Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (Homo sapiens (Human)) | BDBM16047 ((4S)-4-[(2S)-2-[(2R,4S,5S)-5-[(2S)-2-[(2S)-2-[(4S)...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of BACE1 | Bioorg Med Chem Lett 19: 6770-4 (2009) Article DOI: 10.1016/j.bmcl.2009.09.103 BindingDB Entry DOI: 10.7270/Q2VT1T2V | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50311847 (2-(3-(2-(2-hydroxy-5-nitrobenzoyl)hydrazono)-2-oxo...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of human recombinant BACE1 at 100 uM | Bioorg Med Chem Lett 19: 6770-4 (2009) Article DOI: 10.1016/j.bmcl.2009.09.103 BindingDB Entry DOI: 10.7270/Q2VT1T2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50311848 (CHEMBL1080086 | N-cyclohexyl-2-(3-(2-(2-hydroxy-5-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of human recombinant BACE1 at 100 uM | Bioorg Med Chem Lett 19: 6770-4 (2009) Article DOI: 10.1016/j.bmcl.2009.09.103 BindingDB Entry DOI: 10.7270/Q2VT1T2V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 2 (Homo sapiens (Human)) | BDBM50427058 (CHEMBL2322538) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427058 (CHEMBL2322538) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.69E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 2 (Homo sapiens (Human)) | BDBM50427056 (CHEMBL2322539) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427057 (CHEMBL2322537) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.35E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427053 (CHEMBL2322541) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.89E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427045 (CHEMBL2322830) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427056 (CHEMBL2322539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427055 (CHEMBL2322536) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427055 (CHEMBL2322536) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427051 (CHEMBL2322534) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427048 (CHEMBL2322831) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427047 (CHEMBL2322832) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427049 (CHEMBL2322829) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427052 (CHEMBL2322533) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427050 (CHEMBL2322542) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 2 (Homo sapiens (Human)) | BDBM50427057 (CHEMBL2322537) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427054 (CHEMBL2322540) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 2 (Homo sapiens (Human)) | BDBM50427055 (CHEMBL2322536) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.94E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 2 (Homo sapiens (Human)) | BDBM50427055 (CHEMBL2322536) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 2 (Homo sapiens (Human)) | BDBM50427054 (CHEMBL2322540) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.46E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 2 (Homo sapiens (Human)) | BDBM50427053 (CHEMBL2322541) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.19E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM50427046 (CHEMBL2322833) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.23E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE1 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 2 (Homo sapiens (Human)) | BDBM50427045 (CHEMBL2322830) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 2 (Homo sapiens (Human)) | BDBM50427046 (CHEMBL2322833) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds Curated by ChEMBL | Assay Description Inhibition of recombinant BACE2 (unknown origin) using FAM-SEVNLDAEFK-TAMRA as substrate incubated for 30 mins prior to substrate addition by fluorim... | J Med Chem 56: 1843-52 (2013) Article DOI: 10.1021/jm301127x BindingDB Entry DOI: 10.7270/Q2XG9SG1 | |||||||||||
More data for this Ligand-Target Pair |