Compile Data Set for Download or QSAR

Found 201 hits with Last Name = 'thomas' and Initial = 'lr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520121 (CHEMBL4441671 | US10844044, Example 1) Show SMILES Cc1nc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C25H22Cl2FN5O/c1-15-20(4-6-23(28)31-15)18-9-17(14-33-8-7-32(2)25(33)29)10-19(12-18)24(34)30-13-16-3-5-21(26)22(27)11-16/h3-12,29H,13-14H2,1-2H3,(H,30,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	0.0440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520120 (CHEMBL4476662) Show SMILES Cc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)ccc1Cl Show InChI InChI=1S/C29H28ClFN4O/c1-18-13-22(31)5-6-23(18)25-14-21(17-35-11-10-33(3)29(35)32)15-26-24(25)8-9-34(28(26)36)16-20-4-7-27(30)19(2)12-20/h4-7,10-15,32H,8-9,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0270	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520122 (CHEMBL4528067) Show SMILES Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)NCc1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C27H24F4N4O2/c1-17-10-22(28)6-7-24(17)20-11-19(16-35-9-8-34(2)26(35)32)12-21(14-20)25(36)33-15-18-4-3-5-23(13-18)37-27(29,30)31/h3-14,32H,15-16H2,1-2H3,(H,33,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520123 (CHEMBL4567878) Show SMILES Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C26H25FN4O/c1-18-12-23(27)8-9-24(18)21-13-20(17-31-11-10-30(2)26(31)28)14-22(15-21)25(32)29-16-19-6-4-3-5-7-19/h3-15,28H,16-17H2,1-2H3,(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520124 (CHEMBL4570860) Show SMILES Cc1cccc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)c1 Show InChI InChI=1S/C27H27FN4O/c1-18-5-4-6-20(11-18)16-30-26(33)23-14-21(17-32-10-9-31(3)27(32)29)13-22(15-23)25-8-7-24(28)12-19(25)2/h4-15,29H,16-17H2,1-3H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520125 (CHEMBL4578661) Show SMILES Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C26H24ClFN4O/c1-17-10-23(28)6-7-24(17)20-11-19(16-32-9-8-31(2)26(32)29)12-21(14-20)25(33)30-15-18-4-3-5-22(27)13-18/h3-14,29H,15-16H2,1-2H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520126 (CHEMBL4557848) Show SMILES Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)NCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C26H23Cl2FN4O/c1-16-9-21(29)4-5-22(16)19-10-18(15-33-8-7-32(2)26(33)30)11-20(13-19)25(34)31-14-17-3-6-23(27)24(28)12-17/h3-13,30H,14-15H2,1-2H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520127 (CHEMBL4585441 | US10844044, Example 87) Show SMILES Cc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)ccc1F Show InChI InChI=1S/C27H26F2N4O/c1-17-11-23(28)5-6-24(17)21-12-20(16-33-9-8-32(3)27(33)30)13-22(14-21)26(34)31-15-19-4-7-25(29)18(2)10-19/h4-14,30H,15-16H2,1-3H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0320	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520128 (CHEMBL4555492) Show SMILES Cc1cc(C)cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)c1 Show InChI InChI=1S/C28H29FN4O/c1-18-9-19(2)11-21(10-18)16-31-27(34)24-14-22(17-33-8-7-32(4)28(33)30)13-23(15-24)26-6-5-25(29)12-20(26)3/h5-15,30H,16-17H2,1-4H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0550	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520129 (CHEMBL4593719) Show SMILES Cc1cc(F)ccc1-c1cc(Cn2ccn(C)c2=N)cc(c1)C(=O)NCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C26H23Cl2FN4O/c1-16-7-23(29)3-4-24(16)19-8-18(15-33-6-5-32(2)26(33)30)9-20(12-19)25(34)31-14-17-10-21(27)13-22(28)11-17/h3-13,30H,14-15H2,1-2H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0610	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520130 (CHEMBL4435250) Show SMILES COc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)cc(OC)c1 Show InChI InChI=1S/C28H29FN4O3/c1-18-9-23(29)5-6-26(18)21-10-20(17-33-8-7-32(2)28(33)30)11-22(14-21)27(34)31-16-19-12-24(35-3)15-25(13-19)36-4/h5-15,30H,16-17H2,1-4H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	0.0490	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520131 (CHEMBL4588661) Show SMILES COc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C30H31FN4O3/c1-19-11-22(31)5-6-25(19)27-14-21(18-35-10-9-33(2)30(35)32)15-28-26(27)7-8-34(29(28)36)17-20-12-23(37-3)16-24(13-20)38-4/h5-6,9-16,32H,7-8,17-18H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	<0.0200	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520132 (CHEMBL4453355) Show SMILES COc1cc(CN2CCc3c(cc(Cn4ccn(C5CC5)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C32H33FN4O3/c1-20-12-23(33)4-7-27(20)29-15-22(19-36-10-11-37(32(36)34)24-5-6-24)16-30-28(29)8-9-35(31(30)38)18-21-13-25(39-2)17-26(14-21)40-3/h4,7,10-17,24,34H,5-6,8-9,18-19H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0430	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520133 (CHEMBL4530969) Show SMILES COc1cc(CN2CCc3c(cc(CN4CCSC4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C29H30FN3O3S/c1-18-10-21(30)4-5-24(18)26-13-20(17-33-8-9-37-29(33)31)14-27-25(26)6-7-32(28(27)34)16-19-11-22(35-2)15-23(12-19)36-3/h4-5,10-15,31H,6-9,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0330	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520134 (CHEMBL4556167) Show SMILES COc1cc(CN2CCc3c(cc(CN4CCCC4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C30H32FN3O3/c1-19-11-22(31)6-7-25(19)27-14-21(17-33-9-4-5-29(33)32)15-28-26(27)8-10-34(30(28)35)18-20-12-23(36-2)16-24(13-20)37-3/h6-7,11-16,32H,4-5,8-10,17-18H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0630	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520135 (CHEMBL4463486) Show SMILES COc1cc(CN2CCc3c(cc(Cn4cnn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C29H30FN5O3/c1-18-9-21(30)5-6-24(18)26-12-20(16-35-17-32-33(2)29(35)31)13-27-25(26)7-8-34(28(27)36)15-19-10-22(37-3)14-23(11-19)38-4/h5-6,9-14,17,31H,7-8,15-16H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0230	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520136 (CHEMBL4436638) Show SMILES COc1cccc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)c1 Show InChI InChI=1S/C27H27FN4O2/c1-18-11-23(28)7-8-25(18)21-12-20(17-32-10-9-31(2)27(32)29)13-22(15-21)26(33)30-16-19-5-4-6-24(14-19)34-3/h4-15,29H,16-17H2,1-3H3,(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.160	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520137 (CHEMBL4439051) Show SMILES COc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)ccc1F Show InChI InChI=1S/C27H26F2N4O2/c1-17-10-22(28)5-6-23(17)20-11-19(16-33-9-8-32(2)27(33)30)12-21(14-20)26(34)31-15-18-4-7-24(29)25(13-18)35-3/h4-14,30H,15-16H2,1-3H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0350	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520138 (CHEMBL4463776) Show SMILES Cc1cc(CN2CCc3c(cc(Cn4ccn(C)c4=N)cc3-c3ccc(F)cc3C)C2=O)ccc1F Show InChI InChI=1S/C29H28F2N4O/c1-18-13-22(30)5-6-23(18)25-14-21(17-35-11-10-33(3)29(35)32)15-26-24(25)8-9-34(28(26)36)16-20-4-7-27(31)19(2)12-20/h4-7,10-15,32H,8-9,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	<0.0200	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520139 (CHEMBL4534270) Show SMILES COc1cc(CN2CCc3c(cc(CNC(=N)C4CC4)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C30H32FN3O3/c1-18-10-22(31)6-7-25(18)27-13-19(16-33-29(32)21-4-5-21)14-28-26(27)8-9-34(30(28)35)17-20-11-23(36-2)15-24(12-20)37-3/h6-7,10-15,21H,4-5,8-9,16-17H2,1-3H3,(H2,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520140 (CHEMBL4474045) Show SMILES Cc1cc(CNC(=O)c2cc(Cn3ccn(C)c3=N)cc(c2)-c2ccc(F)cc2C)ccc1Cl Show InChI InChI=1S/C27H26ClFN4O/c1-17-11-23(29)5-6-24(17)21-12-20(16-33-9-8-32(3)27(33)30)13-22(14-21)26(34)31-15-19-4-7-25(28)18(2)10-19/h4-14,30H,15-16H2,1-3H3,(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	0.0900	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50520141 (CHEMBL4462065) Show SMILES COc1cc(CN2CCc3c(cc(Cn4ccoc4=N)cc3-c3ccc(F)cc3C)C2=O)cc(OC)c1 Show InChI InChI=1S/C29H28FN3O4/c1-18-10-21(30)4-5-24(18)26-13-20(17-33-8-9-37-29(33)31)14-27-25(26)6-7-32(28(27)34)16-19-11-22(35-2)15-23(12-19)36-3/h4-5,8-15,31H,6-7,16-17H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	<0.0200	n/a	n/a	n/a	n/a	n/a
Frederick National Laboratory for Cancer Research Curated by ChEMBL					Assay Description Competitive inhibition of human N-terminal His6-SUMO tagged WDR5 (22 to 334 residues) expressed in Escherichia coli BL21-Gold(DE3) cells using 10-mer...				J Med Chem 63: 656-675 (2020) Article DOI: 10.1021/acs.jmedchem.9b01608 BindingDB Entry DOI: 10.7270/Q2HD801W
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531083 (CHEMBL4514537) Show SMILES COc1ccc(Br)cc1S(=O)(=O)Nc1cc(Cl)ccc1O Show InChI InChI=1S/C13H11BrClNO4S/c1-20-12-5-2-8(14)6-13(12)21(18,19)16-10-7-9(15)3-4-11(10)17/h2-7,16-17H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	4.71E+3	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531084 (CHEMBL4459698) Show SMILES Oc1ccc(cc1NS(=O)(=O)c1cc(Br)ccc1O)C1CC1 Show InChI InChI=1S/C15H14BrNO4S/c16-11-4-6-14(19)15(8-11)22(20,21)17-12-7-10(9-1-2-9)3-5-13(12)18/h3-9,17-19H,1-2H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	818	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531083 (CHEMBL4514537) Show SMILES COc1ccc(Br)cc1S(=O)(=O)Nc1cc(Cl)ccc1O Show InChI InChI=1S/C13H11BrClNO4S/c1-20-12-5-2-8(14)6-13(12)21(18,19)16-10-7-9(15)3-4-11(10)17/h2-7,16-17H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	4.71E+3	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531085 (CHEMBL4457898) Show SMILES COc1ccc(Cl)cc1S(=O)(=O)Nc1cc(Cl)ccc1O Show InChI InChI=1S/C13H11Cl2NO4S/c1-20-12-5-3-9(15)7-13(12)21(18,19)16-10-6-8(14)2-4-11(10)17/h2-7,16-17H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.41E+3	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531086 (CHEMBL4445624) Show SMILES COc1ccc(Br)cc1S(=O)(=O)Nc1ccccc1O Show InChI InChI=1S/C13H12BrNO4S/c1-19-12-7-6-9(14)8-13(12)20(17,18)15-10-4-2-3-5-11(10)16/h2-8,15-16H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531087 (CHEMBL4470230) Show SMILES Oc1ccc(Cl)cc1NS(=O)(=O)c1cc(Br)ccc1O Show InChI InChI=1S/C12H9BrClNO4S/c13-7-1-3-11(17)12(5-7)20(18,19)15-9-6-8(14)2-4-10(9)16/h1-6,15-17H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531088 (CHEMBL4462398) Show SMILES Oc1ccc(OC(F)(F)F)cc1NS(=O)(=O)c1cc(Br)ccc1O Show InChI InChI=1S/C13H9BrF3NO5S/c14-7-1-3-11(20)12(5-7)24(21,22)18-9-6-8(2-4-10(9)19)23-13(15,16)17/h1-6,18-20H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	549	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531089 (CHEMBL4569742) Show SMILES Oc1ccc(cc1NS(=O)(=O)c1cc(Br)ccc1O)S(F)(F)(F)(F)F Show InChI InChI=1S/C12H9BrF5NO4S2/c13-7-1-3-11(21)12(5-7)24(22,23)19-9-6-8(2-4-10(9)20)25(14,15,16,17)18/h1-6,19-21H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531090 (CHEMBL4583201) Show SMILES Oc1ccc(cc1NS(=O)(=O)c1cc(Br)ccc1O)C1(CC1)C(F)(F)F Show InChI InChI=1S/C16H13BrF3NO4S/c17-10-2-4-13(23)14(8-10)26(24,25)21-11-7-9(1-3-12(11)22)15(5-6-15)16(18,19)20/h1-4,7-8,21-23H,5-6H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	547	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531091 (CHEMBL4470498) Show SMILES Oc1ccc(cc1NS(=O)(=O)c1cc(Br)ccc1O)C1(CCC1)C#N Show InChI InChI=1S/C17H15BrN2O4S/c18-12-3-5-15(22)16(9-12)25(23,24)20-13-8-11(2-4-14(13)21)17(10-19)6-1-7-17/h2-5,8-9,20-22H,1,6-7H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	289	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair				3D Structure (crystal)
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531092 (CHEMBL4537674) Show SMILES Oc1ccc(cc1NS(=O)(=O)c1cc(Br)ccc1O)C1(CCCCC1)C#N Show InChI InChI=1S/C19H19BrN2O4S/c20-14-5-7-17(24)18(11-14)27(25,26)22-15-10-13(4-6-16(15)23)19(12-21)8-2-1-3-9-19/h4-7,10-11,22-24H,1-3,8-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	229	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531093 (CHEMBL4518711) Show SMILES OC(=O)c1cc(Cl)cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O Show InChI InChI=1S/C13H8BrCl2NO6S/c14-5-1-8(16)12(19)10(2-5)24(22,23)17-9-4-6(15)3-7(11(9)18)13(20)21/h1-4,17-19H,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531094 (CHEMBL4473507) Show SMILES OC(=O)c1cc(cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O)C1CC1 Show InChI InChI=1S/C16H14BrNO6S/c17-10-3-4-13(19)14(7-10)25(23,24)18-12-6-9(8-1-2-8)5-11(15(12)20)16(21)22/h3-8,18-20H,1-2H2,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531095 (CHEMBL4586914) Show SMILES OC(=O)c1cc(cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O)C1CC1 Show InChI InChI=1S/C16H13BrClNO6S/c17-9-5-11(18)15(21)13(6-9)26(24,25)19-12-4-8(7-1-2-7)3-10(14(12)20)16(22)23/h3-7,19-21H,1-2H2,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	207	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531096 (CHEMBL4518895) Show SMILES OC(=O)c1c(O)c(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cc(C2CC2)c1F Show InChI InChI=1S/C16H12BrClFNO6S/c17-7-3-9(18)14(21)11(4-7)27(25,26)20-10-5-8(6-1-2-6)13(19)12(15(10)22)16(23)24/h3-6,20-22H,1-2H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531078 (CHEMBL4575067) Show SMILES OC(=O)c1cc(OC(F)(F)F)cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O Show InChI InChI=1S/C14H9BrF3NO7S/c15-6-1-2-10(20)11(3-6)27(24,25)19-9-5-7(26-14(16,17)18)4-8(12(9)21)13(22)23/h1-5,19-21H,(H,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531097 (CHEMBL4544635) Show SMILES OC(=O)c1cc(cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O)S(F)(F)(F)(F)F Show InChI InChI=1S/C13H9BrF5NO6S2/c14-6-1-2-10(21)11(3-6)27(25,26)20-9-5-7(28(15,16,17,18)19)4-8(12(9)22)13(23)24/h1-5,20-22H,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531098 (CHEMBL4437642) Show SMILES OC(=O)c1cc(cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O)S(F)(F)(F)(F)F Show InChI InChI=1S/C13H8BrClF5NO6S2/c14-5-1-8(15)12(23)10(2-5)28(26,27)21-9-4-6(29(16,17,18,19)20)3-7(11(9)22)13(24)25/h1-4,21-23H,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531099 (CHEMBL4473122) Show SMILES OC(=O)c1cc(NS(=O)(=O)c2cc(Br)ccc2O)cc(c1)C1(CCC1)C#N Show InChI InChI=1S/C18H15BrN2O5S/c19-13-2-3-15(22)16(9-13)27(25,26)21-14-7-11(17(23)24)6-12(8-14)18(10-20)4-1-5-18/h2-3,6-9,21-22H,1,4-5H2,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	229	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531079 (CHEMBL4471282) Show SMILES OC(=O)c1cc(cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O)C1(CCCCC1)C#N Show InChI InChI=1S/C20H19BrN2O6S/c21-13-4-5-16(24)17(10-13)30(28,29)23-15-9-12(8-14(18(15)25)19(26)27)20(11-22)6-2-1-3-7-20/h4-5,8-10,23-25H,1-3,6-7H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531100 (CHEMBL4483349) Show SMILES OC(=O)c1cc(cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O)C1(CCCCC1)C#N Show InChI InChI=1S/C20H18BrClN2O6S/c21-12-8-14(22)18(26)16(9-12)31(29,30)24-15-7-11(6-13(17(15)25)19(27)28)20(10-23)4-2-1-3-5-20/h6-9,24-26H,1-5H2,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531101 (CHEMBL4465545) Show SMILES CNC(=O)c1c(O)c(NS(=O)(=O)c2cc(Br)ccc2O)cc(C2CC2)c1F Show InChI InChI=1S/C17H16BrFN2O5S/c1-20-17(24)14-15(19)10(8-2-3-8)7-11(16(14)23)21-27(25,26)13-6-9(18)4-5-12(13)22/h4-8,21-23H,2-3H2,1H3,(H,20,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531102 (CHEMBL4594023) Show SMILES CNC(=O)c1c(O)c(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cc(C2CC2)c1F Show InChI InChI=1S/C17H15BrClFN2O5S/c1-21-17(25)13-14(20)9(7-2-3-7)6-11(16(13)24)22-28(26,27)12-5-8(18)4-10(19)15(12)23/h4-7,22-24H,2-3H2,1H3,(H,21,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	238	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531103 (CHEMBL4455721) Show SMILES CNC(=O)c1cc(cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O)S(F)(F)(F)(F)F Show InChI InChI=1S/C14H11BrClF5N2O5S2/c1-22-14(26)8-4-7(30(17,18,19,20)21)5-10(12(8)24)23-29(27,28)11-3-6(15)2-9(16)13(11)25/h2-5,23-25H,1H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531104 (CHEMBL4549544) Show SMILES CNC(=O)c1cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)cc(c1)C1(CCC1)C#N Show InChI InChI=1S/C19H17BrClN3O4S/c1-23-18(26)11-5-12(19(10-22)3-2-4-19)7-14(6-11)24-29(27,28)16-9-13(20)8-15(21)17(16)25/h5-9,24-25H,2-4H2,1H3,(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531105 (CHEMBL4543629) Show SMILES CNC(=O)c1cc(cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O)C1(CCC1)C#N Show InChI InChI=1S/C19H18BrN3O5S/c1-22-18(26)13-7-11(19(10-21)5-2-6-19)8-14(17(13)25)23-29(27,28)16-9-12(20)3-4-15(16)24/h3-4,7-9,23-25H,2,5-6H2,1H3,(H,22,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	566	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531106 (CHEMBL4441794) Show SMILES CNC(=O)c1cc(cc(NS(=O)(=O)c2cc(Br)cc(Cl)c2O)c1O)C1(CCCCC1)C#N Show InChI InChI=1S/C21H21BrClN3O5S/c1-25-20(29)14-7-12(21(11-24)5-3-2-4-6-21)8-16(18(14)27)26-32(30,31)17-10-13(22)9-15(23)19(17)28/h7-10,26-28H,2-6H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	362	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair
WD repeat-containing protein 5 (Homo sapiens (Human))	BDBM50531107 (CHEMBL4551051) Show SMILES COCCNc1cc(cc(NS(=O)(=O)c2cc(Br)ccc2O)c1O)C1(CCC1)C#N Show InChI InChI=1S/C20H22BrN3O5S/c1-29-8-7-23-15-9-13(20(12-22)5-2-6-20)10-16(19(15)26)24-30(27,28)18-11-14(21)3-4-17(18)25/h3-4,9-11,23-26H,2,5-8H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	757	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Displacement of FITC-labelled DEEEIDVVSVE from N-terminal SUMO-fused 6His-tagged WDR5 (unknown origin) (22 to 334 residues) expressed in Escherichia ...				J Med Chem 62: 11232-11259 (2019) Article DOI: 10.1021/acs.jmedchem.9b01411 BindingDB Entry DOI: 10.7270/Q2B85CM0
					More data for this Ligand-Target Pair

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