Compile Data Set for Download or QSAR

Found 197 hits with Last Name = 'vilaseca' and Initial = 'p'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035089 (CHEMBL3338297) Show SMILES Cc1noc(C2CC2)c1Cc1cc(ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(F)(F)F Show InChI InChI=1S/C25H22F3N3O3/c1-13-3-7-19-17(11-22(32)33)12-31(24(19)29-13)21-8-6-18(25(26,27)28)9-16(21)10-20-14(2)30-34-23(20)15-4-5-15/h3,6-9,12,15H,4-5,10-11H2,1-2H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035039 (CHEMBL3338270) Show SMILES Cc1nnc(C)n1Cc1cc(C)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C22H23N5O2/c1-13-5-8-20(18(9-13)12-26-15(3)24-25-16(26)4)27-11-17(10-21(28)29)19-7-6-14(2)23-22(19)27/h5-9,11H,10,12H2,1-4H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035088 (CHEMBL3338296) Show SMILES Cc1noc(C2CC2)c1Cc1cc(F)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C24H22FN3O3/c1-13-3-7-19-17(11-22(29)30)12-28(24(19)26-13)21-8-6-18(25)9-16(21)10-20-14(2)27-31-23(20)15-4-5-15/h3,6-9,12,15H,4-5,10-11H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034956 (CHEMBL3338150) Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)n2cccnc12)C(F)(F)F)C(=O)C1CC1 Show InChI InChI=1S/C23H22F3N3O3/c1-2-28(22(32)14-4-5-14)13-15-10-16(23(24,25)26)6-7-18(15)19-11-17(12-20(30)31)29-9-3-8-27-21(19)29/h3,6-11,14H,2,4-5,12-13H2,1H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor in human eosinophil assessed as inhibition of PGD2-induced cell shape change				Bioorg Med Chem Lett 24: 5118-22 (2014) Article DOI: 10.1016/j.bmcl.2014.09.005 BindingDB Entry DOI: 10.7270/Q2H70HFQ
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034956 (CHEMBL3338150) Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)n2cccnc12)C(F)(F)F)C(=O)C1CC1 Show InChI InChI=1S/C23H22F3N3O3/c1-2-28(22(32)14-4-5-14)13-15-10-16(23(24,25)26)6-7-18(15)19-11-17(12-20(30)31)29-9-3-8-27-21(19)29/h3,6-11,14H,2,4-5,12-13H2,1H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change preincubated for 10 mins wi...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035038 (CHEMBL3338269) Show SMILES Cc1noc(C)c1Cc1cc(F)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C22H20FN3O3/c1-12-4-6-18-16(10-21(27)28)11-26(22(18)24-12)20-7-5-17(23)8-15(20)9-19-13(2)25-29-14(19)3/h4-8,11H,9-10H2,1-3H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035088 (CHEMBL3338296) Show SMILES Cc1noc(C2CC2)c1Cc1cc(F)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C24H22FN3O3/c1-13-3-7-19-17(11-22(29)30)12-28(24(19)26-13)21-8-6-18(25)9-16(21)10-20-14(2)27-31-23(20)15-4-5-15/h3,6-9,12,15H,4-5,10-11H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035077 (CHEMBL3338285) Show SMILES Cc1nnc(C2CC2)n1Cc1cc(ccc1-c1cn(CC(O)=O)c2ccc(F)cc12)C(F)(F)F Show InChI InChI=1S/C24H20F4N4O2/c1-13-29-30-23(14-2-3-14)32(13)10-15-8-16(24(26,27)28)4-6-18(15)20-11-31(12-22(33)34)21-7-5-17(25)9-19(20)21/h4-9,11,14H,2-3,10,12H2,1H3,(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035079 (CHEMBL3338287) Show SMILES Cc1nnc(Cc2ccccc2)n1Cc1cc(Cl)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C27H24ClN5O2/c1-17-8-10-23-20(14-26(34)35)15-33(27(23)29-17)24-11-9-22(28)13-21(24)16-32-18(2)30-31-25(32)12-19-6-4-3-5-7-19/h3-11,13,15H,12,14,16H2,1-2H3,(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50154763 (CHEMBL3774415) Show SMILES COc1ccc(c(Cc2c(C)n(CC(O)=O)c3CCCC(=O)c23)c1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C25H24FNO6S/c1-15-20(25-21(4-3-5-22(25)28)27(15)14-24(29)30)13-16-12-18(33-2)8-11-23(16)34(31,32)19-9-6-17(26)7-10-19/h6-12H,3-5,13-14H2,1-2H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter				Eur J Med Chem 113: 102-33 (2016) Article DOI: 10.1016/j.ejmech.2016.02.023 BindingDB Entry DOI: 10.7270/Q2K64KXM
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50154805 (CHEMBL3775213) Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c2c(CCCC2=O)n1CC(O)=O Show InChI InChI=1S/C24H22FNO5S/c1-15-19(24-20(6-4-7-21(24)27)26(15)14-23(28)29)13-16-5-2-3-8-22(16)32(30,31)18-11-9-17(25)10-12-18/h2-3,5,8-12H,4,6-7,13-14H2,1H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter				Eur J Med Chem 113: 102-33 (2016) Article DOI: 10.1016/j.ejmech.2016.02.023 BindingDB Entry DOI: 10.7270/Q2K64KXM
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035086 (CHEMBL3338294) Show SMILES Cc1noc(C2CC2)c1Cc1cc(ccc1-c1cc(CC(O)=O)c2ccc(C)nn12)C(F)(F)F Show InChI InChI=1S/C25H22F3N3O3/c1-13-3-8-21-17(12-23(32)33)11-22(31(21)29-13)19-7-6-18(25(26,27)28)9-16(19)10-20-14(2)30-34-24(20)15-4-5-15/h3,6-9,11,15H,4-5,10,12H2,1-2H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035091 (CHEMBL3338299) Show SMILES Cc1ccc2c(CC(O)=O)cn(-c3ccc(cc3Cc3c(noc3C3CC3)C3CC3)C(F)(F)F)c2n1 Show InChI InChI=1S/C27H24F3N3O3/c1-14-2-8-20-18(12-23(34)35)13-33(26(20)31-14)22-9-7-19(27(28,29)30)10-17(22)11-21-24(15-3-4-15)32-36-25(21)16-5-6-16/h2,7-10,13,15-16H,3-6,11-12H2,1H3,(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035093 (CHEMBL3338301) Show SMILES Cc1noc(Cc2ccccc2)c1Cc1cc(Cl)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C28H24ClN3O3/c1-17-8-10-23-21(15-27(33)34)16-32(28(23)30-17)25-11-9-22(29)13-20(25)14-24-18(2)31-35-26(24)12-19-6-4-3-5-7-19/h3-11,13,16H,12,14-15H2,1-2H3,(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035030 (CHEMBL3343128) Show SMILES Cc1ccc2c(CC(O)=O)cn(-c3ccc(cc3CN(CCOc3ccccc3)C(=O)C3CC3)C(F)(F)F)c2n1 Show InChI InChI=1S/C30H28F3N3O4/c1-19-7-11-25-21(16-27(37)38)18-36(28(25)34-19)26-12-10-23(30(31,32)33)15-22(26)17-35(29(39)20-8-9-20)13-14-40-24-5-3-2-4-6-24/h2-7,10-12,15,18,20H,8-9,13-14,16-17H2,1H3,(H,37,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035031 (CHEMBL3343129) Show SMILES COCCN(Cc1cc(ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(F)(F)F)C(=O)C1CC1 Show InChI InChI=1S/C25H26F3N3O4/c1-15-3-7-20-17(12-22(32)33)14-31(23(20)29-15)21-8-6-19(25(26,27)28)11-18(21)13-30(9-10-35-2)24(34)16-4-5-16/h3,6-8,11,14,16H,4-5,9-10,12-13H2,1-2H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035034 (CHEMBL3338261) Show SMILES Cc1ccc2c(CC(O)=O)cn(-c3ccc(cc3CSC(C)(C)C)C(=O)NCCc3ccccc3)c2n1 Show InChI InChI=1S/C30H33N3O3S/c1-20-10-12-25-23(17-27(34)35)18-33(28(25)32-20)26-13-11-22(16-24(26)19-37-30(2,3)4)29(36)31-15-14-21-8-6-5-7-9-21/h5-13,16,18H,14-15,17,19H2,1-4H3,(H,31,36)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035074 (CHEMBL3338282) Show SMILES Cc1cnn(CC2CC2)c1Cc1cc(C)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C26H28N4O2/c1-16-4-9-23(20(10-16)11-24-17(2)13-27-30(24)14-19-6-7-19)29-15-21(12-25(31)32)22-8-5-18(3)28-26(22)29/h4-5,8-10,13,15,19H,6-7,11-12,14H2,1-3H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035103 (CHEMBL3337464) Show SMILES Cc1c(-c2cccc3CN(CCc23)S(C)(=O)=O)c2cc(F)ccc2n1CC(O)=O |(5.67,-9.17,;5.99,-10.68,;7.4,-11.31,;8.74,-10.54,;10.07,-11.31,;11.42,-10.54,;11.41,-8.98,;10.07,-8.23,;10.07,-6.7,;8.74,-5.93,;7.42,-6.7,;7.41,-8.23,;8.74,-8.99,;8.74,-4.38,;10.09,-3.62,;7.2,-4.37,;7.98,-3.04,;7.24,-12.84,;8.26,-13.97,;7.79,-15.43,;8.83,-16.57,;6.29,-15.75,;5.26,-14.61,;5.74,-13.15,;4.96,-11.82,;3.42,-11.67,;2.52,-12.92,;.98,-12.77,;3.15,-14.33,)| Show InChI InChI=1S/C21H21FN2O4S/c1-13-21(18-10-15(22)6-7-19(18)24(13)12-20(25)26)17-5-3-4-14-11-23(29(2,27)28)9-8-16(14)17/h3-7,10H,8-9,11-12H2,1-2H3,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035074 (CHEMBL3338282) Show SMILES Cc1cnn(CC2CC2)c1Cc1cc(C)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C26H28N4O2/c1-16-4-9-23(20(10-16)11-24-17(2)13-27-30(24)14-19-6-7-19)29-15-21(12-25(31)32)22-8-5-18(3)28-26(22)29/h4-5,8-10,13,15,19H,6-7,11-12,14H2,1-3H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035076 (CHEMBL3338284) Show SMILES Cc1nnc(C2CC2)n1Cc1cc(Cl)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C23H22ClN5O2/c1-13-3-7-19-16(10-21(30)31)11-29(23(19)25-13)20-8-6-18(24)9-17(20)12-28-14(2)26-27-22(28)15-4-5-15/h3,6-9,11,15H,4-5,10,12H2,1-2H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50154762 (CHEMBL3774971) Show SMILES COc1ccc(c(Cn2c(C)c(CC(O)=O)c3ccc(C)nc23)c1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C25H23FN2O5S/c1-15-4-10-21-22(13-24(29)30)16(2)28(25(21)27-15)14-17-12-19(33-3)7-11-23(17)34(31,32)20-8-5-18(26)6-9-20/h4-12H,13-14H2,1-3H3,(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter				Eur J Med Chem 113: 102-33 (2016) Article DOI: 10.1016/j.ejmech.2016.02.023 BindingDB Entry DOI: 10.7270/Q2K64KXM
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035019 (CHEMBL3343118) Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)c2ccc(C)nn12)C(F)(F)F)C(=O)C1CC1 Show InChI InChI=1S/C24H24F3N3O3/c1-3-29(23(33)15-5-6-15)13-17-10-18(24(25,26)27)7-8-19(17)21-11-16(12-22(31)32)20-9-4-14(2)28-30(20)21/h4,7-11,15H,3,5-6,12-13H2,1-2H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034960 (CHEMBL3342994) Show SMILES CCN(Cc1cc(ccc1-c1nn(CC(O)=O)c2cccc(F)c12)C(F)(F)F)C(=O)C1CC1 Show InChI InChI=1S/C23H21F4N3O3/c1-2-29(22(33)13-6-7-13)11-14-10-15(23(25,26)27)8-9-16(14)21-20-17(24)4-3-5-18(20)30(28-21)12-19(31)32/h3-5,8-10,13H,2,6-7,11-12H2,1H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035026 (CHEMBL3343124) Show SMILES CCN(Cc1cc(ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(F)(F)F)C(=O)NCc1ccccc1 Show InChI InChI=1S/C28H27F3N4O3/c1-3-34(27(38)32-15-19-7-5-4-6-8-19)16-21-13-22(28(29,30)31)10-12-24(21)35-17-20(14-25(36)37)23-11-9-18(2)33-26(23)35/h4-13,17H,3,14-16H2,1-2H3,(H,32,38)(H,36,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change preincubated for 10 mins wi...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034979 (CHEMBL3343106) Show SMILES CCN(Cc1cc(F)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(=O)C1CC1 Show InChI InChI=1S/C23H24FN3O3/c1-3-26(23(30)15-5-6-15)12-17-10-18(24)7-9-20(17)27-13-16(11-21(28)29)19-8-4-14(2)25-22(19)27/h4,7-10,13,15H,3,5-6,11-12H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034980 (CHEMBL3338153) Show SMILES CCN(Cc1ccccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(=O)C1CC1 Show InChI InChI=1S/C23H25N3O3/c1-3-25(23(29)16-9-10-16)13-17-6-4-5-7-20(17)26-14-18(12-21(27)28)19-11-8-15(2)24-22(19)26/h4-8,11,14,16H,3,9-10,12-13H2,1-2H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035026 (CHEMBL3343124) Show SMILES CCN(Cc1cc(ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(F)(F)F)C(=O)NCc1ccccc1 Show InChI InChI=1S/C28H27F3N4O3/c1-3-34(27(38)32-15-19-7-5-4-6-8-19)16-21-13-22(28(29,30)31)10-12-24(21)35-17-20(14-25(36)37)23-11-9-18(2)33-26(23)35/h4-13,17H,3,14-16H2,1-2H3,(H,32,38)(H,36,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035023 (CHEMBL3343121) Show SMILES CCN(Cc1cc(ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(F)(F)F)C(=O)COC Show InChI InChI=1S/C23H24F3N3O4/c1-4-28(20(30)13-33-3)11-16-9-17(23(24,25)26)6-8-19(16)29-12-15(10-21(31)32)18-7-5-14(2)27-22(18)29/h5-9,12H,4,10-11,13H2,1-3H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change preincubated for 10 mins wi...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034980 (CHEMBL3338153) Show SMILES CCN(Cc1ccccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(=O)C1CC1 Show InChI InChI=1S/C23H25N3O3/c1-3-25(23(29)16-9-10-16)13-17-6-4-5-7-20(17)26-14-18(12-21(27)28)19-11-8-15(2)24-22(19)26/h4-8,11,14,16H,3,9-10,12-13H2,1-2H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035081 (CHEMBL3338289) Show SMILES Cc1noc(C)c1Cc1cc(ccc1-c1cn(CC(O)=O)c2ccc(C)nc12)C(F)(F)F Show InChI InChI=1S/C23H20F3N3O3/c1-12-4-7-20-22(27-12)19(10-29(20)11-21(30)31)17-6-5-16(23(24,25)26)8-15(17)9-18-13(2)28-32-14(18)3/h4-8,10H,9,11H2,1-3H3,(H,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035085 (CHEMBL3338293) Show SMILES Cc1noc(C2CC2)c1Cc1cc(ccc1-c1cc(CC(O)=O)n2ccc(C)nc12)C(F)(F)F Show InChI InChI=1S/C25H22F3N3O3/c1-13-7-8-31-18(12-22(32)33)11-21(24(31)29-13)19-6-5-17(25(26,27)28)9-16(19)10-20-14(2)30-34-23(20)15-3-4-15/h5-9,11,15H,3-4,10,12H2,1-2H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035080 (CHEMBL3338288) Show SMILES Cc1nnc(CCc2ccccc2)n1Cc1cc(Cl)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C28H26ClN5O2/c1-18-8-11-24-21(15-27(35)36)16-34(28(24)30-18)25-12-10-23(29)14-22(25)17-33-19(2)31-32-26(33)13-9-20-6-4-3-5-7-20/h3-8,10-12,14,16H,9,13,15,17H2,1-2H3,(H,35,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035089 (CHEMBL3338297) Show SMILES Cc1noc(C2CC2)c1Cc1cc(ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(F)(F)F Show InChI InChI=1S/C25H22F3N3O3/c1-13-3-7-19-17(11-22(32)33)12-31(24(19)29-13)21-8-6-18(25(26,27)28)9-16(21)10-20-14(2)30-34-23(20)15-4-5-15/h3,6-9,12,15H,4-5,10-11H2,1-2H3,(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50154760 (CHEMBL3774449) Show SMILES COc1ccc(c(Cc2c(C)c(CC(O)=O)c3ccncn23)c1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C24H21FN2O5S/c1-15-20(13-24(28)29)21-9-10-26-14-27(21)22(15)12-16-11-18(32-2)5-8-23(16)33(30,31)19-6-3-17(25)4-7-19/h3-11,14H,12-13H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter				Eur J Med Chem 113: 102-33 (2016) Article DOI: 10.1016/j.ejmech.2016.02.023 BindingDB Entry DOI: 10.7270/Q2K64KXM
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034809 (CHEMBL3338090) Show SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(CCNC2=O)n1CC(O)=O Show InChI InChI=1S/C23H22N2O5S/c1-15-18(22-19(11-12-24-23(22)28)25(15)14-21(26)27)13-16-7-5-6-10-20(16)31(29,30)17-8-3-2-4-9-17/h2-10H,11-14H2,1H3,(H,24,28)(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter				Eur J Med Chem 113: 102-33 (2016) Article DOI: 10.1016/j.ejmech.2016.02.023 BindingDB Entry DOI: 10.7270/Q2K64KXM
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034981 (CHEMBL3343107) Show SMILES CCN(Cc1cc(Cl)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(=O)C1CC1 Show InChI InChI=1S/C23H24ClN3O3/c1-3-26(23(30)15-5-6-15)12-17-10-18(24)7-9-20(17)27-13-16(11-21(28)29)19-8-4-14(2)25-22(19)27/h4,7-10,13,15H,3,5-6,11-12H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034983 (CHEMBL3343109) Show SMILES CCN(Cc1cc(OC(F)(F)F)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(=O)C1CC1 Show InChI InChI=1S/C24H24F3N3O4/c1-3-29(23(33)15-5-6-15)12-17-10-18(34-24(25,26)27)7-9-20(17)30-13-16(11-21(31)32)19-8-4-14(2)28-22(19)30/h4,7-10,13,15H,3,5-6,11-12H2,1-2H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034982 (CHEMBL3343108) Show SMILES CCN(Cc1cc(C)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(=O)C1CC1 Show InChI InChI=1S/C24H27N3O3/c1-4-26(24(30)17-7-8-17)13-19-11-15(2)5-10-21(19)27-14-18(12-22(28)29)20-9-6-16(3)25-23(20)27/h5-6,9-11,14,17H,4,7-8,12-13H2,1-3H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035024 (CHEMBL3343122) Show SMILES CCN(Cc1cc(ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(F)(F)F)C(=O)Cc1ccccc1 Show InChI InChI=1S/C28H26F3N3O3/c1-3-33(25(35)13-19-7-5-4-6-8-19)16-21-14-22(28(29,30)31)10-12-24(21)34-17-20(15-26(36)37)23-11-9-18(2)32-27(23)34/h4-12,14,17H,3,13,15-16H2,1-2H3,(H,36,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035077 (CHEMBL3338285) Show SMILES Cc1nnc(C2CC2)n1Cc1cc(ccc1-c1cn(CC(O)=O)c2ccc(F)cc12)C(F)(F)F Show InChI InChI=1S/C24H20F4N4O2/c1-13-29-30-23(14-2-3-14)32(13)10-15-8-16(24(26,27)28)4-6-18(15)20-11-31(12-22(33)34)21-7-5-17(25)9-19(20)21/h4-9,11,14H,2-3,10,12H2,1H3,(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035092 (CHEMBL3338300) Show SMILES Cc1ccc2c(CC(O)=O)cn(-c3ccc(Cl)cc3Cc3c(noc3C3CC3)C3CC3)c2n1 Show InChI InChI=1S/C26H24ClN3O3/c1-14-2-8-20-18(12-23(31)32)13-30(26(20)28-14)22-9-7-19(27)10-17(22)11-21-24(15-3-4-15)29-33-25(21)16-5-6-16/h2,7-10,13,15-16H,3-6,11-12H2,1H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035153 (CHEMBL3338302) Show SMILES Cc1noc(C)c1-c1cccc(c1)-c1c(C)n(CC(O)=O)c2ccc(F)cc12 Show InChI InChI=1S/C22H19FN2O3/c1-12-21(14(3)28-24-12)15-5-4-6-16(9-15)22-13(2)25(11-20(26)27)19-8-7-17(23)10-18(19)22/h4-10H,11H2,1-3H3,(H,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 (unknown origin) stably expressed in PGD2-stimulated CHO.K1 cells preincubated for 1 hr by radio-labelled [35S]-GTPgamma...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035037 (CHEMBL3338268) Show SMILES Cc1cnn(C)c1Cc1cc(F)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12 Show InChI InChI=1S/C22H21FN4O2/c1-13-11-24-26(3)20(13)9-15-8-17(23)5-7-19(15)27-12-16(10-21(28)29)18-6-4-14(2)25-22(18)27/h4-8,11-12H,9-10H2,1-3H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change after 10 mins by fluorescen...				Bioorg Med Chem Lett 24: 5127-33 (2014) Article DOI: 10.1016/j.bmcl.2014.08.028 BindingDB Entry DOI: 10.7270/Q27P911Z
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50154760 (CHEMBL3774449) Show SMILES COc1ccc(c(Cc2c(C)c(CC(O)=O)c3ccncn23)c1)S(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C24H21FN2O5S/c1-15-20(13-24(28)29)21-9-10-26-14-27(21)22(15)12-16-11-18(32-2)5-8-23(16)33(30,31)19-6-3-17(25)4-7-19/h3-11,14H,12-13H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTH2 receptor in human eosinophils by ESC assay				Eur J Med Chem 113: 102-33 (2016) Article DOI: 10.1016/j.ejmech.2016.02.023 BindingDB Entry DOI: 10.7270/Q2K64KXM
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034959 (CHEMBL3342993) Show SMILES CCN(Cc1cc(ccc1-c1nn(CC(O)=O)c2cccc(Cl)c12)C(F)(F)F)C(=O)C1CC1 Show InChI InChI=1S/C23H21ClF3N3O3/c1-2-29(22(33)13-6-7-13)11-14-10-15(23(25,26)27)8-9-16(14)21-20-17(24)4-3-5-18(20)30(28-21)12-19(31)32/h3-5,8-10,13H,2,6-7,11-12H2,1H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034979 (CHEMBL3343106) Show SMILES CCN(Cc1cc(F)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(=O)C1CC1 Show InChI InChI=1S/C23H24FN3O3/c1-3-26(23(30)15-5-6-15)12-17-10-18(24)7-9-20(17)27-13-16(11-21(28)29)19-8-4-14(2)25-22(19)27/h4,7-10,13,15H,3,5-6,11-12H2,1-2H3,(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change preincubated for 10 mins wi...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034983 (CHEMBL3343109) Show SMILES CCN(Cc1cc(OC(F)(F)F)ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(=O)C1CC1 Show InChI InChI=1S/C24H24F3N3O4/c1-3-29(23(33)15-5-6-15)12-17-10-18(34-24(25,26)27)7-9-20(17)30-13-16(11-21(31)32)19-8-4-14(2)28-22(19)30/h4,7-10,13,15H,3,5-6,11-12H2,1-2H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change preincubated for 10 mins wi...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50034995 (CHEMBL3343117) Show SMILES CCN(Cc1cc(ccc1-c1cc(CC(O)=O)n2ccc(C)nc12)C(F)(F)F)C(=O)C1CC1 Show InChI InChI=1S/C24H24F3N3O3/c1-3-29(23(33)15-4-5-15)13-16-10-17(24(25,26)27)6-7-19(16)20-11-18(12-21(31)32)30-9-8-14(2)28-22(20)30/h6-11,15H,3-5,12-13H2,1-2H3,(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM50035022 (CHEMBL3343120) Show SMILES CCN(Cc1cc(ccc1-n1cc(CC(O)=O)c2ccc(C)nc12)C(F)(F)F)C(=O)CC1CC1 Show InChI InChI=1S/C25H26F3N3O3/c1-3-30(22(32)10-16-5-6-16)13-18-11-19(25(26,27)28)7-9-21(18)31-14-17(12-23(33)34)20-8-4-15(2)29-24(20)31/h4,7-9,11,14,16H,3,5-6,10,12-13H2,1-2H3,(H,33,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Rhône-Poulenc Rorer Curated by ChEMBL					Assay Description Antagonist activity at CRTh2 receptor (unknown origin) overexpressed in CHOK1 cell membranes assessed as inhibition of [35S]-GTPgammaS binding measur...				Bioorg Med Chem Lett 24: 5123-6 (2014) Article DOI: 10.1016/j.bmcl.2014.08.029 BindingDB Entry DOI: 10.7270/Q2CF9RRW
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 197 total )  |  Next  |  Last  >>

Jump to: