Compile Data Set for Download or QSAR

Found 50 hits with Last Name = 'saberi' and Initial = 'mr'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aromatase (Homo sapiens (Human))	BDBM10007 (4-[(6-methoxy-1-benzofuran-2-yl)(1H-1,2,4-triazol-...) Show SMILES COc1ccc2cc(oc2c1)C(c1ccc(cc1)C#N)n1cncn1 Show InChI InChI=1S/C19H14N4O2/c1-24-16-7-6-15-8-18(25-17(15)9-16)19(23-12-21-11-22-23)14-4-2-13(10-20)3-5-14/h2-9,11-12,19H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10013 (4-[(6-Hydroxybenzofuran-2-yl)-[1,2,4]triazol-1-ylm...) Show SMILES Oc1ccc2cc(oc2c1)C(c1ccc(cc1)C#N)n1cncn1 Show InChI InChI=1S/C18H12N4O2/c19-9-12-1-3-13(4-2-12)18(22-11-20-10-21-22)17-7-14-5-6-15(23)8-16(14)24-17/h1-8,10-11,18,23H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10000 ((4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...) Show SMILES COc1ccc2cc(oc2c1)C(O)(c1ccc(F)cc1)c1cccnc1 Show InChI InChI=1S/C21H16FNO3/c1-25-18-9-4-14-11-20(26-19(14)12-18)21(24,16-3-2-10-23-13-16)15-5-7-17(22)8-6-15/h2-13,24H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10005 (1-[(4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)me...) Show SMILES COc1ccc2cc(oc2c1)C(c1ccc(Cl)cc1)n1cncn1 Show InChI InChI=1S/C18H14ClN3O2/c1-23-15-7-4-13-8-17(24-16(13)9-15)18(22-11-20-10-21-22)12-2-5-14(19)6-3-12/h2-11,18H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10001 ((4-chlorophenyl)(6-methoxy-1-benzofuran-2-yl)pyrid...) Show SMILES COc1ccc2cc(oc2c1)C(O)(c1ccc(Cl)cc1)c1cccnc1 Show InChI InChI=1S/C21H16ClNO3/c1-25-18-9-4-14-11-20(26-19(14)12-18)21(24,16-3-2-10-23-13-16)15-5-7-17(22)8-6-15/h2-13,24H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10004 (1-[(4-fluorophenyl)(6-methoxy-1-benzofuran-2-yl)me...) Show SMILES COc1ccc2cc(oc2c1)C(c1ccc(F)cc1)n1cncn1 Show InChI InChI=1S/C18H14FN3O2/c1-23-15-7-4-13-8-17(24-16(13)9-15)18(22-11-20-10-21-22)12-2-5-14(19)6-3-12/h2-11,18H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10014 (2-[(4-Nitrophenyl)-[1,2,4]triazol-1-ylmethyl]benzo...) Show SMILES Oc1ccc2cc(oc2c1)C(c1ccc(cc1)N(=O)=O)n1cncn1 Show InChI InChI=1S/C17H12N4O4/c22-14-6-3-12-7-16(25-15(12)8-14)17(20-10-18-9-19-20)11-1-4-13(5-2-11)21(23)24/h1-10,17,22H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10009 (1-[(6-Methoxybenzofuran-2-yl)-p-tolylmethyl]-1H-1,...) Show SMILES COc1ccc2cc(oc2c1)C(c1ccc(C)cc1)n1cncn1 Show InChI InChI=1S/C19H17N3O2/c1-13-3-5-14(6-4-13)19(22-12-20-11-21-22)18-9-15-7-8-16(23-2)10-17(15)24-18/h3-12,19H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10003 (1-[(6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)met...) Show SMILES COc1ccc(cc1)C(c1cc2ccc(OC)cc2o1)n1ccnc1 Show InChI InChI=1S/C20H18N2O3/c1-23-16-6-3-14(4-7-16)20(22-10-9-21-13-22)19-11-15-5-8-17(24-2)12-18(15)25-19/h3-13,20H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10006 (1-[(6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)met...) Show SMILES COc1ccc(cc1)C(c1cc2ccc(OC)cc2o1)n1cncn1 Show InChI InChI=1S/C19H17N3O3/c1-23-15-6-3-13(4-7-15)19(22-12-20-11-21-22)18-9-14-5-8-16(24-2)10-17(14)25-18/h3-12,19H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10010 (1-[(6-Methoxybenzofuran-2-yl)-(4-trifluoromethylph...) Show SMILES COc1ccc2cc(oc2c1)C(c1ccc(cc1)C(F)(F)F)n1cncn1 Show InChI InChI=1S/C19H14F3N3O2/c1-26-15-7-4-13-8-17(27-16(13)9-15)18(25-11-23-10-24-25)12-2-5-14(6-3-12)19(20,21)22/h2-11,18H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10002 ((6-Methoxybenzofuran-2-yl)-(4-methoxyphenyl)-3-pyr...) Show SMILES COc1ccc(cc1)C(O)(c1cc2ccc(OC)cc2o1)c1cccnc1 Show InChI InChI=1S/C22H19NO4/c1-25-18-9-6-16(7-10-18)22(24,17-4-3-11-23-14-17)21-12-15-5-8-19(26-2)13-20(15)27-21/h3-14,24H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308952 (4-Methyl-6-({3-[(4-methylpiperidino)carbonyl]-benz...) Show SMILES CC1CCN(CC1)C(=O)c1cccc(COc2ccc3[nH]c(=O)cc(C)c3c2)c1 Show InChI InChI=1S/C24H26N2O3/c1-16-8-10-26(11-9-16)24(28)19-5-3-4-18(13-19)15-29-20-6-7-22-21(14-20)17(2)12-23(27)25-22/h3-7,12-14,16H,8-11,15H2,1-2H3,(H,25,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10015 (2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1...) Show SMILES CC(C)(C#N)c1cc(Cn2cncn2)cc(c1)C(C)(C)C#N Show InChI InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10015 (2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1...) Show SMILES CC(C)(C#N)c1cc(Cn2cncn2)cc(c1)C(C)(C)C#N Show InChI InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.				J Enzyme Inhib Med Chem 20: 135-41 (2005) Article DOI: 10.1080/14756360400015256 BindingDB Entry DOI: 10.7270/Q2B56H9Z
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10008 (1-[(6-Methoxybenzofuran-2-yl)-(4-nitrophenyl)methy...) Show SMILES COc1ccc2cc(oc2c1)C(c1ccc(cc1)N(=O)=O)n1cncn1 Show InChI InChI=1S/C18H14N4O4/c1-25-15-7-4-13-8-17(26-16(13)9-15)18(21-11-19-10-20-21)12-2-5-14(6-3-12)22(23)24/h2-11,18H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308954 (4-Methyl-6-{[3-(tetrahydro-1H-1-pyrrolylcarbonyl)-...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCCC3)cc12 Show InChI InChI=1S/C22H22N2O3/c1-15-11-21(25)23-20-8-7-18(13-19(15)20)27-14-16-5-4-6-17(12-16)22(26)24-9-2-3-10-24/h4-8,11-13H,2-3,9-10,14H2,1H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308951 (4-Methyl-6-{[3-(piperidinocarbonyl)benzyl]oxy}-1,2...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCCCC3)cc12 Show InChI InChI=1S/C23H24N2O3/c1-16-12-22(26)24-21-9-8-19(14-20(16)21)28-15-17-6-5-7-18(13-17)23(27)25-10-3-2-4-11-25/h5-9,12-14H,2-4,10-11,15H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308949 (1-(3-{[(4-Methyl-2-oxo-1,2-dihydro-6-quinolinyl)ox...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCC(CC3)C(O)=O)cc12 Show InChI InChI=1S/C24H24N2O5/c1-15-11-22(27)25-21-6-5-19(13-20(15)21)31-14-16-3-2-4-18(12-16)23(28)26-9-7-17(8-10-26)24(29)30/h2-6,11-13,17H,7-10,14H2,1H3,(H,25,27)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308950 (6-({3-[(4-Hydroxypiperidino)carbonyl]benzyl}oxy)-4...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCC(O)CC3)cc12 Show InChI InChI=1S/C23H24N2O4/c1-15-11-22(27)24-21-6-5-19(13-20(15)21)29-14-16-3-2-4-17(12-16)23(28)25-9-7-18(26)8-10-25/h2-6,11-13,18,26H,7-10,14H2,1H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308948 (4-Methyl-6-(3-[(4-oxopiperidino)carbonyl]benzyloxy...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCC(=O)CC3)cc12 Show InChI InChI=1S/C23H22N2O4/c1-15-11-22(27)24-21-6-5-19(13-20(15)21)29-14-16-3-2-4-17(12-16)23(28)25-9-7-18(26)8-10-25/h2-6,11-13H,7-10,14H2,1H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308954 (4-Methyl-6-{[3-(tetrahydro-1H-1-pyrrolylcarbonyl)-...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCCC3)cc12 Show InChI InChI=1S/C22H22N2O3/c1-15-11-21(25)23-20-8-7-18(13-19(15)20)27-14-16-5-4-6-17(12-16)22(26)24-9-2-3-10-24/h4-8,11-13H,2-3,9-10,14H2,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10011 (1-[(4-ethylphenyl)(6-methoxy-1-benzofuran-2-yl)met...) Show SMILES CCc1ccc(cc1)C(c1cc2ccc(OC)cc2o1)n1cncn1 Show InChI InChI=1S/C20H19N3O2/c1-3-14-4-6-15(7-5-14)20(23-13-21-12-22-23)19-10-16-8-9-17(24-2)11-18(16)25-19/h4-13,20H,3H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308948 (4-Methyl-6-(3-[(4-oxopiperidino)carbonyl]benzyloxy...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCC(=O)CC3)cc12 Show InChI InChI=1S/C23H22N2O4/c1-15-11-22(27)24-21-6-5-19(13-20(15)21)29-14-16-3-2-4-17(12-16)23(28)25-9-7-18(26)8-10-25/h2-6,11-13H,7-10,14H2,1H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308949 (1-(3-{[(4-Methyl-2-oxo-1,2-dihydro-6-quinolinyl)ox...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCC(CC3)C(O)=O)cc12 Show InChI InChI=1S/C24H24N2O5/c1-15-11-22(27)25-21-6-5-19(13-20(15)21)31-14-16-3-2-4-18(12-16)23(28)26-9-7-17(8-10-26)24(29)30/h2-6,11-13,17H,7-10,14H2,1H3,(H,25,27)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM86018 (Pyridylmethanol, 8f) Show SMILES COc1ccc(cc1)C(O)(c1cc2ccccc2o1)c1cccnc1 Show InChI InChI=1S/C21H17NO3/c1-24-18-10-8-16(9-11-18)21(23,17-6-4-12-22-14-17)20-13-15-5-2-3-7-19(15)25-20/h2-14,23H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.				J Enzyme Inhib Med Chem 20: 135-41 (2005) Article DOI: 10.1080/14756360400015256 BindingDB Entry DOI: 10.7270/Q2B56H9Z
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308953 (4-Methyl-6-{[3-(morpholinocarbonyl)benzyl]oxy}-1,2...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCOCC3)cc12 Show InChI InChI=1S/C22H22N2O4/c1-15-11-21(25)23-20-6-5-18(13-19(15)20)28-14-16-3-2-4-17(12-16)22(26)24-7-9-27-10-8-24/h2-6,11-13H,7-10,14H2,1H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308950 (6-({3-[(4-Hydroxypiperidino)carbonyl]benzyl}oxy)-4...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCC(O)CC3)cc12 Show InChI InChI=1S/C23H24N2O4/c1-15-11-22(27)24-21-6-5-19(13-20(15)21)29-14-16-3-2-4-17(12-16)23(28)25-9-7-18(26)8-10-25/h2-6,11-13,18,26H,7-10,14H2,1H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308946 (4-Methyl-6-({3-[(4-ethylpiperazino)carbonyl]-benzy...) Show SMILES CCN1CCN(CC1)C(=O)c1cccc(COc2ccc3[nH]c(=O)cc(C)c3c2)c1 Show InChI InChI=1S/C24H27N3O3/c1-3-26-9-11-27(12-10-26)24(29)19-6-4-5-18(14-19)16-30-20-7-8-22-21(15-20)17(2)13-23(28)25-22/h4-8,13-15H,3,9-12,16H2,1-2H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM10012 (2-[(4-Chlorophenyl)-[1,2,4]triazol-1-ylmethyl]benz...) Show SMILES Oc1ccc2cc(oc2c1)C(c1ccc(Cl)cc1)n1cncn1 Show InChI InChI=1S/C17H12ClN3O2/c18-13-4-1-11(2-5-13)17(21-10-19-9-20-21)16-7-12-3-6-14(22)8-15(12)23-16/h1-10,17,22H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+3	n/a	n/a	n/a	n/a	7.4	37
Cardiff University					Assay Description The enzyme activity was assayed by measuring the 3H-labeled H2O formed from [1,2,6,7-3H ]androstenedione / androstenedione during aromatization. Afte...				J Med Chem 49: 1016-22 (2006) Article DOI: 10.1021/jm0508282 BindingDB Entry DOI: 10.7270/Q2NK3C76
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308953 (4-Methyl-6-{[3-(morpholinocarbonyl)benzyl]oxy}-1,2...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCOCC3)cc12 Show InChI InChI=1S/C22H22N2O4/c1-15-11-21(25)23-20-6-5-18(13-19(15)20)28-14-16-3-2-4-17(12-16)22(26)24-7-9-27-10-8-24/h2-6,11-13H,7-10,14H2,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308952 (4-Methyl-6-({3-[(4-methylpiperidino)carbonyl]-benz...) Show SMILES CC1CCN(CC1)C(=O)c1cccc(COc2ccc3[nH]c(=O)cc(C)c3c2)c1 Show InChI InChI=1S/C24H26N2O3/c1-16-8-10-26(11-9-16)24(28)19-5-3-4-18(13-19)15-29-20-6-7-22-21(14-20)17(2)12-23(27)25-22/h3-7,12-14,16H,8-11,15H2,1-2H3,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308947 (6-[(3-{[4-(2-Hydroxyethyl)piperazino]carbonyl}-ben...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCN(CCO)CC3)cc12 Show InChI InChI=1S/C24H27N3O4/c1-17-13-23(29)25-22-6-5-20(15-21(17)22)31-16-18-3-2-4-19(14-18)24(30)27-9-7-26(8-10-27)11-12-28/h2-6,13-15,28H,7-12,16H2,1H3,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.65E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308951 (4-Methyl-6-{[3-(piperidinocarbonyl)benzyl]oxy}-1,2...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCCCC3)cc12 Show InChI InChI=1S/C23H24N2O3/c1-16-12-22(26)24-21-9-8-19(14-20(16)21)28-15-17-6-5-7-18(13-17)23(27)25-10-3-2-4-11-25/h5-9,12-14H,2-4,10-11,15H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308945 (4-Methyl-6-({3-[(4-methylpiperazino)carbonyl]-benz...) Show SMILES CN1CCN(CC1)C(=O)c1cccc(COc2ccc3[nH]c(=O)cc(C)c3c2)c1 Show InChI InChI=1S/C23H25N3O3/c1-16-12-22(27)24-21-7-6-19(14-20(16)21)29-15-17-4-3-5-18(13-17)23(28)26-10-8-25(2)9-11-26/h3-7,12-14H,8-11,15H2,1-2H3,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308946 (4-Methyl-6-({3-[(4-ethylpiperazino)carbonyl]-benzy...) Show SMILES CCN1CCN(CC1)C(=O)c1cccc(COc2ccc3[nH]c(=O)cc(C)c3c2)c1 Show InChI InChI=1S/C24H27N3O3/c1-3-26-9-11-27(12-10-26)24(29)19-6-4-5-18(14-19)16-30-20-7-8-22-21(15-20)17(2)13-23(28)25-22/h4-8,13-15H,3,9-12,16H2,1-2H3,(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM86017 (Pyridylmethanol, 8e) Show SMILES OC(c1cc2ccccc2o1)(c1cccnc1)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H13Cl2NO2/c21-15-7-8-16(17(22)11-15)20(24,14-5-3-9-23-12-14)19-10-13-4-1-2-6-18(13)25-19/h1-12,24H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.				J Enzyme Inhib Med Chem 20: 135-41 (2005) Article DOI: 10.1080/14756360400015256 BindingDB Entry DOI: 10.7270/Q2B56H9Z
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308947 (6-[(3-{[4-(2-Hydroxyethyl)piperazino]carbonyl}-ben...) Show SMILES Cc1cc(=O)[nH]c2ccc(OCc3cccc(c3)C(=O)N3CCN(CCO)CC3)cc12 Show InChI InChI=1S/C24H27N3O4/c1-17-13-23(29)25-22-6-5-20(15-21(17)22)31-16-18-3-2-4-19(14-18)24(30)27-9-7-26(8-10-27)11-12-28/h2-6,13-15,28H,7-12,16H2,1H3,(H,25,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50308956 (6-(3-(4-methylpiperazine-1-carbonyl)benzyloxy)quin...) Show SMILES CN1CCN(CC1)C(=O)c1cccc(COc2ccc3[nH]c(=O)ccc3c2)c1 Show InChI InChI=1S/C22H23N3O3/c1-24-9-11-25(12-10-24)22(27)18-4-2-3-16(13-18)15-28-19-6-7-20-17(14-19)5-8-21(26)23-20/h2-8,13-14H,9-12,15H2,1H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308945 (4-Methyl-6-({3-[(4-methylpiperazino)carbonyl]-benz...) Show SMILES CN1CCN(CC1)C(=O)c1cccc(COc2ccc3[nH]c(=O)cc(C)c3c2)c1 Show InChI InChI=1S/C23H25N3O3/c1-16-12-22(27)24-21-7-6-19(14-20(16)21)29-15-17-4-3-5-18(13-17)23(28)26-10-8-25(2)9-11-26/h3-7,12-14H,8-11,15H2,1-2H3,(H,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM86014 (Pyridylmethanol, 8b) Show SMILES OC(c1cc2ccccc2o1)(c1ccc(Cl)cc1)c1cccnc1 Show InChI InChI=1S/C20H14ClNO2/c21-17-9-7-15(8-10-17)20(23,16-5-3-11-22-13-16)19-12-14-4-1-2-6-18(14)24-19/h1-13,23H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.				J Enzyme Inhib Med Chem 20: 135-41 (2005) Article DOI: 10.1080/14756360400015256 BindingDB Entry DOI: 10.7270/Q2B56H9Z
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50308956 (6-(3-(4-methylpiperazine-1-carbonyl)benzyloxy)quin...) Show SMILES CN1CCN(CC1)C(=O)c1cccc(COc2ccc3[nH]c(=O)ccc3c2)c1 Show InChI InChI=1S/C22H23N3O3/c1-24-9-11-25(12-10-24)22(27)18-4-2-3-16(13-18)15-28-19-6-7-20-17(14-19)5-8-21(26)23-20/h2-8,13-14H,9-12,15H2,1H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM86013 (Pyridylmethanol, 8a) Show SMILES OC(c1cc2ccccc2o1)(c1ccc(F)cc1)c1cccnc1 Show InChI InChI=1S/C20H14FNO2/c21-17-9-7-15(8-10-17)20(23,16-5-3-11-22-13-16)19-12-14-4-1-2-6-18(14)24-19/h1-13,23H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.				J Enzyme Inhib Med Chem 20: 135-41 (2005) Article DOI: 10.1080/14756360400015256 BindingDB Entry DOI: 10.7270/Q2B56H9Z
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50016980 (6-(4-(3,4-dimethoxybenzoyl)piperazin-1-yl)-3,4-dih...) Show SMILES COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C22H25N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,13-14H,4,8-12H2,1-2H3,(H,23,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3A by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM86016 (Pyridylmethanol, 8d) Show SMILES OC(c1cc2ccccc2o1)(c1ccc(I)cc1)c1cccnc1 Show InChI InChI=1S/C20H14INO2/c21-17-9-7-15(8-10-17)20(23,16-5-3-11-22-13-16)19-12-14-4-1-2-6-18(14)24-19/h1-13,23H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.				J Enzyme Inhib Med Chem 20: 135-41 (2005) Article DOI: 10.1080/14756360400015256 BindingDB Entry DOI: 10.7270/Q2B56H9Z
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50016980 (6-(4-(3,4-dimethoxybenzoyl)piperazin-1-yl)-3,4-dih...) Show SMILES COc1ccc(cc1OC)C(=O)N1CCN(CC1)c1ccc2NC(=O)CCc2c1 Show InChI InChI=1S/C22H25N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,13-14H,4,8-12H2,1-2H3,(H,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Islamic Azad University Curated by ChEMBL					Assay Description Inhibition of human PDE3B by fluorescence microplate reader				Bioorg Med Chem 18: 855-62 (2010) Article DOI: 10.1016/j.bmc.2009.11.044 BindingDB Entry DOI: 10.7270/Q2Q81F13
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9460 (3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...) Show SMILES CCC1(CCC(=O)NC1=O)c1ccc(N)cc1 Show InChI InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.				J Enzyme Inhib Med Chem 20: 135-41 (2005) Article DOI: 10.1080/14756360400015256 BindingDB Entry DOI: 10.7270/Q2B56H9Z
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM86015 (Pyridylmethanol, 8c) Show SMILES OC(c1cc2ccccc2o1)(c1ccc(Br)cc1)c1cccnc1 Show InChI InChI=1S/C20H14BrNO2/c21-17-9-7-15(8-10-17)20(23,16-5-3-11-22-13-16)19-12-14-4-1-2-6-18(14)24-19/h1-13,23H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.51E+4	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.				J Enzyme Inhib Med Chem 20: 135-41 (2005) Article DOI: 10.1080/14756360400015256 BindingDB Entry DOI: 10.7270/Q2B56H9Z
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM86020 (Pyridylmethanol, 9b) Show SMILES COc1ccc(cc1)C(O)(c1ccco1)c1cccnc1 Show InChI InChI=1S/C17H15NO3/c1-20-15-8-6-13(7-9-15)17(19,16-5-3-11-21-16)14-4-2-10-18-12-14/h2-12,19H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.				J Enzyme Inhib Med Chem 20: 135-41 (2005) Article DOI: 10.1080/14756360400015256 BindingDB Entry DOI: 10.7270/Q2B56H9Z
					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM86019 (Pyridylmethanol, 9a) Show SMILES OC(c1ccco1)(c1ccc(Cl)cc1)c1cccnc1 Show InChI InChI=1S/C16H12ClNO2/c17-14-7-5-12(6-8-14)16(19,15-4-2-10-20-15)13-3-1-9-18-11-13/h1-11,19H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	37
Cardiff University					Assay Description The classical 3H2O assay was used to measure the effect of the inhibitor compounds on aromatase activity using human placental microsomes.				J Enzyme Inhib Med Chem 20: 135-41 (2005) Article DOI: 10.1080/14756360400015256 BindingDB Entry DOI: 10.7270/Q2B56H9Z
					More data for this Ligand-Target Pair