21-28)23-42-36-20-19-31(47-24-30-18-15-27-8-2-5-12-34(27)39-30)22-35(36)40-37(42)32-10-3-4-11-33(32)38(43)44/h2,5-9,12-22,32-33,41H,3-4,10-11,23-24H2,1H3,(H,43,44)/t32?,33-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165002 (US9067917, 35 | US9682971, 35) Show SMILES OC(=O)[C@@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(cc1)C#N |r| Show InChI InChI=1S/C32H28N4O3/c33-18-21-9-11-22(12-10-21)19-36-30-16-15-25(39-20-24-14-13-23-5-1-4-8-28(23)34-24)17-29(30)35-31(36)26-6-2-3-7-27(26)32(37)38/h1,4-5,8-17,26-27H,2-3,6-7,19-20H2,(H,37,38)/t26?,27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165002 (US9067917, 35 | US9682971, 35) Show SMILES OC(=O)[C@@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(cc1)C#N |r| Show InChI InChI=1S/C32H28N4O3/c33-18-21-9-11-22(12-10-21)19-36-30-16-15-25(39-20-24-14-13-23-5-1-4-8-28(23)34-24)17-29(30)35-31(36)26-6-2-3-7-27(26)32(37)38/h1,4-5,8-17,26-27H,2-3,6-7,19-20H2,(H,37,38)/t26?,27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165062 (US9067917, 97 | US9682971, 97) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cccc(Cn2c(CC3(CCCC3)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)c1 Show InChI InChI=1S/C38H36N4O5S/c1-48(45,46)41-30-14-11-27(12-15-30)29-9-6-7-26(21-29)24-42-35-18-17-32(47-25-31-16-13-28-8-2-3-10-33(28)39-31)22-34(35)40-36(42)23-38(37(43)44)19-4-5-20-38/h2-3,6-18,21-22,41H,4-5,19-20,23-25H2,1H3,(H,43,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165062 (US9067917, 97 | US9682971, 97) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cccc(Cn2c(CC3(CCCC3)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)c1 Show InChI InChI=1S/C38H36N4O5S/c1-48(45,46)41-30-14-11-27(12-15-30)29-9-6-7-26(21-29)24-42-35-18-17-32(47-25-31-16-13-28-8-2-3-10-33(28)39-31)22-34(35)40-36(42)23-38(37(43)44)19-4-5-20-38/h2-3,6-18,21-22,41H,4-5,19-20,23-25H2,1H3,(H,43,44)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165010 (US9067917, 45 | US9067917, 46 | US9682971, 46) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C32H28F3N3O4/c33-32(34,35)42-23-13-9-20(10-14-23)18-38-29-16-15-24(41-19-22-12-11-21-5-1-4-8-27(21)36-22)17-28(29)37-30(38)25-6-2-3-7-26(25)31(39)40/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,39,40)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165010 (US9067917, 45 | US9067917, 46 | US9682971, 46) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C32H28F3N3O4/c33-32(34,35)42-23-13-9-20(10-14-23)18-38-29-16-15-24(41-19-22-12-11-21-5-1-4-8-27(21)36-22)17-28(29)37-30(38)25-6-2-3-7-26(25)31(39)40/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,39,40)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165133 (US9067917, 168 | US9682971, 168) Show SMILES CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(c1)-c1ccc(NS(C)(=O)=O)cc1)C(O)=O Show InChI InChI=1S/C36H34N4O5S/c1-36(2,35(41)42)21-34-38-32-20-30(45-23-29-16-13-26-8-4-5-10-31(26)37-29)17-18-33(32)40(34)22-24-7-6-9-27(19-24)25-11-14-28(15-12-25)39-46(3,43)44/h4-20,39H,21-23H2,1-3H3,(H,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165133 (US9067917, 168 | US9682971, 168) Show SMILES CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(c1)-c1ccc(NS(C)(=O)=O)cc1)C(O)=O Show InChI InChI=1S/C36H34N4O5S/c1-36(2,35(41)42)21-34-38-32-20-30(45-23-29-16-13-26-8-4-5-10-31(26)37-29)17-18-33(32)40(34)22-24-7-6-9-27(19-24)25-11-14-28(15-12-25)39-46(3,43)44/h4-20,39H,21-23H2,1-3H3,(H,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165017 (US9067917, 52 | US9682971, 52) Show SMILES OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3ccc4cc(F)ccc4n3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C31H27BrFN3O3/c32-21-8-5-19(6-9-21)17-36-29-14-12-24(39-18-23-11-7-20-15-22(33)10-13-27(20)34-23)16-28(29)35-30(36)25-3-1-2-4-26(25)31(37)38/h5-16,25-26H,1-4,17-18H2,(H,37,38)/t25-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165017 (US9067917, 52 | US9682971, 52) Show SMILES OC(=O)[C@@H]1CCCC[C@@H]1c1nc2cc(OCc3ccc4cc(F)ccc4n3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C31H27BrFN3O3/c32-21-8-5-19(6-9-21)17-36-29-14-12-24(39-18-23-11-7-20-15-22(33)10-13-27(20)34-23)16-28(29)35-30(36)25-3-1-2-4-26(25)31(37)38/h5-16,25-26H,1-4,17-18H2,(H,37,38)/t25-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165005 (US9067917, 38 | US9682971, 38) Show SMILES Cc1ccccc1Cn1c(nc2cc(OCc3ccc4ccccc4n3)ccc12)[C@@H]1CCCC[C@@H]1C(O)=O |r| Show InChI InChI=1S/C32H31N3O3/c1-21-8-2-3-10-23(21)19-35-30-17-16-25(38-20-24-15-14-22-9-4-7-13-28(22)33-24)18-29(30)34-31(35)26-11-5-6-12-27(26)32(36)37/h2-4,7-10,13-18,26-27H,5-6,11-12,19-20H2,1H3,(H,36,37)/t26-,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165005 (US9067917, 38 | US9682971, 38) Show SMILES Cc1ccccc1Cn1c(nc2cc(OCc3ccc4ccccc4n3)ccc12)[C@@H]1CCCC[C@@H]1C(O)=O |r| Show InChI InChI=1S/C32H31N3O3/c1-21-8-2-3-10-23(21)19-35-30-17-16-25(38-20-24-15-14-22-9-4-7-13-28(22)33-24)18-29(30)34-31(35)26-11-5-6-12-27(26)32(36)37/h2-4,7-10,13-18,26-27H,5-6,11-12,19-20H2,1H3,(H,36,37)/t26-,27+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165008 (US9067917, 41 | US9067917, 43 | US9682971, 42) Show SMILES OC(=O)[C@H]1CCCC[C@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1F |r| Show InChI InChI=1S/C32H27F4N3O4/c33-26-15-23(43-32(34,35)36)12-10-20(26)17-39-29-14-13-22(42-18-21-11-9-19-5-1-4-8-27(19)37-21)16-28(29)38-30(39)24-6-2-3-7-25(24)31(40)41/h1,4-5,8-16,24-25H,2-3,6-7,17-18H2,(H,40,41)/t24-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM160757 (US9682971, 41) Show SMILES OC(=O)C1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1F Show InChI InChI=1S/C32H27F4N3O4/c33-26-15-23(43-32(34,35)36)12-10-20(26)17-39-29-14-13-22(42-18-21-11-9-19-5-1-4-8-27(19)37-21)16-28(29)38-30(39)24-6-2-3-7-25(24)31(40)41/h1,4-5,8-16,24-25H,2-3,6-7,17-18H2,(H,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164982 (US9067917, 15 | US9682971, 15) Show SMILES OC(=O)[C@H]1CCCC[C@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1F |r| Show InChI InChI=1S/C31H27BrFN3O3/c32-21-11-9-20(26(33)15-21)17-36-29-14-13-23(39-18-22-12-10-19-5-1-4-8-27(19)34-22)16-28(29)35-30(36)24-6-2-3-7-25(24)31(37)38/h1,4-5,8-16,24-25H,2-3,6-7,17-18H2,(H,37,38)/t24-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164982 (US9067917, 15 | US9682971, 15) Show SMILES OC(=O)[C@H]1CCCC[C@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1F |r| Show InChI InChI=1S/C31H27BrFN3O3/c32-21-11-9-20(26(33)15-21)17-36-29-14-13-23(39-18-22-12-10-19-5-1-4-8-27(19)34-22)16-28(29)35-30(36)24-6-2-3-7-25(24)31(37)38/h1,4-5,8-16,24-25H,2-3,6-7,17-18H2,(H,37,38)/t24-,25+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165064 (US9067917, 99 | US9682971, 99) Show SMILES Cn1cc(cn1)-c1cccc(Cn2c(CC3(CCCC3)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)c1 Show InChI InChI=1S/C35H33N5O3/c1-39-22-27(20-36-39)26-9-6-7-24(17-26)21-40-32-14-13-29(43-23-28-12-11-25-8-2-3-10-30(25)37-28)18-31(32)38-33(40)19-35(34(41)42)15-4-5-16-35/h2-3,6-14,17-18,20,22H,4-5,15-16,19,21,23H2,1H3,(H,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165064 (US9067917, 99 | US9682971, 99) Show SMILES Cn1cc(cn1)-c1cccc(Cn2c(CC3(CCCC3)C(O)=O)nc3cc(OCc4ccc5ccccc5n4)ccc23)c1 Show InChI InChI=1S/C35H33N5O3/c1-39-22-27(20-36-39)26-9-6-7-24(17-26)21-40-32-14-13-29(43-23-28-12-11-25-8-2-3-10-30(25)37-28)18-31(32)38-33(40)19-35(34(41)42)15-4-5-16-35/h2-3,6-14,17-18,20,22H,4-5,15-16,19,21,23H2,1H3,(H,41,42)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164970 (US9067917, 1 | US9067917, 21 | US9682971, 21) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C31H28BrN3O3/c32-22-12-9-20(10-13-22)18-35-29-16-15-24(38-19-23-14-11-21-5-1-4-8-27(21)33-23)17-28(29)34-30(35)25-6-2-3-7-26(25)31(36)37/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,36,37)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164970 (US9067917, 1 | US9067917, 21 | US9682971, 21) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1 |r| Show InChI InChI=1S/C31H28BrN3O3/c32-22-12-9-20(10-13-22)18-35-29-16-15-24(38-19-23-14-11-21-5-1-4-8-27(21)33-23)17-28(29)34-30(35)25-6-2-3-7-26(25)31(36)37/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,36,37)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165009 (US9067917, 44 | US9682971, 44) Show SMILES Cc1ccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@H]2C(O)=O)cc1 |r| Show InChI InChI=1S/C32H31N3O3/c1-21-10-12-22(13-11-21)19-35-30-17-16-25(38-20-24-15-14-23-6-2-5-9-28(23)33-24)18-29(30)34-31(35)26-7-3-4-8-27(26)32(36)37/h2,5-6,9-18,26-27H,3-4,7-8,19-20H2,1H3,(H,36,37)/t26?,27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165009 (US9067917, 44 | US9682971, 44) Show SMILES Cc1ccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@H]2C(O)=O)cc1 |r| Show InChI InChI=1S/C32H31N3O3/c1-21-10-12-22(13-11-21)19-35-30-17-16-25(38-20-24-15-14-23-6-2-5-9-28(23)33-24)18-29(30)34-31(35)26-7-3-4-8-27(26)32(36)37/h2,5-6,9-18,26-27H,3-4,7-8,19-20H2,1H3,(H,36,37)/t26?,27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165003 (US9067917, 36 | US9682971, 36) Show SMILES OC(=O)[C@H]1CCCC[C@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccccc1 |r| Show InChI InChI=1S/C31H29N3O3/c35-31(36)26-12-6-5-11-25(26)30-33-28-18-24(16-17-29(28)34(30)19-21-8-2-1-3-9-21)37-20-23-15-14-22-10-4-7-13-27(22)32-23/h1-4,7-10,13-18,25-26H,5-6,11-12,19-20H2,(H,35,36)/t25-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165003 (US9067917, 36 | US9682971, 36) Show SMILES OC(=O)[C@H]1CCCC[C@H]1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccccc1 |r| Show InChI InChI=1S/C31H29N3O3/c35-31(36)26-12-6-5-11-25(26)30-33-28-18-24(16-17-29(28)34(30)19-21-8-2-1-3-9-21)37-20-23-15-14-22-10-4-7-13-27(22)32-23/h1-4,7-10,13-18,25-26H,5-6,11-12,19-20H2,(H,35,36)/t25-,26+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164984 (US9067917, 17 | US9682971, 17) Show SMILES CC1(C)CCC(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2ccc(Br)cc2)(C1)C(O)=O Show InChI InChI=1S/C33H32BrN3O3/c1-32(2)15-16-33(21-32,31(38)39)18-30-36-28-17-26(40-20-25-12-9-23-5-3-4-6-27(23)35-25)13-14-29(28)37(30)19-22-7-10-24(34)11-8-22/h3-14,17H,15-16,18-21H2,1-2H3,(H,38,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164984 (US9067917, 17 | US9682971, 17) Show SMILES CC1(C)CCC(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2ccc(Br)cc2)(C1)C(O)=O Show InChI InChI=1S/C33H32BrN3O3/c1-32(2)15-16-33(21-32,31(38)39)18-30-36-28-17-26(40-20-25-12-9-23-5-3-4-6-27(23)35-25)13-14-29(28)37(30)19-22-7-10-24(34)11-8-22/h3-14,17H,15-16,18-21H2,1-2H3,(H,38,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165023 (US9067917, 58 | US9682971, 58) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2ccc(F)cc2)CCCC1 Show InChI InChI=1S/C31H28FN3O3/c32-23-10-7-21(8-11-23)19-35-28-14-13-25(38-20-24-12-9-22-5-1-2-6-26(22)33-24)17-27(28)34-29(35)18-31(30(36)37)15-3-4-16-31/h1-2,5-14,17H,3-4,15-16,18-20H2,(H,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165028 (US9067917, 63 | US9682971, 63) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2ccc(Cl)cc2)CCCC1 Show InChI InChI=1S/C31H28ClN3O3/c32-23-10-7-21(8-11-23)19-35-28-14-13-25(38-20-24-12-9-22-5-1-2-6-26(22)33-24)17-27(28)34-29(35)18-31(30(36)37)15-3-4-16-31/h1-2,5-14,17H,3-4,15-16,18-20H2,(H,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165023 (US9067917, 58 | US9682971, 58) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2ccc(F)cc2)CCCC1 Show InChI InChI=1S/C31H28FN3O3/c32-23-10-7-21(8-11-23)19-35-28-14-13-25(38-20-24-12-9-22-5-1-2-6-26(22)33-24)17-27(28)34-29(35)18-31(30(36)37)15-3-4-16-31/h1-2,5-14,17H,3-4,15-16,18-20H2,(H,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165028 (US9067917, 63 | US9682971, 63) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2ccc(Cl)cc2)CCCC1 Show InChI InChI=1S/C31H28ClN3O3/c32-23-10-7-21(8-11-23)19-35-28-14-13-25(38-20-24-12-9-22-5-1-2-6-26(22)33-24)17-27(28)34-29(35)18-31(30(36)37)15-3-4-16-31/h1-2,5-14,17H,3-4,15-16,18-20H2,(H,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165014 (US9067917, 49 | US9682971, 49) Show SMILES Cc1cccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@@H]2C(O)=O)c1 |r| Show InChI InChI=1S/C32H31N3O3/c1-21-7-6-8-22(17-21)19-35-30-16-15-25(38-20-24-14-13-23-9-2-5-12-28(23)33-24)18-29(30)34-31(35)26-10-3-4-11-27(26)32(36)37/h2,5-9,12-18,26-27H,3-4,10-11,19-20H2,1H3,(H,36,37)/t26?,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165014 (US9067917, 49 | US9682971, 49) Show SMILES Cc1cccc(Cn2c(nc3cc(OCc4ccc5ccccc5n4)ccc23)C2CCCC[C@@H]2C(O)=O)c1 |r| Show InChI InChI=1S/C32H31N3O3/c1-21-7-6-8-22(17-21)19-35-30-16-15-25(38-20-24-14-13-23-9-2-5-12-28(23)33-24)18-29(30)34-31(35)26-10-3-4-11-27(26)32(36)37/h2,5-9,12-18,26-27H,3-4,10-11,19-20H2,1H3,(H,36,37)/t26?,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM164996 (US9067917, 29 | US9682971, 29) Show SMILES OC(=O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2ccc(Br)cc2)CCCC1 Show InChI InChI=1S/C31H28BrN3O3/c32-23-10-7-21(8-11-23)19-35-28-14-13-25(38-20-24-12-9-22-5-1-2-6-26(22)33-24)17-27(28)34-29(35)18-31(30(36)37)15-3-4-16-31/h1-2,5-14,17H,3-4,15-16,18-20H2,(H,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
JANSSEN PHARMACEUTICA NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9682971 (2017) BindingDB Entry DOI: 10.7270/Q2P26W84
					More data for this Ligand-Target Pair
Arachidonate 5-lipoxygenase-activating protein (Homo sapiens (Human))	BDBM165010 (US9067917, 45 | US9067917, 46 | US9682971, 46) Show SMILES OC(=O)[C@H]1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1 |r| Show InChI InChI=1S/C32H28F3N3O4/c33-32(34,35)42-23-13-9-20(10-14-23)18-38-29-16-15-24(41-19-22-12-11-21-5-1-4-8-27(21)36-22)17-28(29)37-30(38)25-6-2-3-7-26(25)31(39)40/h1,4-5,8-17,25-26H,2-3,6-7,18-19H2,(H,39,40)/t25?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...				US Patent US9067917 (2015) BindingDB Entry DOI: 10.7270/Q24748M5
					More data for this Ligand-Target Pair

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