Found 19 hits with Last Name = 'goullieux' and Initial = 'l' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50583310
(CHEMBL5082711) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 3.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Nav1.5 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human)) | BDBM50583310
(CHEMBL5082711) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | 8.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Cav1.2 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50583311
(CHEMBL5084930) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.24E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Nav1.5 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human)) | BDBM50583312
(CHEMBL5076143)Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cc(cc1CC)C(=O)NCc1ccccc1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Cav1.2 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50583312
(CHEMBL5076143)Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cc(cc1CC)C(=O)NCc1ccccc1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Nav1.5 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50583314
(CHEMBL5075910)Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cc(cc1CC)S(=O)(=O)NCC | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of hERG expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human)) | BDBM50239382
(Lidamidine)Show InChI InChI=1S/C11H16N4O/c1-7-5-4-6-8(2)9(7)14-11(16)15-10(12)13-3/h4-6H,1-3H3,(H4,12,13,14,15,16) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Cav1.2 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human)) | BDBM50583311
(CHEMBL5084930) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Cav1.2 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human)) | BDBM50583313
(CHEMBL5084225)Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cc(NS(=O)(=O)c2ccccc2)cc1CC | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Cav1.2 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Voltage-dependent L-type calcium channel subunit alpha-1C
(Homo sapiens (Human)) | BDBM50583314
(CHEMBL5075910)Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cc(cc1CC)S(=O)(=O)NCC | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Cav1.2 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50239382
(Lidamidine)Show InChI InChI=1S/C11H16N4O/c1-7-5-4-6-8(2)9(7)14-11(16)15-10(12)13-3/h4-6H,1-3H3,(H4,12,13,14,15,16) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Nav1.5 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50583313
(CHEMBL5084225)Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cc(NS(=O)(=O)c2ccccc2)cc1CC | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Nav1.5 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 5 subunit alpha
(Homo sapiens (Human)) | BDBM50583314
(CHEMBL5075910)Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cc(cc1CC)S(=O)(=O)NCC | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human Nav1.5 expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50583313
(CHEMBL5084225)Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cc(NS(=O)(=O)c2ccccc2)cc1CC | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of hERG expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50583312
(CHEMBL5076143)Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cc(cc1CC)C(=O)NCc1ccccc1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of hERG expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50583311
(CHEMBL5084930) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of hERG expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50583310
(CHEMBL5082711) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of CYP3A4 in human liver microsomes pre-incubated for 30 min in presence of NADPH by LC-LS/MS analysis |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50239382
(Lidamidine)Show InChI InChI=1S/C11H16N4O/c1-7-5-4-6-8(2)9(7)14-11(16)15-10(12)13-3/h4-6H,1-3H3,(H4,12,13,14,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of hERG expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50583310
(CHEMBL5082711) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
PDB
UniChem
| Article
PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of hERG expressed in HEK cells by patch clamp method |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01565
BindingDB Entry DOI: 10.7270/Q2MG7TD0 |
More data for this
Ligand-Target Pair | |
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