Compile Data Set for Download or QSAR

Found 10 hits with Last Name = 'cormier' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029225 ((E)-3-(2,5-Dihydroxy-phenyl)-acrylic acid phenethy...) Show SMILES Oc1ccc(O)c(\C=C\C(=O)OCCc2ccccc2)c1 Show InChI InChI=1S/C17H16O4/c18-15-7-8-16(19)14(12-15)6-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Moncton Curated by ChEMBL					Assay Description Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...				Eur J Med Chem 179: 347-357 (2019) Article DOI: 10.1016/j.ejmech.2019.06.060 BindingDB Entry DOI: 10.7270/Q2125X31
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029225 ((E)-3-(2,5-Dihydroxy-phenyl)-acrylic acid phenethy...) Show SMILES Oc1ccc(O)c(\C=C\C(=O)OCCc2ccccc2)c1 Show InChI InChI=1S/C17H16O4/c18-15-7-8-16(19)14(12-15)6-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-6+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Moncton Curated by ChEMBL					Assay Description Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...				Eur J Med Chem 179: 347-357 (2019) Article DOI: 10.1016/j.ejmech.2019.06.060 BindingDB Entry DOI: 10.7270/Q2125X31
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50530377 (CHEMBL4579523) Show SMILES Oc1ccc(O)c(\C=C\C(=O)CCc2ccccc2)c1 Show InChI InChI=1S/C17H16O3/c18-15(8-6-13-4-2-1-3-5-13)9-7-14-12-16(19)10-11-17(14)20/h1-5,7,9-12,19-20H,6,8H2/b9-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Moncton Curated by ChEMBL					Assay Description Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...				Eur J Med Chem 179: 347-357 (2019) Article DOI: 10.1016/j.ejmech.2019.06.060 BindingDB Entry DOI: 10.7270/Q2125X31
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50530377 (CHEMBL4579523) Show SMILES Oc1ccc(O)c(\C=C\C(=O)CCc2ccccc2)c1 Show InChI InChI=1S/C17H16O3/c18-15(8-6-13-4-2-1-3-5-13)9-7-14-12-16(19)10-11-17(14)20/h1-5,7,9-12,19-20H,6,8H2/b9-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Moncton Curated by ChEMBL					Assay Description Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...				Eur J Med Chem 179: 347-357 (2019) Article DOI: 10.1016/j.ejmech.2019.06.060 BindingDB Entry DOI: 10.7270/Q2125X31
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50530376 (CHEMBL4582170) Show SMILES Oc1cccc(\C=C\C(=O)OCCc2ccccc2)c1O Show InChI InChI=1S/C17H16O4/c18-15-8-4-7-14(17(15)20)9-10-16(19)21-12-11-13-5-2-1-3-6-13/h1-10,18,20H,11-12H2/b10-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Moncton Curated by ChEMBL					Assay Description Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...				Eur J Med Chem 179: 347-357 (2019) Article DOI: 10.1016/j.ejmech.2019.06.060 BindingDB Entry DOI: 10.7270/Q2125X31
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50530376 (CHEMBL4582170) Show SMILES Oc1cccc(\C=C\C(=O)OCCc2ccccc2)c1O Show InChI InChI=1S/C17H16O4/c18-15-8-4-7-14(17(15)20)9-10-16(19)21-12-11-13-5-2-1-3-6-13/h1-10,18,20H,11-12H2/b10-9+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Moncton Curated by ChEMBL					Assay Description Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...				Eur J Med Chem 179: 347-357 (2019) Article DOI: 10.1016/j.ejmech.2019.06.060 BindingDB Entry DOI: 10.7270/Q2125X31
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029207 ((E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid phenethy...) Show SMILES Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O Show InChI InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Moncton Curated by ChEMBL					Assay Description Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...				Eur J Med Chem 179: 347-357 (2019) Article DOI: 10.1016/j.ejmech.2019.06.060 BindingDB Entry DOI: 10.7270/Q2125X31
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50029207 ((E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid phenethy...) Show SMILES Oc1ccc(\C=C\C(=O)OCCc2ccccc2)cc1O Show InChI InChI=1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Moncton Curated by ChEMBL					Assay Description Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...				Eur J Med Chem 179: 347-357 (2019) Article DOI: 10.1016/j.ejmech.2019.06.060 BindingDB Entry DOI: 10.7270/Q2125X31
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Moncton Curated by ChEMBL					Assay Description Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...				Eur J Med Chem 179: 347-357 (2019) Article DOI: 10.1016/j.ejmech.2019.06.060 BindingDB Entry DOI: 10.7270/Q2125X31
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Homo sapiens (Human))	BDBM50000541 ((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...) Show SMILES CC(N(O)C(N)=O)c1cc2ccccc2s1 Show InChI InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	2.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Moncton Curated by ChEMBL					Assay Description Inhibition of 5-LO in human PMNL cells assessed as reduction in leukotriene formation preincubated for 5 mins followed by thapsigargin stimulation me...				Eur J Med Chem 179: 347-357 (2019) Article DOI: 10.1016/j.ejmech.2019.06.060 BindingDB Entry DOI: 10.7270/Q2125X31
					More data for this Ligand-Target Pair