null
SMILES: O=c1oc(nn1CCCCN1CCC2(CC1)OCc1ccccc21)-c1ccccc1
InChI Key: InChIKey=VUWZMKINVVTFBN-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sigma intracellular receptor 2 (Rattus norvegicus (Rat)) | BDBM50502548 (CHEMBL4446466) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [3H]-di-o-tolylguanidine from sigma2 receptor in rat liver membranes in the presence of sigma1 receptor ligand (+)-pentazocine incuba... | Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig)) | BDBM50502548 (CHEMBL4446466) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain cortex membranes incubated for 120 mins by solid scintillation counting... | Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 1/2B (Homo sapiens (Human)) | BDBM50502548 (CHEMBL4446466) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Trieste Curated by ChEMBL | Assay Description Displacement of [3H]ifenprodil from GluN1a/GluN2B (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by solid scintillation cou... | Eur J Med Chem 180: 268-282 (2019) Article DOI: 10.1016/j.ejmech.2019.07.012 BindingDB Entry DOI: 10.7270/Q2ST7T3Z | |||||||||||
More data for this Ligand-Target Pair |