Compile Data Set for Download or QSAR

Found 141 hits with Last Name = 'makowska-grzyska' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432765 (CHEMBL2348794) Show SMILES C[C@H](Nc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H16Cl2N4O2/c1-12(25-16-4-2-3-15(22)19(16)23)20(28)26-14-5-6-18-17(11-14)27-21(29-18)13-7-9-24-10-8-13/h2-12,25H,1H3,(H,26,28)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432774 (CHEMBL2348627) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2nc(oc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H15Cl2N3O3/c1-12(28-17-4-2-3-15(22)19(17)23)20(27)25-14-5-6-16-18(11-14)29-21(26-16)13-7-9-24-10-8-13/h2-12H,1H3,(H,25,27)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432765 (CHEMBL2348794) Show SMILES C[C@H](Nc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H16Cl2N4O2/c1-12(25-16-4-2-3-15(22)19(16)23)20(28)26-14-5-6-18-17(11-14)27-21(29-18)13-7-9-24-10-8-13/h2-12,25H,1H3,(H,26,28)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432790 (CHEMBL2348796) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H15Cl2N3O3/c1-12(28-18-4-2-3-15(22)19(18)23)20(27)25-14-5-6-17-16(11-14)26-21(29-17)13-7-9-24-10-8-13/h2-12H,1H3,(H,25,27)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432783 (CHEMBL2348803) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1cncs1 |r| Show InChI InChI=1S/C19H13Cl2N3O3S/c1-10(26-15-4-2-3-12(20)17(15)21)18(25)23-11-5-6-14-13(7-11)24-19(27-14)16-8-22-9-28-16/h2-10H,1H3,(H,23,25)/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432765 (CHEMBL2348794) Show SMILES C[C@H](Nc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H16Cl2N4O2/c1-12(25-16-4-2-3-15(22)19(16)23)20(28)26-14-5-6-18-17(11-14)27-21(29-18)13-7-9-24-10-8-13/h2-12,25H,1H3,(H,26,28)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432765 (CHEMBL2348794) Show SMILES C[C@H](Nc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H16Cl2N4O2/c1-12(25-16-4-2-3-15(22)19(16)23)20(28)26-14-5-6-18-17(11-14)27-21(29-18)13-7-9-24-10-8-13/h2-12,25H,1H3,(H,26,28)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432788 (CHEMBL2348798) Show SMILES C[C@H](Oc1cccc(c1Cl)[N+]([O-])=O)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H15ClN4O5/c1-12(30-18-4-2-3-16(19(18)22)26(28)29)20(27)24-14-5-6-17-15(11-14)25-21(31-17)13-7-9-23-10-8-13/h2-12H,1H3,(H,24,27)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432783 (CHEMBL2348803) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1cncs1 |r| Show InChI InChI=1S/C19H13Cl2N3O3S/c1-10(26-15-4-2-3-12(20)17(15)21)18(25)23-11-5-6-14-13(7-11)24-19(27-14)16-8-22-9-28-16/h2-10H,1H3,(H,23,25)/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432782 (CHEMBL2348804) Show SMILES C[C@H](Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1cncs1 |r| Show InChI InChI=1S/C23H17N3O3S/c1-14(28-19-8-4-6-15-5-2-3-7-17(15)19)22(27)25-16-9-10-20-18(11-16)26-23(29-20)21-12-24-13-30-21/h2-14H,1H3,(H,25,27)/t14-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432790 (CHEMBL2348796) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H15Cl2N3O3/c1-12(28-18-4-2-3-15(22)19(18)23)20(27)25-14-5-6-17-16(11-14)26-21(29-17)13-7-9-24-10-8-13/h2-12H,1H3,(H,25,27)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432790 (CHEMBL2348796) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H15Cl2N3O3/c1-12(28-18-4-2-3-15(22)19(18)23)20(27)25-14-5-6-17-16(11-14)26-21(29-17)13-7-9-24-10-8-13/h2-12H,1H3,(H,25,27)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432774 (CHEMBL2348627) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2nc(oc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H15Cl2N3O3/c1-12(28-17-4-2-3-15(22)19(17)23)20(27)25-14-5-6-16-18(11-14)29-21(26-16)13-7-9-24-10-8-13/h2-12H,1H3,(H,25,27)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432782 (CHEMBL2348804) Show SMILES C[C@H](Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1cncs1 |r| Show InChI InChI=1S/C23H17N3O3S/c1-14(28-19-8-4-6-15-5-2-3-7-17(15)19)22(27)25-16-9-10-20-18(11-16)26-23(29-20)21-12-24-13-30-21/h2-14H,1H3,(H,25,27)/t14-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432788 (CHEMBL2348798) Show SMILES C[C@H](Oc1cccc(c1Cl)[N+]([O-])=O)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H15ClN4O5/c1-12(30-18-4-2-3-16(19(18)22)26(28)29)20(27)24-14-5-6-17-15(11-14)25-21(31-17)13-7-9-23-10-8-13/h2-12H,1H3,(H,24,27)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432791 (CHEMBL2348823) Show SMILES C[C@H](Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C25H19N3O3/c1-16(30-22-8-4-6-17-5-2-3-7-20(17)22)24(29)27-19-9-10-23-21(15-19)28-25(31-23)18-11-13-26-14-12-18/h2-16H,1H3,(H,27,29)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432773 (CHEMBL2348628) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2nc(oc2c1)-c1cncs1 |r| Show InChI InChI=1S/C19H13Cl2N3O3S/c1-10(26-14-4-2-3-12(20)17(14)21)18(25)23-11-5-6-13-15(7-11)27-19(24-13)16-8-22-9-28-16/h2-10H,1H3,(H,23,25)/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432791 (CHEMBL2348823) Show SMILES C[C@H](Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C25H19N3O3/c1-16(30-22-8-4-6-17-5-2-3-7-20(17)22)24(29)27-19-9-10-23-21(15-19)28-25(31-23)18-11-13-26-14-12-18/h2-16H,1H3,(H,27,29)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432791 (CHEMBL2348823) Show SMILES C[C@H](Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C25H19N3O3/c1-16(30-22-8-4-6-17-5-2-3-7-20(17)22)24(29)27-19-9-10-23-21(15-19)28-25(31-23)18-11-13-26-14-12-18/h2-16H,1H3,(H,27,29)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432789 (CHEMBL2348797) Show SMILES C[C@H](Oc1cccc(c1Cl)C(F)(F)F)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C22H15ClF3N3O3/c1-12(31-18-4-2-3-15(19(18)23)22(24,25)26)20(30)28-14-5-6-17-16(11-14)29-21(32-17)13-7-9-27-10-8-13/h2-12H,1H3,(H,28,30)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432790 (CHEMBL2348796) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C21H15Cl2N3O3/c1-12(28-18-4-2-3-15(22)19(18)23)20(27)25-14-5-6-17-16(11-14)26-21(29-17)13-7-9-24-10-8-13/h2-12H,1H3,(H,25,27)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432764 (CHEMBL2348795) Show SMILES C[C@H](Nc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C25H20N4O2/c1-16(27-21-8-4-6-17-5-2-3-7-20(17)21)24(30)28-19-9-10-23-22(15-19)29-25(31-23)18-11-13-26-14-12-18/h2-16,27H,1H3,(H,28,30)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432791 (CHEMBL2348823) Show SMILES C[C@H](Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C25H19N3O3/c1-16(30-22-8-4-6-17-5-2-3-7-20(17)22)24(29)27-19-9-10-23-21(15-19)28-25(31-23)18-11-13-26-14-12-18/h2-16H,1H3,(H,27,29)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432764 (CHEMBL2348795) Show SMILES C[C@H](Nc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C25H20N4O2/c1-16(27-21-8-4-6-17-5-2-3-7-20(17)21)24(30)28-19-9-10-23-22(15-19)29-25(31-23)18-11-13-26-14-12-18/h2-16,27H,1H3,(H,28,30)/t16-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432780 (CHEMBL2348806) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1nccs1 |r| Show InChI InChI=1S/C19H13Cl2N3O3S/c1-10(26-15-4-2-3-12(20)16(15)21)17(25)23-11-5-6-14-13(9-11)24-18(27-14)19-22-7-8-28-19/h2-10H,1H3,(H,23,25)/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432801 (CHEMBL2348811) Show SMILES CC(Oc1ccccc1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C21H16ClN3O3/c1-13(27-18-5-3-2-4-16(18)22)20(26)24-15-6-7-19-17(12-15)25-21(28-19)14-8-10-23-11-9-14/h2-13H,1H3,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432797 (CHEMBL2348815) Show SMILES CC(Oc1cccc(Cl)c1)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C21H16ClN3O3/c1-13(27-17-4-2-3-15(22)11-17)20(26)24-16-5-6-19-18(12-16)25-21(28-19)14-7-9-23-10-8-14/h2-13H,1H3,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50040476 (CHEMBL3360632) Show SMILES COc1cc(NC(=O)Cn2ncc3c2c2ccccc2oc3=O)ccc1Cl Show InChI InChI=1S/C19H14ClN3O4/c1-26-16-8-11(6-7-14(16)20)22-17(24)10-23-18-12-4-2-3-5-15(12)27-19(25)13(18)9-21-23/h2-9H,10H2,1H3,(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of Houston Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum IMPDH assessed as reduction in NADH production				J Med Chem 57: 10544-50 (2014) Article DOI: 10.1021/jm501527z BindingDB Entry DOI: 10.7270/Q2XS5X1F
					More data for this Ligand-Target Pair				3D Structure (crystal)
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432767 (CHEMBL2348635) Show SMILES C[C@@H](C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1)c1ccccc1 |r| Show InChI InChI=1S/C21H17N3O2/c1-14(15-5-3-2-4-6-15)20(25)23-17-7-8-19-18(13-17)24-21(26-19)16-9-11-22-12-10-16/h2-14H,1H3,(H,23,25)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432793 (CHEMBL2348821) Show SMILES CC(C)C(Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C27H23N3O3/c1-17(2)25(32-23-9-5-7-18-6-3-4-8-21(18)23)26(31)29-20-10-11-24-22(16-20)30-27(33-24)19-12-14-28-15-13-19/h3-17,25H,1-2H3,(H,29,31)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432779 (CHEMBL2348807) Show SMILES C[C@H](Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccc[nH]1 |r| Show InChI InChI=1S/C24H19N3O3/c1-15(29-21-10-4-7-16-6-2-3-8-18(16)21)23(28)26-17-11-12-22-20(14-17)27-24(30-22)19-9-5-13-25-19/h2-15,25H,1H3,(H,26,28)/t15-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432795 (CHEMBL2348819) Show SMILES CC(Oc1ccc(Cl)c2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C25H18ClN3O3/c1-15(31-22-9-7-20(26)18-4-2-3-5-19(18)22)24(30)28-17-6-8-23-21(14-17)29-25(32-23)16-10-12-27-13-11-16/h2-15H,1H3,(H,28,30)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432767 (CHEMBL2348635) Show SMILES C[C@@H](C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1)c1ccccc1 |r| Show InChI InChI=1S/C21H17N3O2/c1-14(15-5-3-2-4-6-15)20(25)23-17-7-8-19-18(13-17)24-21(26-19)16-9-11-22-12-10-16/h2-14H,1H3,(H,23,25)/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432798 (CHEMBL2348814) Show SMILES COc1ccc(OC(C)C(=O)Nc2ccc3oc(nc3c2)-c2ccncc2)cc1 Show InChI InChI=1S/C22H19N3O4/c1-14(28-18-6-4-17(27-2)5-7-18)21(26)24-16-3-8-20-19(13-16)25-22(29-20)15-9-11-23-12-10-15/h3-14H,1-2H3,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432781 (CHEMBL2348805) Show SMILES CC(Oc1ccc(Cl)c2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1cncs1 Show InChI InChI=1S/C23H16ClN3O3S/c1-13(29-19-9-7-17(24)15-4-2-3-5-16(15)19)22(28)26-14-6-8-20-18(10-14)27-23(30-20)21-11-25-12-31-21/h2-13H,1H3,(H,26,28)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432780 (CHEMBL2348806) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1nccs1 |r| Show InChI InChI=1S/C19H13Cl2N3O3S/c1-10(26-15-4-2-3-12(20)16(15)21)17(25)23-11-5-6-14-13(9-11)24-18(27-14)19-22-7-8-28-19/h2-10H,1H3,(H,23,25)/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432797 (CHEMBL2348815) Show SMILES CC(Oc1cccc(Cl)c1)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C21H16ClN3O3/c1-13(27-17-4-2-3-15(22)11-17)20(26)24-16-5-6-19-18(12-16)25-21(28-19)14-7-9-23-10-8-14/h2-13H,1H3,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432798 (CHEMBL2348814) Show SMILES COc1ccc(OC(C)C(=O)Nc2ccc3oc(nc3c2)-c2ccncc2)cc1 Show InChI InChI=1S/C22H19N3O4/c1-14(28-18-6-4-17(27-2)5-7-18)21(26)24-16-3-8-20-19(13-16)25-22(29-20)15-9-11-23-12-10-15/h3-14H,1-2H3,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432799 (CHEMBL2348813) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C21H17N3O3/c1-14(26-17-5-3-2-4-6-17)20(25)23-16-7-8-19-18(13-16)24-21(27-19)15-9-11-22-12-10-15/h2-14H,1H3,(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM40523 (2-(2,4-dichlorophenoxy)-N-(2-pyridin-4-yl-1,3-benz...) Show SMILES CC(Oc1ccc(Cl)cc1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C21H15Cl2N3O3/c1-12(28-18-4-2-14(22)10-16(18)23)20(27)25-15-3-5-19-17(11-15)26-21(29-19)13-6-8-24-9-7-13/h2-12H,1H3,(H,25,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50040481 (CHEMBL3360627) Show SMILES Clc1ccc(NC(=O)Cn2ncc3c2c2ccccc2oc3=O)cc1Cl Show InChI InChI=1S/C18H11Cl2N3O3/c19-13-6-5-10(7-14(13)20)22-16(24)9-23-17-11-3-1-2-4-15(11)26-18(25)12(17)8-21-23/h1-8H,9H2,(H,22,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
University of Houston Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum IMPDH assessed as reduction in NADH production				J Med Chem 57: 10544-50 (2014) Article DOI: 10.1021/jm501527z BindingDB Entry DOI: 10.7270/Q2XS5X1F
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432801 (CHEMBL2348811) Show SMILES CC(Oc1ccccc1Cl)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C21H16ClN3O3/c1-13(27-18-5-3-2-4-16(18)22)20(26)24-15-6-7-19-17(12-15)25-21(28-19)14-8-10-23-11-9-14/h2-13H,1H3,(H,24,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432779 (CHEMBL2348807) Show SMILES C[C@H](Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccc[nH]1 |r| Show InChI InChI=1S/C24H19N3O3/c1-15(29-21-10-4-7-16-6-2-3-8-18(16)21)23(28)26-17-11-12-22-20(14-17)27-24(30-22)19-9-5-13-25-19/h2-15,25H,1H3,(H,26,28)/t15-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432766 (CHEMBL2348636) Show SMILES C[C@@H](C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1)c1cccc(Cl)c1Cl |r| Show InChI InChI=1S/C21H15Cl2N3O2/c1-12(15-3-2-4-16(22)19(15)23)20(27)25-14-5-6-18-17(11-14)26-21(28-18)13-7-9-24-10-8-13/h2-12H,1H3,(H,25,27)/t12-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432799 (CHEMBL2348813) Show SMILES CC(Oc1ccccc1)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C21H17N3O3/c1-14(26-17-5-3-2-4-6-17)20(25)23-16-7-8-19-18(13-16)24-21(27-19)15-9-11-22-12-10-15/h2-14H,1H3,(H,23,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432787 (CHEMBL2348799) Show SMILES COc1cccc(O[C@@H](C)C(=O)Nc2ccc3oc(nc3c2)-c2ccncc2)c1OC |r| Show InChI InChI=1S/C23H21N3O5/c1-14(30-20-6-4-5-19(28-2)21(20)29-3)22(27)25-16-7-8-18-17(13-16)26-23(31-18)15-9-11-24-12-10-15/h4-14H,1-3H3,(H,25,27)/t14-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432789 (CHEMBL2348797) Show SMILES C[C@H](Oc1cccc(c1Cl)C(F)(F)F)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 |r| Show InChI InChI=1S/C22H15ClF3N3O3/c1-12(31-18-4-2-3-15(19(18)23)22(24,25)26)20(30)28-14-5-6-17-16(11-14)29-21(32-17)13-7-9-27-10-8-13/h2-12H,1H3,(H,28,30)/t12-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432795 (CHEMBL2348819) Show SMILES CC(Oc1ccc(Cl)c2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C25H18ClN3O3/c1-15(31-22-9-7-20(26)18-4-2-3-5-19(18)22)24(30)28-17-6-8-23-21(14-17)29-25(32-23)16-10-12-27-13-11-16/h2-15H,1H3,(H,28,30)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432793 (CHEMBL2348821) Show SMILES CC(C)C(Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(nc2c1)-c1ccncc1 Show InChI InChI=1S/C27H23N3O3/c1-17(2)25(32-23-9-5-7-18-6-3-4-8-21(18)23)26(31)29-20-10-11-24-22(16-20)30-27(33-24)19-12-14-28-15-13-19/h3-17,25H,1-2H3,(H,29,31)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair
Inosine-5'-monophosphate dehydrogenase (Cryptosporidium parvum)	BDBM50432773 (CHEMBL2348628) Show SMILES C[C@H](Oc1cccc(Cl)c1Cl)C(=O)Nc1ccc2nc(oc2c1)-c1cncs1 |r| Show InChI InChI=1S/C19H13Cl2N3O3S/c1-10(26-14-4-2-3-12(20)17(14)21)18(25)23-11-5-6-13-15(7-11)27-19(24-13)16-8-22-9-28-16/h2-10H,1H3,(H,23,25)/t10-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Brandeis University Curated by ChEMBL					Assay Description Inhibition of Cryptosporidium parvum N-terminal His6-tagged IMPDH-mediated NADH production expressed in Escherichia coli BL21(DE3) preincubated for 5...				J Med Chem 56: 4028-43 (2013) Article DOI: 10.1021/jm400241j BindingDB Entry DOI: 10.7270/Q2GF0VWF
					More data for this Ligand-Target Pair

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