Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lanosterol synthase (Rattus norvegicus) | BDBM50003025 (1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003025 (1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003025 (1-((4aS,5S,6S,8aS)-6-Hydroxy-5,8a-dimethyl-octahyd...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003026 (1-(6-Hydroxy-5,8a-dimethyl-octahydro-isoquinolin-2...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281884 (2-(1-Dodecyl-piperidin-4-yl)-propan-1-ol | CHEMBL1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003032 ((4aS,5S,6S,8aS)-2-Dodecyl-5,8a-dimethyl-decahydro-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003032 ((4aS,5S,6S,8aS)-2-Dodecyl-5,8a-dimethyl-decahydro-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281889 (1-(1,5,9-Trimethyl-decyl)-piperidine | CHEMBL41817...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281895 (1-(1,5,9-Trimethyl-decyl)-piperidin-4-ol | CHEMBL1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003027 ((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-d...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003027 ((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-(1,5,9-trimethyl-d...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281888 (2-[1-(1,5,9-Trimethyl-decyl)-piperidin-4-yl]-propa...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281893 ((4aS,5S,6S,8aS)-5,8a-Dimethyl-2-((E)-1,5,9-trimeth...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281885 (1-Dodecyl-piperidin-3-ol | CHEMBL17348) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281886 (1-(1,5,9-Trimethyl-decyl)-piperidin-3-ol | CHEMBL1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003030 ((2S,4aS,8aR)-1,1,4a-Trimethyl-decahydro-naphthalen...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281891 (1-Dodecyl-piperidin-4-ol | CHEMBL17729) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281890 (1-[4-(2-Hydroxy-1-methyl-ethyl)-piperidin-1-yl]-tr...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281887 (1-((E)-1,5,9-Trimethyl-deca-4,8-dienyl)-piperidin-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003028 (2-(Dodecane-1-sulfinyl)-5,8a-dimethyl-decahydro-is...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281892 (1-((E)-1,5,9-Trimethyl-deca-4,8-dienyl)-piperidine...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281896 (1-((E)-1,5,9-Trimethyl-deca-4,8-dienyl)-piperidin-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003031 (1-(6-Hydroxy-5,8a-dimethyl-octahydro-isoquinolin-2...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50281894 (2-(1-Benzyl-piperidin-4-yl)-propan-1-ol | CHEMBL28...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 5.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory concentration against purified rat liver Oxidosqualene cyclase (OSC) | Bioorg Med Chem Lett 3: 1175-1178 (1993) Article DOI: 10.1016/S0960-894X(00)80309-1 BindingDB Entry DOI: 10.7270/Q2BK1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lanosterol synthase (Rattus norvegicus) | BDBM50003029 (2-(Dodecane-1-sulfonyl)-5,8a-dimethyl-decahydro-is...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Marion Merrell Dow Research Institute Curated by ChEMBL | Assay Description Inhibitory activity against Oxidosqualene-lanosterol cyclase enzyme obtained from rat liver | J Med Chem 35: 3581-3 (1992) BindingDB Entry DOI: 10.7270/Q24T6H9N | |||||||||||
More data for this Ligand-Target Pair |