BindingDB PrimarySearch

Found 15 hits with Last Name = 'crascì' and Initial = 'l'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Collagenase 3 (Homo sapiens (Human))	BDBM24529 ((2Z,5E)-2-(1,2-benzothiazol-3-ylimino)-5-[(4-metho...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM85285 (2-(benzo[d]isothiazol-3-ylimino)-5-benzylidenethia...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM85285 (2-(benzo[d]isothiazol-3-ylimino)-5-benzylidenethia...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM24524 ((2E,5E)-2-(1,3-benzothiazol-2-ylimino)-5-[(4-metho...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.67E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM85282 (2-(benzo[d]-thiazol-2-ylimino)-5-benzylidenethiazo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM85286 (2-(benzo[d]isothiazol-3-ylimino)-5-benzylidenethia...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM85284 (2-(benzo[d]isothiazol-3-ylimino)-5-benzylidenethia...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM85280 (2-(benzo[d]-thiazol-2-ylimino)-thiazolidin-4-one, ...) Show SMILES Oc1csc(Nc2nc3ccccc3s2)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.67E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM85281 (2-(benzo[d]-thiazol-2-ylimino)-5-benzylidenethiazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM85281 (2-(benzo[d]-thiazol-2-ylimino)-5-benzylidenethiazo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM85287 (2-(benzo[d]isothiazol-3-ylimino)-5-benzylidenethia...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.59E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM85283 (2-(benzo[d]-thiazol-2-ylimino)-5-benzylidenethiazo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM85286 (2-(benzo[d]isothiazol-3-ylimino)-5-benzylidenethia...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM85282 (2-(benzo[d]-thiazol-2-ylimino)-5-benzylidenethiazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM24524 ((2E,5E)-2-(1,3-benzothiazol-2-ylimino)-5-[(4-metho...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+4	n/a	n/a	n/a	n/a	7.0	25
University of Catania					Assay Description The MMP assay were performed evaluating the ability of compounds 1a-6a and 1b-6b to prevent the hydrolysis of the fluorescence-quenched peptide subst...				Bioorg Chem 39: 48-52 (2011) Article DOI: 10.1016/j.bioorg.2010.11.002 BindingDB Entry DOI: 10.7270/Q28914DM
University of Catania					More data for this Ligand-Target Pair