Compile Data Set for Download or QSAR

Found 117 hits with Last Name = 'menegazzi' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50502547 (CHEMBL4581662) Show SMILES O=C1CCc2ccccc2N1CCCCN1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C23H35N3O/c27-23-13-12-20-8-4-5-11-22(20)26(23)15-7-6-14-24-16-18-25(19-17-24)21-9-2-1-3-10-21/h4-5,8,11,21H,1-3,6-7,9-10,12-19H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502547 (CHEMBL4581662) Show SMILES O=C1CCc2ccccc2N1CCCCN1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C23H35N3O/c27-23-13-12-20-8-4-5-11-22(20)26(23)15-7-6-14-24-16-18-25(19-17-24)21-9-2-1-3-10-21/h4-5,8,11,21H,1-3,6-7,9-10,12-19H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502557 (CHEMBL4459690) Show SMILES O=C1CCc2ccccc2N1CCCCN1CCC2(CC1)OCc1ccccc21 Show InChI InChI=1S/C25H30N2O2/c28-24-12-11-20-7-2-4-10-23(20)27(24)16-6-5-15-26-17-13-25(14-18-26)22-9-3-1-8-21(22)19-29-25/h1-4,7-10H,5-6,11-19H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502554 (CHEMBL4533030) Show SMILES CN(CCCCN1C(=O)CCc2ccccc12)Cc1ccc(C)cc1C Show InChI InChI=1S/C23H30N2O/c1-18-10-11-21(19(2)16-18)17-24(3)14-6-7-15-25-22-9-5-4-8-20(22)12-13-23(25)26/h4-5,8-11,16H,6-7,12-15,17H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50540585 (CHEMBL4639180) Show SMILES O=C(N1CCCN(Cc2ccccc2)CC1)c1cc2ccccc2o1 Show InChI InChI=1S/C21H22N2O2/c24-21(20-15-18-9-4-5-10-19(18)25-20)23-12-6-11-22(13-14-23)16-17-7-2-1-3-8-17/h1-5,7-10,15H,6,11-14,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502558 (CHEMBL4449269) Show SMILES Fc1ccc(cc1)N1CCN(CCCCN2C(=O)CCc3ccccc23)CC1 Show InChI InChI=1S/C23H28FN3O/c24-20-8-10-21(11-9-20)26-17-15-25(16-18-26)13-3-4-14-27-22-6-2-1-5-19(22)7-12-23(27)28/h1-2,5-6,8-11H,3-4,7,12-18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502548 (CHEMBL4446466) Show SMILES O=c1oc(nn1CCCCN1CCC2(CC1)OCc1ccccc21)-c1ccccc1 Show InChI InChI=1S/C24H27N3O3/c28-23-27(25-22(30-23)19-8-2-1-3-9-19)15-7-6-14-26-16-12-24(13-17-26)21-11-5-4-10-20(21)18-29-24/h1-5,8-11H,6-7,12-18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50083351 ((+/-)-[2-(4-benzylpiperidino)-1-(4-hydroxyphenyl)-...) Show SMILES CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by s...				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502555 (CHEMBL4445874) Show SMILES C[C@@H]([C@H](O)N1CCC(Cc2ccccc2)CC1)c1ccc(O)cc1 |r| Show InChI InChI=1S/C21H27NO2/c1-16(19-7-9-20(23)10-8-19)21(24)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3/t16-,21+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502553 (CHEMBL4439170) Show SMILES COc1cc2CCN(CCCCN3C(=O)CCc4ccccc34)Cc2cc1OC Show InChI InChI=1S/C24H30N2O3/c1-28-22-15-19-11-14-25(17-20(19)16-23(22)29-2)12-5-6-13-26-21-8-4-3-7-18(21)9-10-24(26)27/h3-4,7-8,15-16H,5-6,9-14,17H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50502558 (CHEMBL4449269) Show SMILES Fc1ccc(cc1)N1CCN(CCCCN2C(=O)CCc3ccccc23)CC1 Show InChI InChI=1S/C23H28FN3O/c24-20-8-10-21(11-9-20)26-17-15-25(16-18-26)13-3-4-14-27-22-6-2-1-5-19(22)7-12-23(27)28/h1-2,5-6,8-11H,3-4,7,12-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50502548 (CHEMBL4446466) Show SMILES O=c1oc(nn1CCCCN1CCC2(CC1)OCc1ccccc21)-c1ccccc1 Show InChI InChI=1S/C24H27N3O3/c28-23-27(25-22(30-23)19-8-2-1-3-9-19)15-7-6-14-26-16-12-24(13-17-26)21-11-5-4-10-20(21)18-29-24/h1-5,8-11H,6-7,12-18H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50466974 (CHEMBL4285413) Show SMILES CCCCCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O Show InChI InChI=1S/C20H32N2O/c1-3-4-8-13-22(18(2)23)17-20-11-14-21(15-12-20)16-19-9-6-5-7-10-19/h5-7,9-10,20H,3-4,8,11-17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting				Bioorg Med Chem Lett 28: 3206-3209 (2018) Article DOI: 10.1016/j.bmcl.2018.08.016 BindingDB Entry DOI: 10.7270/Q2QN69FH
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50502557 (CHEMBL4459690) Show SMILES O=C1CCc2ccccc2N1CCCCN1CCC2(CC1)OCc1ccccc21 Show InChI InChI=1S/C25H30N2O2/c28-24-12-11-20-7-2-4-10-23(20)27(24)16-6-5-15-26-17-13-25(14-18-26)22-9-3-1-8-21(22)19-29-25/h1-4,7-10H,5-6,11-19H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50540586 (CHEMBL4633788) Show SMILES O=C(N1CCCN(Cc2ccccc2)CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C22H23N3O/c26-22(21-12-11-19-9-4-5-10-20(19)23-21)25-14-6-13-24(15-16-25)17-18-7-2-1-3-8-18/h1-5,7-12H,6,13-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50502548 (CHEMBL4446466) Show SMILES O=c1oc(nn1CCCCN1CCC2(CC1)OCc1ccccc21)-c1ccccc1 Show InChI InChI=1S/C24H27N3O3/c28-23-27(25-22(30-23)19-8-2-1-3-9-19)15-7-6-14-26-16-12-24(13-17-26)21-11-5-4-10-20(21)18-29-24/h1-5,8-11H,6-7,12-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50466983 (CHEMBL4277337) Show SMILES CCN(CC1CCN(Cc2ccc(Cl)cc2Cl)CC1)C(C)=O Show InChI InChI=1S/C17H24Cl2N2O/c1-3-21(13(2)22)11-14-6-8-20(9-7-14)12-15-4-5-16(18)10-17(15)19/h4-5,10,14H,3,6-9,11-12H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-DTG from sigma2 receptor in rat liver membranes after 120 mins by liquid scintillation counting				Bioorg Med Chem Lett 28: 3206-3209 (2018) Article DOI: 10.1016/j.bmcl.2018.08.016 BindingDB Entry DOI: 10.7270/Q2QN69FH
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50502561 (CHEMBL4446431) Show SMILES CN(CCCCn1nc(oc1=O)-c1ccccc1)Cc1ccc(C)cc1C Show InChI InChI=1S/C22H27N3O2/c1-17-11-12-20(18(2)15-17)16-24(3)13-7-8-14-25-22(26)27-21(23-25)19-9-5-4-6-10-19/h4-6,9-12,15H,7-8,13-14,16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50540592 (CHEMBL4643805) Show SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2cc3ccccc3o2)c(C)c1 Show InChI InChI=1S/C23H26N2O2/c1-17-8-9-20(18(2)14-17)16-24-10-5-11-25(13-12-24)23(26)22-15-19-6-3-4-7-21(19)27-22/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50502561 (CHEMBL4446431) Show SMILES CN(CCCCn1nc(oc1=O)-c1ccccc1)Cc1ccc(C)cc1C Show InChI InChI=1S/C22H27N3O2/c1-17-11-12-20(18(2)15-17)16-24(3)13-7-8-14-25-22(26)27-21(23-25)19-9-5-4-6-10-19/h4-6,9-12,15H,7-8,13-14,16H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50502558 (CHEMBL4449269) Show SMILES Fc1ccc(cc1)N1CCN(CCCCN2C(=O)CCc3ccccc23)CC1 Show InChI InChI=1S/C23H28FN3O/c24-20-8-10-21(11-9-20)26-17-15-25(16-18-26)13-3-4-14-27-22-6-2-1-5-19(22)7-12-23(27)28/h1-2,5-6,8-11H,3-4,7,12-18H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50502547 (CHEMBL4581662) Show SMILES O=C1CCc2ccccc2N1CCCCN1CCN(CC1)C1CCCCC1 Show InChI InChI=1S/C23H35N3O/c27-23-13-12-20-8-4-5-11-22(20)26(23)15-7-6-14-24-16-18-25(19-17-24)21-9-2-1-3-10-21/h4-5,8,11,21H,1-3,6-7,9-10,12-19H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502551 (CHEMBL4451677) Show SMILES O=c1oc(nn1CCCCN1CCN(CC1)C1CCCCC1)-c1ccccc1 Show InChI InChI=1S/C22H32N4O2/c27-22-26(23-21(28-22)19-9-3-1-4-10-19)14-8-7-13-24-15-17-25(18-16-24)20-11-5-2-6-12-20/h1,3-4,9-10,20H,2,5-8,11-18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502561 (CHEMBL4446431) Show SMILES CN(CCCCn1nc(oc1=O)-c1ccccc1)Cc1ccc(C)cc1C Show InChI InChI=1S/C22H27N3O2/c1-17-11-12-20(18(2)15-17)16-24(3)13-7-8-14-25-22(26)27-21(23-25)19-9-5-4-6-10-19/h4-6,9-12,15H,7-8,13-14,16H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502556 (CHEMBL4446009) Show SMILES COc1cc2CCN(CCCCn3nc(oc3=O)-c3ccccc3)Cc2cc1OC Show InChI InChI=1S/C23H27N3O4/c1-28-20-14-18-10-13-25(16-19(18)15-21(20)29-2)11-6-7-12-26-23(27)30-22(24-26)17-8-4-3-5-9-17/h3-5,8-9,14-15H,6-7,10-13,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50540592 (CHEMBL4643805) Show SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2cc3ccccc3o2)c(C)c1 Show InChI InChI=1S/C23H26N2O2/c1-17-8-9-20(18(2)14-17)16-24-10-5-11-25(13-12-24)23(26)22-15-19-6-3-4-7-21(19)27-22/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50540593 (CHEMBL4640137) Show SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2ccc3ccccc3n2)c(C)c1 Show InChI InChI=1S/C24H27N3O/c1-18-8-9-21(19(2)16-18)17-26-12-5-13-27(15-14-26)24(28)23-11-10-20-6-3-4-7-22(20)25-23/h3-4,6-11,16H,5,12-15,17H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50502554 (CHEMBL4533030) Show SMILES CN(CCCCN1C(=O)CCc2ccccc12)Cc1ccc(C)cc1C Show InChI InChI=1S/C23H30N2O/c1-18-10-11-21(19(2)16-18)17-24(3)14-6-7-15-25-22-9-5-4-8-20(22)12-13-23(25)26/h4-5,8-11,16H,6-7,12-15,17H2,1-3H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50466970 (CHEMBL4278696) Show SMILES CCCCCN(CC1CCN(Cc2ccc(Cl)cc2)CC1)C(C)=O Show InChI InChI=1S/C20H31ClN2O/c1-3-4-5-12-23(17(2)24)16-19-10-13-22(14-11-19)15-18-6-8-20(21)9-7-18/h6-9,19H,3-5,10-16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting				Bioorg Med Chem Lett 28: 3206-3209 (2018) Article DOI: 10.1016/j.bmcl.2018.08.016 BindingDB Entry DOI: 10.7270/Q2QN69FH
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50466984 (CHEMBL4284597) Show SMILES CCCCN(CC1CCN(Cc2ccc(Cl)cc2)CC1)C(C)=O Show InChI InChI=1S/C19H29ClN2O/c1-3-4-11-22(16(2)23)15-18-9-12-21(13-10-18)14-17-5-7-19(20)8-6-17/h5-8,18H,3-4,9-15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting				Bioorg Med Chem Lett 28: 3206-3209 (2018) Article DOI: 10.1016/j.bmcl.2018.08.016 BindingDB Entry DOI: 10.7270/Q2QN69FH
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50502557 (CHEMBL4459690) Show SMILES O=C1CCc2ccccc2N1CCCCN1CCC2(CC1)OCc1ccccc21 Show InChI InChI=1S/C25H30N2O2/c28-24-12-11-20-7-2-4-10-23(20)27(24)16-6-5-15-26-17-13-25(14-18-26)22-9-3-1-8-21(22)19-29-25/h1-4,7-10H,5-6,11-19H2	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50502551 (CHEMBL4451677) Show SMILES O=c1oc(nn1CCCCN1CCN(CC1)C1CCCCC1)-c1ccccc1 Show InChI InChI=1S/C22H32N4O2/c27-22-26(23-21(28-22)19-9-3-1-4-10-19)14-8-7-13-24-15-17-25(18-16-24)20-11-5-2-6-12-20/h1,3-4,9-10,20H,2,5-8,11-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50540593 (CHEMBL4640137) Show SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2ccc3ccccc3n2)c(C)c1 Show InChI InChI=1S/C24H27N3O/c1-18-8-9-21(19(2)16-18)17-26-12-5-13-27(15-14-26)24(28)23-11-10-20-6-3-4-7-22(20)25-23/h3-4,6-11,16H,5,12-15,17H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50466976 (CHEMBL4281986) Show SMILES CCCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O Show InChI InChI=1S/C18H28N2O/c1-3-11-20(16(2)21)15-18-9-12-19(13-10-18)14-17-7-5-4-6-8-17/h4-8,18H,3,9-15H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting				Bioorg Med Chem Lett 28: 3206-3209 (2018) Article DOI: 10.1016/j.bmcl.2018.08.016 BindingDB Entry DOI: 10.7270/Q2QN69FH
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50540588 (CHEMBL4640809) Show SMILES O=C(N1CCCN(Cc2ccccc2)CC1)c1cccc2ccccc12 Show InChI InChI=1S/C23H24N2O/c26-23(22-13-6-11-20-10-4-5-12-21(20)22)25-15-7-14-24(16-17-25)18-19-8-2-1-3-9-19/h1-6,8-13H,7,14-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50502553 (CHEMBL4439170) Show SMILES COc1cc2CCN(CCCCN3C(=O)CCc4ccccc34)Cc2cc1OC Show InChI InChI=1S/C24H30N2O3/c1-28-22-15-19-11-14-25(17-20(19)16-23(22)29-2)12-5-6-13-26-21-8-4-3-7-18(21)9-10-24(26)27/h3-4,7-8,15-16H,5-6,9-14,17H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50540586 (CHEMBL4633788) Show SMILES O=C(N1CCCN(Cc2ccccc2)CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C22H23N3O/c26-22(21-12-11-19-9-4-5-10-20(19)23-21)25-14-6-13-24(15-16-25)17-18-7-2-1-3-8-18/h1-5,7-12H,6,13-17H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50540585 (CHEMBL4639180) Show SMILES O=C(N1CCCN(Cc2ccccc2)CC1)c1cc2ccccc2o1 Show InChI InChI=1S/C21H22N2O2/c24-21(20-15-18-9-4-5-10-19(18)25-20)23-12-6-11-22(13-14-23)16-17-7-2-1-3-8-17/h1-5,7-10,15H,6,11-14,16H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50466973 (CHEMBL4289069) Show SMILES CC(=O)N(CC1CCCCC1)CC1CCN(Cc2ccc(Cl)cc2Cl)CC1 Show InChI InChI=1S/C22H32Cl2N2O/c1-17(27)26(14-18-5-3-2-4-6-18)15-19-9-11-25(12-10-19)16-20-7-8-21(23)13-22(20)24/h7-8,13,18-19H,2-6,9-12,14-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting				Bioorg Med Chem Lett 28: 3206-3209 (2018) Article DOI: 10.1016/j.bmcl.2018.08.016 BindingDB Entry DOI: 10.7270/Q2QN69FH
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50009307 (DITOLYLGUANIDINE | Di-o-tolylguanidine) Show SMILES Cc1ccccc1NC(=N)Nc1ccccc1C Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Rattus norvegicus (Rat))	BDBM50009307 (DITOLYLGUANIDINE | Di-o-tolylguanidine) Show SMILES Cc1ccccc1NC(=N)Nc1ccccc1C Show InChI InChI=1S/C15H17N3/c1-11-7-3-5-9-13(11)17-15(16)18-14-10-6-4-8-12(14)2/h3-10H,1-2H3,(H3,16,17,18)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-Di-o-tolylguanidine from sigma-2 receptor in rat liver membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502559 (CHEMBL4463741) Show SMILES [O-][N+](=O)c1ccc2CCN(CCCCN3C(=O)CCc4ccccc34)Cc2c1 Show InChI InChI=1S/C22H25N3O3/c26-22-10-8-18-5-1-2-6-21(18)24(22)13-4-3-12-23-14-11-17-7-9-20(25(27)28)15-19(17)16-23/h1-2,5-7,9,15H,3-4,8,10-14,16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50466982 (CHEMBL4277464) Show SMILES CC(=O)N(CC1CCCCC1)CC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C22H34N2O/c1-19(25)24(17-21-10-6-3-7-11-21)18-22-12-14-23(15-13-22)16-20-8-4-2-5-9-20/h2,4-5,8-9,21-22H,3,6-7,10-18H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting				Bioorg Med Chem Lett 28: 3206-3209 (2018) Article DOI: 10.1016/j.bmcl.2018.08.016 BindingDB Entry DOI: 10.7270/Q2QN69FH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50540592 (CHEMBL4643805) Show SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2cc3ccccc3o2)c(C)c1 Show InChI InChI=1S/C23H26N2O2/c1-17-8-9-20(18(2)14-17)16-24-10-5-11-25(13-12-24)23(26)22-15-19-6-3-4-7-21(19)27-22/h3-4,6-9,14-15H,5,10-13,16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes co-expressing GluN1a incubated for 120 mins by s...				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50502554 (CHEMBL4533030) Show SMILES CN(CCCCN1C(=O)CCc2ccccc12)Cc1ccc(C)cc1C Show InChI InChI=1S/C23H30N2O/c1-18-10-11-21(19(2)16-18)17-24(3)14-6-7-15-25-22-9-5-4-8-20(22)12-13-23(25)26/h4-5,8-11,16H,6-7,12-15,17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50466972 (CHEMBL4292596) Show SMILES CCCCN(CC1CCN(Cc2ccccc2)CC1)C(C)=O Show InChI InChI=1S/C19H30N2O/c1-3-4-12-21(17(2)22)16-19-10-13-20(14-11-19)15-18-8-6-5-7-9-18/h5-9,19H,3-4,10-16H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in rat liver membranes after 120 mins by liquid scintillation counting				Bioorg Med Chem Lett 28: 3206-3209 (2018) Article DOI: 10.1016/j.bmcl.2018.08.016 BindingDB Entry DOI: 10.7270/Q2QN69FH
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human))	BDBM50502560 (CHEMBL4567801) Show SMILES Fc1ccc(cc1)N1CCN(CCCCn2nc(oc2=O)-c2ccccc2)CC1 Show InChI InChI=1S/C22H25FN4O2/c23-19-8-10-20(11-9-19)26-16-14-25(15-17-26)12-4-5-13-27-22(28)29-21(24-27)18-6-2-1-3-7-18/h1-3,6-11H,4-5,12-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou...				Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50540595 (CHEMBL4644807) Show SMILES Cc1ccc(CN2CCCN(CC2)C(=O)c2cccc3ccccc23)c(C)c1 Show InChI InChI=1S/C25H28N2O/c1-19-11-12-22(20(2)17-19)18-26-13-6-14-27(16-15-26)25(28)24-10-5-8-21-7-3-4-9-23(21)24/h3-5,7-12,17H,6,13-16,18H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Trieste Curated by ChEMBL					Assay Description Displacement of [3H]-(+)pentazocine from sigma-1 receptor in guinea pig brain membranes after 120 mins by scintillation counting method				ACS Med Chem Lett 11: 651-656 (2020) Article DOI: 10.1021/acsmedchemlett.9b00524 BindingDB Entry DOI: 10.7270/Q2ZS3134
					More data for this Ligand-Target Pair

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