Compile Data Set for Download or QSAR

Found 159 hits with Last Name = 'pham' and Initial = 'lm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429094 (CHEMBL2335783) Show SMILES Cc1cc(F)ccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-8-11(19)6-7-13(10)21-18(24)15-9-16(23)12-4-3-5-14(17(12)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429098 (CHEMBL2335784) Show SMILES Cc1c(F)cccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-12(19)6-4-7-13(10)21-18(24)15-9-16(23)11-5-3-8-14(17(11)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429070 (CHEMBL2335742) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C17H15N3O4S/c1-25(23,24)20-13-9-5-8-12-15(21)10-14(19-16(12)13)17(22)18-11-6-3-2-4-7-11/h2-10,20H,1H3,(H,18,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429101 (CHEMBL2335780) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C17H13F2N3O4S/c1-27(25,26)22-13-4-2-3-10-15(23)8-14(20-16(10)13)17(24)21-12-6-5-9(18)7-11(12)19/h2-8,22H,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429098 (CHEMBL2335784) Show SMILES Cc1c(F)cccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-12(19)6-4-7-13(10)21-18(24)15-9-16(23)11-5-3-8-14(17(11)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429070 (CHEMBL2335742) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C17H15N3O4S/c1-25(23,24)20-13-9-5-8-12-15(21)10-14(19-16(12)13)17(22)18-11-6-3-2-4-7-11/h2-10,20H,1H3,(H,18,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.90	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr in presence o...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429101 (CHEMBL2335780) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C17H13F2N3O4S/c1-27(25,26)22-13-4-2-3-10-15(23)8-14(20-16(10)13)17(24)21-12-6-5-9(18)7-11(12)19/h2-8,22H,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429094 (CHEMBL2335783) Show SMILES Cc1cc(F)ccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-8-11(19)6-7-13(10)21-18(24)15-9-16(23)12-4-3-5-14(17(12)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429114 (CHEMBL2335769) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1F Show InChI InChI=1S/C17H14FN3O4S/c1-26(24,25)21-13-8-4-5-10-15(22)9-14(19-16(10)13)17(23)20-12-7-3-2-6-11(12)18/h2-9,21H,1H3,(H,19,22)(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429113 (CHEMBL2335770) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1C#N Show InChI InChI=1S/C18H14N4O4S/c1-27(25,26)22-14-8-4-6-12-16(23)9-15(20-17(12)14)18(24)21-13-7-3-2-5-11(13)10-19/h2-9,22H,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363386 (CHEMBL1945889) Show SMILES Cc1ccccc1NC(=O)c1cc(O)c2cccc(O)c2n1 Show InChI InChI=1S/C17H14N2O3/c1-10-5-2-3-7-12(10)19-17(22)13-9-15(21)11-6-4-8-14(20)16(11)18-13/h2-9,20H,1H3,(H,18,21)(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429112 (CHEMBL2335760) Show SMILES Cc1ccccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H17N3O4S/c1-11-6-3-4-8-13(11)20-18(23)15-10-16(22)12-7-5-9-14(17(12)19-15)21-26(2,24)25/h3-10,21H,1-2H3,(H,19,22)(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429070 (CHEMBL2335742) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C17H15N3O4S/c1-25(23,24)20-13-9-5-8-12-15(21)10-14(19-16(12)13)17(22)18-11-6-3-2-4-7-11/h2-10,20H,1H3,(H,18,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363379 (CHEMBL1945882) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C16H12N2O3/c19-13-8-4-7-11-14(20)9-12(18-15(11)13)16(21)17-10-5-2-1-3-6-10/h1-9,19H,(H,17,21)(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429111 (CHEMBL2335786) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)cc1O Show InChI InChI=1S/C17H14FN3O5S/c1-27(25,26)21-12-4-2-3-10-14(22)8-13(19-16(10)12)17(24)20-11-6-5-9(18)7-15(11)23/h2-8,21,23H,1H3,(H,19,22)(H,20,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429110 (CHEMBL2335749) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)NC1CCCCCCCCC1 Show InChI InChI=1S/C21H29N3O4S/c1-29(27,28)24-17-13-9-12-16-19(25)14-18(23-20(16)17)21(26)22-15-10-7-5-3-2-4-6-8-11-15/h9,12-15,24H,2-8,10-11H2,1H3,(H,22,26)(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363389 (CHEMBL1946063) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C16H10F2N2O3/c17-10-5-4-8(6-11(10)18)19-16(23)12-7-14(22)9-2-1-3-13(21)15(9)20-12/h1-7,21H,(H,19,23)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363389 (CHEMBL1946063) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C16H10F2N2O3/c17-10-5-4-8(6-11(10)18)19-16(23)12-7-14(22)9-2-1-3-13(21)15(9)20-12/h1-7,21H,(H,19,23)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429108 (CHEMBL2335779) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1cccc(F)c1F Show InChI InChI=1S/C17H13F2N3O4S/c1-27(25,26)22-12-7-2-4-9-14(23)8-13(20-16(9)12)17(24)21-11-6-3-5-10(18)15(11)19/h2-8,22H,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429109 (CHEMBL2335768) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C17H14FN3O4S/c1-26(24,25)21-13-4-2-3-12-15(22)9-14(20-16(12)13)17(23)19-11-7-5-10(18)6-8-11/h2-9,21H,1H3,(H,19,23)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363379 (CHEMBL1945882) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C16H12N2O3/c19-13-8-4-7-11-14(20)9-12(18-15(11)13)16(21)17-10-5-2-1-3-6-10/h1-9,19H,(H,17,21)(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429070 (CHEMBL2335742) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C17H15N3O4S/c1-25(23,24)20-13-9-5-8-12-15(21)10-14(19-16(12)13)17(22)18-11-6-3-2-4-7-11/h2-10,20H,1H3,(H,18,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429107 (CHEMBL2335782) Show SMILES Cc1ccc(F)cc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-6-7-11(19)8-14(10)21-18(24)15-9-16(23)12-4-3-5-13(17(12)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363387 (CHEMBL1946061) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C16H10F2N2O3/c17-8-4-5-11(10(18)6-8)20-16(23)12-7-14(22)9-2-1-3-13(21)15(9)19-12/h1-7,21H,(H,19,22)(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363383 (CHEMBL1945886) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)cc1 Show InChI InChI=1S/C16H11FN2O3/c17-9-4-6-10(7-5-9)18-16(22)12-8-14(21)11-2-1-3-13(20)15(11)19-12/h1-8,20H,(H,18,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429106 (CHEMBL2335767) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1cccc(F)c1 Show InChI InChI=1S/C17H14FN3O4S/c1-26(24,25)21-13-7-3-6-12-15(22)9-14(20-16(12)13)17(23)19-11-5-2-4-10(18)8-11/h2-9,21H,1H3,(H,19,23)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429078 (CHEMBL2335755) Show SMILES CCCC[C@H](C)NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 |r| Show InChI InChI=1S/C17H23N3O4S/c1-4-5-7-11(2)18-17(22)14-10-15(21)12-8-6-9-13(16(12)19-14)20-25(3,23)24/h6,8-11,20H,4-5,7H2,1-3H3,(H,18,22)(H,19,21)/t11-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli using 2- thio-PAF as substrate incubated for 20...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429105 (CHEMBL2335748) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)NC1CCCCCCCC1 Show InChI InChI=1S/C20H27N3O4S/c1-28(26,27)23-16-12-8-11-15-18(24)13-17(22-19(15)16)20(25)21-14-9-6-4-2-3-5-7-10-14/h8,11-14,23H,2-7,9-10H2,1H3,(H,21,25)(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363386 (CHEMBL1945889) Show SMILES Cc1ccccc1NC(=O)c1cc(O)c2cccc(O)c2n1 Show InChI InChI=1S/C17H14N2O3/c1-10-5-2-3-7-12(10)19-17(22)13-9-15(21)11-6-4-8-14(20)16(11)18-13/h2-9,20H,1H3,(H,18,21)(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363379 (CHEMBL1945882) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C16H12N2O3/c19-13-8-4-7-11-14(20)9-12(18-15(11)13)16(21)17-10-5-2-1-3-6-10/h1-9,19H,(H,17,21)(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminus hexahistidine-tagged human lipoprotein-associated phospholipase A2 expressed in Escherichia coli using 2-thio-PA...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363390 (CHEMBL1946064) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)NC1CCCCC1 Show InChI InChI=1S/C16H18N2O3/c19-13-8-4-7-11-14(20)9-12(18-15(11)13)16(21)17-10-5-2-1-3-6-10/h4,7-10,19H,1-3,5-6H2,(H,17,21)(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429104 (CHEMBL2335747) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)NC1CCCCCCC1 Show InChI InChI=1S/C19H25N3O4S/c1-27(25,26)22-15-11-7-10-14-17(23)12-16(21-18(14)15)19(24)20-13-8-5-3-2-4-6-9-13/h7,10-13,22H,2-6,8-9H2,1H3,(H,20,24)(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429102 (CHEMBL2335778) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1cc(F)ccc1F Show InChI InChI=1S/C17H13F2N3O4S/c1-27(25,26)22-12-4-2-3-10-15(23)8-14(20-16(10)12)17(24)21-13-7-9(18)5-6-11(13)19/h2-8,22H,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429103 (CHEMBL2335771) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1N Show InChI InChI=1S/C17H16N4O4S/c1-26(24,25)21-13-8-4-5-10-15(22)9-14(19-16(10)13)17(23)20-12-7-3-2-6-11(12)18/h2-9,21H,18H2,1H3,(H,19,22)(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429101 (CHEMBL2335780) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)cc1F Show InChI InChI=1S/C17H13F2N3O4S/c1-27(25,26)22-13-4-2-3-10-15(23)8-14(20-16(10)13)17(24)21-12-6-5-9(18)7-11(12)19/h2-8,22H,1H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of TAMRA-tagged AX4870 labeling of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli incubated for 2...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429070 (CHEMBL2335742) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C17H15N3O4S/c1-25(23,24)20-13-9-5-8-12-15(21)10-14(19-16(12)13)17(22)18-11-6-3-2-4-7-11/h2-10,20H,1H3,(H,18,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of TAMRA-tagged AX4870 labeling of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli incubated for 2...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363386 (CHEMBL1945889) Show SMILES Cc1ccccc1NC(=O)c1cc(O)c2cccc(O)c2n1 Show InChI InChI=1S/C17H14N2O3/c1-10-5-2-3-7-12(10)19-17(22)13-9-15(21)11-6-4-8-14(20)16(11)18-13/h2-9,20H,1H3,(H,18,21)(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminus hexahistidine-tagged, TAMRA-tagged human lipoprotein-associated phospholipase A2 expressed in Escherichia coli u...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429100 (CHEMBL2335763) Show SMILES CCc1ccccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C19H19N3O4S/c1-3-12-7-4-5-9-14(12)21-19(24)16-11-17(23)13-8-6-10-15(18(13)20-16)22-27(2,25)26/h4-11,22H,3H2,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429070 (CHEMBL2335742) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1 Show InChI InChI=1S/C17H15N3O4S/c1-25(23,24)20-13-9-5-8-12-15(21)10-14(19-16(12)13)17(22)18-11-6-3-2-4-7-11/h2-10,20H,1H3,(H,18,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr in presence o...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363390 (CHEMBL1946064) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)NC1CCCCC1 Show InChI InChI=1S/C16H18N2O3/c19-13-8-4-7-11-14(20)9-12(18-15(11)13)16(21)17-10-5-2-1-3-6-10/h4,7-10,19H,1-3,5-6H2,(H,17,21)(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminus hexahistidine-tagged, TAMRA-tagged human lipoprotein-associated phospholipase A2 expressed in Escherichia coli u...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363389 (CHEMBL1946063) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)Nc1ccc(F)c(F)c1 Show InChI InChI=1S/C16H10F2N2O3/c17-10-5-4-8(6-11(10)18)19-16(23)12-7-14(22)9-2-1-3-13(21)15(9)20-12/h1-7,21H,(H,19,23)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminus hexahistidine-tagged, TAMRA-tagged human lipoprotein-associated phospholipase A2 expressed in Escherichia coli u...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429098 (CHEMBL2335784) Show SMILES Cc1c(F)cccc1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-12(19)6-4-7-13(10)21-18(24)15-9-16(23)11-5-3-8-14(17(11)20-15)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of TAMRA-tagged AX4870 labeling of human recombinant N-terminal hexahistidine-tagged Lp-PLA2 expressed in Escherichia coli incubated for 2...				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429099 (CHEMBL2335772) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1O Show InChI InChI=1S/C17H15N3O5S/c1-26(24,25)20-12-7-4-5-10-15(22)9-13(18-16(10)12)17(23)19-11-6-2-3-8-14(11)21/h2-9,20-21H,1H3,(H,18,22)(H,19,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Neutral cholesterol ester hydrolase 1 (Homo sapiens (Human))	BDBM50390517 (CHEMBL2071652) Show SMILES CN(C)C(=O)Oc1ccc2cc(Br)ccc2c1Br Show InChI InChI=1S/C13H11Br2NO2/c1-16(2)13(17)18-11-6-3-8-7-9(14)4-5-10(8)12(11)15/h3-7H,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human KIAA1363 expressed in 293T/17 cells using 2-thioacetyl MAGE as substrate preincubated for 20 mins measured after 1 hr				Bioorg Med Chem Lett 22: 5748-51 (2012) Article DOI: 10.1016/j.bmcl.2012.05.102 BindingDB Entry DOI: 10.7270/Q27S7PTD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429097 (CHEMBL2335773) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)Nc1ccccc1Cl Show InChI InChI=1S/C17H14ClN3O4S/c1-26(24,25)21-13-8-4-5-10-15(22)9-14(19-16(10)13)17(23)20-12-7-3-2-6-11(12)18/h2-9,21H,1H3,(H,19,22)(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363385 (CHEMBL1945888) Show SMILES Cc1cccc(NC(=O)c2cc(O)c3cccc(O)c3n2)c1 Show InChI InChI=1S/C17H14N2O3/c1-10-4-2-5-11(8-10)18-17(22)13-9-15(21)12-6-3-7-14(20)16(12)19-13/h2-9,20H,1H3,(H,18,22)(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429096 (CHEMBL2335746) Show SMILES CS(=O)(=O)Nc1cccc2c(O)cc(nc12)C(=O)NC1CCCCCC1 Show InChI InChI=1S/C18H23N3O4S/c1-26(24,25)21-14-10-6-9-13-16(22)11-15(20-17(13)14)18(23)19-12-7-4-2-3-5-8-12/h6,9-12,21H,2-5,7-8H2,1H3,(H,19,23)(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50429095 (CHEMBL2335781) Show SMILES Cc1cccc(F)c1NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 Show InChI InChI=1S/C18H16FN3O4S/c1-10-5-3-7-12(19)16(10)21-18(24)14-9-15(23)11-6-4-8-13(17(11)20-14)22-27(2,25)26/h3-9,22H,1-2H3,(H,20,23)(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma Lp-PLA2 using 2- thio-PAF as substrate incubated for 20 mins prior to substrate addition measured after 1 hr				Bioorg Med Chem Lett 23: 1553-6 (2013) Article DOI: 10.1016/j.bmcl.2012.11.048 BindingDB Entry DOI: 10.7270/Q2571DCV
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363388 (CHEMBL1946062) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)Nc1cccc(F)c1F Show InChI InChI=1S/C16H10F2N2O3/c17-9-4-2-5-10(14(9)18)20-16(23)11-7-13(22)8-3-1-6-12(21)15(8)19-11/h1-7,21H,(H,19,22)(H,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair
Platelet-activating factor acetylhydrolase (Homo sapiens (Human))	BDBM50363393 (CHEMBL1946067) Show SMILES Oc1cccc2c(O)cc(nc12)C(=O)NC12CC3CC(CC(C3)C1)C2 |TLB:18:19:16.17.22:23,THB:18:17:23:24.19.20,20:19:16:22.21.23,20:21:16:24.18.19| Show InChI InChI=1S/C20H22N2O3/c23-16-3-1-2-14-17(24)7-15(21-18(14)16)19(25)22-20-8-11-4-12(9-20)6-13(5-11)10-20/h1-3,7,11-13,23H,4-6,8-10H2,(H,21,24)(H,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
ActivX Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human plasma lipoprotein-associated phospholipase A2 using 2-thio-PAF as substrate preincubated for 20 mins measured 1 hr post substrat...				Bioorg Med Chem Lett 22: 868-71 (2012) Article DOI: 10.1016/j.bmcl.2011.12.045 BindingDB Entry DOI: 10.7270/Q2XG9RMD
					More data for this Ligand-Target Pair

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