Found 29 hits with Last Name = 'vasänge' and Initial = 'm' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50029593
(CHEMBL7162 | N-(2-(cyclohexyloxy)-4-nitrophenyl)me...)Show InChI InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of COX2 by scintillation proximity assay |
J Nat Prod 65: 1517-21 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1JNG |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390639
(CHEMBL2069712)Show InChI InChI=1S/C11H7FN2O2S3/c12-7-1-2-8-9(4-7)18-11(14-8)6-3-10(17-5-6)19(13,15)16/h1-5H,(H2,13,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 331 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390640
(CHEMBL2069713)Show InChI InChI=1S/C11H7ClN2O2S3/c12-7-1-2-8-9(4-7)18-11(14-8)6-3-10(17-5-6)19(13,15)16/h1-5H,(H2,13,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 355 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390638
(CHEMBL2069711)Show InChI InChI=1S/C11H8N2O2S3/c12-18(14,15)10-5-7(6-16-10)11-13-8-3-1-2-4-9(8)17-11/h1-6H,(H2,12,14,15) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 551 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390653
(CHEMBL2069727)Show InChI InChI=1S/C11H6ClFN2O2S3/c12-9-6(13)1-2-7-10(9)19-11(15-7)5-3-8(18-4-5)20(14,16)17/h1-4H,(H2,14,16,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 672 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM22369
(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)Show SMILES CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1 |t:11| Show InChI InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of COX2 by scintillation proximity assay |
J Nat Prod 65: 1517-21 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1JNG |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390641
(CHEMBL2069714)Show InChI InChI=1S/C12H10N2O2S3/c1-7-2-3-9-10(4-7)18-12(14-9)8-5-11(17-6-8)19(13,15)16/h2-6H,1H3,(H2,13,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390642
(CHEMBL2069715)Show SMILES NS(=O)(=O)c1cc(cs1)-c1nc2ccc(cc2s1)[N+]([O-])=O Show InChI InChI=1S/C11H7N3O4S3/c12-21(17,18)10-3-6(5-19-10)11-13-8-2-1-7(14(15)16)4-9(8)20-11/h1-5H,(H2,12,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390645
(CHEMBL2069719)Show InChI InChI=1S/C14H9N3O2S4/c18-23(19,17-14-15-5-6-20-14)12-7-9(8-21-12)13-16-10-3-1-2-4-11(10)22-13/h1-8H,(H,15,17) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM17638
(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)Show SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1 Show InChI InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of COX1 by scintillation proximity assay |
J Nat Prod 65: 1517-21 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1JNG |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390640
(CHEMBL2069713)Show InChI InChI=1S/C11H7ClN2O2S3/c12-7-1-2-8-9(4-7)18-11(14-8)6-3-10(17-5-6)19(13,15)16/h1-5H,(H2,13,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of Cdk5/p25-mediated myosin heavy chain phosphorylation in HEK293 cells |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390647
(CHEMBL2069721)Show SMILES CCOC(=O)Cc1csc(NS(=O)(=O)c2cc(cs2)-c2nc3ccccc3s2)n1 Show InChI InChI=1S/C18H15N3O4S4/c1-2-25-15(22)8-12-10-27-18(19-12)21-29(23,24)16-7-11(9-26-16)17-20-13-5-3-4-6-14(13)28-17/h3-7,9-10H,2,8H2,1H3,(H,19,21) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390648
(CHEMBL2069722)Show InChI InChI=1S/C17H13N3O2S3/c21-25(22,19-10-13-5-3-4-8-18-13)16-9-12(11-23-16)17-20-14-6-1-2-7-15(14)24-17/h1-9,11,19H,10H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 5.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390643
(CHEMBL2069716)Show InChI InChI=1S/C13H10N2O3S3/c1-7(16)8-2-3-10-11(4-8)20-13(15-10)9-5-12(19-6-9)21(14,17)18/h2-6H,1H3,(H2,14,17,18) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390654
(CHEMBL2069728)Show SMILES NS(=O)(=O)c1cc(cs1)-c1nc2cccc(-c3ccc(F)cc3)c2s1 Show InChI InChI=1S/C17H11FN2O2S3/c18-12-6-4-10(5-7-12)13-2-1-3-14-16(13)24-17(20-14)11-8-15(23-9-11)25(19,21)22/h1-9H,(H2,19,21,22) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390655
(CHEMBL2069717)Show InChI InChI=1S/C11H8N2O3S3/c14-13-19(15,16)10-5-7(6-17-10)11-12-8-3-1-2-4-9(8)18-11/h1-6,13-14H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390651
(CHEMBL2069725)Show SMILES O=S(=O)(Nc1ccc(nc1)N1CCOCC1)c1cc(cs1)-c1nc2ccccc2s1 Show InChI InChI=1S/C20H18N4O3S3/c25-30(26,23-15-5-6-18(21-12-15)24-7-9-27-10-8-24)19-11-14(13-28-19)20-22-16-3-1-2-4-17(16)29-20/h1-6,11-13,23H,7-10H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390646
(CHEMBL2069720)Show SMILES Cc1nc(NS(=O)(=O)c2cc(cs2)-c2nc3ccccc3s2)sc1C Show InChI InChI=1S/C16H13N3O2S4/c1-9-10(2)23-16(17-9)19-25(20,21)14-7-11(8-22-14)15-18-12-5-3-4-6-13(12)24-15/h3-8H,1-2H3,(H,17,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390649
(CHEMBL2069723)Show SMILES Cc1ccnc(NS(=O)(=O)c2cc(cs2)-c2nc3ccccc3s2)c1 Show InChI InChI=1S/C17H13N3O2S3/c1-11-6-7-18-15(8-11)20-25(21,22)16-9-12(10-23-16)17-19-13-4-2-3-5-14(13)24-17/h2-10H,1H3,(H,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM7459
(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)Show InChI InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 8.73E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of COX2 in LPS-stimulated bone marrow derived mast cells |
J Nat Prod 65: 1517-21 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1JNG |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390652
(CHEMBL2069726)Show SMILES OC[C@H]1CCCN1S(=O)(=O)c1cc(cs1)-c1nc2ccccc2s1 |r| Show InChI InChI=1S/C16H16N2O3S3/c19-9-12-4-3-7-18(12)24(20,21)15-8-11(10-22-15)16-17-13-5-1-2-6-14(13)23-16/h1-2,5-6,8,10,12,19H,3-4,7,9H2/t12-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390650
(CHEMBL2069724)Show InChI InChI=1S/C16H11N3O3S3/c20-12-5-3-7-17-15(12)19-25(21,22)14-8-10(9-23-14)16-18-11-4-1-2-6-13(11)24-16/h1-9,20H,(H,17,19) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50390644
(CHEMBL2069718)Show InChI InChI=1S/C13H11FN2O2S3/c14-5-6-15-21(17,18)12-7-9(8-19-12)13-16-10-3-1-2-4-11(10)20-13/h1-4,7-8,15H,5-6H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human recombinant Cdk5/p25 incubated for 15 mins by scintillation proximity assay |
Bioorg Med Chem Lett 22: 5919-23 (2012)
Article DOI: 10.1016/j.bmcl.2012.07.068 BindingDB Entry DOI: 10.7270/Q2G73FTN |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50148911
((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O |r,c:9| Show InChI InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of COX2 by scintillation proximity assay |
J Nat Prod 65: 1517-21 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1JNG |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50079577
((4aS,6aS,6bR,10S,12aR,14bS)-10-Hydroxy-2,2,6a,6b,9...)Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CCC4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2C1)C(O)=O |c:10| Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21?,22?,23-,27-,28+,29+,30-/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 8.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of COX2 by scintillation proximity assay |
J Nat Prod 65: 1517-21 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1JNG |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50164168
(1,3,4-Eugenol | 1-Hydroxy-2-methoxy-4-allylbenzene...)Show InChI InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.29E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of COX2 by scintillation proximity assay |
J Nat Prod 65: 1517-21 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1JNG |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50260180
(1,1':4',1''-Terphenyl | 1,4-Diphenylbenzene | 4-Ph...)Show InChI InChI=1S/C18H14/c1-3-7-15(8-4-1)17-11-13-18(14-12-17)16-9-5-2-6-10-16/h1-14H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.44E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of COX2 by scintillation proximity assay |
J Nat Prod 65: 1517-21 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1JNG |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM7459
(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)Show InChI InChI=1S/C15H10O6/c16-8-4-11(19)15-12(20)6-13(21-14(15)5-8)7-1-2-9(17)10(18)3-7/h1-6,16-19H | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | <3.49E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of COX2 |
J Nat Prod 65: 1517-21 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1JNG |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 1
(Homo sapiens (Human)) | BDBM22360
(2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...)Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 7.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of COX1 by scintillation proximity assay |
J Nat Prod 65: 1517-21 (2002)
BindingDB Entry DOI: 10.7270/Q2DV1JNG |
More data for this Ligand-Target Pair | |