Compile Data Set for Download or QSAR

Found 203 hits with Last Name = 'tokuyama' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	103	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cKit by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cKit by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT4 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188283 (6-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccsc3)c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-17-16(10-14)11-18-19(21-22-20(17)18)15-4-9-25-13-15/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188281 (4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihydroi...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c(n[nH]c-34)-c3ccc(O)cc3)c2)CC1 Show InChI InChI=1S/C22H24N4O/c1-25-8-10-26(11-9-25)14-15-2-7-19-17(12-15)13-20-21(23-24-22(19)20)16-3-5-18(27)6-4-16/h2-7,12,27H,8-11,13-14H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188290 (7-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...) Show SMILES CN1CCN(Cc2ccc3Cc4c([nH]nc4-c4ccccc4)-c3c2)CC1 Show InChI InChI=1S/C22H24N4/c1-25-9-11-26(12-10-25)15-16-7-8-18-14-20-21(17-5-3-2-4-6-17)23-24-22(20)19(18)13-16/h2-8,13H,9-12,14-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	601	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT1 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188275 (6-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3[nH]nc4-c3ccccc3)c2)CC1 Show InChI InChI=1S/C22H24N4/c1-25-9-11-26(12-10-25)15-16-7-8-19-18(13-16)14-20-21(23-24-22(19)20)17-5-3-2-4-6-17/h2-8,13H,9-12,14-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188292 (3-(thiophen-2-yl)-1,4-dihydroindeno[1,2-c]pyrazole...) Show SMILES C1c2ccccc2-c2n[nH]c(c12)-c1cccs1 Show InChI InChI=1S/C14H10N2S/c1-2-5-10-9(4-1)8-11-13(10)15-16-14(11)12-6-3-7-17-12/h1-7H,8H2,(H,15,16)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT1 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188271 (6-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-2-y...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3cccs3)c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-6-8-24(9-7-23)13-14-4-5-16-15(11-14)12-17-19(16)21-22-20(17)18-3-2-10-25-18/h2-5,10-11H,6-9,12-13H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188284 (3-phenyl-1,4-dihydroindeno[1,2-c]pyrazole | CHEMBL...) Show SMILES C1c2ccccc2-c2[nH]nc(c12)-c1ccccc1 Show InChI InChI=1S/C16H12N2/c1-2-6-11(7-3-1)15-14-10-12-8-4-5-9-13(12)16(14)18-17-15/h1-9H,10H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188269 (3-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1,4-d...) Show SMILES CN1CCN(Cc2ccc(cc2)-c2[nH]nc-3c2Cc2ccccc-32)CC1 Show InChI InChI=1S/C22H24N4/c1-25-10-12-26(13-11-25)15-16-6-8-17(9-7-16)21-20-14-18-4-2-3-5-19(18)22(20)24-23-21/h2-9H,10-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FLT4 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188277 (6-((4-methylpiperazin-1-yl)methyl)-3-(thiazol-5-yl...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3cncs3)c2)CC1 Show InChI InChI=1S/C19H21N5S/c1-23-4-6-24(7-5-23)11-13-2-3-15-14(8-13)9-16-18(15)21-22-19(16)17-10-20-12-25-17/h2-3,8,10,12H,4-7,9,11H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188289 (3-(3-((4-methylpiperazin-1-yl)methyl)phenyl)-1,4-d...) Show SMILES CN1CCN(Cc2cccc(c2)-c2[nH]nc-3c2Cc2ccccc-32)CC1 Show InChI InChI=1S/C22H24N4/c1-25-9-11-26(12-10-25)15-16-5-4-7-18(13-16)21-20-14-17-6-2-3-8-19(17)22(20)24-23-21/h2-8,13H,9-12,14-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188273 (6-((4-methylpiperazin-1-yl)methyl)-3-(5-methylthio...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3ccc(C)s3)c2)CC1 Show InChI InChI=1S/C21H24N4S/c1-14-3-6-19(26-14)21-18-12-16-11-15(4-5-17(16)20(18)22-23-21)13-25-9-7-24(2)8-10-25/h3-6,11H,7-10,12-13H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188274 (6-((4-methylpiperazin-1-yl)methyl)-3-(thiazol-4-yl...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3cscn3)c2)CC1 Show InChI InChI=1S/C19H21N5S/c1-23-4-6-24(7-5-23)10-13-2-3-15-14(8-13)9-16-18(15)21-22-19(16)17-11-25-12-20-17/h2-3,8,11-12H,4-7,9-10H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188279 (6-((4-methylpiperazin-1-yl)methyl)-3-(pyridin-3-yl...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c(n[nH]c-34)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C21H23N5/c1-25-7-9-26(10-8-25)14-15-4-5-18-17(11-15)12-19-20(23-24-21(18)19)16-3-2-6-22-13-16/h2-6,11,13H,7-10,12,14H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188265 (6-((4-methylpiperazin-1-yl)methyl)-3-(4-methylthio...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3cc(C)cs3)c2)CC1 Show InChI InChI=1S/C21H24N4S/c1-14-9-19(26-13-14)21-18-11-16-10-15(3-4-17(16)20(18)22-23-21)12-25-7-5-24(2)6-8-25/h3-4,9-10,13H,5-8,11-12H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188268 (5-((4-methylpiperazin-1-yl)methyl)-3-phenyl-1,4-di...) Show SMILES CN1CCN(Cc2cccc-3c2Cc2c-3[nH]nc2-c2ccccc2)CC1 Show InChI InChI=1S/C22H24N4/c1-25-10-12-26(13-11-25)15-17-8-5-9-18-19(17)14-20-21(23-24-22(18)20)16-6-3-2-4-7-16/h2-9H,10-15H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188287 (6-((4-methylpiperazin-1-yl)methyl)-3-(thiazol-2-yl...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c(n[nH]c-34)-c3nccs3)c2)CC1 Show InChI InChI=1S/C19H21N5S/c1-23-5-7-24(8-6-23)12-13-2-3-15-14(10-13)11-16-17(15)21-22-18(16)19-20-4-9-25-19/h2-4,9-10H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Tie2 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Lck by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FGFR by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Tie2 by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of EGFR by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188278 (3-(benzo[b]thiophen-2-yl)-6-((4-methylpiperazin-1-...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3cc4ccccc4s3)c2)CC1 Show InChI InChI=1S/C24H24N4S/c1-27-8-10-28(11-9-27)15-16-6-7-19-18(12-16)13-20-23(19)25-26-24(20)22-14-17-4-2-3-5-21(17)29-22/h2-7,12,14H,8-11,13,15H2,1H3,(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cMet by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of cMet by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of Lck by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188291 (6-((4-methylpiperazin-1-yl)methyl)-3-(3-methylthio...) Show SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3sccc3C)c2)CC1 Show InChI InChI=1S/C21H24N4S/c1-14-5-10-26-21(14)20-18-12-16-11-15(3-4-17(16)19(18)22-23-20)13-25-8-6-24(2)7-9-25/h3-5,10-11H,6-9,12-13H2,1-2H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of PDGFR by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of PDGFR by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1/2/3/4 (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of FGFR by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50188266 (7-((4-methylpiperazin-1-yl)methyl)-3-(thiophen-3-y...) Show SMILES CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H22N4S/c1-23-5-7-24(8-6-23)12-14-2-3-15-11-18-19(16-4-9-25-13-16)21-22-20(18)17(15)10-14/h2-4,9-10,13H,5-8,11-12H2,1H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of EGFR by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188286 (7-((1H-1,2,4-triazol-1-yl)methyl)-3-(thiophen-3-yl...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1cncn1 Show InChI InChI=1S/C17H13N5S/c1-2-12-6-15-16(13-3-4-23-8-13)20-21-17(15)14(12)5-11(1)7-22-10-18-9-19-22/h1-5,8-10H,6-7H2,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188276 (7-(2-(4-methylpiperazin-1-yl)ethyl)-3-(thiophen-3-...) Show SMILES CN1CCN(CCc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C21H24N4S/c1-24-7-9-25(10-8-24)6-4-15-2-3-16-13-19-20(17-5-11-26-14-17)22-23-21(19)18(16)12-15/h2-3,5,11-12,14H,4,6-10,13H2,1H3,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.43E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188272 (7-((1H-imidazol-1-yl)methyl)-3-(thiophen-3-yl)-1,4...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnc1 Show InChI InChI=1S/C18H14N4S/c1-2-13-8-16-17(14-3-6-23-10-14)20-21-18(16)15(13)7-12(1)9-22-5-4-19-11-22/h1-7,10-11H,8-9H2,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of KDR-mediated biotin-Ahx-AEEEYFFLFA-amide substrate phosphorylation in presence of 1 mM ATP by HTRF assay				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188285 (7-((4-isopropylpiperazin-1-yl)methyl)-3-(thiophen-...) Show SMILES CC(C)N1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C22H26N4S/c1-15(2)26-8-6-25(7-9-26)13-16-3-4-17-12-20-21(18-5-10-27-14-18)23-24-22(20)19(17)11-16/h3-5,10-11,14-15H,6-9,12-13H2,1-2H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188282 (7-((1H-1,2,3-triazol-1-yl)methyl)-3-(thiophen-3-yl...) Show SMILES C(c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1)n1ccnn1 Show InChI InChI=1S/C17H13N5S/c1-2-12-8-15-16(13-3-6-23-10-13)19-20-17(15)14(12)7-11(1)9-22-5-4-18-21-22/h1-7,10H,8-9H2,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188280 (4-((3-(thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyra...) Show SMILES O=CN1CCN(Cc2ccc3Cc4c(n[nH]c4-c4ccsc4)-c3c2)CC1 Show InChI InChI=1S/C20H20N4OS/c25-13-24-6-4-23(5-7-24)11-14-1-2-15-10-18-19(16-3-8-26-12-16)21-22-20(18)17(15)9-14/h1-3,8-9,12-13H,4-7,10-11H2,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.65E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188270 (CHEMBL213531 | N-ethyl-N-((3-(thiophen-3-yl)-1,4-d...) Show SMILES CCN(CC)Cc1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1 Show InChI InChI=1S/C19H21N3S/c1-3-22(4-2)11-13-5-6-14-10-17-18(15-7-8-23-12-15)20-21-19(17)16(14)9-13/h5-9,12H,3-4,10-11H2,1-2H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.24E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188288 (6-(4-methylpiperazin-1-yl)-3-(thiophen-2-yl)-1,4-d...) Show SMILES CN1CCN(CC1)c1ccc-2c(Cc3c-2n[nH]c3-c2cccs2)c1 Show InChI InChI=1S/C19H20N4S/c1-22-6-8-23(9-7-22)14-4-5-15-13(11-14)12-16-18(15)20-21-19(16)17-3-2-10-24-17/h2-5,10-11H,6-9,12H2,1H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.01E+6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50188267 ((4-methylpiperazin-1-yl)(3-(thiophen-3-yl)-1,4-dih...) Show SMILES CN1CCN(CC1)C(=O)c1ccc2Cc3c(n[nH]c3-c3ccsc3)-c2c1 Show InChI InChI=1S/C20H20N4OS/c1-23-5-7-24(8-6-23)20(25)14-3-2-13-10-17-18(15-4-9-26-12-15)21-22-19(17)16(13)11-14/h2-4,9,11-12H,5-8,10H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.08E+6	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of VEGF-induced human KDR phosphorylation transfected in NIH3T3 cells by ELISA				Bioorg Med Chem Lett 16: 4371-5 (2006) Article DOI: 10.1016/j.bmcl.2006.05.052 BindingDB Entry DOI: 10.7270/Q2QJ7GX6
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50596499 (CHEMBL5185420) Show SMILES OC(=O)Cc1cccc(OCCC2CCN(CC2)c2nc3ccc(Cl)cc3s2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128567 BindingDB Entry DOI: 10.7270/Q2KK9GV5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM28661 (2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)ph...) Show SMILES Cc1nc(sc1CSc1ccc(OCC(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C21H18F3NO3S2/c1-12-9-16(7-8-17(12)28-10-19(26)27)29-11-18-13(2)25-20(30-18)14-3-5-15(6-4-14)21(22,23)24/h3-9H,10-11H2,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128567 BindingDB Entry DOI: 10.7270/Q2KK9GV5
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50596500 (CHEMBL5180073) Show SMILES Cc1ccc(CC(O)=O)cc1OCCC1CCN(CC1)c1nc2ccc(Cl)cc2s1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	637	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.bmcl.2022.128567 BindingDB Entry DOI: 10.7270/Q2KK9GV5
					More data for this Ligand-Target Pair

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