Found 10 hits with Last Name = 'wessjohann' and Initial = 'l' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cholinesterase
(Equus caballus (Horse)) | BDBM8961
(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)Show InChI InChI=1S/C13H14N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,14,15) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Plant Biochemistry
Curated by ChEMBL
| Assay Description Inhibition of equine serum BChE by Ellman's method |
Bioorg Med Chem 18: 2173-7 (2010)
Article DOI: 10.1016/j.bmc.2010.01.074 BindingDB Entry DOI: 10.7270/Q2R78G5X |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM8961
(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)Show InChI InChI=1S/C13H14N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1,3,5,7H,2,4,6,8H2,(H2,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Plant Biochemistry
Curated by ChEMBL
| Assay Description Inhibition of bovine AChE by Elman's method |
Bioorg Med Chem 18: 2173-7 (2010)
Article DOI: 10.1016/j.bmc.2010.01.074 BindingDB Entry DOI: 10.7270/Q2R78G5X |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Cholinesterase
(Equus caballus (Horse)) | BDBM50004000
((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)Show SMILES CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 |r| Show InChI InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Plant Biochemistry
Curated by ChEMBL
| Assay Description Inhibition of equine serum BChE by Ellman's method |
Bioorg Med Chem 18: 2173-7 (2010)
Article DOI: 10.1016/j.bmc.2010.01.074 BindingDB Entry DOI: 10.7270/Q2R78G5X |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM50004000
((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)Show SMILES CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 |r| Show InChI InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Plant Biochemistry
Curated by ChEMBL
| Assay Description Inhibition of bovine AChE by Elman's method |
Bioorg Med Chem 18: 2173-7 (2010)
Article DOI: 10.1016/j.bmc.2010.01.074 BindingDB Entry DOI: 10.7270/Q2R78G5X |
More data for this Ligand-Target Pair | |
Carboxylic ester hydrolase
(Equus caballus (Horse)) | BDBM50222010
((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)Show SMILES CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 Show InChI InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1 | PDB MMDB
UniProtKB/TrEMBL
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CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Plant Biochemistry
Curated by ChEMBL
| Assay Description Inhibition of equine BChE at 100 uM by Ellman's method |
J Nat Prod 70: 1529-31 (2007)
Article DOI: 10.1021/np070259w BindingDB Entry DOI: 10.7270/Q2GT5P1V |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM10404
((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)Show SMILES COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24 |r,c:12| Show InChI InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Plant Biochemistry
Curated by ChEMBL
| Assay Description Inhibition of bovine AChE by Elman's method |
Bioorg Med Chem 18: 2173-7 (2010)
Article DOI: 10.1016/j.bmc.2010.01.074 BindingDB Entry DOI: 10.7270/Q2R78G5X |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM50308337
(CHEMBL589070 | Infractopicrin)Show InChI InChI=1S/C17H13N2O/c20-15-10-11-4-3-8-18-9-7-13-12-5-1-2-6-14(12)19(15)17(13)16(11)18/h1-2,5-7,9-10H,3-4,8H2/q+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Plant Biochemistry
Curated by ChEMBL
| Assay Description Inhibition of bovine AChE by Elman's method |
Bioorg Med Chem 18: 2173-7 (2010)
Article DOI: 10.1016/j.bmc.2010.01.074 BindingDB Entry DOI: 10.7270/Q2R78G5X |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM50308338
(10-Hydroxy-infractopicrin | CHEMBL589071)Show InChI InChI=1S/C17H12N2O2/c20-11-3-4-14-13(9-11)12-5-7-18-6-1-2-10-8-15(21)19(14)17(12)16(10)18/h3-5,7-9H,1-2,6H2/p+1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.27E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Plant Biochemistry
Curated by ChEMBL
| Assay Description Inhibition of bovine AChE by Elman's method |
Bioorg Med Chem 18: 2173-7 (2010)
Article DOI: 10.1016/j.bmc.2010.01.074 BindingDB Entry DOI: 10.7270/Q2R78G5X |
More data for this Ligand-Target Pair | |
Cholinesterase
(Equus caballus (Horse)) | BDBM10404
((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)Show SMILES COc1ccc2CN(C)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24 |r,c:12| Show InChI InChI=1S/C17H21NO3/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17/h3-6,12,14,19H,7-10H2,1-2H3/t12-,14-,17-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Plant Biochemistry
Curated by ChEMBL
| Assay Description Inhibition of equine serum BChE by Ellman's method |
Bioorg Med Chem 18: 2173-7 (2010)
Article DOI: 10.1016/j.bmc.2010.01.074 BindingDB Entry DOI: 10.7270/Q2R78G5X |
More data for this Ligand-Target Pair | |
Acetylcholinesterase
(Bos taurus (bovine)) | BDBM50222010
((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)Show SMILES CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 Show InChI InChI=1S/C15H21N3O2/c1-15-7-8-17(3)13(15)18(4)12-6-5-10(9-11(12)15)20-14(19)16-2/h5-6,9,13H,7-8H2,1-4H3,(H,16,19)/t13-,15+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Plant Biochemistry
Curated by ChEMBL
| Assay Description Inhibition of bovine AChE at 100 uM by Ellman's method |
J Nat Prod 70: 1529-31 (2007)
Article DOI: 10.1021/np070259w BindingDB Entry DOI: 10.7270/Q2GT5P1V |
More data for this Ligand-Target Pair | |