Compile Data Set for Download or QSAR

Found 1188 hits with Last Name = 'helm' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564911 (CHEMBL4786755) Show SMILES CC(=O)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564897 (CHEMBL4780406) Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564897 (CHEMBL4780406) Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564917 (CHEMBL4791577) Show SMILES C\C(=N/NC(N)=S)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564913 (CHEMBL4795119) Show SMILES C\C(=N/NC(N)=O)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564913 (CHEMBL4795119) Show SMILES C\C(=N/NC(N)=O)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA9 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564917 (CHEMBL4791577) Show SMILES C\C(=N/NC(N)=S)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564911 (CHEMBL4786755) Show SMILES CC(=O)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564911 (CHEMBL4786755) Show SMILES CC(=O)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564917 (CHEMBL4791577) Show SMILES C\C(=N/NC(N)=S)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564901 (CHEMBL4781301) Show SMILES Cc1c(nnn1-c1ccc(cc1)C(O)=O)-c1nn(cc1\C=N\O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	154	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564913 (CHEMBL4795119) Show SMILES C\C(=N/NC(N)=O)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	213	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564901 (CHEMBL4781301) Show SMILES Cc1c(nnn1-c1ccc(cc1)C(O)=O)-c1nn(cc1\C=N\O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	239	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564897 (CHEMBL4780406) Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	252	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564916 (CHEMBL4792785) Show SMILES C\C(=N/NC(N)=S)c1nnn(c1C)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	416	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564896 (CHEMBL4797489) Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1nnn(c1C)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	551	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564896 (CHEMBL4797489) Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1nnn(c1C)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	566	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50009568 ((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...) Show SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(SC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C22H25NO5S/c1-12(24)23-16-8-6-13-10-18(26-2)21(27-3)22(28-4)20(13)14-7-9-19(29-5)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50280009 (CHEMBL88059 | N-((S)-1,2,3-Trimethoxy-10-methylami...) Show SMILES CNc1ccc2-c3c(CC[C@H](NC(C)=O)c2cc1=O)cc(OC)c(OC)c3OC Show InChI InChI=1S/C22H26N2O5/c1-12(25)24-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-17(23-2)18(26)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,26)(H,24,25)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50564901 (CHEMBL4781301) Show SMILES Cc1c(nnn1-c1ccc(cc1)C(O)=O)-c1nn(cc1\C=N\O)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	2.25E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA9 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50280008 (2-Methylamino-5-(2,3,4-trimethoxy-phenyl)-cyclohep...) Show SMILES CNc1ccc(ccc1=O)-c1ccc(OC)c(OC)c1OC Show InChI InChI=1S/C17H19NO4/c1-18-13-8-5-11(6-9-14(13)19)12-7-10-15(20-2)17(22-4)16(12)21-3/h5-10H,1-4H3,(H,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) Show SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50564913 (CHEMBL4795119) Show SMILES C\C(=N/NC(N)=O)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA9 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564901 (CHEMBL4781301) Show SMILES Cc1c(nnn1-c1ccc(cc1)C(O)=O)-c1nn(cc1\C=N\O)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	4.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564912 (CHEMBL4786875) Show SMILES CC(=O)c1nnn(c1C)-c1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564914 (CHEMBL4792442) Show SMILES C\C(=N/NC(N)=O)c1nnn(c1C)-c1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.86E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50564917 (CHEMBL4791577) Show SMILES C\C(=N/NC(N)=S)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA9 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564902 (CHEMBL4788698) Show SMILES Cc1c(nnn1-c1ccc(cc1)S(N)(=O)=O)-c1nn(cc1\C=N\O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	7.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50564897 (CHEMBL4780406) Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA9 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50564911 (CHEMBL4786755) Show SMILES CC(=O)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA9 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50279934 (2-Methoxy-5-(2,3,4-trimethoxy-phenyl)-cyclohepta-2...) Show SMILES COc1ccc(c(OC)c1OC)-c1ccc(OC)c(=O)cc1 Show InChI InChI=1S/C17H18O5/c1-19-14-9-6-11(5-8-13(14)18)12-7-10-15(20-2)17(22-4)16(12)21-3/h5-10H,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem	PDB Article	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564902 (CHEMBL4788698) Show SMILES Cc1c(nnn1-c1ccc(cc1)S(N)(=O)=O)-c1nn(cc1\C=N\O)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Tubulin alpha-1A chain (Sus scrofa (Pig))	BDBM50280007 (2-Methylsulfanyl-5-(2,3,4-trimethoxy-phenyl)-cyclo...) Show SMILES COc1ccc(c(OC)c1OC)-c1ccc(SC)c(=O)cc1 Show InChI InChI=1S/C17H18O4S/c1-19-14-9-7-12(16(20-2)17(14)21-3)11-5-8-13(18)15(22-4)10-6-11/h5-10H,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay				Bioorg Med Chem Lett 1: 471-476 (1991) Article DOI: 10.1016/S0960-894X(01)81108-2 BindingDB Entry DOI: 10.7270/Q2Z89C92
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564914 (CHEMBL4792442) Show SMILES C\C(=N/NC(N)=O)c1nnn(c1C)-c1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.63E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564912 (CHEMBL4786875) Show SMILES CC(=O)c1nnn(c1C)-c1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50564918 (CHEMBL4779437) Show SMILES C\C(=N/NC(N)=S)c1nnn(c1C)-c1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.25E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA2 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564918 (CHEMBL4779437) Show SMILES C\C(=N/NC(N)=S)c1nnn(c1C)-c1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564919 (CHEMBL4788147) Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1nnn(c1C)-c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564896 (CHEMBL4797489) Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1nnn(c1C)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564898 (CHEMBL4794089) Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1)c1nnn(c1C)-c1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564899 (CHEMBL4786489) Show SMILES Cc1c(nnn1-c1ccc(Cl)cc1)-c1nn(cc1\C=N\O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564900 (CHEMBL4798519) Show SMILES Cc1c(nnn1-c1ccc(F)cc1)-c1nn(cc1\C=N\O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50564902 (CHEMBL4788698) Show SMILES Cc1c(nnn1-c1ccc(cc1)S(N)(=O)=O)-c1nn(cc1\C=N\O)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA12 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564915 (CHEMBL4790291) Show SMILES C\C(=N/NC(N)=S)c1nnn(c1C)-c1ccc(F)cc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564916 (CHEMBL4792785) Show SMILES C\C(=N/NC(N)=S)c1nnn(c1C)-c1ccc(cc1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50564918 (CHEMBL4779437) Show SMILES C\C(=N/NC(N)=S)c1nnn(c1C)-c1ccc(cc1)S(=O)(=O)Nc1nccs1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human CA1 by stopped-flow carbon dioxide hydration assay				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112439 BindingDB Entry DOI: 10.7270/Q2057KNJ
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 1188 total )  |  Next  |  Last  >>

Jump to: