Compile Data Set for Download or QSAR

Found 37 hits with Last Name = 'halabelian' and Initial = 'l'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50511923 (CHEMBL4463793) Show SMILES CN(CCN)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H22N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h3-6,9-11,19H,1,7-8,12,18H2,2H3,(H,20,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT6 pre-incubated for 1 to 30 mins using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillati...				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 1 (Homo sapiens)	BDBM178103 (MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...) Show SMILES CC(C)Oc1ccc(cc1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT1 (unknown origin) by scintillation proximity assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM178103 (MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...) Show SMILES CC(C)Oc1ccc(cc1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT3 (unknown origin) by scintillation proximity assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM178103 (MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...) Show SMILES CC(C)Oc1ccc(cc1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT4 (unknown origin) by scintillation proximity assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 8 (Homo sapiens (Human))	BDBM178103 (MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...) Show SMILES CC(C)Oc1ccc(cc1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT8 (unknown origin) by scintillation proximity assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM178103 (MS023 (Compound 3) | N1-((4-(4-isopropoxyphenyl)-1...) Show SMILES CC(C)Oc1ccc(cc1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT6 (unknown origin) by scintillation proximity assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50511923 (CHEMBL4463793) Show SMILES CN(CCN)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H22N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h3-6,9-11,19H,1,7-8,12,18H2,2H3,(H,20,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT6 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50511923 (CHEMBL4463793) Show SMILES CN(CCN)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H22N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h3-6,9-11,19H,1,7-8,12,18H2,2H3,(H,20,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT6 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50511921 (CHEMBL4544587) Show SMILES CCC(=O)Nc1cccc(c1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H24N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h4-6,9-11,19H,3,7-8,12,18H2,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT6 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50511921 (CHEMBL4544587) Show SMILES CCC(=O)Nc1cccc(c1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H24N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h4-6,9-11,19H,3,7-8,12,18H2,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT6 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50194756 (CHEMBL3961701) Show SMILES CNCCN1CCC(CC1)OCc1ccccc1 Show InChI InChI=1S/C15H24N2O/c1-16-9-12-17-10-7-15(8-11-17)18-13-14-5-3-2-4-6-14/h2-6,15-16H,7-13H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT6 (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50194756 (CHEMBL3961701) Show SMILES CNCCN1CCC(CC1)OCc1ccccc1 Show InChI InChI=1S/C15H24N2O/c1-16-9-12-17-10-7-15(8-11-17)18-13-14-5-3-2-4-6-14/h2-6,15-16H,7-13H2,1H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PRMT4 (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50580050 (CHEMBL5075218) Show SMILES Cc1ccc2NC(=O)CN([C@@H](c3cc(C)cc(C)c3)c2c1)C(=O)c1ccc(Br)s1 |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50580051 (CHEMBL5070897) Show SMILES Cc1ccc2NC(=O)CN([C@H](c3cc(C)cc(C)c3)c2c1)C(=O)c1ccc(Br)s1 |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 1 (Homo sapiens)	BDBM50511923 (CHEMBL4463793) Show SMILES CN(CCN)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H22N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h3-6,9-11,19H,1,7-8,12,18H2,2H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT1 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50580053 (CHEMBL5094315) Show SMILES Cc1ccc2NC(=O)CN([C@@H](c3ccc(F)cc3)c2c1)C(=O)c1ccc(Br)o1 |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 8 (Homo sapiens (Human))	BDBM50511923 (CHEMBL4463793) Show SMILES CN(CCN)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H22N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h3-6,9-11,19H,1,7-8,12,18H2,2H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT8 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 8 (Homo sapiens (Human))	BDBM50511921 (CHEMBL4544587) Show SMILES CCC(=O)Nc1cccc(c1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H24N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h4-6,9-11,19H,3,7-8,12,18H2,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT8 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Homo sapiens)	BDBM50511921 (CHEMBL4544587) Show SMILES CCC(=O)Nc1cccc(c1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H24N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h4-6,9-11,19H,3,7-8,12,18H2,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT1 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50580052 (CHEMBL5085334) Show SMILES Cc1ccc2NC(=O)CN(C(c3cc(C)cc(C)c3)c2c1)C(=O)c1ccc(Br)s1 Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50580054 (CHEMBL5084397) Show SMILES Cc1ccc2NC(=O)CN([C@H](c3ccc(F)cc3)c2c1)C(=O)c1ccc(Br)o1 |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	388	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50511923 (CHEMBL4463793) Show SMILES CN(CCN)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H22N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h3-6,9-11,19H,1,7-8,12,18H2,2H3,(H,20,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT4 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50580051 (CHEMBL5070897) Show SMILES Cc1ccc2NC(=O)CN([C@H](c3cc(C)cc(C)c3)c2c1)C(=O)c1ccc(Br)s1 |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLAG-tagged PRMT6 (unknown origin) expressed in HEK293T assessed as reduction in H4R3me2a level measured after 20 hrs by SDS gel electr...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50580055 (CHEMBL5089738) Show SMILES Cc1ccc2NC(=O)CN(C(c3ccc(F)cc3)c2c1)C(=O)c1ccc(Br)o1 Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	755	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of N-terminal hexa-His-tagged/TEV cleavage site fused human full length PRMT6 expressed in baculovirus infected Sf9 insect cells using bio...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50580051 (CHEMBL5070897) Show SMILES Cc1ccc2NC(=O)CN([C@H](c3cc(C)cc(C)c3)c2c1)C(=O)c1ccc(Br)s1 |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of FLAG-tagged PRMT6 (unknown origin) expressed in HEK293T assessed as reduction in H3R2me2a level measured after 20 hrs by SDS gel electr...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02160 BindingDB Entry DOI: 10.7270/Q20V8HN0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50511923 (CHEMBL4463793) Show SMILES CN(CCN)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H22N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h3-6,9-11,19H,1,7-8,12,18H2,2H3,(H,20,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of Flag-tagged PRMT6 (unknown origin) expressed in HEK293 cells incubated for 20 hrs assessed as reduction in H3R2me2a levels				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50511921 (CHEMBL4544587) Show SMILES CCC(=O)Nc1cccc(c1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H24N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h4-6,9-11,19H,3,7-8,12,18H2,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT4 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM50511923 (CHEMBL4463793) Show SMILES CN(CCN)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H22N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h3-6,9-11,19H,1,7-8,12,18H2,2H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT3 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Homo sapiens)	BDBM50511923 (CHEMBL4463793) Show SMILES CN(CCN)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H22N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h3-6,9-11,19H,1,7-8,12,18H2,2H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of PRMT1 in human MCF7 cells assessed as reduction in H4R3me2a levels incubated for 2 days by fluorescence based assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Homo sapiens)	BDBM50511921 (CHEMBL4544587) Show SMILES CCC(=O)Nc1cccc(c1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H24N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h4-6,9-11,19H,3,7-8,12,18H2,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of PRMT1 in human MCF7 cells assessed as reduction in H4R3me2a levels incubated for 2 days by fluorescence based assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT6 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT6 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM50511921 (CHEMBL4544587) Show SMILES CCC(=O)Nc1cccc(c1)-c1c[nH]cc1CN(C)CCN Show InChI InChI=1S/C17H24N4O/c1-3-17(22)20-15-6-4-5-13(9-15)16-11-19-10-14(16)12-21(2)8-7-18/h4-6,9-11,19H,3,7-8,12,18H2,1-2H3,(H,20,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT3 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Homo sapiens)	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT1 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 8 (Homo sapiens (Human))	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT8 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT4 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT3 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair