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SMILES: CNc1ccc(ccc1=O)-c1ccc(OC)c(OC)c1OC

InChI Key: InChIKey=QFGFYLMUCXJTQE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280008   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin alpha-1A chain


(Sus scrofa (Pig))		BDBM50280008
PNG
(2-Methylamino-5-(2,3,4-trimethoxy-phenyl)-cyclohep...)
Show SMILES CNc1ccc(ccc1=O)-c1ccc(OC)c(OC)c1OC
Show InChI InChI=1S/C17H19NO4/c1-18-13-8-5-11(6-9-14(13)19)12-7-10-15(20-2)17(22-4)16(12)21-3/h5-10H,1-4H3,(H,18,19)
PDB
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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
 2.50E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assay

Bioorg Med Chem Lett 1: 471-476 (1991)


Article DOI: 10.1016/S0960-894X(01)81108-2
BindingDB Entry DOI: 10.7270/Q2Z89C92
More data for this
Ligand-Target Pair