Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50180955![]() (CHEMBL3818617) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER Pharma AG Curated by ChEMBL | Assay Description Competitive inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using varying levels of Btn-Ahx-GSRAHSSHLKSKK... | J Med Chem 59: 4578-600 (2016) Article DOI: 10.1021/acs.jmedchem.5b01890 BindingDB Entry DOI: 10.7270/Q2RN39S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM50180955![]() (CHEMBL3818617) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
BAYER Pharma AG Curated by ChEMBL | Assay Description Uncompetitive inhibition of full length 6xHis-tagged SMYD2 (unknown origin) expressed in Escherichia coli using fixed levels of Btn-Ahx-GSRAHSSHLKSKK... | J Med Chem 59: 4578-600 (2016) Article DOI: 10.1021/acs.jmedchem.5b01890 BindingDB Entry DOI: 10.7270/Q2RN39S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254841![]() (US9487554, 28) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254826![]() (US9487554, 13) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254825![]() (US9487554, 12) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254815![]() (US9487554, 2) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM258453![]() (US9512169, 7) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | 7.0 | 22 |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtiter plat... | US Patent US9512169 (2016) BindingDB Entry DOI: 10.7270/Q24B3081 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254814![]() (US9487554, 1) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254815![]() (US9487554, 2) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254825![]() (US9487554, 12) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254824![]() (US9487554, 11) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254826![]() (US9487554, 13) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254836![]() (US9487554, 23) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254814![]() (US9487554, 1) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254824![]() (US9487554, 11) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM258457![]() (US9512169, 11) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | 7.0 | 22 |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtiter plat... | US Patent US9512169 (2016) BindingDB Entry DOI: 10.7270/Q24B3081 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254842![]() (US9487554, 29) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM283143![]() ((2R)N-[1-{N′-cyano-N-[3-(difluorometho...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.64 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description For the detection of SMYD2 cellular methylation activity an In Cell Western (ICW) assay was established. This assay allows rapid processing of multip... | US Patent US10023539 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM258456![]() (US9512169, 10) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | 7.0 | 22 |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtiter plat... | US Patent US9512169 (2016) BindingDB Entry DOI: 10.7270/Q24B3081 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM258459![]() (US9512169, 13) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.80 | n/a | n/a | n/a | n/a | 7.0 | 22 |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtiter plat... | US Patent US9512169 (2016) BindingDB Entry DOI: 10.7270/Q24B3081 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254818![]() (US9487554, 5) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264475![]() (17-oxooestra-1,3,5(10)-triene-3,11a-diyl diacetate...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264509![]() (17-(5-fluoropyridin-3-yl)-N?[(R)-2-hydroxypropyl]o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264504![]() (N?[(S)-2,3-dihydroxypropyl]-17-(5-fluoropyridin-3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM258458![]() (US9512169, 12) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | 7.0 | 22 |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtiter plat... | US Patent US9512169 (2016) BindingDB Entry DOI: 10.7270/Q24B3081 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254835![]() (US9487554, 22) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.20 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254818![]() (US9487554, 5) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254829![]() (US9487554, 16) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254823![]() (US9487554, 10) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264508![]() (17-(5-fluoropyridin-3-yl)-N-[2-(methylsulphinyl)et...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264493![]() (17-(5-fluoropyridin-3-yl)-N-(1H-tetrazol-5-ylmethy...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264498![]() (17-(5-fluoropyridin-3-yl)-N-[3-(methylamino)-3-oxo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264497![]() (N-(3-amino-3-oxopropyl)-17-(5-fluoropyridin-3-yl)o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264510![]() (N-ethyl-17-(5-fluoropyridin-3-yl)oestra-1,3,5(10),...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264492![]() (17-(5-fluoropyridin-3-yl)-N-[2-(1H-tetrazol-5-yl)e...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254837![]() (US9487554, 24) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.30 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM283194![]() (Rac-N-[1-(N′-cyano-N-{5-(difluoromethoxy)-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 5.55 | n/a | n/a | n/a | n/a | 9.0 | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea... | US Patent US10023539 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264505![]() (17-(5-fluoropyridin-3-yl)-N-(3-hydroxypropyl)-N-me...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264516![]() (17-(5-fluoropyridin-3-yl)-N?[(S)-2-hydroxypropyl]o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264515![]() (17-(5-fluoropyridin-3-yl)-N?[(S)-2-hydroxypropyl]o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264507![]() (N?[(R)-2,3-dihydroxypropyl]-17-(5-fluoropyridin-3-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264472![]() (17-(pyridin-3-yl)oestra-1,3,5(10),16-tetraene-3-ca...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-lysine methyltransferase SMYD2 (Homo sapiens (Human)) | BDBM283173![]() (N-[1-{N′-cyano-N-[2-methoxy-5-(trifluorometh...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.65 | n/a | n/a | n/a | n/a | 9.0 | n/a |
Bayer Pharma Aktiengesellschaft US Patent | Assay Description SMYD2 inhibitory activities of the compounds described in the present invention were quantified using a scintillation proximity assay (SPA) which mea... | US Patent US10023539 (2018) BindingDB Entry DOI: 10.7270/Q2MG7RKD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254821![]() (US9487554, 8) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254829![]() (US9487554, 16) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254828![]() (US9487554, 15) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3 (Homo sapiens (Human)) | BDBM264513![]() (17-(5-fluoropyridin-3-yl)-N-[(3-methyloxetan-3-yl)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 7 | n/a | n/a | n/a | n/a | 7.0 | n/a |
BAYER PHARMA AKTIENGESELLSCHAFT US Patent | Assay Description For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat... | US Patent US9714266 (2017) BindingDB Entry DOI: 10.7270/Q2ZG6V7W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254828![]() (US9487554, 15) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254823![]() (US9487554, 10) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aldo-keto reductase family 1 member C3/Glutathione S-transferase P (Homo sapiens (Human)) | BDBM254843![]() (US9487554, 30) | PDB UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 7.30 | n/a | n/a | n/a | n/a | 7.0 | n/a |
Bayer Intellectual Property GmbH; Bayer Pharma Aktiengesellschaft US Patent | Assay Description Essentially, the enzyme activity is measured by quantification of the Coumberol from Coumberone (Halim, M., Yee, D. J., and Sames, D., J. AM. CHEM. S... | US Patent US9487554 (2016) BindingDB Entry DOI: 10.7270/Q2KK99Q9 | |||||||||||
More data for this Ligand-Target Pair |
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